ZA201007735B - Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation - Google Patents

Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Info

Publication number
ZA201007735B
ZA201007735B ZA2010/07735A ZA201007735A ZA201007735B ZA 201007735 B ZA201007735 B ZA 201007735B ZA 2010/07735 A ZA2010/07735 A ZA 2010/07735A ZA 201007735 A ZA201007735 A ZA 201007735A ZA 201007735 B ZA201007735 B ZA 201007735B
Authority
ZA
South Africa
Prior art keywords
methods
gap formation
cytoskeletal rearrangement
actin cytoskeletal
intercellular gap
Prior art date
Application number
ZA2010/07735A
Other languages
English (en)
Inventor
Thomas Michael Egan
Original Assignee
Univ North Carolina Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina Chapel Hill filed Critical Univ North Carolina Chapel Hill
Publication of ZA201007735B publication Critical patent/ZA201007735B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2010/07735A 2008-04-09 2010-10-28 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation ZA201007735B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4358608P 2008-04-09 2008-04-09
PCT/US2009/040098 WO2009126822A2 (en) 2008-04-09 2009-04-09 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Publications (1)

Publication Number Publication Date
ZA201007735B true ZA201007735B (en) 2013-04-24

Family

ID=41162617

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/07735A ZA201007735B (en) 2008-04-09 2010-10-28 Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation

Country Status (14)

Country Link
US (1) US8809303B2 (enExample)
EP (1) EP2268286B1 (enExample)
JP (1) JP5562939B2 (enExample)
KR (1) KR20100135886A (enExample)
CN (1) CN102083443B (enExample)
AU (1) AU2009234156A1 (enExample)
BR (1) BRPI0911195A2 (enExample)
CA (1) CA2721082A1 (enExample)
EA (1) EA201001450A1 (enExample)
ES (1) ES2569608T3 (enExample)
IL (1) IL208565A0 (enExample)
MX (1) MX2010011050A (enExample)
WO (1) WO2009126822A2 (enExample)
ZA (1) ZA201007735B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5562939B2 (ja) 2008-04-09 2014-07-30 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法
EA201101349A1 (ru) * 2009-04-09 2012-05-30 Университет Северной Каролины В Чапел-Хилл Методы лечения отека, связанного с ишемией-реперфузией
CN103160570A (zh) * 2011-12-09 2013-06-19 彩虹天健康科技研究(北京)有限责任公司 Unc-51激酶和pp1磷酸酶相互作用机制的发现
EP3752182B1 (en) * 2018-02-12 2024-05-15 Inimmune Corporation Toll-like receptor ligands
CN108836971B (zh) * 2018-08-16 2020-10-30 青岛大学 Ws6对小梁网细胞肌动蛋白形成的影响

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5628984A (en) 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6113918A (en) 1997-05-08 2000-09-05 Ribi Immunochem Research, Inc. Aminoalkyl glucosamine phosphate compounds and their use as adjuvants and immunoeffectors
US6013640A (en) * 1998-08-21 2000-01-11 Ribi Immunochem Research, Inc. Phosphoglycolipid and methods for its use
PT1252293E (pt) * 2000-01-19 2013-01-23 Univ North Carolina Fonte de tecido de fígado
US6699846B2 (en) 2000-03-17 2004-03-02 Corixa Corporation Mono- and disaccharides for the treatment of nitric oxide related disorders
WO2003105909A1 (ja) * 2002-06-13 2003-12-24 三菱ウェルファーマ株式会社 肝虚血再灌流傷害の予防及び／又は治療のための医薬並びに移植肝臓の保護剤
US7960522B2 (en) 2003-01-06 2011-06-14 Corixa Corporation Certain aminoalkyl glucosaminide phosphate compounds and their use
JP2007514648A (ja) 2003-10-24 2007-06-07 エーザイ株式会社 Ｔｏｌｌ−ｌｉｋｅｒｅｃｅｐｔｏｒ２に関連する疾患及び状態を治療するための化合物及び方法
US7928132B2 (en) 2004-08-06 2011-04-19 Ohio University Methods for the amelioration of episodes of acute or chronic ulcerative colitis
US20060211752A1 (en) 2004-03-16 2006-09-21 Kohn Leonard D Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
JP2007534775A (ja) * 2004-05-28 2007-11-29 セダーズ−シナイ メディカル センター 脈管の疾患を処置するための方法
ITMI20060530A1 (it) * 2006-03-22 2007-09-23 Univ Milano Bicocca Antinfiammatori a struttura monosaccaridica
EP2170366B1 (en) 2007-08-03 2013-11-06 Opsona Therapeutics Limited Use of tlr-2 antagonists for treatment of reperfusion injury and tissue damage
JP5562939B2 (ja) 2008-04-09 2014-07-30 ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル アクチン細胞骨格再編成及び細胞間ギャップ形成調節の方法
EA201101349A1 (ru) 2009-04-09 2012-05-30 Университет Северной Каролины В Чапел-Хилл Методы лечения отека, связанного с ишемией-реперфузией

Also Published As

Publication number Publication date
US8809303B2 (en) 2014-08-19
WO2009126822A2 (en) 2009-10-15
CN102083443A (zh) 2011-06-01
KR20100135886A (ko) 2010-12-27
MX2010011050A (es) 2010-11-01
EP2268286A4 (en) 2011-10-12
JP5562939B2 (ja) 2014-07-30
US20110053871A1 (en) 2011-03-03
JP2011516572A (ja) 2011-05-26
AU2009234156A1 (en) 2009-10-15
EP2268286A1 (en) 2011-01-05
CA2721082A1 (en) 2009-10-15
WO2009126822A9 (en) 2009-12-17
IL208565A0 (en) 2010-12-30
ES2569608T3 (es) 2016-05-11
CN102083443B (zh) 2014-01-15
BRPI0911195A2 (pt) 2017-06-20
EP2268286B1 (en) 2016-04-06
EA201001450A1 (ru) 2011-08-30

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