JP2014517008A5 - - Google Patents

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JP2014517008A5
JP2014517008A5 JP2014514596A JP2014514596A JP2014517008A5 JP 2014517008 A5 JP2014517008 A5 JP 2014517008A5 JP 2014514596 A JP2014514596 A JP 2014514596A JP 2014514596 A JP2014514596 A JP 2014514596A JP 2014517008 A5 JP2014517008 A5 JP 2014517008A5
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use according
medicament
manufacture
muscle
animal
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JP2014514596A
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JP6001060B2 (ja
JP2014517008A (ja
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Priority claimed from PCT/US2012/041119 external-priority patent/WO2012170546A1/en
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JP2014514596A 2011-06-06 2012-06-06 筋萎縮を阻害するための方法 Active JP6001060B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161493969P 2011-06-06 2011-06-06
US61/493,969 2011-06-06
PCT/US2012/041119 WO2012170546A1 (en) 2011-06-06 2012-06-06 Methods of inhibiting muscle atrophy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016169533A Division JP6175172B2 (ja) 2011-06-06 2016-08-31 筋萎縮を阻害するための方法

Publications (3)

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JP2014517008A JP2014517008A (ja) 2014-07-17
JP2014517008A5 true JP2014517008A5 (enExample) 2015-07-30
JP6001060B2 JP6001060B2 (ja) 2016-10-05

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JP2014514596A Active JP6001060B2 (ja) 2011-06-06 2012-06-06 筋萎縮を阻害するための方法
JP2016169533A Active JP6175172B2 (ja) 2011-06-06 2016-08-31 筋萎縮を阻害するための方法
JP2017133423A Pending JP2017226670A (ja) 2011-06-06 2017-07-07 筋萎縮を阻害するための方法

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JP2016169533A Active JP6175172B2 (ja) 2011-06-06 2016-08-31 筋萎縮を阻害するための方法
JP2017133423A Pending JP2017226670A (ja) 2011-06-06 2017-07-07 筋萎縮を阻害するための方法

