JP2011511103A - 殺菌性アルコール可溶性第四級アンモニウムポリマー - Google Patents
殺菌性アルコール可溶性第四級アンモニウムポリマー Download PDFInfo
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- JP2011511103A JP2011511103A JP2010542339A JP2010542339A JP2011511103A JP 2011511103 A JP2011511103 A JP 2011511103A JP 2010542339 A JP2010542339 A JP 2010542339A JP 2010542339 A JP2010542339 A JP 2010542339A JP 2011511103 A JP2011511103 A JP 2011511103A
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- 238000012876 topography Methods 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- RRHXZLALVWBDKH-UHFFFAOYSA-M trimethyl-[2-(2-methylprop-2-enoyloxy)ethyl]azanium;chloride Chemical compound [Cl-].CC(=C)C(=O)OCC[N+](C)(C)C RRHXZLALVWBDKH-UHFFFAOYSA-M 0.000 description 1
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 229960001296 zinc oxide Drugs 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/08—Processes
- C08G18/0804—Manufacture of polymers containing ionic or ionogenic groups
- C08G18/0809—Manufacture of polymers containing ionic or ionogenic groups containing cationic or cationogenic groups
- C08G18/0814—Manufacture of polymers containing ionic or ionogenic groups containing cationic or cationogenic groups containing ammonium groups or groups forming them
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/87—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/30—Low-molecular-weight compounds
- C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
- C08G18/3203—Polyhydroxy compounds
- C08G18/3206—Polyhydroxy compounds aliphatic
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
- C08G18/30—Low-molecular-weight compounds
- C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
- C08G18/3203—Polyhydroxy compounds
- C08G18/3218—Polyhydroxy compounds containing cyclic groups having at least one oxygen atom in the ring
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G18/00—Polymeric products of isocyanates or isothiocyanates
- C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
- C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
- C08G18/72—Polyisocyanates or polyisothiocyanates
- C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
- C08G18/76—Polyisocyanates or polyisothiocyanates cyclic aromatic
- C08G18/7614—Polyisocyanates or polyisothiocyanates cyclic aromatic containing only one aromatic ring
- C08G18/7621—Polyisocyanates or polyisothiocyanates cyclic aromatic containing only one aromatic ring being toluene diisocyanate including isomer mixtures
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/04—Oxygen-containing compounds
- C08K5/05—Alcohols; Metal alcoholates
- C08K5/053—Polyhydroxylic alcohols
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D175/00—Coating compositions based on polyureas or polyurethanes; Coating compositions based on derivatives of such polymers
- C09D175/04—Polyurethanes
- C09D175/12—Polyurethanes from compounds containing nitrogen and active hydrogen, the nitrogen atom not being part of an isocyanate group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Oncology (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Manufacturing & Machinery (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1979808P | 2008-01-08 | 2008-01-08 | |
| PCT/US2009/030437 WO2009089346A2 (en) | 2008-01-08 | 2009-01-08 | Disinfectant alcohol-soluble quaternary ammonium polymers |
Publications (2)
| Publication Number | Publication Date |
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| JP2011511103A true JP2011511103A (ja) | 2011-04-07 |
