JP2011519949A5 - - Google Patents

Download PDF

Info

Publication number
JP2011519949A5
JP2011519949A5 JP2011508634A JP2011508634A JP2011519949A5 JP 2011519949 A5 JP2011519949 A5 JP 2011519949A5 JP 2011508634 A JP2011508634 A JP 2011508634A JP 2011508634 A JP2011508634 A JP 2011508634A JP 2011519949 A5 JP2011519949 A5 JP 2011519949A5
Authority
JP
Japan
Prior art keywords
prg4
protein
eye
lens
ophthalmic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011508634A
Other languages
English (en)
Japanese (ja)
Other versions
JP5474054B2 (ja
JP2011519949A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/043018 external-priority patent/WO2009137603A1/en
Publication of JP2011519949A publication Critical patent/JP2011519949A/ja
Publication of JP2011519949A5 publication Critical patent/JP2011519949A5/ja
Application granted granted Critical
Publication of JP5474054B2 publication Critical patent/JP5474054B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011508634A 2008-05-07 2009-05-06 眼の境界潤滑を増加させるための、眼科治療の装置、及び、その使用方法、 Active JP5474054B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5111208P 2008-05-07 2008-05-07
US61/051,112 2008-05-07
PCT/US2009/043018 WO2009137603A1 (en) 2008-05-07 2009-05-06 Ophthalmic device, and method of use thereof, for increasing ocular boundary lubrication

Publications (3)

Publication Number Publication Date
JP2011519949A JP2011519949A (ja) 2011-07-14
JP2011519949A5 true JP2011519949A5 (https=) 2013-08-01
JP5474054B2 JP5474054B2 (ja) 2014-04-16

Family

ID=41264988

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2011508534A Active JP5508398B2 (ja) 2008-05-07 2009-04-08 眼の表面潤滑の治療的補充及び強化
JP2011508634A Active JP5474054B2 (ja) 2008-05-07 2009-05-06 眼の境界潤滑を増加させるための、眼科治療の装置、及び、その使用方法、
JP2011508633A Active JP5439652B2 (ja) 2008-05-07 2009-05-06 眼の表面の潤滑性の治療的調節

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2011508534A Active JP5508398B2 (ja) 2008-05-07 2009-04-08 眼の表面潤滑の治療的補充及び強化

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011508633A Active JP5439652B2 (ja) 2008-05-07 2009-05-06 眼の表面の潤滑性の治療的調節

Country Status (16)