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US (3) US9295664B2 (enExample)
EP (2) EP2717876B1 (enExample)
JP (3) JP6001060B2 (enExample)
CN (2) CN106822153B (enExample)
AU (2) AU2012268036B2 (enExample)
CA (1) CA2838275C (enExample)
IL (2) IL229802A (enExample)
WO (1) WO2012170546A1 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012170546A1 (en) 2011-06-06 2012-12-13 University Of Iowa Research Foundation Methods of inhibiting muscle atrophy
US11090313B2 (en) * 2010-05-20 2021-08-17 University Of Iowa Research Foundation Methods for inhibiting muscle atrophy
WO2014022772A1 (en) * 2012-08-03 2014-02-06 University Of Iowa Research Foundation Tomatidine, analogs thereof, compositions comprising same, and uses for same
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US11419903B2 (en) 2015-11-30 2022-08-23 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US9730967B2 (en) 2011-02-04 2017-08-15 Katherine Rose Kovarik Method and system for treating cancer cachexia
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US10314865B2 (en) 2011-02-04 2019-06-11 Katherine Rose Kovarik Method and system for treating cancer and other age-related diseases by extending the healthspan of a human
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US10202356B2 (en) 2013-03-14 2019-02-12 Tolero Pharmaceuticals, Inc. JAK2 and ALK2 inhibitors and methods for their use
WO2015095449A1 (en) * 2013-12-19 2015-06-25 Ptc Therapeutics, Inc. Methods for modulating the amount rna transcripts
US11672835B2 (en) 2013-12-20 2023-06-13 Seed Health, Inc. Method for treating individuals having cancer and who are receiving cancer immunotherapy
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11529379B2 (en) 2013-12-20 2022-12-20 Seed Health, Inc. Method and system for reducing the likelihood of developing colorectal cancer in an individual human being
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US11026982B2 (en) 2015-11-30 2021-06-08 Joseph E. Kovarik Method for reducing the likelihood of developing bladder or colorectal cancer in an individual human being
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11642382B2 (en) 2013-12-20 2023-05-09 Seed Health, Inc. Method for treating an individual suffering from bladder cancer
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
US11213552B2 (en) 2015-11-30 2022-01-04 Joseph E. Kovarik Method for treating an individual suffering from a chronic infectious disease and cancer
CN105884852B (zh) * 2015-01-07 2019-07-05 中国药科大学 齐墩果酸与胆碱的共晶、其制备方法及其药物组合物
NL2015032B1 (en) 2015-06-26 2017-01-24 Vitalnext B V Compositions and methods for the treatment of malnutrition.
EP3368043B1 (en) * 2015-10-29 2021-12-01 Emmyon, Inc. Furostan-3-ol derivatives as skeletal muscle hypertrophic agents
CN107058557A (zh) * 2017-05-12 2017-08-18 安徽省农业科学院畜牧兽医研究所 影响猪肉质性状的功能候选基因及其筛选方法
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
WO2019055280A1 (en) 2017-09-13 2019-03-21 Emmyon, Inc. DIETHANOLAMINE SALTS AND URSOLIC ACID MORPHOLIN
PL3820573T3 (pl) 2018-07-10 2024-02-19 Novartis Ag Pochodne 3-(5-hydroksy-1-oksoizoindolin-2-ylo)piperydyno-2,6-dionu i ich zastosowanie w leczeniu chorób zależnych od palca cynkowego z rodziny ikaros 2 (ikzf2)
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
MX2021000977A (es) 2018-07-26 2021-04-12 Sumitomo Pharma Oncology Inc Metodos para tratar enfermedades asociadas con expresion anormal de receptor de activina a tipo 1 (acvr1) e inhibidores de acvr1 para uso en los mismos.
PL3883387T3 (pl) * 2018-11-20 2024-06-24 Nutreco Ip Assets B.V. Kompozycja do karmienia ciężarnego zwierzęcia
US10343997B1 (en) 2018-12-04 2019-07-09 King Saud University Ursolic acid derivatives
CN109632773B (zh) * 2019-01-08 2021-11-12 贵州大学 一种二氢硫辛酸琥珀酰转移酶抑制剂的筛选方法
EP3914282A1 (en) * 2019-01-25 2021-12-01 Ospedale San Raffaele S.r.l. Inhibitor of dux4 and uses thereof
CN111948401B (zh) * 2019-06-26 2022-04-15 浙江大学 CHCHD10在促进AChR亚基基因表达和维持NMJ稳定中的应用
AU2020334194A1 (en) * 2019-08-16 2022-02-24 Volker Adams Compounds suitable for the treatment and prophylaxis of muscle wasting and other conditions
AU2020374957A1 (en) * 2019-10-30 2022-04-28 Dana-Farber Cancer Institute, Inc. Small molecule degraders of Helios and methods of use
WO2021099503A1 (en) * 2019-11-19 2021-05-27 Nutreco Ip Assets B.V. Animal feed and methods for improving animal performance and productivity
JP7648129B2 (ja) * 2020-09-24 2025-03-18 国立大学法人金沢大学 うつ症状の予防、治療及び/又は緩和用組成物並びに運動量増加組成物
KR102802853B1 (ko) * 2021-02-26 2025-05-07 이엑스헬스케어 주식회사 피부 유래 엑소좀을 통해 근손실 억제 또는 근생성 촉진 효과를 나타내는 조성물
CN114622020B (zh) * 2022-03-30 2022-09-27 华南农业大学 一种与鸡生长性状相关的klhl31基因分子标记及应用
WO2024006287A2 (en) * 2022-06-27 2024-01-04 University Of Kansas Antiviral compounds useful against sars-cov-2
KR20240078995A (ko) * 2022-11-28 2024-06-04 재단법인 아산사회복지재단 근감소증 진단용 바이오마커 및 이를 이용한 근감소증 진단방법
WO2024243339A2 (en) * 2023-05-23 2024-11-28 Burrell Justin Boldine to reduce muscle atrophy and promote neuromuscular recovery

