JP2011507808A5 - - Google Patents
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- Publication number
- JP2011507808A5 JP2011507808A5 JP2010537516A JP2010537516A JP2011507808A5 JP 2011507808 A5 JP2011507808 A5 JP 2011507808A5 JP 2010537516 A JP2010537516 A JP 2010537516A JP 2010537516 A JP2010537516 A JP 2010537516A JP 2011507808 A5 JP2011507808 A5 JP 2011507808A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- pharmaceutical
- cancer
- photosensitizer
- solid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 16
- 206010028980 Neoplasm Diseases 0.000 claims 8
- 201000011510 cancer Diseases 0.000 claims 8
- 239000003504 photosensitizing agent Substances 0.000 claims 8
- 239000007787 solid Substances 0.000 claims 7
- 239000000825 pharmaceutical preparation Substances 0.000 claims 6
- 229940127557 pharmaceutical product Drugs 0.000 claims 6
- ZGXJTSGNIOSYLO-UHFFFAOYSA-N 88755TAZ87 Chemical group NCC(=O)CCC(O)=O ZGXJTSGNIOSYLO-UHFFFAOYSA-N 0.000 claims 5
- 238000003745 diagnosis Methods 0.000 claims 5
- 239000003826 tablet Substances 0.000 claims 5
- 208000015181 infectious disease Diseases 0.000 claims 4
- 239000002243 precursor Substances 0.000 claims 4
- 239000002775 capsule Substances 0.000 claims 3
- 239000008188 pellet Substances 0.000 claims 3
- 238000002428 photodynamic therapy Methods 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 208000035473 Communicable disease Diseases 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 229940126589 solid medicine Drugs 0.000 claims 2
- 239000000829 suppository Substances 0.000 claims 2
- 208000024891 symptom Diseases 0.000 claims 2
- -1 5-ALA ester Chemical class 0.000 claims 1
- 241000701806 Human papillomavirus Species 0.000 claims 1
- 208000015634 Rectal Neoplasms Diseases 0.000 claims 1
- 229960002749 aminolevulinic acid Drugs 0.000 claims 1
- 239000002246 antineoplastic agent Substances 0.000 claims 1
- 125000003118 aryl group Chemical group 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 125000006165 cyclic alkyl group Chemical group 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 210000002249 digestive system Anatomy 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 210000004996 female reproductive system Anatomy 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims 1
- 229940126601 medicinal product Drugs 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008177 pharmaceutical agent Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000006187 pill Substances 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0724279.5A GB0724279D0 (en) | 2007-12-12 | 2007-12-12 | Use |
| GB0724279.5 | 2007-12-12 | ||
| PCT/GB2008/004113 WO2009074811A2 (en) | 2007-12-12 | 2008-12-12 | Use of 5-aminolevulinic acid and derivatives in a solid form for photodynamic treatment and diagnosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013192917A Division JP5863735B2 (ja) | 2007-12-12 | 2013-09-18 | 使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507808A JP2011507808A (ja) | 2011-03-10 |