Country Link
US (9) US8563028B2 (https=)
EP (4) EP2915529B1 (https=)
JP (3) JP5508398B2 (https=)
CN (2) CN105664136A (https=)
CA (3) CA2722913C (https=)
CY (2) CY1119122T1 (https=)
DK (3) DK2915529T3 (https=)
ES (3) ES2633792T3 (https=)
HR (3) HRP20150097T1 (https=)
HU (2) HUE024146T2 (https=)
LT (2) LT2915529T (https=)
PL (3) PL2915529T3 (https=)
PT (2) PT2285364E (https=)
RU (1) RU2510274C2 (https=)
SI (3) SI2915529T1 (https=)
WO (3) WO2009137217A2 (https=)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040082509A1 (en) 1999-10-12 2004-04-29 Christophe Bonny Cell-permeable peptide inhibitors of the JNK signal transduction pathway
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US7981095B2 (en) * 2005-07-18 2011-07-19 Tearscience, Inc. Methods for treating meibomian gland dysfunction employing fluid jet
US8950405B2 (en) 2006-05-15 2015-02-10 Tearscience, Inc. Treatment of obstructive disorders of the eye or eyelid
US20090043365A1 (en) * 2005-07-18 2009-02-12 Kolis Scientific, Inc. Methods, apparatuses, and systems for reducing intraocular pressure as a means of preventing or treating open-angle glaucoma
WO2013003594A2 (en) 2011-06-28 2013-01-03 Tearscience, Inc. Methods and systems for treating meibomian gland dysfunction using radio-frequency energy
US20080114423A1 (en) 2006-05-15 2008-05-15 Grenon Stephen M Apparatus for inner eyelid treatment of meibomian gland dysfunction
US7981145B2 (en) 2005-07-18 2011-07-19 Tearscience Inc. Treatment of meibomian glands
US8083787B2 (en) 2005-07-18 2011-12-27 Tearscience, Inc. Method and apparatus for treating meibomian gland dysfunction
US20070060988A1 (en) 2005-07-18 2007-03-15 Grenon Stephen M Melting meibomian gland obstructions
US7981146B2 (en) 2006-05-15 2011-07-19 Tearscience Inc. Inner eyelid treatment for treating meibomian gland dysfunction
WO2007031098A1 (en) 2005-09-12 2007-03-22 Xigen S.A. Cell-permeable peptide inhibitors of the jnk signal transduction pathway
US7976573B2 (en) 2006-05-15 2011-07-12 Tearscience, Inc. Inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
US8137390B2 (en) 2006-05-15 2012-03-20 Tearscience, Inc. System for providing heat treatment and heat loss reduction for treating meibomian gland dysfunction
US8128673B2 (en) 2006-05-15 2012-03-06 Tearscience, Inc. System for inner eyelid heat and pressure treatment for treating meibomian gland dysfunction
US7981147B2 (en) 2006-05-15 2011-07-19 Tearscience, Inc. Outer eyelid heat and pressure treatment for treating meibomian gland dysfunction
US9314369B2 (en) 2006-05-15 2016-04-19 Tearscience, Inc. System for inner eyelid treatment of meibomian gland dysfunction
US8007524B2 (en) 2006-05-15 2011-08-30 Tearscience, Inc. Heat treatment and heat loss reduction for treating meibomian gland dysfunction
US8128674B2 (en) 2006-05-15 2012-03-06 Tearscience, Inc. System for outer eyelid heat and pressure treatment for treating meibomian gland dysfunction
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
HUE024146T2 (en) * 2008-05-07 2016-02-29 Univ California Medical filling and enrichment of eye surface lubrication
US8506944B2 (en) * 2008-05-07 2013-08-13 The Regents Of The University Of California Replenishment and enrichment of ocular surface lubrication
WO2009143865A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
WO2009143864A1 (en) 2008-05-30 2009-12-03 Xigen S.A. Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases
WO2010072228A1 (en) 2008-12-22 2010-07-01 Xigen S.A. Novel transporter constructs and transporter cargo conjugate molecules
CA2762989C (en) 2009-05-22 2021-04-13 Benjamin Sullivan Prg4 for treatment of oral cavity boundary lubrication disorders
CN103002737A (zh) * 2010-01-11 2013-03-27 Gtx公司 治疗睑板腺功能障碍的方法
WO2011160653A1 (en) 2010-06-21 2011-12-29 Xigen S.A. Novel jnk inhibitor molecules
AU2010362444B2 (en) 2010-10-14 2015-08-06 Xigen Inflammation Ltd. Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases
WO2012174123A1 (en) * 2011-06-13 2012-12-20 Allergan, Inc. Treatment of psychological trauma
