CA2717100A1 - Use of lucanthone in combination with an anti-metabolite to treat cancer - Google Patents
Use of lucanthone in combination with an anti-metabolite to treat cancer Download PDFInfo
- Publication number
- CA2717100A1 CA2717100A1 CA2717100A CA2717100A CA2717100A1 CA 2717100 A1 CA2717100 A1 CA 2717100A1 CA 2717100 A CA2717100 A CA 2717100A CA 2717100 A CA2717100 A CA 2717100A CA 2717100 A1 CA2717100 A1 CA 2717100A1
- Authority
- CA
- Canada
- Prior art keywords
- lucanthone
- metabolite
- administered
- therapeutically effective
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3283108P | 2008-02-29 | 2008-02-29 | |
| US61/032,831 | 2008-02-29 | ||
| PCT/US2009/034629 WO2009108573A1 (en) | 2008-02-29 | 2009-02-20 | Combination anti-cancer agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2717100A1 true CA2717100A1 (en) | 2009-09-03 |
Family
ID=40566524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2717100A Abandoned CA2717100A1 (en) | 2008-02-29 | 2009-02-20 | Use of lucanthone in combination with an anti-metabolite to treat cancer |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20090221615A1 (enExample) |
| EP (1) | EP2257285A1 (enExample) |
| JP (1) | JP5590560B2 (enExample) |
| KR (1) | KR20100126453A (enExample) |
| CN (1) | CN102014895A (enExample) |
| AU (1) | AU2009219464B2 (enExample) |
| BR (1) | BRPI0908398A2 (enExample) |
| CA (1) | CA2717100A1 (enExample) |
| IL (1) | IL207859A (enExample) |
| MX (1) | MX2010009502A (enExample) |
| RU (1) | RU2516027C2 (enExample) |
| WO (1) | WO2009108573A1 (enExample) |
| ZA (1) | ZA201006123B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2789895C (en) * | 2010-03-08 | 2019-04-09 | Spectrum Pharmaceuticals, Inc. | Thioxanthone-based autophagy inhibitor therapies to treat cancer |
| EP2425830A1 (en) | 2010-09-03 | 2012-03-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Synergistic drug combination for the treatment of cancer |
| AU2022415337A1 (en) * | 2021-12-14 | 2024-08-01 | Daniel Pierce RADIN | Compositions and methods for treating cancers of the central nervous system (cns), including glioblastoma and chemoresistant cns tumors, and related compositions and methods for inhibiting and eliminating cns cancer stem cells |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2252865T3 (es) * | 1997-09-26 | 2006-05-16 | Noven Pharmaceuticals, Inc. | Composiciones bioadhesivas y metodos para la administracion topica de agentes activos. |
| US6391911B1 (en) * | 1999-02-26 | 2002-05-21 | Robert E. Bases | Coadministration of lucanthone and radiation for treatment of cancer |
| PL1971338T3 (pl) * | 2005-12-22 | 2011-07-29 | Astrazeneca Ab | Połączenie ZD6474 i premetreksedu |
| CA2631676A1 (en) * | 2005-12-22 | 2007-06-28 | Astrazeneca Ab | Combination of azd2171 and pemetrexed |
-
2009
- 2009-02-19 US US12/389,318 patent/US20090221615A1/en not_active Abandoned
- 2009-02-20 WO PCT/US2009/034629 patent/WO2009108573A1/en not_active Ceased
- 2009-02-20 CA CA2717100A patent/CA2717100A1/en not_active Abandoned
- 2009-02-20 BR BRPI0908398-7A patent/BRPI0908398A2/pt not_active Application Discontinuation
- 2009-02-20 MX MX2010009502A patent/MX2010009502A/es active IP Right Grant
- 2009-02-20 CN CN2009801154644A patent/CN102014895A/zh active Pending
- 2009-02-20 KR KR1020107021665A patent/KR20100126453A/ko not_active Abandoned
- 2009-02-20 RU RU2010139840/14A patent/RU2516027C2/ru not_active IP Right Cessation
- 2009-02-20 AU AU2009219464A patent/AU2009219464B2/en not_active Ceased
- 2009-02-20 EP EP09714301A patent/EP2257285A1/en not_active Withdrawn
- 2009-02-20 JP JP2010548807A patent/JP5590560B2/ja not_active Expired - Fee Related
-
2010
- 2010-08-27 ZA ZA2010/06123A patent/ZA201006123B/en unknown
- 2010-08-29 IL IL207859A patent/IL207859A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2516027C2 (ru) | 2014-05-20 |
| BRPI0908398A2 (pt) | 2015-08-11 |
| AU2009219464B2 (en) | 2015-04-09 |
| JP5590560B2 (ja) | 2014-09-17 |
| CN102014895A (zh) | 2011-04-13 |
| IL207859A (en) | 2015-09-24 |
| IL207859A0 (en) | 2010-12-30 |
| JP2011513315A (ja) | 2011-04-28 |
| MX2010009502A (es) | 2010-11-10 |
| EP2257285A1 (en) | 2010-12-08 |
| RU2010139840A (ru) | 2012-04-10 |
| US20090221615A1 (en) | 2009-09-03 |
| AU2009219464A1 (en) | 2009-09-03 |
| ZA201006123B (en) | 2011-05-25 |
| KR20100126453A (ko) | 2010-12-01 |
| WO2009108573A1 (en) | 2009-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140219 |
|
| FZDE | Discontinued |
Effective date: 20170222 |