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2684365A (en) * 1952-02-07 1954-07-20 Mosettig Erich Method of converting tomatidine into delta16-allopregnenolone
US2770618A (en) * 1952-10-07 1956-11-13 American Home Prod Tomatidine derivatives
US2910470A (en) 1958-11-20 1959-10-27 Searle & Co 3-oxocona-1, 4-dienine and intermediates for its preparation
NL124636C (enExample) 1965-02-26
NL6509936A (enExample) 1965-07-30 1967-01-31
US3625941A (en) 1968-04-30 1971-12-07 Searle & Co ALPHA-(2-LOWER ALKYL-2-{8 2-(6-LKOXY OR TERTIARY AMINO-1,2,3,4-TETRAHYDRONAPHTH-1-YLIDEN) ethyl{9 -3-OXO CYCLO-PERET-1-YLIDENAMINOXY OR OXO HYDROZINO) ALKONIC ACID AND ASYMMETRIC FORCES FOR THEIR PRODUCTION
GB1414047A (en) 1973-03-15 1975-11-12 Biorex Laboratories Ltd Ursolic acid derivatives
NZ193564A (en) 1979-05-02 1985-01-31 Aruba Pty Ltd Steroid alkaloids from solanum sodomeum and pharmaceutical compositions
AU578068B2 (en) 1984-03-08 1988-10-13 Nippon Zoki Pharmaceutical Co., Ltd. Hydantoin derivatives and pharmaceutical compositions containing them
AT396589B (de) 1990-06-05 1993-10-25 Chemie Linz Gmbh Verfahren zur herstellung von allantoin
US5422350A (en) 1992-09-10 1995-06-06 Warner-Lambert Company Nitrogen substituted acridine and cytochrome P450 inhibitors and methods of use
BE1008235A5 (nl) * 1994-03-25 1996-02-20 Univ Gent Analysemethode geschikt om beta-agonisten en beta-antagonisten op te sporen.
BR9508110A (pt) 1994-06-24 1997-08-12 Nippon Shinyaku Co Ltd Derivado de triterpeno e composição médica
JP3041232B2 (ja) 1995-11-16 2000-05-15 日本ケミカルリサーチ株式会社 癌転移抑制剤
JP3069686B2 (ja) 1997-12-08 2000-07-24 農林水産省四国農業試験場長 フラバノン類含有組成物
EP1067939B1 (en) * 1998-04-09 2015-09-16 The Johns Hopkins University Use of steroidal alkaloid derivatives as inhibitors of hedgehog protein signaling pathways
KR20000019716A (ko) * 1998-09-15 2000-04-15 박호군 바이오플라보노이드 화합물을 포함하는 혈당 강하용 조성물
AUPP968699A0 (en) * 1999-04-09 1999-05-06 Cura Nominees Pty Ltd Therapeutic compositions and method for their preparation
IL133809A0 (en) * 1999-12-30 2001-04-30 Yeda Res & Dev Steroidal alkaloids and pharmaceutical compositions comprising them
CA2418117A1 (en) 2000-07-31 2003-01-30 The Nisshin Oillio, Ltd. Antitumor agent
US7708998B2 (en) 2000-10-13 2010-05-04 Curis, Inc. Methods of inhibiting unwanted cell proliferation using hedgehog antagonists
JP5196700B2 (ja) * 2000-10-13 2013-05-15 キュリス,インコーポレイテッド ヘッジホッグアンタゴニスト、それらに関する方法及び利用
WO2002043736A1 (en) 2000-11-30 2002-06-06 The Nisshin Oillio, Ltd. Beautifying foods and drinks and peroral beautifying preparations
JP3716975B2 (ja) 2001-10-30 2005-11-16 独立行政法人科学技術振興機構 新規ナリンゲニン誘導体及びその用途
CA2469340A1 (en) 2001-12-06 2003-06-19 Gtx Inc. Treating muscle wasting with selective androgen receptor modulators
US20030198684A1 (en) * 2002-04-23 2003-10-23 A. Braswell Composition and method for increasing testosterone levels
US20050090453A1 (en) * 2003-01-15 2005-04-28 Solbec Pharmaceuticals Co., Ltd. Methods of modulating IL-6
US7256208B2 (en) * 2003-11-13 2007-08-14 Bristol-Myers Squibb Company Monocyclic N-Aryl hydantoin modulators of androgen receptor function
CN100506092C (zh) * 2004-06-08 2009-07-01 千南成 中药解酒饮料
EP1618881A1 (en) 2004-07-20 2006-01-25 Santhera Pharmaceuticals (Schweiz) GmbH Use of non-glucocorticoid steroids for the treatment of muscular dystrophy
US7772195B2 (en) 2004-07-29 2010-08-10 Board Of Trustees Of Michigan State University Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia
WO2006031943A1 (en) 2004-09-14 2006-03-23 Eldridge Gary R Compounds, compositions and methods for controlling biofilms and bacterial infections
US20060062863A1 (en) * 2004-09-22 2006-03-23 Shibnath Ghosal Compositions for anti-obesity, health-restorative and health-promotional benefits
US20060083793A1 (en) * 2004-09-29 2006-04-20 Gardiner Paul T Nutritional composition for promoting muscle performance and acting as hydrogen (H+) blocker
CA2582231A1 (en) * 2004-09-29 2006-10-19 Hollis-Eden Pharmaceuticals, Inc. Steroid analogs and uses