JP2014522849A (ja) * 2011-06-29 2014-09-08 アラーガン インコーポレイテッド ヒドロキシステアリン酸マクロゴール１５製剤
US20130029919A1 (en) * 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
MX2014006399A (es) * 2011-11-30 2015-04-10 Xigen Inflammation Ltd Uso de inhibidores de peptidos con celulas permeables de la via para transduccion de señal de jnk para el tratamiento de la queratoconjuntivitis seca.
WO2013091670A1 (en) 2011-12-21 2013-06-27 Xigen S.A. Novel jnk inhibitor molecules for treatment of various diseases
US9827250B2 (en) * 2012-07-31 2017-11-28 Johnson & Johnson Vision Care, Inc. Lens incorporating myopia control optics and muscarinic agents
US10842670B2 (en) 2012-08-22 2020-11-24 Johnson & Johnson Vision Care, Inc. Apparatuses and methods for diagnosing and/or treating lipid transport deficiency in ocular tear films, and related components and devices
US9763827B2 (en) 2013-04-30 2017-09-19 Tear Film Innovations, Inc. Systems and methods for the treatment of eye conditions
ES2821002T3 (es) 2013-04-30 2021-04-23 Alcon Inc Sistemas para el tratamiento de enfermedades del ojo
WO2015197097A1 (en) 2014-06-26 2015-12-30 Xigen Inflammation Ltd. New use for jnk inhibitor molecules for treatment of various diseases
WO2014206427A1 (en) 2013-06-26 2014-12-31 Xigen Inflammation Ltd. New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases
ES2870085T3 (es) 2013-06-26 2021-10-26 Xigen Inflammation Ltd Inhibidores peptídicos permeables a células de la ruta de transducción de señales de JNK para el tratamiento de la cistitis
WO2015060935A1 (en) 2013-10-22 2015-04-30 Lubris, Llc Control of rheological properties of mixed hyaluronate/lubricin solutions
US9668916B2 (en) 2013-11-04 2017-06-06 Vance M. Thompson Conjunctival cover and methods therefor
US20150141328A1 (en) * 2013-11-18 2015-05-21 The Schepens Eye Research Institute Stimulation of human meibomian gland function
EP3074022B1 (en) 2013-11-26 2022-03-30 Lubris LLC Compositions and methods for inhibiting intercellular interactions
US10940111B2 (en) 2014-06-15 2021-03-09 Yeda Research And Development Co. Ltd. Surface treatment by water-soluble polymers and lipids/liposomes
IL234929B (en) * 2014-10-01 2021-01-31 Yeda Res & Dev Liposomes-containing antifouling compositions and uses thereof
US9395557B2 (en) 2014-11-12 2016-07-19 Vance M. Thompson Partial corneal conjunctival contact lens
RU2017129880A (ru) 2015-01-26 2019-03-04 ЛУБРИС ЭлЭлСи Применение prg4 в качестве противовоспалительного средства
US9869883B2 (en) 2015-03-11 2018-01-16 Vance M. Thompson Tear shaping for refractive correction
WO2016159350A1 (ja) * 2015-04-03 2016-10-06 参天製薬株式会社 ナンドロロンまたはそのエステル、メテノロンまたはそのエステルを有効成分とするドライアイ治療剤
MA42148A (fr) * 2015-05-19 2018-04-04 Lubris Llc Utilisation de prg4 pour améliorer l'acuité visuelle dynamique et les aberrations d'ordre supérieur
JP6718608B2 (ja) * 2016-05-25 2020-07-08 国立大学法人愛媛大学 眼表面・眼瞼摩擦係数測定装置および眼表面・眼瞼摩擦係数評価方法
US10974063B2 (en) 2016-06-30 2021-04-13 Alcon Inc. Light therapy for eyelash growth
US10353220B2 (en) 2016-10-17 2019-07-16 Vance M. Thompson Tear shaping for refractive correction
US10678067B2 (en) 2018-04-06 2020-06-09 Vance M. Thompson Tear shaping for refractive correction
BR112020025148A2 (pt) * 2018-06-21 2021-03-09 Lubris Llc Lubricina para uso na cicatrização de feridas
WO2020097345A1 (en) * 2018-11-08 2020-05-14 The Schepens Eye Research Institute, Inc. Therapeutic approaches for tissue reconstruction and wound healing treatment
JP7224001B2 (ja) 2018-12-21 2023-02-17 国立大学法人京都大学 ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物
CN113573724B (zh) * 2019-01-15 2025-12-19 康奈尔大学 重组润滑素和组合物以及其使用方法
US20220273844A1 (en) * 2019-07-26 2022-09-01 Pandorum Technologies Private Limited Bio-ink formulations, bio-printed corneal lenticule, and applications thereof
WO2021067823A2 (en) * 2019-10-05 2021-04-08 The Schepens Eye Research Institute, Inc. A new treatment for meibomian gland dysfunction
US11609438B2 (en) * 2019-10-31 2023-03-21 Menicon Singapore Pte Ltd. Ocular lens with friction control structures

