JP5590560B2 - 組合せ抗がん剤 - Google Patents

組合せ抗がん剤 Download PDF

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Publication number
JP5590560B2
JP5590560B2 JP2010548807A JP2010548807A JP5590560B2 JP 5590560 B2 JP5590560 B2 JP 5590560B2 JP 2010548807 A JP2010548807 A JP 2010548807A JP 2010548807 A JP2010548807 A JP 2010548807A JP 5590560 B2 JP5590560 B2 JP 5590560B2
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JP
Japan
Prior art keywords
lucanton
pemetrexed
pharmaceutical composition
administered
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2010548807A
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English (en)
Japanese (ja)
Other versions
JP2011513315A (ja
JP2011513315A5 (enExample
Inventor
レディ,グル
レナズ,ルイジ
Original Assignee
スペクトラム・ファーマシューティカルス・インコーポレーテッド
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Application filed by スペクトラム・ファーマシューティカルス・インコーポレーテッド filed Critical スペクトラム・ファーマシューティカルス・インコーポレーテッド
Publication of JP2011513315A publication Critical patent/JP2011513315A/ja
Publication of JP2011513315A5 publication Critical patent/JP2011513315A5/ja
Application granted granted Critical
Publication of JP5590560B2 publication Critical patent/JP5590560B2/ja
Expired - Fee Related legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/382Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
JP2010548807A 2008-02-29 2009-02-20 組合せ抗がん剤 Expired - Fee Related JP5590560B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3283108P 2008-02-29 2008-02-29
US61/032,831 2008-02-29
PCT/US2009/034629 WO2009108573A1 (en) 2008-02-29 2009-02-20 Combination anti-cancer agents

Publications (3)

Publication Number Publication Date
JP2011513315A JP2011513315A (ja) 2011-04-28
JP2011513315A5 JP2011513315A5 (enExample) 2012-04-05
JP5590560B2 true JP5590560B2 (ja) 2014-09-17

Family

ID=40566524

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010548807A Expired - Fee Related JP5590560B2 (ja) 2008-02-29 2009-02-20 組合せ抗がん剤

Country Status (13)

Country Link
US (1) US20090221615A1 (enExample)
EP (1) EP2257285A1 (enExample)
JP (1) JP5590560B2 (enExample)
KR (1) KR20100126453A (enExample)
CN (1) CN102014895A (enExample)
AU (1) AU2009219464B2 (enExample)
BR (1) BRPI0908398A2 (enExample)
CA (1) CA2717100A1 (enExample)
IL (1) IL207859A (enExample)
MX (1) MX2010009502A (enExample)
RU (1) RU2516027C2 (enExample)
WO (1) WO2009108573A1 (enExample)
ZA (1) ZA201006123B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6182313B2 (ja) * 2010-03-08 2017-08-16 スペクトラム ファーマシューティカルズ インコーポレイテッド 癌治療のためのチオキサントンをベースとしたオートファジー阻害剤療法
EP2425830A1 (en) 2010-09-03 2012-03-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Synergistic drug combination for the treatment of cancer
CA3240916A1 (en) * 2021-12-14 2023-06-22 Daniel Pierce RADIN Compositions and methods for treating cancers of the central nervous system (cns), including glioblastoma and chemoresistant cns tumors, and related compositions and methods for inhibiting and eliminating cns cancer stem cell

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015210A2 (en) * 1997-09-26 1999-04-01 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US6391911B1 (en) * 1999-02-26 2002-05-21 Robert E. Bases Coadministration of lucanthone and radiation for treatment of cancer
DK1971338T3 (da) * 2005-12-22 2011-05-23 Astrazeneca Ab Kombination af ZD6474 og pemetrexed
KR20080077678A (ko) * 2005-12-22 2008-08-25 아스트라제네카 아베 Azd2171 및 페메트렉시드의 조합물

Also Published As

Publication number Publication date
AU2009219464B2 (en) 2015-04-09
JP2011513315A (ja) 2011-04-28
ZA201006123B (en) 2011-05-25
KR20100126453A (ko) 2010-12-01
WO2009108573A1 (en) 2009-09-03
RU2516027C2 (ru) 2014-05-20
MX2010009502A (es) 2010-11-10
IL207859A0 (en) 2010-12-30
IL207859A (en) 2015-09-24
AU2009219464A1 (en) 2009-09-03
CA2717100A1 (en) 2009-09-03
EP2257285A1 (en) 2010-12-08
US20090221615A1 (en) 2009-09-03
RU2010139840A (ru) 2012-04-10
CN102014895A (zh) 2011-04-13
BRPI0908398A2 (pt) 2015-08-11

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