US8143425B2 (en) * 2004-10-12 2012-03-27 Bristol-Myers Squibb Company Heterocyclic aromatic compounds useful as growth hormone secretagogues
WO2006132033A1 (ja) 2005-06-10 2006-12-14 Pola Chemical Industries Inc. 新規トリテルペン酸誘導体及びそれを含有してなる皮膚外用剤
US20080317885A1 (en) 2005-07-15 2008-12-25 Baker Donald J Compositions and Methods for Treating and Preventing Inflammatory and/or Degenerative Processes in Humans and Other Animals
WO2007053915A2 (en) 2005-11-09 2007-05-18 Universiteit Gent Naringenin derivatives with selectivity on ers
WO2007097289A1 (ja) 2006-02-20 2007-08-30 Takeda Pharmaceutical Company Limited 新規医薬
US8097596B2 (en) 2006-06-30 2012-01-17 Lakewood-Amedex, Inc. Compositions and methods for the treatment of muscle wasting
US20090203661A1 (en) 2006-10-12 2009-08-13 Safe Stephen H Betulinic acid, derivatives and analogs thereof and uses therefor
WO2008058269A2 (en) * 2006-11-09 2008-05-15 Foldrx Pharmaceuticals, Inc. Compounds and methods for modulating protein trafficking
WO2008115469A2 (en) 2007-03-16 2008-09-25 The Regents Of The University Of California Role of hedgehog signaling in atherosclerosis and cardiovascular disease
WO2008122038A1 (en) * 2007-04-02 2008-10-09 President And Fellows Of Harvard College Regulating autophagy
WO2008156654A2 (en) 2007-06-15 2008-12-24 Massachusetts Institute Of Technology Cytoskeleton modulators for treating metabolic disorders
WO2009082459A2 (en) * 2007-12-24 2009-07-02 Natrol, Inc. Anti-aging composition containing resveratrol and method of administration
JP2009209099A (ja) * 2008-03-05 2009-09-17 Kumamoto Univ 動脈硬化の予防・治療剤
US20100040568A1 (en) 2008-04-30 2010-02-18 Skinmedica, Inc. Steroidal compounds as melanogenesis modifiers and uses thereof
JP2010095459A (ja) 2008-10-15 2010-04-30 Kinki Univ 脂肪蓄積・代謝改善剤、抗TNF−α作用剤、及び新規トリテルペン化合物
US20100104669A1 (en) * 2008-10-28 2010-04-29 Scheffler Armin Method for preparing an aqueous solution containing triterpenic acid, aqueous solution containing triterpenic acid, and use thereof
US20120010176A1 (en) * 2008-11-12 2012-01-12 Khurana Tejvir S Utrophin promoter activity upregulation for the treatment of muscular dystrophy
US20100204121A1 (en) 2009-02-10 2010-08-12 Romero Augustin T Dietary supplements containing terpenoid acids of maslinic acid or oleanolic acid and process for enhancing muscle mass in mammals
EP2246050A1 (en) 2009-04-27 2010-11-03 IMR - International Medical Research - Partner GmbH Combination therapy comprising mechanical vibration for the treatment of a disease of the musculoskeletal or nervous system
WO2010132776A1 (en) * 2009-05-14 2010-11-18 Rutgers, The State University Of New Jersey Oregano and mint anti-inflammatory compositions and methods
RU2558534C2 (ru) * 2009-10-09 2015-08-10 Нестек С.А. Способы предупреждения или лечения саркопении и мышечной атрофии у животных
WO2011056549A1 (en) 2009-10-27 2011-05-12 Access Business Group International Llc Molecular targets and dietary modulators of exercise-induced muscle damage
AU2011255495A1 (en) 2010-05-20 2012-12-06 The United States Of America, As Represented By The Secretary Of The Department Of Veterans Affairs Methods for inhibiting muscle atrophy
WO2012170546A1 (en) 2011-06-06 2012-12-13 University Of Iowa Research Foundation Methods of inhibiting muscle atrophy
WO2014022772A1 (en) 2012-08-03 2014-02-06 University Of Iowa Research Foundation Tomatidine, analogs thereof, compositions comprising same, and uses for same
CN103038245B (zh) 2010-06-04 2015-03-25 百时美施贵宝公司 作为hiv成熟抑制剂的c-3经修饰的桦木酸衍生物
CN101940616B (zh) * 2010-08-31 2012-07-25 中国药科大学 一种防治糖尿病的风轮菜有效部位的制备方法与药物用途
RS20100392A3 (en) 2010-09-06 2012-12-31 Pavlov, Aleksandar Procedure for obtaining herbal preparation based on herbal mixture extract for application on skin and herbal preparation obtained thereof
LT2661266T (lt) 2011-01-07 2020-12-10 Anji Pharma (Us) Llc Gydimo būdai chemosensorinio receptoriaus ligando pagrindu

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