| JP2011507808A5 true JP2011507808A5 (enExample) | 2012-02-16 |
| JP5686603B2 JP5686603B2 (ja) | 2015-03-18 |
Family
ID=39016493
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010537516A Expired - Fee Related JP5686603B2 (ja) | 2007-12-12 | 2008-12-12 | 使用 |
| JP2013192917A Expired - Fee Related JP5863735B2 (ja) | 2007-12-12 | 2013-09-18 | 使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013192917A Expired - Fee Related JP5863735B2 (ja) | 2007-12-12 | 2013-09-18 | 使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20110020441A1 (enExample) |
| EP (2) | EP2684573A3 (enExample) |
| JP (2) | JP5686603B2 (enExample) |
| KR (1) | KR20100095443A (enExample) |
| CN (2) | CN104306968A (enExample) |
| AU (1) | AU2008334426B2 (enExample) |
| BR (1) | BRPI0821668A2 (enExample) |
| CA (1) | CA2708137C (enExample) |
| GB (1) | GB0724279D0 (enExample) |
| NZ (2) | NZ585977A (enExample) |
| RU (2) | RU2521228C2 (enExample) |
| WO (1) | WO2009074811A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0724279D0 (en) * | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
| GB0823472D0 (en) | 2008-12-23 | 2009-01-28 | Photocure Asa | Product |
| US20120136055A1 (en) | 2009-06-11 | 2012-05-31 | Photocure Asa | Semi-solid compositions and pharmaceutical products |
| CN102802612A (zh) * | 2009-06-11 | 2012-11-28 | 光治疗Asa公司 | 含有5-氨基酮戊酸的固态组合物 |
| EP2283830A1 (en) * | 2009-07-23 | 2011-02-16 | Actogenix N.V. | Aqueous enteric capsule coating |
| DE102009028076A1 (de) * | 2009-07-29 | 2011-02-03 | Evonik Röhm Gmbh | Beschichtungsmittel zum Tauchbeschichten von Kapselhälften |
| US9107451B2 (en) | 2009-07-29 | 2015-08-18 | Evonik Röhm Gmbh | Coating composition for the dip coating of capsule halves |
| WO2011107478A1 (en) | 2010-03-01 | 2011-09-09 | Photocure Asa | Cosmetic compositions |
| WO2011161220A1 (en) | 2010-06-23 | 2011-12-29 | Photocure Asa | Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent |
| ES2620780T3 (es) * | 2010-07-09 | 2017-06-29 | Photocure Asa | Dispositivos que contienen composiciones secas para su uso en terapia fotodinámica |
| KR101254758B1 (ko) * | 2011-02-28 | 2013-04-15 | 부산대학교병원 | 광역동치료의 광증감제로 사용하기 위한 이디티에이를 이용한 아미노레불리닉산 테트라머 |
| RU2454255C1 (ru) * | 2011-05-30 | 2012-06-27 | Виктор Александрович Борисов | Способ фотодинамической терапии злокачественных новообразований |
| US9492682B2 (en) * | 2011-09-14 | 2016-11-15 | Medicis Pharmaceutical Corporation | Combination therapy with low dosage strength imiquimod and photodynamic therapy to treat actinic keratosis |
| AU2013298525B2 (en) * | 2012-08-03 | 2017-12-14 | Photocure Asa | Compounds |
| US20140067024A1 (en) | 2012-08-30 | 2014-03-06 | Photocure Asa | Dual panel photodynamic therapy lamp |
| GB201221123D0 (en) | 2012-11-23 | 2013-01-09 | Photocure As | Device for photodynamic treatment |
| EP2968128A4 (en) * | 2013-03-12 | 2016-11-16 | Applied Biores Inc | CHELATING COFFEE FOR IMPROVED DRUG DISPERSION |
| JP6352912B2 (ja) * | 2013-06-21 | 2018-07-04 | 国立大学法人 岡山大学 | 異常活性化細胞検出による悪性腫瘍の検査方法および異常活性化細胞除去環流返血治療装置 |
