JP2011514153A5 - - Google Patents

Download PDF

Info

Publication number
JP2011514153A5
JP2011514153A5 JP2010547110A JP2010547110A JP2011514153A5 JP 2011514153 A5 JP2011514153 A5 JP 2011514153A5 JP 2010547110 A JP2010547110 A JP 2010547110A JP 2010547110 A JP2010547110 A JP 2010547110A JP 2011514153 A5 JP2011514153 A5 JP 2011514153A5
Authority
JP
Japan
Prior art keywords
enzyme
dehydrogenase
stabilized
independently
stable coenzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010547110A
Other languages
English (en)
Japanese (ja)
Other versions
JP5758128B2 (ja
JP2011514153A (ja
Filing date
Publication date
Priority claimed from EP08003054A external-priority patent/EP2093284A1/de
Application filed filed Critical
Publication of JP2011514153A publication Critical patent/JP2011514153A/ja
Publication of JP2011514153A5 publication Critical patent/JP2011514153A5/ja
Application granted granted Critical
Publication of JP5758128B2 publication Critical patent/JP5758128B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010547110A 2008-02-19 2009-02-19 安定な補酵素による脱水素酵素の安定化 Expired - Fee Related JP5758128B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08003054.7 2008-02-19
EP08003054A EP2093284A1 (de) 2008-02-19 2008-02-19 Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
PCT/EP2009/001206 WO2009103540A1 (de) 2008-02-19 2009-02-19 Stabilisierung von dehydrogenasen mit stabilen coenzymen

Publications (3)

Publication Number Publication Date
JP2011514153A JP2011514153A (ja) 2011-05-06
JP2011514153A5 true JP2011514153A5 (enExample) 2012-03-22
JP5758128B2 JP5758128B2 (ja) 2015-08-05

Family

ID=39768713

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010547110A Expired - Fee Related JP5758128B2 (ja) 2008-02-19 2009-02-19 安定な補酵素による脱水素酵素の安定化
JP2011550531A Expired - Fee Related JP6113405B2 (ja) 2008-02-19 2010-02-12 乾式試薬層において低い活性を有する、速い反応速度の酵素

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011550531A Expired - Fee Related JP6113405B2 (ja) 2008-02-19 2010-02-12 乾式試薬層において低い活性を有する、速い反応速度の酵素

Country Status (15)

Country Link
US (2) US9896666B2 (enExample)
EP (2) EP2093284A1 (enExample)
JP (2) JP5758128B2 (enExample)
KR (3) KR20130081300A (enExample)
CN (3) CN101945999B (enExample)
AR (1) AR070436A1 (enExample)
AU (1) AU2009216908B9 (enExample)
BR (1) BRPI0907839A2 (enExample)
CA (1) CA2721718C (enExample)
HK (1) HK1208703A1 (enExample)
MX (1) MX2010008920A (enExample)
RU (1) RU2499834C2 (enExample)
TW (1) TWI482860B (enExample)
WO (1) WO2009103540A1 (enExample)
ZA (1) ZA201006638B (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7553615B2 (en) * 2005-07-28 2009-06-30 Roche Diagnostics Operations, Inc. Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH
EP2093284A1 (de) 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
KR20130127555A (ko) * 2009-02-19 2013-11-22 에프. 호프만-라 로슈 아게 건식 화학 층에서 낮은 활성을 갖는 효소의 고속 반응 속도
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2226007A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Testelementmagazin mit abgedeckten Testfeldern
EP2398388B1 (de) 2009-02-19 2020-04-08 Roche Diabetes Care GmbH Platzsparende magazinierung analytischer hilfsmittel
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
EP2292751A1 (de) * 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
CN102741694B (zh) * 2009-12-16 2014-12-24 霍夫曼-拉罗奇有限公司 借助于受保护的分析物的控释来检测测试元件中酶的分解
EP2636750A1 (en) * 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
KR101700022B1 (ko) 2012-06-22 2017-02-13 에프. 호프만-라 로슈 아게 체액에서 분석물질을 검출하는 방법 및 디바이스
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
JP6462585B2 (ja) 2012-12-20 2019-01-30 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 医学的測定曲線の評価方法
CN104854457B (zh) 2012-12-20 2016-09-14 霍夫曼-拉罗奇有限公司 用于分析体液样本的方法
EP2781919A1 (en) 2013-03-19 2014-09-24 Roche Diagniostics GmbH Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid
WO2014180939A1 (en) 2013-05-08 2014-11-13 Roche Diagnostics Gmbh Stabilization of enzymes by nicotinic acid
HK1213296A1 (zh) * 2013-06-04 2016-06-30 豪夫迈‧罗氏有限公司 用於fret的新化合物及与其相关的方法
WO2015063025A1 (en) 2013-10-29 2015-05-07 F. Hoffmann-La Roche Ag Nano-enzyme containers for test elements
EP3074524B1 (en) 2013-11-27 2019-11-06 Roche Diabetes Care GmbH Composition comprising up-converting phosphors for detecting an analyte
EP2927319A1 (en) 2014-03-31 2015-10-07 Roche Diagnostics GmbH High load enzyme immobilization by crosslinking
JP6522003B2 (ja) 2014-04-14 2019-05-29 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft フェナジニウムメディエーター
WO2016026959A1 (en) 2014-08-22 2016-02-25 Roche Diagnostics Gmbh Redoxindicators
CN107779459B (zh) * 2016-08-31 2021-06-08 安琪酵母股份有限公司 葡萄糖脱氢酶dna分子、载体和菌株及应用
EP4481375A3 (en) 2016-10-05 2025-04-02 F. Hoffmann-La Roche AG Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same
EP3339431A1 (en) 2016-12-22 2018-06-27 Roche Diabetes Care GmbH Glucose dehydrogenase variants with improved properties
RU2754453C1 (ru) 2018-02-28 2021-09-02 Ф. Хоффманн-Ля Рош Аг Обеспечивающее биосовместимость покрытие для непрерывного измерения аналита

