RU2499834C2 - Стабилизация дегидрогеназ стабильными коферментами - Google Patents
Стабилизация дегидрогеназ стабильными коферментами Download PDFInfo
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- RU2499834C2 RU2499834C2 RU2010138610/10A RU2010138610A RU2499834C2 RU 2499834 C2 RU2499834 C2 RU 2499834C2 RU 2010138610/10 A RU2010138610/10 A RU 2010138610/10A RU 2010138610 A RU2010138610 A RU 2010138610A RU 2499834 C2 RU2499834 C2 RU 2499834C2
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- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
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- C12Y101/01028—D-Lactate dehydrogenase (1.1.1.28)
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- C12Y101/01037—Malate dehydrogenase (1.1.1.37)
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- C12Y101/01047—Glucose 1-dehydrogenase (1.1.1.47)
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- C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
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- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| PCT/EP2009/001206 WO2009103540A1 (de) | 2008-02-19 | 2009-02-19 | Stabilisierung von dehydrogenasen mit stabilen coenzymen |
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| JP4786451B2 (ja) * | 2005-07-28 | 2011-10-05 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | Ｎａｄ／ｎａｄｈの安定化 |
| EP2093284A1 (de) | 2008-02-19 | 2009-08-26 | F.Hoffmann-La Roche Ag | Stabilisierung von Dehydrogenasen mit stabilen Coenzymen |
| EP2226007A1 (de) | 2009-02-19 | 2010-09-08 | Roche Diagnostics GmbH | Testelementmagazin mit abgedeckten Testfeldern |
| EP2226008A1 (de) | 2009-02-19 | 2010-09-08 | Roche Diagnostics GmbH | Verfahren zur Herstellung eines analytischen Magazins |
| CA2750474C (en) * | 2009-02-19 | 2017-07-25 | F. Hoffmann-La Roche Ag | Fast reaction kinetics of enzymes having low activity in dry chemistry layers |
| CN102325496B (zh) | 2009-02-19 | 2015-10-07 | 霍夫曼-拉罗奇有限公司 | 分析辅助工具的节省空间的储存 |
| EP2398909B1 (de) | 2009-02-19 | 2015-07-22 | F. Hoffmann-La Roche AG | Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten |
| EP2292751A1 (de) * | 2009-08-20 | 2011-03-09 | Roche Diagnostics GmbH | Stabilisierung von Enzymen mit stabilen Coenzymen |
| EP2513648B1 (de) * | 2009-12-16 | 2015-05-27 | F.Hoffmann-La Roche Ag | Detektion der zersetzung von enzymen in einem testelement durch kontrollierte freisetzung von geschütztem analyt |
| EP2636750A1 (en) * | 2012-03-06 | 2013-09-11 | Roche Diagniostics GmbH | Compatible solute ectoine as well as derivatives thereof for enzyme stabilization |
| EP2864765B1 (en) | 2012-06-22 | 2021-04-28 | Roche Diabetes Care GmbH | Method and device for detecting an analyte in a body fluid |
| US8920628B2 (en) | 2012-11-02 | 2014-12-30 | Roche Diagnostics Operations, Inc. | Systems and methods for multiple analyte analysis |
| US8921061B2 (en) * | 2012-11-02 | 2014-12-30 | Roche Diagnostics Operations, Inc. | Reagent materials and associated test elements |
| EP2936155B1 (en) | 2012-12-20 | 2018-12-12 | Roche Diabetes Care GmbH | Method for analyzing a sample of a body fluid |
| KR101789893B1 (ko) | 2012-12-20 | 2017-11-20 | 에프. 호프만-라 로슈 아게 | 의학적 측정 곡선들을 평가하기 위한 방법 |
| EP2781919A1 (en) | 2013-03-19 | 2014-09-24 | Roche Diagniostics GmbH | Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid |
| EP2994536B1 (en) | 2013-05-08 | 2017-06-14 | Roche Diabetes Care GmbH | Stabilization of enzymes by nicotinic acid |
| EP3004372A1 (en) * | 2013-06-04 | 2016-04-13 | Roche Diagnostics GmbH | Novel compounds useful for fret and methods related thereto |
| WO2015063025A1 (en) | 2013-10-29 | 2015-05-07 | F. Hoffmann-La Roche Ag | Nano-enzyme containers for test elements |
| WO2015078899A1 (en) | 2013-11-27 | 2015-06-04 | Roche Diagnostics Gmbh | Composition comprising up-converting phosphors for detecting an analyte |
