EA201101349A1 - Методы лечения отека, связанного с ишемией-реперфузией - Google Patents

Методы лечения отека, связанного с ишемией-реперфузией

Info

Publication number
EA201101349A1
EA201101349A1 EA201101349A EA201101349A EA201101349A1 EA 201101349 A1 EA201101349 A1 EA 201101349A1 EA 201101349 A EA201101349 A EA 201101349A EA 201101349 A EA201101349 A EA 201101349A EA 201101349 A1 EA201101349 A1 EA 201101349A1
Authority
EA
Eurasian Patent Office
Prior art keywords
reperfusion
ischemia
treatment methods
domestic associated
domestic
Prior art date
Application number
EA201101349A
Other languages
English (en)
Inventor
Томас Майкл Эган
Original Assignee
Университет Северной Каролины В Чапел-Хилл
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Университет Северной Каролины В Чапел-Хилл filed Critical Университет Северной Каролины В Чапел-Хилл
Publication of EA201101349A1 publication Critical patent/EA201101349A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Описаны методы предотвращения или уменьшения отека, связанного с ишемией-реперфузией, путем обработки трансплантируемого органа или ткани аминоалкил глюкозаминид фосфатом .
EA201101349A 2009-04-09 2010-04-09 Методы лечения отека, связанного с ишемией-реперфузией EA201101349A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16808909P 2009-04-09 2009-04-09
PCT/US2010/030556 WO2010118334A1 (en) 2009-04-09 2010-04-09 Methods of treating edema related to ischemia-reperfusion

Publications (1)

Publication Number Publication Date
EA201101349A1 true EA201101349A1 (ru) 2012-05-30

Family

ID=42936599

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201101349A EA201101349A1 (ru) 2009-04-09 2010-04-09 Методы лечения отека, связанного с ишемией-реперфузией

Country Status (14)

Country Link
US (1) US20120064044A1 (ru)
EP (1) EP2416651A4 (ru)
JP (1) JP2012523432A (ru)
KR (1) KR20120005025A (ru)
CN (1) CN102458113A (ru)
AU (1) AU2010233151A1 (ru)
BR (1) BRPI1010516A2 (ru)
CA (1) CA2757998A1 (ru)
EA (1) EA201101349A1 (ru)
IL (1) IL215604A0 (ru)
MX (1) MX2011010616A (ru)
SG (1) SG175133A1 (ru)
WO (1) WO2010118334A1 (ru)
ZA (1) ZA201107815B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0911195A2 (pt) * 2008-04-09 2017-06-20 The Univ Of North Caroline At Chapel Hill métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular
JP6000287B2 (ja) * 2011-03-03 2016-09-28 クォーク ファーマシューティカルズ インコーポレーティッドＱｕａｒｋ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 肺疾患および損傷を治療するための組成物および方法
WO2013082458A1 (en) 2011-12-02 2013-06-06 The Regents Of The University Of California Reperfusion protection solution and uses thereof
JP7330893B2 (ja) 2017-03-10 2023-08-22 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 短時間作用型ヘパリンベースの抗凝集剤化合物及び方法
US11993627B2 (en) 2017-07-03 2024-05-28 The University Of North Carolina At Chapel Hill Enzymatic synthesis of homogeneous chondroitin sulfate oligosaccharides
US11865137B2 (en) 2017-11-03 2024-01-09 The University Of North Carolina At Chapel Hill Sulfated oligosaccharides having anti-inflammatory activity
JP7362667B2 (ja) 2018-02-12 2023-10-17 イニミューン・コーポレーション Ｔｏｌｌ様受容体リガンド
CN112437667B (zh) 2018-06-20 2024-05-28 北卡罗来纳大学查珀尔希尔分校 细胞保护方法和组合物
JP2023501568A (ja) * 2019-11-13 2023-01-18 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 肝虚血再灌流障害におけるヘパラン硫酸（ｈｓ）オリゴ糖の効果

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05139992A (ja) * 1991-11-13 1993-06-08 Ajinomoto Co Inc ヒトａｄｆを含有する臓器保護剤
US6113918A (en) * 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US7960522B2 (en) * 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
JPWO2004085396A1 (ja) * 2003-03-26 2006-06-29 三菱ウェルファーマ株式会社 虚血再灌流障害の予防または治療剤、臓器保存剤およびスクリーニング方法
US7928132B2 (en) * 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
US20060211752A1 (en) * 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
JP5576275B2 (ja) * 2007-08-03 2014-08-20 オプソナ セラピューティクス リミテッド 再灌流障害および組織損傷を処置するためのｔｌｒ−２拮抗薬の使用
BRPI0911195A2 (pt) * 2008-04-09 2017-06-20 The Univ Of North Caroline At Chapel Hill métodos de regulação de arranjo de citoesqueleto de actina e formação de gap intracelular

Also Published As

Publication number Publication date
EP2416651A1 (en) 2012-02-15
CN102458113A (zh) 2012-05-16
SG175133A1 (en) 2011-12-29
AU2010233151A1 (en) 2011-11-17
JP2012523432A (ja) 2012-10-04
EP2416651A4 (en) 2014-03-26
US20120064044A1 (en) 2012-03-15
MX2011010616A (es) 2012-03-14
ZA201107815B (en) 2013-04-24
BRPI1010516A2 (pt) 2015-08-25
IL215604A0 (en) 2011-12-29
WO2010118334A1 (en) 2010-10-14
CA2757998A1 (en) 2010-10-14
KR20120005025A (ko) 2012-01-13

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