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1043568A1 (ru) * 1981-06-11 1983-09-23 Московский Ордена Ленина,Ордена Октябрьской Революции И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова Способ определени активности дегидрогеназ крови
DE19543493A1 (de) * 1995-11-22 1997-05-28 Boehringer Mannheim Gmbh Stabilisierte Coenzym-Lösungen und deren Verwendung zur Bestimmung von Dehydrogenasen bzw. deren Substrate im alkalischen Milieu
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
WO2001094370A1 (en) 2000-06-07 2001-12-13 Wako Pure Chemical Industries, Ltd. Coenzyme derivatives and enzymes appropriate therefor
AU2002210991B2 (en) * 2000-10-31 2006-08-10 Koji Sode Novel glucose dehydrogenase and process for producing the dehydrogenase
JP2003310274A (ja) * 2002-04-30 2003-11-05 Amano Enzyme Inc グルコース脱水素酵素およびそれをコードする遺伝子
KR101002194B1 (ko) 2002-05-16 2011-01-13 에프. 호프만-라 로슈 아게 중합체 층의 제조 방법
BRPI0413492A (pt) 2003-08-11 2006-10-17 Codexis Inc polipeptìdeo, polinucleotìdeo, sequência de ácido nucleico isolado, vetor de expressão, célula hospedeira, método de preparar um polipeptìdeo de gdh, e, composição
PL1722670T3 (pl) 2004-03-06 2014-03-31 Hoffmann La Roche Urządzenie do pobierania próbki płynu ustrojowego
US7172890B2 (en) * 2004-10-28 2007-02-06 Roche Diagnostics Gmbh Inactivated enzyme variants and associated process and reagent system
DE102005035461A1 (de) 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
US7553615B2 (en) 2005-07-28 2009-06-30 Roche Diagnostics Operations, Inc. Compounds, methods, complexes, apparatuses and uses relating to stabile forms of NAD/NADH
EP2093284A1 (de) * 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
WO2010009432A1 (en) 2008-07-17 2010-01-21 Horizon Therapeutics, Inc. Nsaid dose unit formulations with h2-receptor antagonists and methods of use
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten

Similar Documents

Publication Publication Date Title
JP2013502212A5 (enExample)
RU2010138610A (ru) Стабилизация дегидрогеназ стабильными коферментами
JP2012517816A5 (enExample)
JP5851401B2 (ja) 安定な補酵素による酵素の安定化
KR101483829B1 (ko) 안정한 nad/nadh 유도체
JP2009502844A5 (enExample)
US10890557B2 (en) Electrochemical biosensor
JP2007054052A (ja) Nad/nadhの安定化
ES2323081T3 (es) Procedimiento para la produccion de 2-butanol mediante reduccion enzimatica de 2-butanona en un sistema de dos fases.
JP2021126124A5 (enExample)
JP2017000137A5 (enExample)
TW200718785A (en) A process for improving the thermal stability of a composition containing a soluble coenzyme conjugated glucose dehydrogenase (GDH)
JP2014150777A (ja) 凍結保護剤
AU2012203453B2 (en) Stabilization of dehydrogenases using stable coenzymes
Schomburg et al. alcohol dehydrogenase (cytochrome c) 1.1. 2.8
JP2009019021A (ja) ホモイソクエン酸脱水素酵素の阻害剤
HK1152728B (en) Stabilization of dehydrogenases using stable coenzymes
HK1152728A (en) Stabilization of dehydrogenases using stable coenzymes