JP2011511620A - アミノ酸及びペプチド製品 - Google Patents
アミノ酸及びペプチド製品 Download PDFInfo
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- JP2011511620A JP2011511620A JP2010519884A JP2010519884A JP2011511620A JP 2011511620 A JP2011511620 A JP 2011511620A JP 2010519884 A JP2010519884 A JP 2010519884A JP 2010519884 A JP2010519884 A JP 2010519884A JP 2011511620 A JP2011511620 A JP 2011511620A
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| EP3970715A1 (en) | 2010-09-24 | 2022-03-23 | University of Florida Research Foundation, Inc. | Materials and methods for improving gastrointestinal function |
| JP2015519878A (ja) | 2012-03-26 | 2015-07-16 | プロニュートリア・インコーポレイテッドＰｒｏｎｕｔｒｉａ， Ｉｎｃ． | 栄養断片、タンパク質、および方法 |
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| EP2968241B1 (en) | 2013-03-11 | 2018-10-31 | University of Florida Research Foundation, Inc. | Materials and methods for improving lung function and for prevention and/or treatment of radiation-induced lung complications |
| JP6577453B2 (ja) * | 2013-03-14 | 2019-09-18 | ユニバーシティ オブ セントラル フロリダ リサーチ ファウンデーション，インコーポレイテッド | タンパク質のメカノ触媒的加水分解プロセスに従って生成されたアミノ酸 |
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| EP3510999A4 (en) | 2016-09-09 | 2020-03-11 | Ajinomoto Co., Inc. | PREVENTION OR REMEDY COMPOSITION AGAINST DEMENTIA OR DEPRESSION |
| US11576884B2 (en) | 2016-10-04 | 2023-02-14 | University Of Florida Research Foundation, Inc. | Amino acid compositions and uses thereof |
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| JP7082623B2 (ja) | 2016-12-21 | 2022-06-08 | ユニリーバー・アイピー・ホールディングス・ベスローテン・ヴェンノーツハップ | シスチンを有するパーソナルケア用組成物 |
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| CN106581639A (zh) * | 2017-02-07 | 2017-04-26 | 张艳飞 | 预防雾霾伤害的含有石斛提取物的饮品 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59161319A (ja) * | 1983-03-04 | 1984-09-12 | Nippon Bussan Kk | 薬理作用を有する魚貝類エキスの製造方法 |
| JPS6287058A (ja) * | 1985-10-14 | 1987-04-21 | Osajima Kazuharu | 新規ペプチド |
| JP2005534340A (ja) * | 2002-07-29 | 2005-11-17 | アミノテック アーエス | １以上の蛋白質を含有する生材料からのペプチド／アミノ酸及び油／脂肪の回収方法、その方法により製造される産物、並びにその産物の使用 |
| JP2006507838A (ja) * | 2002-12-02 | 2006-03-09 | グリーン、アース、インダストリーズ、リミテッド、ライアビリティー、カンパニー | タンパク質含有原料の加水分解のための装置および方法ならびに得られた加水分解産物の用途 |
| WO2007069716A1 (ja) * | 2005-12-16 | 2007-06-21 | Nippon Suisan Kaisha, Ltd. | 内臓脂肪蓄積抑制作用を有する組成物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2168259A1 (en) * | 1972-01-20 | 1973-08-31 | Assoc Etu Prob Nutrit On | Enzymatic hydrolysis of fish proteins - to form fractions of lipids peptides and aminoacids |
| AU605797B2 (en) * | 1987-11-04 | 1991-01-24 | Katsuhiro Osajima | Method for preparation of tastable matters consisting mainly of low molecular weight peptides |
| US20040038391A1 (en) * | 2002-02-06 | 2004-02-26 | Pyntikov Alexander V. | Amino acids factory |
| JP3691497B2 (ja) * | 2002-06-20 | 2005-09-07 | 有限会社フジ・バイオ研究所 | 魚卵外皮の酵素分解によるアミノ酸成分の製法 |
-
2008
- 2008-08-04 CA CA2695444A patent/CA2695444C/en not_active Expired - Fee Related
- 2008-08-04 BR BRPI0814745-0A2A patent/BRPI0814745A2/pt not_active Application Discontinuation
- 2008-08-04 CN CN200880110512A patent/CN101815441A/zh active Pending
- 2008-08-04 WO PCT/NO2008/000282 patent/WO2009020394A1/en not_active Ceased
- 2008-08-04 KR KR1020107004829A patent/KR20100057630A/ko not_active Ceased
- 2008-08-04 US US12/671,969 patent/US20110183040A1/en not_active Abandoned
- 2008-08-04 EP EP08793894.0A patent/EP2185004B1/en not_active Not-in-force
- 2008-08-04 JP JP2010519884A patent/JP2011511620A/ja active Pending
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2014
- 2014-03-25 US US14/224,957 patent/US20140255592A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59161319A (ja) * | 1983-03-04 | 1984-09-12 | Nippon Bussan Kk | 薬理作用を有する魚貝類エキスの製造方法 |
| JPS6287058A (ja) * | 1985-10-14 | 1987-04-21 | Osajima Kazuharu | 新規ペプチド |
| JP2005534340A (ja) * | 2002-07-29 | 2005-11-17 | アミノテック アーエス | １以上の蛋白質を含有する生材料からのペプチド／アミノ酸及び油／脂肪の回収方法、その方法により製造される産物、並びにその産物の使用 |
| JP2006507838A (ja) * | 2002-12-02 | 2006-03-09 | グリーン、アース、インダストリーズ、リミテッド、ライアビリティー、カンパニー | タンパク質含有原料の加水分解のための装置および方法ならびに得られた加水分解産物の用途 |
| WO2007069716A1 (ja) * | 2005-12-16 | 2007-06-21 | Nippon Suisan Kaisha, Ltd. | 内臓脂肪蓄積抑制作用を有する組成物 |
Non-Patent Citations (1)
| Title |
|---|
| JPN5010010634; ＷＵ ＨＵＩ-ＣＨＵＮ: ＦＯＯＤ ＲＥＳＥＡＲＣＨ ＩＮＴＥＲＮＡＴＩＯＮＡＬ Ｖ３６ Ｎ９-１０, 20030101, Ｐ９４９-９５７ * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2013168694A1 (ja) * | 2012-05-07 | 2016-01-07 | 株式会社明治 | 非糖質性エネルギー産生増強剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101815441A (zh) | 2010-08-25 |
| EP2185004A1 (en) | 2010-05-19 |
| US20110183040A1 (en) | 2011-07-28 |
| CA2695444A1 (en) | 2009-02-12 |
| US20140255592A1 (en) | 2014-09-11 |
| WO2009020394A1 (en) | 2009-02-12 |
| BRPI0814745A2 (pt) | 2014-10-07 |
| EP2185004B1 (en) | 2017-03-15 |
| CA2695444C (en) | 2017-01-17 |
| KR20100057630A (ko) | 2010-05-31 |
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