KR20100135886A - 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법 - Google Patents

액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법 Download PDF

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Publication number
KR20100135886A
KR20100135886A KR1020107024897A KR20107024897A KR20100135886A KR 20100135886 A KR20100135886 A KR 20100135886A KR 1020107024897 A KR1020107024897 A KR 1020107024897A KR 20107024897 A KR20107024897 A KR 20107024897A KR 20100135886 A KR20100135886 A KR 20100135886A
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South Korea
Prior art keywords
cell
cells
compound
cytoskeletal rearrangement
actin cytoskeletal
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KR1020107024897A
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English (en)
Korean (ko)
Inventor
토마스 마이클 이건
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더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐
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Publication of KR20100135886A publication Critical patent/KR20100135886A/ko
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020107024897A 2008-04-09 2009-04-09 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법 Withdrawn KR20100135886A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4358608P 2008-04-09 2008-04-09
US61/043,586 2008-04-09

Publications (1)

Publication Number Publication Date
KR20100135886A true KR20100135886A (ko) 2010-12-27

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ID=41162617

Family Applications (1)

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KR1020107024897A Withdrawn KR20100135886A (ko) 2008-04-09 2009-04-09 액틴 세포 골격의 재배열 및 세포간 갭 형성을 조절하는 방법

Country Status (14)

Country Link
US (1) US8809303B2 (enExample)
EP (1) EP2268286B1 (enExample)
JP (1) JP5562939B2 (enExample)
KR (1) KR20100135886A (enExample)
CN (1) CN102083443B (enExample)
AU (1) AU2009234156A1 (enExample)
BR (1) BRPI0911195A2 (enExample)
CA (1) CA2721082A1 (enExample)
EA (1) EA201001450A1 (enExample)
ES (1) ES2569608T3 (enExample)
IL (1) IL208565A0 (enExample)
MX (1) MX2010011050A (enExample)
WO (1) WO2009126822A2 (enExample)
ZA (1) ZA201007735B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5562939B2 (ja) 2008-04-09 2014-07-30 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法
EA201101349A1 (ru) * 2009-04-09 2012-05-30 Университет Северной Каролины В Чапел-Хилл Методы лечения отека, связанного с ишемией-реперфузией
CN103160570A (zh) * 2011-12-09 2013-06-19 彩虹天健康科技研究(北京)有限责任公司 Unc-51激酶和pp1磷酸酶相互作用机制的发现
EP3752182B1 (en) * 2018-02-12 2024-05-15 Inimmune Corporation Toll-like receptor ligands
CN108836971B (zh) * 2018-08-16 2020-10-30 青岛大学 Ws6对小梁网细胞肌动蛋白形成的影响

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6113918A (en) 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6013640A (en) * 1998-08-21 2000-01-11 Ribi Immunochem Research, Inc. Phosphoglycolipid and methods for its use
PT1252293E (pt) * 2000-01-19 2013-01-23 Univ North Carolina Fonte de tecido de fígado
US6699846B2 (en) 2000-03-17 2004-03-02 Corixa Corporation Mono- and disaccharides for the treatment of nitric oxide related disorders
WO2003105909A1 (ja) * 2002-06-13 2003-12-24 三菱ウェルファーマ株式会社 肝虚血再灌流傷害の予防及び/又は治療のための医薬並びに移植肝臓の保護剤
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
JP2007514648A (ja) 2003-10-24 2007-06-07 エーザイ株式会社 Toll−likereceptor2に関連する疾患及び状態を治療するための化合物及び方法
US7928132B2 (en) 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
JP2007534775A (ja) * 2004-05-28 2007-11-29 セダーズ−シナイ メディカル センター 脈管の疾患を処置するための方法
ITMI20060530A1 (it) * 2006-03-22 2007-09-23 Univ Milano Bicocca Antinfiammatori a struttura monosaccaridica
EP2170366B1 (en) 2007-08-03 2013-11-06 Opsona Therapeutics Limited Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
JP5562939B2 (ja) 2008-04-09 2014-07-30 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法
EA201101349A1 (ru) 2009-04-09 2012-05-30 Университет Северной Каролины В Чапел-Хилл Методы лечения отека, связанного с ишемией-реперфузией

Also Published As

Publication number Publication date
US8809303B2 (en) 2014-08-19
WO2009126822A2 (en) 2009-10-15
CN102083443A (zh) 2011-06-01
MX2010011050A (es) 2010-11-01
EP2268286A4 (en) 2011-10-12
JP5562939B2 (ja) 2014-07-30
US20110053871A1 (en) 2011-03-03
JP2011516572A (ja) 2011-05-26
AU2009234156A1 (en) 2009-10-15
EP2268286A1 (en) 2011-01-05
CA2721082A1 (en) 2009-10-15
WO2009126822A9 (en) 2009-12-17
IL208565A0 (en) 2010-12-30
ES2569608T3 (es) 2016-05-11
ZA201007735B (en) 2013-04-24
CN102083443B (zh) 2014-01-15
BRPI0911195A2 (pt) 2017-06-20
EP2268286B1 (en) 2016-04-06
EA201001450A1 (ru) 2011-08-30

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PA0105 International application

Patent event date: 20101105

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid