JP2011514153A5 - - Google Patents

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Publication number
JP2011514153A5
JP2011514153A5 JP2010547110A JP2010547110A JP2011514153A5 JP 2011514153 A5 JP2011514153 A5 JP 2011514153A5 JP 2010547110 A JP2010547110 A JP 2010547110A JP 2010547110 A JP2010547110 A JP 2010547110A JP 2011514153 A5 JP2011514153 A5 JP 2011514153A5
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JP
Japan
Prior art keywords
enzyme
dehydrogenase
stabilized
independently
stable coenzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010547110A
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English (en)
Japanese (ja)
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JP2011514153A (ja
JP5758128B2 (ja
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Publication date
Priority claimed from EP08003054A external-priority patent/EP2093284A1/de
Application filed filed Critical
Publication of JP2011514153A publication Critical patent/JP2011514153A/ja
Publication of JP2011514153A5 publication Critical patent/JP2011514153A5/ja
Application granted granted Critical
Publication of JP5758128B2 publication Critical patent/JP5758128B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010547110A 2008-02-19 2009-02-19 安定な補酵素による脱水素酵素の安定化 Expired - Fee Related JP5758128B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08003054A EP2093284A1 (de) 2008-02-19 2008-02-19 Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
EP08003054.7 2008-02-19
PCT/EP2009/001206 WO2009103540A1 (de) 2008-02-19 2009-02-19 Stabilisierung von dehydrogenasen mit stabilen coenzymen

Publications (3)

Publication Number Publication Date
JP2011514153A JP2011514153A (ja) 2011-05-06
JP2011514153A5 true JP2011514153A5 (https=) 2012-03-22
JP5758128B2 JP5758128B2 (ja) 2015-08-05

Family

ID=39768713

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010547110A Expired - Fee Related JP5758128B2 (ja) 2008-02-19 2009-02-19 安定な補酵素による脱水素酵素の安定化
JP2011550531A Expired - Fee Related JP6113405B2 (ja) 2008-02-19 2010-02-12 乾式試薬層において低い活性を有する、速い反応速度の酵素

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011550531A Expired - Fee Related JP6113405B2 (ja) 2008-02-19 2010-02-12 乾式試薬層において低い活性を有する、速い反応速度の酵素

Country Status (15)

Country Link
US (2) US9896666B2 (https=)
EP (2) EP2093284A1 (https=)
JP (2) JP5758128B2 (https=)
KR (3) KR101381004B1 (https=)
CN (3) CN101945999B (https=)
AR (1) AR070436A1 (https=)
AU (1) AU2009216908B9 (https=)
BR (1) BRPI0907839A2 (https=)
CA (1) CA2721718C (https=)
HK (1) HK1208703A1 (https=)
MX (1) MX2010008920A (https=)
RU (1) RU2499834C2 (https=)
TW (1) TWI482860B (https=)
WO (1) WO2009103540A1 (https=)
ZA (1) ZA201006638B (https=)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553615B2 (en) * 2005-07-28 2009-06-30 Roche Diagnostics Operations, Inc. Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH
EP2093284A1 (de) 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
EP2398388B1 (de) 2009-02-19 2020-04-08 Roche Diabetes Care GmbH Platzsparende magazinierung analytischer hilfsmittel
KR20130127555A (ko) * 2009-02-19 2013-11-22 에프. 호프만-라 로슈 아게 건식 화학 층에서 낮은 활성을 갖는 효소의 고속 반응 속도
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2292751A1 (de) * 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
EP2513648B1 (de) * 2009-12-16 2015-05-27 F.Hoffmann-La Roche Ag Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt
EP2636750A1 (en) * 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
CN107024474B (zh) 2012-06-22 2020-11-06 霍夫曼-拉罗奇有限公司 用于检测体液中的分析物的方法和器件
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
CN104870982B (zh) 2012-12-20 2019-02-15 霍夫曼-拉罗奇有限公司 用于评估医学测量曲线的方法
KR101750638B1 (ko) 2012-12-20 2017-06-23 에프. 호프만-라 로슈 아게 체액의 샘플을 분석하는 방법
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
WO2014180939A1 (en) 2013-05-08 2014-11-13 Roche Diagnostics Gmbh Stabilization of enzymes by nicotinic acid
HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
EP3063169B1 (en) 2013-10-29 2018-10-10 F. Hoffmann-La Roche AG Nano-enzyme containers for test elements
WO2015078899A1 (en) 2013-11-27 2015-06-04 Roche Diagnostics Gmbh Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
CA2945612C (en) 2014-04-14 2019-09-10 F. Hoffmann-La Roche Ag Phenazinium mediators
EP3183246B1 (en) 2014-08-22 2020-09-23 Roche Diagnostics GmbH Redoxindicators
CN107779459B (zh) * 2016-08-31 2021-06-08 安琪酵母股份有限公司 葡萄糖脱氢酶dna分子、载体和菌株及应用
CA3035874C (en) 2016-10-05 2025-09-09 F. Hoffmann-La Roche Ag DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTICAL DIAGNOSTIC TEST ELEMENTS, AS WELL AS THEIR METHODS OF USE
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
EP3759231B1 (en) 2018-02-28 2023-10-18 F. Hoffmann-La Roche AG Biocompatibility coating for continuous analyte measurement

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1043568A1 (ru) * 1981-06-11 1983-09-23 Московский Ордена Ленина,Ордена Октябрьской Революции И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова Способ определени активности дегидрогеназ крови
DE19543493A1 (de) * 1995-11-22 1997-05-28 Boehringer Mannheim Gmbh Stabilisierte Coenzym-Lösungen und deren Verwendung zur Bestimmung von Dehydrogenasen bzw. deren Substrate im alkalischen Milieu
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
AU2001262702A1 (en) 2000-06-07 2001-12-17 Asahi Kasei Kabushiki Kaisha Coenzyme derivatives and enzymes appropriate therefor
KR100753747B1 (ko) * 2000-10-31 2007-08-31 고지 소데 신규 글루코오스 탈수소효소 및 해당 탈수소효소의제조방법
JP2003310274A (ja) * 2002-04-30 2003-11-05 Amano Enzyme Inc グルコース脱水素酵素およびそれをコードする遺伝子
KR101002194B1 (ko) 2002-05-16 2011-01-13 에프. 호프만-라 로슈 아게 중합체 층의 제조 방법
JP2007502114A (ja) 2003-08-11 2007-02-08 コデクシス, インコーポレイテッド 改良されたグルコースデヒドロゲナーゼポリペプチドおよび関連ポリヌクレオチド
EP1722670B1 (en) 2004-03-06 2013-09-25 F.Hoffmann-La Roche Ag Body fluid sampling device
US7172890B2 (en) * 2004-10-28 2007-02-06 Roche Diagnostics Gmbh Inactivated enzyme variants and associated process and reagent system
US7553615B2 (en) 2005-07-28 2009-06-30 Roche Diagnostics Operations, Inc. Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH
DE102005035461A1 (de) * 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
EP2093284A1 (de) * 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
US20110313009A1 (en) 2008-07-17 2011-12-22 Horizon Pharma Usa, Inc. Nsaid dose unit formulations with h2-receptor antagonists and methods of use
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten

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