JP2011516572A5 - - Google Patents
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- Publication number
- JP2011516572A5 JP2011516572A5 JP2011504178A JP2011504178A JP2011516572A5 JP 2011516572 A5 JP2011516572 A5 JP 2011516572A5 JP 2011504178 A JP2011504178 A JP 2011504178A JP 2011504178 A JP2011504178 A JP 2011504178A JP 2011516572 A5 JP2011516572 A5 JP 2011516572A5
- Authority
- JP
- Japan
- Prior art keywords
- oxygen atom
- group
- represent
- atom
- acyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000004430 oxygen atom Chemical group O* 0.000 claims 10
- 150000001875 compounds Chemical class 0.000 claims 7
- 125000002252 acyl group Chemical group 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 5
- 210000004027 cell Anatomy 0.000 claims 4
- 229910052717 sulfur Inorganic materials 0.000 claims 4
- 125000004434 sulfur atom Chemical group 0.000 claims 4
- 239000000126 substance Substances 0.000 claims 3
- 102000007469 Actins Human genes 0.000 claims 2
- 108010085238 Actins Proteins 0.000 claims 2
- 125000006539 C12 alkyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 2
- 230000008707 rearrangement Effects 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000003436 cytoskeletal effect Effects 0.000 claims 1
- 210000004292 cytoskeleton Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4358608P | 2008-04-09 | 2008-04-09 | |
| US61/043,586 | 2008-04-09 | ||
| PCT/US2009/040098 WO2009126822A2 (en) | 2008-04-09 | 2009-04-09 | Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011516572A JP2011516572A (ja) | 2011-05-26 |
| JP2011516572A5 true JP2011516572A5 (enExample) | 2012-05-24 |
| JP5562939B2 JP5562939B2 (ja) | 2014-07-30 |
Family
ID=41162617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011504178A Expired - Fee Related JP5562939B2 (ja) | 2008-04-09 | 2009-04-09 | アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8809303B2 (enExample) |
| EP (1) | EP2268286B1 (enExample) |
| JP (1) | JP5562939B2 (enExample) |
| KR (1) | KR20100135886A (enExample) |
| CN (1) | CN102083443B (enExample) |
| AU (1) | AU2009234156A1 (enExample) |
| BR (1) | BRPI0911195A2 (enExample) |
| CA (1) | CA2721082A1 (enExample) |
| EA (1) | EA201001450A1 (enExample) |
| ES (1) | ES2569608T3 (enExample) |
| IL (1) | IL208565A0 (enExample) |
| MX (1) | MX2010011050A (enExample) |
| WO (1) | WO2009126822A2 (enExample) |
| ZA (1) | ZA201007735B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5562939B2 (ja) | 2008-04-09 | 2014-07-30 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法 |
| EA201101349A1 (ru) * | 2009-04-09 | 2012-05-30 | Университет Северной Каролины В Чапел-Хилл | Методы лечения отека, связанного с ишемией-реперфузией |
| CN103160570A (zh) * | 2011-12-09 | 2013-06-19 | 彩虹天健康科技研究(北京)有限责任公司 | Unc-51激酶和pp1磷酸酶相互作用机制的发现 |
| EP3752182B1 (en) * | 2018-02-12 | 2024-05-15 | Inimmune Corporation | Toll-like receptor ligands |
| CN108836971B (zh) * | 2018-08-16 | 2020-10-30 | 青岛大学 | Ws6对小梁网细胞肌动蛋白形成的影响 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5628984A (en) | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
| US5843024A (en) | 1996-05-17 | 1998-12-01 | Breonics, Inc. | Solution and process for resuscitation and preparation of ischemically damaged tissue |
| US6113918A (en) | 1997-05-08 | 2000-09-05 | Ribi Immunochem Research, Inc. | Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors |
| US6013640A (en) * | 1998-08-21 | 2000-01-11 | Ribi Immunochem Research, Inc. | Phosphoglycolipid and methods for its use |
| PT1252293E (pt) * | 2000-01-19 | 2013-01-23 | Univ North Carolina | Fonte de tecido de fígado |
| US6699846B2 (en) | 2000-03-17 | 2004-03-02 | Corixa Corporation | Mono- and disaccharides for the treatment of nitric oxide related disorders |
| WO2003105909A1 (ja) * | 2002-06-13 | 2003-12-24 | 三菱ウェルファーマ株式会社 | 肝虚血再灌流傷害の予防及び/又は治療のための医薬並びに移植肝臓の保護剤 |
| US7960522B2 (en) | 2003-01-06 | 2011-06-14 | Corixa Corporation | Certain aminoalkyl glucosaminide phosphate compounds and their use |
| JP2007514648A (ja) | 2003-10-24 | 2007-06-07 | エーザイ株式会社 | Toll−likereceptor2に関連する疾患及び状態を治療するための化合物及び方法 |
| US7928132B2 (en) | 2004-08-06 | 2011-04-19 | Ohio University | Methods for the amelioration of episodes of acute or chronic ulcerative colitis |
| US20060211752A1 (en) | 2004-03-16 | 2006-09-21 | Kohn Leonard D | Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression |
| JP2007534775A (ja) * | 2004-05-28 | 2007-11-29 | セダーズ−シナイ メディカル センター | 脈管の疾患を処置するための方法 |
| ITMI20060530A1 (it) * | 2006-03-22 | 2007-09-23 | Univ Milano Bicocca | Antinfiammatori a struttura monosaccaridica |
| EP2170366B1 (en) | 2007-08-03 | 2013-11-06 | Opsona Therapeutics Limited | Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage |
| JP5562939B2 (ja) | 2008-04-09 | 2014-07-30 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法 |
| EA201101349A1 (ru) | 2009-04-09 | 2012-05-30 | Университет Северной Каролины В Чапел-Хилл | Методы лечения отека, связанного с ишемией-реперфузией |
-
2009
- 2009-04-09 JP JP2011504178A patent/JP5562939B2/ja not_active Expired - Fee Related
- 2009-04-09 EA EA201001450A patent/EA201001450A1/ru unknown
- 2009-04-09 ES ES09730162.6T patent/ES2569608T3/es active Active
- 2009-04-09 KR KR1020107024897A patent/KR20100135886A/ko not_active Withdrawn
- 2009-04-09 AU AU2009234156A patent/AU2009234156A1/en not_active Abandoned
- 2009-04-09 WO PCT/US2009/040098 patent/WO2009126822A2/en not_active Ceased
- 2009-04-09 CN CN200980121482.3A patent/CN102083443B/zh not_active Expired - Fee Related
- 2009-04-09 US US12/936,801 patent/US8809303B2/en not_active Expired - Fee Related
- 2009-04-09 EP EP09730162.6A patent/EP2268286B1/en active Active
- 2009-04-09 BR BRPI0911195A patent/BRPI0911195A2/pt not_active IP Right Cessation
- 2009-04-09 CA CA2721082A patent/CA2721082A1/en not_active Abandoned
- 2009-04-09 MX MX2010011050A patent/MX2010011050A/es active IP Right Grant
-
2010
- 2010-10-07 IL IL208565A patent/IL208565A0/en unknown
- 2010-10-28 ZA ZA2010/07735A patent/ZA201007735B/en unknown
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