JP2011513420A - レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置 - Google Patents

レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置 Download PDF

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Publication number
JP2011513420A
JP2011513420A JP2010549844A JP2010549844A JP2011513420A JP 2011513420 A JP2011513420 A JP 2011513420A JP 2010549844 A JP2010549844 A JP 2010549844A JP 2010549844 A JP2010549844 A JP 2010549844A JP 2011513420 A JP2011513420 A JP 2011513420A
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alkyl
hydroxy
aryl
haloalkyl
formula
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JP2011513420A5 (https=
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ガイ エム． ミラー，
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エジソン ファーマシューティカルズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2010549844A 2008-03-05 2009-03-04 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置 Withdrawn JP2011513420A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6833008P 2008-03-05 2008-03-05
US19119808P 2008-09-05 2008-09-05
PCT/US2009/035996 WO2009111543A2 (en) 2008-03-05 2009-03-04 Treatment of hearing and balance impairments with redox-active therapeutics

Related Child Applications (1)

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JP2014016459A Division JP6131200B2 (ja) 2008-03-05 2014-01-31 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置

Publications (2)

Publication Number Publication Date
JP2011513420A true JP2011513420A (ja) 2011-04-28
JP2011513420A5 JP2011513420A5 (https=) 2013-04-04

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Family Applications (4)

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JP2010549844A Withdrawn JP2011513420A (ja) 2008-03-05 2009-03-04 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置
JP2014016459A Active JP6131200B2 (ja) 2008-03-05 2014-01-31 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置
JP2015160272A Withdrawn JP2015205938A (ja) 2008-03-05 2015-08-17 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置
JP2017151442A Pending JP2017193590A (ja) 2008-03-05 2017-08-04 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置

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JP2014016459A Active JP6131200B2 (ja) 2008-03-05 2014-01-31 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置
JP2015160272A Withdrawn JP2015205938A (ja) 2008-03-05 2015-08-17 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置
JP2017151442A Pending JP2017193590A (ja) 2008-03-05 2017-08-04 レドックス活性治療薬を用いる聴覚機能障害および平衡機能障害の処置

Country Status (5)

Country Link
US (3) US20110046156A1 (https=)
EP (1) EP2262519A4 (https=)
JP (4) JP2011513420A (https=)
CA (1) CA2717741C (https=)
WO (1) WO2009111543A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
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JP2018500326A (ja) * 2014-12-16 2018-01-11 バイオエレクトロン テクノロジー コーポレイション （ｒ）−２−ヒドロキシ−２−メチル−４−（２，４，５−トリメチル−３，６−ジオキソシクロヘキサ−１，４−ジエニル）ブタンアミドの多形性形態および非晶質形態
JP2018531250A (ja) * 2015-10-08 2018-10-25 コンドリオン アイピー ビー．ブイ．Ｋｈｏｎｄｒｉｏｎ Ｉｐ Ｂ．Ｖ． ミトコンドリア疾患を治療する新規化合物
JP2022074312A (ja) * 2020-11-04 2022-05-18 国立大学法人 東京大学 騒音性難聴の予防剤

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Cited By (11)

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JP2018500326A (ja) * 2014-12-16 2018-01-11 バイオエレクトロン テクノロジー コーポレイション （ｒ）−２−ヒドロキシ−２−メチル−４−（２，４，５−トリメチル−３，６−ジオキソシクロヘキサ−１，４−ジエニル）ブタンアミドの多形性形態および非晶質形態
JP2020111582A (ja) * 2014-12-16 2020-07-27 バイオエレクトロン テクノロジー コーポレイション （ｒ）−２−ヒドロキシ−２−メチル−４−（２，４，５−トリメチル−３，６−ジオキソシクロヘキサ−１，４−ジエニル）ブタンアミドの多形性形態および非晶質形態
JP2021185199A (ja) * 2014-12-16 2021-12-09 ピーティーシー セラピューティクス， インコーポレイテッド （ｒ）−２−ヒドロキシ−２−メチル−４−（２，４，５−トリメチル−３，６−ジオキソシクロヘキサ−１，４−ジエニル）ブタンアミドの多形性形態および非晶質形態
JP7111759B2 (ja) 2014-12-16 2022-08-02 ピーティーシー セラピューティクス， インコーポレイテッド （ｒ）－２－ヒドロキシ－２－メチル－４－（２，４，５－トリメチル－３，６－ジオキソシクロヘキサ－１，４－ジエニル）ブタンアミドの多形性形態および非晶質形態
JP2022116352A (ja) * 2014-12-16 2022-08-09 ピーティーシー セラピューティクス， インコーポレイテッド （ｒ）－２－ヒドロキシ－２－メチル－４－（２，４，５－トリメチル－３，６－ジオキソシクロヘキサ－１，４－ジエニル）ブタンアミドの多形性形態および非晶質形態
JP7277061B2 (ja) 2014-12-16 2023-05-18 ピーティーシー セラピューティクス， インコーポレイテッド （ｒ）－２－ヒドロキシ－２－メチル－４－（２，４，５－トリメチル－３，６－ジオキソシクロヘキサ－１，４－ジエニル）ブタンアミドの多形性形態および非晶質形態
JP7541546B2 (ja) 2014-12-16 2024-08-28 ピーティーシー セラピューティクス， インコーポレイテッド （ｒ）－２－ヒドロキシ－２－メチル－４－（２，４，５－トリメチル－３，６－ジオキソシクロヘキサ－１，４－ジエニル）ブタンアミドの多形性形態および非晶質形態
JP2018531250A (ja) * 2015-10-08 2018-10-25 コンドリオン アイピー ビー．ブイ．Ｋｈｏｎｄｒｉｏｎ Ｉｐ Ｂ．Ｖ． ミトコンドリア疾患を治療する新規化合物
JP2020073524A (ja) * 2015-10-08 2020-05-14 コンドリオン アイピー ビー．ブイ．Ｋｈｏｎｄｒｉｏｎ Ｉｐ Ｂ．Ｖ． ミトコンドリア疾患を治療する新規化合物
JP2022074312A (ja) * 2020-11-04 2022-05-18 国立大学法人 東京大学 騒音性難聴の予防剤
JP7531808B2 (ja) 2020-11-04 2024-08-13 国立大学法人 東京大学 騒音性難聴の予防剤

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US20110046156A1 (en) 2011-02-24
JP2017193590A (ja) 2017-10-26
WO2009111543A2 (en) 2009-09-11
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US20140249160A1 (en) 2014-09-04

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