| JP2011511103A5 JP2011511103A5 (https=) | 2013-03-07 |
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| JP2010542339A Pending JP2011511103A (ja) | 2008-01-08 | 2009-01-08 | 殺菌性アルコール可溶性第四級アンモニウムポリマー |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2231761A4 (https=) |
| JP (1) | JP2011511103A (https=) |
| CN (1) | CN101970560A (https=) |
| AU (1) | AU2009204189B2 (https=) |
| BR (1) | BRPI0905679A2 (https=) |
| WO (1) | WO2009089346A2 (https=) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015500298A (ja) * | 2011-12-26 | 2015-01-05 | トライテック バイオファーマシューティカルズ カンパニー リミテッドＴｒｉｔｅｃｈ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｏ．， Ｌｔｄ． | Ｐｄｅ−５インヒビターの経皮送達を増強するための方法および改良された医薬組成物 |
| JP2017214346A (ja) * | 2015-09-30 | 2017-12-07 | 株式会社日本触媒 | 抗菌剤 |
| JP2018503598A (ja) * | 2014-10-30 | 2018-02-08 | テクスタイル−ベイスド デリバリー，インコーポレイテッド | 送達システム |
| WO2018074334A1 (ja) * | 2016-10-17 | 2018-04-26 | 株式会社日本触媒 | 洗浄剤用共重合体 |
| JP2019156763A (ja) * | 2018-03-13 | 2019-09-19 | 有限会社日本健康科学研究センター | 耐水性被膜製剤 |
| JP2020109094A (ja) * | 2020-02-26 | 2020-07-16 | 株式会社大阪製薬 | 粘稠消毒剤 |
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| WO2007080453A2 (en) | 2005-11-09 | 2007-07-19 | Klox Technologies Inc. | Teeth whitening compositions and methods |
| US20100266989A1 (en) | 2006-11-09 | 2010-10-21 | Klox Technologies Inc. | Teeth whitening compositions and methods |
| PL2352488T3 (pl) | 2008-11-07 | 2017-07-31 | Klox Technologies Inc. | Utleniająca, aktywowana światłem kompozycja do odmładzania skóry zawierająca kwas hialuronowy, glukozaminę lub alantoinę |
| HUE035716T2 (en) | 2009-07-17 | 2018-05-28 | Klox Tech Inc | Antibacterial oral composition |
| CN101828884A (zh) * | 2010-05-04 | 2010-09-15 | 江西生成卫生用品有限公司 | 宠物清洁巾 |
| CN102265894B (zh) * | 2011-06-08 | 2015-04-29 | 江中药业股份有限公司 | 一种杀灭微生物的组合物 |
| CN102246794B (zh) * | 2011-06-08 | 2015-08-19 | 江中药业股份有限公司 | 一种杀灭微生物的组合物 |
| CN102265893B (zh) * | 2011-06-08 | 2015-06-03 | 江中药业股份有限公司 | 一种抗微生物的组合物及其应用 |
| IN2014CN03706A (https=) | 2011-11-16 | 2015-10-09 | 3M Innovative Properties Co | |
| US20130281913A1 (en) | 2012-04-20 | 2013-10-24 | Klox Technologies Inc. | Biophotonic compositions and methods for providing biophotonic treatment |
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| US20140276354A1 (en) | 2013-03-14 | 2014-09-18 | Klox Technologies Inc. | Biophotonic materials and uses thereof |
| CN103333312B (zh) * | 2013-06-08 | 2015-04-22 | 浙江大学 | 具有溶胶-凝胶转变特性的温敏型抗菌嵌段聚合物及其制备方法 |
| HK1219890A1 (zh) | 2013-07-03 | 2017-04-21 | 广东科洛克生物医药集团有限公司 | 治疗不癒合伤口的组合物和方法 |
| JP2017509433A (ja) | 2014-04-01 | 2017-04-06 | クロックス テクノロジーズ インコーポレイテッドＫｌｏｘ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｉｎｃ． | 組織充填剤組成物および使用方法 |
| ES2856841T3 (es) | 2014-10-31 | 2021-09-28 | Klox Tech Inc | Fibras y medios de tela fotoactivables |
| US10834922B2 (en) | 2014-11-26 | 2020-11-17 | Microban Products Company | Surface disinfectant with residual biocidal property |
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| US11503824B2 (en) | 2016-05-23 | 2022-11-22 | Microban Products Company | Touch screen cleaning and protectant composition |
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| DE102017219459A1 (de) * | 2017-10-30 | 2019-05-02 | Röchling Automotive SE & Co. KG | Verwendung eines Kunststoffes, enthaltend antimikrobiellen Wirkstoff, zur Herstellung von Fluid speichernden oder/und führenden Kraftfahrzeug-Bauteilen |
