RU2497524C2 - Внутрилегочное введение флуорохинолона - Google Patents

Внутрилегочное введение флуорохинолона Download PDF

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Publication number
RU2497524C2
RU2497524C2 RU2010150839/15A RU2010150839A RU2497524C2 RU 2497524 C2 RU2497524 C2 RU 2497524C2 RU 2010150839/15 A RU2010150839/15 A RU 2010150839/15A RU 2010150839 A RU2010150839 A RU 2010150839A RU 2497524 C2 RU2497524 C2 RU 2497524C2
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Russia
Prior art keywords
ciprofloxacin
powder
particles
betaine
composition
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RU2010150839/15A
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English (en)
Russian (ru)
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RU2010150839A (ru
Inventor
Джеффри ВИРС
Томас ТАРАРА
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Новартис Аг
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Publication of RU2497524C2 publication Critical patent/RU2497524C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0041Details of the piercing or cutting means with movable piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
RU2010150839/15A 2008-05-15 2009-05-15 Внутрилегочное введение флуорохинолона RU2497524C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12778008P 2008-05-15 2008-05-15
US61/127,780 2008-05-15
PCT/US2009/044116 WO2009140587A1 (en) 2008-05-15 2009-05-15 Pulmonary delivery of a fluoroquinolone

Publications (2)

Publication Number Publication Date
RU2010150839A RU2010150839A (ru) 2012-06-20
RU2497524C2 true RU2497524C2 (ru) 2013-11-10

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RU2010150839/15A RU2497524C2 (ru) 2008-05-15 2009-05-15 Внутрилегочное введение флуорохинолона

Country Status (11)

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US (3) US8834930B2 (https=)
EP (1) EP2285345A1 (https=)
JP (2) JP5727927B2 (https=)
KR (1) KR101621986B1 (https=)
CN (1) CN102099009B (https=)
AU (1) AU2009246217B2 (https=)
BR (1) BRPI0913021A2 (https=)
CA (1) CA2724009C (https=)
MX (1) MX2010012452A (https=)
RU (1) RU2497524C2 (https=)
WO (1) WO2009140587A1 (https=)

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2833847C1 (ru) * 2024-02-28 2025-01-29 Федеральное государственное бюджетное учреждение науки Оренбургский федеральный исследовательский центр Уральского отделения Российской академии наук Композиция на основе ципрофлоксацина и 7-гидроксикумарина, подавляющая систему чувства кворума LuxI/LuxR-типа у бактерий

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CA2724009A1 (en) 2009-11-19
JP2011520911A (ja) 2011-07-21
JP2015091829A (ja) 2015-05-14
BRPI0913021A2 (pt) 2015-10-13
RU2010150839A (ru) 2012-06-20
KR20110020816A (ko) 2011-03-03
US9155732B2 (en) 2015-10-13
MX2010012452A (es) 2011-03-15
CN102099009B (zh) 2014-07-02
WO2009140587A1 (en) 2009-11-19
US20140350028A1 (en) 2014-11-27
HK1155382A1 (en) 2012-05-18
CA2724009C (en) 2016-10-11
JP5989750B2 (ja) 2016-09-07
KR101621986B1 (ko) 2016-05-17
US20150374685A1 (en) 2015-12-31
AU2009246217A1 (en) 2009-11-19
US20110123626A1 (en) 2011-05-26
CN102099009A (zh) 2011-06-15
EP2285345A1 (en) 2011-02-23
JP5727927B2 (ja) 2015-06-03
AU2009246217B2 (en) 2013-01-10

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