JP2011513315A5 - - Google Patents
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- Publication number
- JP2011513315A5 JP2011513315A5 JP2010548807A JP2010548807A JP2011513315A5 JP 2011513315 A5 JP2011513315 A5 JP 2011513315A5 JP 2010548807 A JP2010548807 A JP 2010548807A JP 2010548807 A JP2010548807 A JP 2010548807A JP 2011513315 A5 JP2011513315 A5 JP 2011513315A5
- Authority
- JP
- Japan
- Prior art keywords
- antimetabolite
- pharmaceutical composition
- use according
- administered
- rukanton
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000340 anti-metabolite Effects 0.000 claims 21
- 229940100197 antimetabolite Drugs 0.000 claims 21
- 239000002256 antimetabolite Substances 0.000 claims 21
- 239000008194 pharmaceutical composition Substances 0.000 claims 21
- 206010028980 Neoplasm Diseases 0.000 claims 3
- 201000011510 cancer Diseases 0.000 claims 3
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000004052 folic acid antagonist Substances 0.000 claims 2
- 201000005202 lung cancer Diseases 0.000 claims 2
- 208000020816 lung neoplasm Diseases 0.000 claims 2
- 230000003432 anti-folate effect Effects 0.000 claims 1
- 229940127074 antifolate Drugs 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940014144 folate Drugs 0.000 claims 1
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims 1
- 235000019152 folic acid Nutrition 0.000 claims 1
- 239000011724 folic acid Substances 0.000 claims 1
- 238000001794 hormone therapy Methods 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- FBQPGGIHOFZRGH-UHFFFAOYSA-N lucanthone Chemical compound S1C2=CC=CC=C2C(=O)C2=C1C(C)=CC=C2NCCN(CC)CC FBQPGGIHOFZRGH-UHFFFAOYSA-N 0.000 claims 1
- 229950005239 lucanthone Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 1
- 229960005079 pemetrexed Drugs 0.000 claims 1
- QOFFJEBXNKRSPX-ZDUSSCGKSA-N pemetrexed Chemical group C1=N[C]2NC(N)=NC(=O)C2=C1CCC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 QOFFJEBXNKRSPX-ZDUSSCGKSA-N 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3283108P | 2008-02-29 | 2008-02-29 | |
| US61/032,831 | 2008-02-29 | ||
| PCT/US2009/034629 WO2009108573A1 (en) | 2008-02-29 | 2009-02-20 | Combination anti-cancer agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011513315A JP2011513315A (ja) | 2011-04-28 |
| JP2011513315A5 true JP2011513315A5 (enExample) | 2012-04-05 |
| JP5590560B2 JP5590560B2 (ja) | 2014-09-17 |
Family
ID=40566524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010548807A Expired - Fee Related JP5590560B2 (ja) | 2008-02-29 | 2009-02-20 | 組合せ抗がん剤 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20090221615A1 (enExample) |
| EP (1) | EP2257285A1 (enExample) |
| JP (1) | JP5590560B2 (enExample) |
| KR (1) | KR20100126453A (enExample) |
| CN (1) | CN102014895A (enExample) |
| AU (1) | AU2009219464B2 (enExample) |
| BR (1) | BRPI0908398A2 (enExample) |
| CA (1) | CA2717100A1 (enExample) |
| IL (1) | IL207859A (enExample) |
| MX (1) | MX2010009502A (enExample) |
| RU (1) | RU2516027C2 (enExample) |
| WO (1) | WO2009108573A1 (enExample) |
| ZA (1) | ZA201006123B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6182313B2 (ja) * | 2010-03-08 | 2017-08-16 | スペクトラム ファーマシューティカルズ インコーポレイテッド | 癌治療のためのチオキサントンをベースとしたオートファジー阻害剤療法 |
| EP2425830A1 (en) | 2010-09-03 | 2012-03-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synergistic drug combination for the treatment of cancer |
| WO2023114245A2 (en) * | 2021-12-14 | 2023-06-22 | Radin Daniel Pierce | Compositions and methods for treating cancers of the central nervous system (cns), including glioblastoma and chemoresistant cns tumors, and related compositions and methods for inhibiting and eliminating cns cancer stem cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ504108A (en) * | 1997-09-26 | 2002-06-28 | Noven Pharma | Bioadhesive compositions comprising a polyvinylpyrrolidone polymer and methods for topical administration of active agents |
| US6391911B1 (en) * | 1999-02-26 | 2002-05-21 | Robert E. Bases | Coadministration of lucanthone and radiation for treatment of cancer |
| EP1971338B8 (en) * | 2005-12-22 | 2011-09-21 | AstraZeneca AB | Combination of zd6474 and pemetrexed |
| JP2009520787A (ja) * | 2005-12-22 | 2009-05-28 | アストラゼネカ アクチボラグ | Ａｚｄ２１７１およびペメトレキセドの組み合わせ |
-
2009
- 2009-02-19 US US12/389,318 patent/US20090221615A1/en not_active Abandoned
- 2009-02-20 KR KR1020107021665A patent/KR20100126453A/ko not_active Abandoned
- 2009-02-20 CN CN2009801154644A patent/CN102014895A/zh active Pending
- 2009-02-20 EP EP09714301A patent/EP2257285A1/en not_active Withdrawn
- 2009-02-20 RU RU2010139840/14A patent/RU2516027C2/ru not_active IP Right Cessation
- 2009-02-20 BR BRPI0908398-7A patent/BRPI0908398A2/pt not_active Application Discontinuation
- 2009-02-20 WO PCT/US2009/034629 patent/WO2009108573A1/en not_active Ceased
- 2009-02-20 AU AU2009219464A patent/AU2009219464B2/en not_active Ceased
- 2009-02-20 CA CA2717100A patent/CA2717100A1/en not_active Abandoned
- 2009-02-20 MX MX2010009502A patent/MX2010009502A/es active IP Right Grant
- 2009-02-20 JP JP2010548807A patent/JP5590560B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-27 ZA ZA2010/06123A patent/ZA201006123B/en unknown
- 2010-08-29 IL IL207859A patent/IL207859A/en not_active IP Right Cessation
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