| KR102340804B1 (ko) * | 2019-07-22 | 2021-12-17 | 주식회사 휴온스메디케어 | 클로르헥시딘 또는 이의 유도체를 포함하는 항균 지속성이 개선된 수용성 소독용 조성물 및 이를 포함하는 섬유형 소독제 |
| US20230128969A1 (en) | 2020-02-12 | 2023-04-27 | Sanitized Ag | Polyurethane foam compositions with antimicrobial properties |
| CN111297730A (zh) * | 2020-02-27 | 2020-06-19 | 诚谨健康产业有限公司 | 长效无害免洗不易燃高分子乙醇消毒剂 |
| CN111493073A (zh) * | 2020-05-28 | 2020-08-07 | 李学军 | 一种表面消毒覆膜剂及其制备方法 |
| US12332180B2 (en) | 2020-06-24 | 2025-06-17 | B/E Aerospace, Inc. | Antimicrobial surface coating formation, detection, quantification and reactivation systems and methods |
| CN116473056B (zh) * | 2023-03-21 | 2025-03-25 | 云南农业大学 | 单棕榈酸甘油、其衍生物在植物病害防治中的应用 |
| CN120590783B (zh) * | 2025-07-15 | 2025-12-09 | 广东道禾智能电子科技有限公司 | 一种抗菌手机壳及其制备工艺 |
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| US20020051754A1 (en) * | 2000-04-13 | 2002-05-02 | Schroeder Joseph D. | Anti-microbial packaging polymer and its method of use |
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| GB0505634D0 (en) * | 2005-03-18 | 2005-04-27 | Guy Allen Ltd | Antimicrobial composition |
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2009
- 2009-01-08 EP EP09701395.7A patent/EP2231761A4/en not_active Withdrawn
- 2009-01-08 BR BRPI0905679-3A patent/BRPI0905679A2/pt not_active IP Right Cessation
- 2009-01-08 WO PCT/US2009/030437 patent/WO2009089346A2/en not_active Ceased
- 2009-01-08 AU AU2009204189A patent/AU2009204189B2/en not_active Ceased
- 2009-01-08 CN CN2009801075002A patent/CN101970560A/zh active Pending
- 2009-01-08 JP JP2010542339A patent/JP2011511103A/ja active Pending
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| JPH09316369A (ja) * | 1996-03-28 | 1997-12-09 | Dainippon Printing Co Ltd | 抗菌性電離放射線硬化型塗料及び抗菌性透明フィルム |
| WO2007024973A1 (en) * | 2005-08-22 | 2007-03-01 | Quick-Med Technologies, Inc. | Disinfectant with quaternary ammonium polymers and copolymers |
| JP2009506055A (ja) * | 2005-08-22 | 2009-02-12 | クイック−メッド テクノロジーズ、インク． | 第四級アンモニウムポリマーおよびコポリマーを用いた殺菌剤 |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015500298A (ja) * | 2011-12-26 | 2015-01-05 | トライテック バイオファーマシューティカルズ カンパニー リミテッドＴｒｉｔｅｃｈ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｏ．， Ｌｔｄ． | Ｐｄｅ−５インヒビターの経皮送達を増強するための方法および改良された医薬組成物 |
| JP2018503598A (ja) * | 2014-10-30 | 2018-02-08 | テクスタイル−ベイスド デリバリー，インコーポレイテッド | 送達システム |
| US10799464B2 (en) | 2014-10-30 | 2020-10-13 | Textile-Based Delivery, Inc. | Delivery systems |
| US11633366B2 (en) | 2014-10-30 | 2023-04-25 | Textile-Based Delivery, Inc. | Delivery systems |
| US11690808B2 (en) | 2014-10-30 | 2023-07-04 | Textile-Based Delivery, Inc. | Delivery systems |
| JP2017214346A (ja) * | 2015-09-30 | 2017-12-07 | 株式会社日本触媒 | 抗菌剤 |
| WO2018074334A1 (ja) * | 2016-10-17 | 2018-04-26 | 株式会社日本触媒 | 洗浄剤用共重合体 |
| JPWO2018074334A1 (ja) * | 2016-10-17 | 2019-07-04 | 株式会社日本触媒 | 洗浄剤用共重合体 |
| JP2019156763A (ja) * | 2018-03-13 | 2019-09-19 | 有限会社日本健康科学研究センター | 耐水性被膜製剤 |
| WO2019176124A1 (ja) * | 2018-03-13 | 2019-09-19 | 有限会社 日本健康科学研究センター | 耐水性被膜製剤 |
| JP2020109094A (ja) * | 2020-02-26 | 2020-07-16 | 株式会社大阪製薬 | 粘稠消毒剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009089346A2 (en) | 2009-07-16 |
| CN101970560A (zh) | 2011-02-09 |
| BRPI0905679A2 (pt) | 2015-07-07 |
| AU2009204189A1 (en) | 2009-07-16 |
| EP2231761A2 (en) | 2010-09-29 |
| EP2231761A4 (en) | 2013-08-14 |
| WO2009089346A3 (en) | 2009-09-24 |
| AU2009204189B2 (en) | 2014-01-16 |
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