| EP2927319A1 (en) | 2014-03-31 | 2015-10-07 | Roche Diagnostics GmbH | High load enzyme immobilization by crosslinking |
| CN106164054B (zh) | 2014-04-14 | 2019-05-07 | 豪夫迈·罗氏有限公司 | 吩嗪介导剂 |
| EP3183246B1 (en) | 2014-08-22 | 2020-09-23 | Roche Diagnostics GmbH | Redoxindicators |
| CN107779459B (zh) * | 2016-08-31 | 2021-06-08 | 安琪酵母股份有限公司 | 葡萄糖脱氢酶dna分子、载体和菌株及应用 |
| JP2019529935A (ja) | 2016-10-05 | 2019-10-17 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 多検体診断用試験エレメントのための検出試薬および電極配置、ならびにそれらを使用する方法 |
| EP3339431A1 (en) | 2016-12-22 | 2018-06-27 | Roche Diabetes Care GmbH | Glucose dehydrogenase variants with improved properties |
| HUE064713T2 (hu) | 2018-02-28 | 2024-04-28 | Hoffmann La Roche | Biokompatibilitási bevonat folyamatos analitméréshez |
| CN122235370A (zh) * | 2026-05-20 | 2026-06-19 | 山东农业大学 | 一种与苹果果实山梨醇含量相关的分子标记、检测试剂及其应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| SU1043568A1 (ru) * | 1981-06-11 | 1983-09-23 | Московский Ордена Ленина,Ордена Октябрьской Революции И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова | Способ определени активности дегидрогеназ крови |
| WO1998033936A1 (en) * | 1997-02-04 | 1998-08-06 | Specialty Assays, Inc. | The use of nadph and nadh analogs in the measurement of enzyme activities and metabolites |
| WO2001049247A2 (en) * | 1999-12-30 | 2001-07-12 | Specialty Assays, Inc. | Assays for analytes and enzymes practiced in the presence of nad and nadp analogues, and related assay kits |
| WO2007012494A1 (de) * | 2005-07-28 | 2007-02-01 | F.Hoffmann-La Roche Ag | Stabile nad/nadh-derivate |
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| DE19543493A1 (de) * | 1995-11-22 | 1997-05-28 | Boehringer Mannheim Gmbh | Stabilisierte Coenzym-Lösungen und deren Verwendung zur Bestimmung von Dehydrogenasen bzw. deren Substrate im alkalischen Milieu |
| WO2001094370A1 (en) | 2000-06-07 | 2001-12-13 | Wako Pure Chemical Industries, Ltd. | Coenzyme derivatives and enzymes appropriate therefor |
| EP1331272B1 (en) | 2000-10-31 | 2007-06-06 | Koji Sode | Novel glucose dehydrogenase and process for producing the dehydrogenase |
| JP2003310274A (ja) * | 2002-04-30 | 2003-11-05 | Amano Enzyme Inc | グルコース脱水素酵素およびそれをコードする遺伝子 |
| ATE345396T1 (de) | 2002-05-16 | 2006-12-15 | Hoffmann La Roche | Verfahren zur herstellung von polymerschichten |
| MXPA06001719A (es) | 2003-08-11 | 2006-05-19 | Codexis Inc | Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados. |
| WO2005084530A2 (en) | 2004-03-06 | 2005-09-15 | F. Hoffmann-La Roche Ag | Body fluid sampling device |
| US7172890B2 (en) * | 2004-10-28 | 2007-02-06 | Roche Diagnostics Gmbh | Inactivated enzyme variants and associated process and reagent system |
| JP4786451B2 (ja) | 2005-07-28 | 2011-10-05 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | Ｎａｄ／ｎａｄｈの安定化 |
| EP2093284A1 (de) * | 2008-02-19 | 2009-08-26 | F.Hoffmann-La Roche Ag | Stabilisierung von Dehydrogenasen mit stabilen Coenzymen |
| US20110313009A1 (en) | 2008-07-17 | 2011-12-22 | Horizon Pharma Usa, Inc. | Nsaid dose unit formulations with h2-receptor antagonists and methods of use |
| EP2398909B1 (de) | 2009-02-19 | 2015-07-22 | F. Hoffmann-La Roche AG | Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten |
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| SU1043568A1 (ru) * | 1981-06-11 | 1983-09-23 | Московский Ордена Ленина,Ордена Октябрьской Революции И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова | Способ определени активности дегидрогеназ крови |
| WO1998033936A1 (en) * | 1997-02-04 | 1998-08-06 | Specialty Assays, Inc. | The use of nadph and nadh analogs in the measurement of enzyme activities and metabolites |
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