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
SE8501723L (sv) * 1985-04-09 1986-10-10 Pharmacia Ab Preparation att anvendas vid behandling av ledinflammation
US4964206A (en) * 1988-03-15 1990-10-23 Minnesota Mining And Manufacturing Company Intraocular lens anchoring filament to lens element fixation method
US4964205A (en) * 1988-06-13 1990-10-23 Rampart Packaging Inc. Method for making screw cap jar
US5326558A (en) 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
US6433142B1 (en) 1989-08-08 2002-08-13 Genetics Institute, Llc Megakaryocyte stimulating factors
RU2033165C1 (ru) * 1989-10-13 1995-04-20 Межотраслевой научно-технический комплекс "Микрохирургия глаза" Способ получения пластичного материала из коллагена
CA2133966C (en) * 1992-04-21 1997-09-09 David A. Sullivan Ocular androgen therapy in sjogren's syndrome
US6107289A (en) * 1992-04-21 2000-08-22 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens or TGF-β
US5688765A (en) * 1992-04-21 1997-11-18 The Schepens Eye Research Institute, Inc. Ocular therapy in Sjogren's syndrome using topically applied androgensor TGF-β
IL106922A (en) * 1992-09-14 1998-08-16 Novartis Ag Composite materials with one or more wettable surfaces and process for their preparation
US5351100A (en) * 1992-12-09 1994-09-27 Bmc Industries, Inc. Glass multifocal ophthalmic lens with polarizing element and method of making
JPH09505057A (ja) * 1993-11-19 1997-05-20 ザ・ユニバーシティ・オブ・シドニー 白内障を予防または制御するための方法
US5515590A (en) * 1994-07-19 1996-05-14 University Of Kentucky Research Foundation Method for reducing the generation of wear particulates from an implant
US5518732A (en) * 1995-02-14 1996-05-21 Chiron Vision, Inc. Bio-erodible ophthalmic shield
DE69629230D1 (de) * 1995-03-24 2003-09-04 Ocular Res Of Bonton Inc Hydrogellinse mit Lipid-Vorbeschichtigung
RU2207885C2 (ru) * 1995-08-30 2003-07-10 Фармация Аб Способ подачи небольшого объема лечебного раствора к целевому месту
US6689748B1 (en) * 1998-04-08 2004-02-10 Theoharis C. Theoharides Method of treating mast cell activation-induced diseases with a proteoglycan
WO2000027421A2 (en) * 1998-11-06 2000-05-18 The Schepens Eye Research Institute, Inc. LOCAL USE OF SOLUBLE TUMOR NECROSIS RECEPTOR I (sTNFRI) FOR PROPHYLAXIS AND TREATMENT OF CORNEAL TRANSPLANT REJECTION AND OTHER DISORDERS OF THE EYE
AU774977B2 (en) * 1998-11-10 2004-07-15 Denki Kagaku Kogyo Kabushiki Kaisha Hyaluronic acid gel, process for the preparation thereof and medical materials containing the same
US6743774B1 (en) 1999-04-23 2004-06-01 Rhode Island Hospital Tribonectins
US6960562B2 (en) 1999-04-23 2005-11-01 Rhode Island Hospital, A Lifespan Partner Tribonectin polypeptides and uses thereof
JP4755795B2 (ja) * 2000-02-03 2011-08-24 電気化学工業株式会社 ヒアルロン酸ゲルの製造方法及びそれを含有する医用材料
US6989156B2 (en) * 2001-04-23 2006-01-24 Nucryst Pharmaceuticals Corp. Therapeutic treatments using the direct application of antimicrobial metal compositions
US7026500B2 (en) 2000-08-24 2006-04-11 University Of Tennessee Research Foundation Halogenated selective androgen receptor modulators and methods of use thereof
JP2005502581A (ja) * 2000-12-20 2005-01-27 アルコン、インコーポレイテッド 改良された流動特性を有する眼内潅流溶液
AU2002232437A1 (en) * 2000-12-20 2002-07-01 Alcon Universal Ltd. Ophthalmic lubricating solution adapted for use in lasik surgery
US6815074B2 (en) * 2001-05-30 2004-11-09 Novartis Ag Polymeric materials for making contact lenses
CN1980582B (zh) * 2001-08-17 2010-12-22 美你康株式会社 用于用后即弃式软隐形眼镜的包装
US20030134810A1 (en) 2001-10-09 2003-07-17 Chris Springate Methods and compositions comprising biocompatible materials useful for the administration of therapeutic agents
AR038269A1 (es) * 2002-01-09 2005-01-12 Novartis Ag Articulos polimericos que tienen un recubrimiento lubrico, y metodo para fabricarlos
AR038926A1 (es) * 2002-03-13 2005-02-02 Novartis Ag Materiales con contenido de multiples capas de vesiculas
SE0201479D0 (sv) 2002-05-16 2002-05-16 Pharmacia Groningen Bv Kit and method in eye surgery
US20050196370A1 (en) * 2003-03-18 2005-09-08 Zhi-Jian Yu Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
US20050074497A1 (en) 2003-04-09 2005-04-07 Schultz Clyde L. Hydrogels used to deliver medicaments to the eye for the treatment of posterior segment diseases
WO2005013939A1 (en) 2003-08-06 2005-02-17 Nirmal Mulye Pharmaceutical composition containing water soluble drug
DK1663291T3 (da) * 2003-08-14 2012-07-02 Wyeth Llc Rekombinante lubricinmolekyler og anvendelser deraf
US7087237B2 (en) * 2003-09-19 2006-08-08 Advanced Ocular Systems Limited Ocular solutions
WO2005027933A1 (en) * 2003-09-23 2005-03-31 The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland Unsaturated phosphatidylcholines and uses thereof
CA2558497A1 (en) * 2004-03-05 2005-09-15 Synthes (U.S.A.) Use of a mixture for the production of an agent for treating defective or degenerated cartilage in the production of natural cartilage replacement in vitro
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
US20050287223A1 (en) * 2004-06-23 2005-12-29 Peyman Gholam A Use of amniotic membrane as biocompatible devices
EP1768687A2 (en) * 2004-06-29 2007-04-04 Massachusetts Institute Of Technology Methods and compositions related to the modulation of intercellular junctions
EP1778360A2 (en) * 2004-07-23 2007-05-02 Mucosal Therapeutics LLC Compositions and methods for viscosupplementation
US7662509B2 (en) * 2004-10-29 2010-02-16 Medtronic, Inc. Lithium-ion battery
US20060210645A1 (en) * 2005-03-02 2006-09-21 Du Mee Charles P Pharmaceutically acceptable carrier for ophthalmic compositions
DK2444079T3 (en) 2005-05-17 2017-01-30 Sarcode Bioscience Inc Compositions and Methods for the Treatment of Eye Diseases
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
JP5549045B2 (ja) * 2006-01-13 2014-07-16 大正製薬株式会社 蒸発亢進型ドライアイの予防又は改善用水性点眼剤
US20080094573A1 (en) * 2006-04-04 2008-04-24 Vermette Patrick Surface-modified materials, such as contact lenses, methods and kits for their preparation, and uses thereof
US9539202B2 (en) * 2006-04-28 2017-01-10 Universidad Complutense De Madrid Formulation of liposomal vesicles in aqueous solutions with lachrymal film characteristics
US20070264226A1 (en) * 2006-05-10 2007-11-15 Karagoezian Hampar L Synergistically enhanced disinfecting solutions
CN101528214B (zh) * 2006-08-24 2013-06-05 田纳西大学研究基金会 取代的n-酰基苯胺及其使用方法
US20080097606A1 (en) * 2006-10-19 2008-04-24 Cragg Andrew H Knee joint prosthesis and hyaluronate compositions for treatment of osteoarthritis
US20080197324A1 (en) * 2007-02-20 2008-08-21 Fang Zhao Ophthalmic composition containing a polyol-acid copolymer
US20090068247A1 (en) * 2007-09-12 2009-03-12 Mucosal Therapeutics Biocompatible devices coated with a tribonectin and methods for their production
EP2238480B1 (en) 2007-12-20 2012-02-01 Novartis AG Method for making contact lenses
HUE024146T2 (en) 2008-05-07 2016-02-29 Univ California Medical filling and enrichment of eye surface lubrication
US8506944B2 (en) * 2008-05-07 2013-08-13 The Regents Of The University Of California Replenishment and enrichment of ocular surface lubrication

Similar Documents

Publication Publication Date Title
JP2011519949A5 (https=)
JP5474054B2 (ja) 眼の境界潤滑を増加させるための、眼科治療の装置、及び、その使用方法、
US8506944B2 (en) Replenishment and enrichment of ocular surface lubrication
EP3347034B1 (en) A hepatocyte growth factor receptor (hgfr)-binding composition for use in a method of treating corneal haze or scarring
EP3096777B1 (en) Goblet cell replacement therapy
US20210169990A9 (en) Compostions for Treating Dry Eye Disease