| US20150364550A1 (en) * | 2014-06-16 | 2015-12-17 | Infineon Technologies Ag | Optimized layer for semiconductor |
| CN104306971B (zh) * | 2014-10-29 | 2017-02-15 | 青岛大学附属医院 | 一种配合光动力疗法抗宫颈癌的药物组合物 |
| US10603508B2 (en) | 2015-10-15 | 2020-03-31 | Dusa Pharmaceuticals, Inc. | Adjustable illuminators and methods for photodynamic therapy and diagnosis |
| PL3362145T3 (pl) | 2015-10-15 | 2021-07-19 | Dusa Pharmaceuticals, Inc. | Regulowany oświetlacz do terapii fotodynamicznej i diagnostyki |
| DK3389716T3 (da) | 2015-12-17 | 2022-04-11 | Photocure Asa | Fremgangsmåde til fotodynamisk terapi (pdt) for blærekræft |
| GB201522398D0 (en) | 2015-12-18 | 2016-02-03 | Photocure As | Device for photodynamic therapy |
| GB2546128A (en) * | 2016-09-28 | 2017-07-12 | Photocure Asa | Pharamaceutical compositions comprising hexaminolevulinic acid and methods of using the same |
| CN107434753A (zh) * | 2017-07-26 | 2017-12-05 | 南京大学 | 5‑氨基乙酰丙酸及其衍生物的泡腾片及其制备方法 |
| CN107854471A (zh) * | 2017-10-26 | 2018-03-30 | 郭裴哲 | 一种治疗宫颈糜烂的药物制剂及用途 |
| CN107812190A (zh) * | 2017-11-10 | 2018-03-20 | 中国医学科学院生物医学工程研究所 | 一种用于直肠肿瘤治疗的光动力试剂盒及制备方法 |
| US10357567B1 (en) * | 2018-01-12 | 2019-07-23 | Dusa Pharmaceuticals, Inc. | Methods for photodynamic therapy |
| CN108079298B (zh) * | 2018-01-26 | 2021-05-25 | 南方医科大学南方医院 | 一种经皮光动力药物5-氨基酮戊酸己酯盐酸盐醇质体及其制备方法和应用 |
| GB201905940D0 (en) * | 2019-04-29 | 2019-06-12 | Intract Pharma Ltd | 5-aminolevulinic acid for the local treatment of inflammatory bowel disease |
| KR102265592B1 (ko) * | 2020-10-29 | 2021-06-17 | 김진왕 | 5-아미노레불린산 수화염화물을 포함하는 조성물 |
| WO2023079513A1 (en) * | 2021-11-05 | 2023-05-11 | Dusa Pharmaceuticals, Inc. | Photodynamic therapy illuminator devices and methods |
| AU2023374228A1 (en) * | 2022-11-04 | 2025-05-15 | Sun Pharmaceutical Industries, Inc. | Photodynamic therapy methods |
| CN115671059B (zh) * | 2022-11-17 | 2024-06-11 | 兆科药业（合肥）有限公司 | 一种盐酸氨酮戊酸冻干制剂及制备方法 |
| CN115998904A (zh) * | 2023-01-17 | 2023-04-25 | 武汉理工大学 | 一种光敏剂联合抗生素智能抗菌水凝胶及其制备方法和应用 |
| CN116271547A (zh) * | 2023-03-17 | 2023-06-23 | 丹东英发科技开发有限公司 | 高导光性能之医用导光凝胶和其制备方法 |
| CN119264000B (zh) * | 2024-09-30 | 2025-10-14 | 广东溢多利生物科技股份有限公司 | 一种5-ala液体的稳定剂 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6133111A (ja) * | 1984-06-18 | 1986-02-17 | Hisamitsu Pharmaceut Co Inc | 直腸投与製剤 |
| US4765978A (en) * | 1986-12-16 | 1988-08-23 | Schering Corporation | Novel vaginal suppository |
| US5234940A (en) * | 1989-07-28 | 1993-08-10 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
| US5955490A (en) * | 1989-07-28 | 1999-09-21 | Queen's University At Kingston | Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins |
| US5079262A (en) * | 1989-07-28 | 1992-01-07 | Queen's University At Kingston | Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid |
| US5422093A (en) * | 1989-07-28 | 1995-06-06 | Queen's University | Photochemotherapeutic method using 5-aminolevulinic acid and precursors thereof |
| JP3181062B2 (ja) * | 1991-01-31 | 2001-07-03 | 帝國製薬株式会社 | 下部消化管崩壊経口製剤 |
| JPH05213752A (ja) * | 1992-02-06 | 1993-08-24 | Fujisawa Asutora Kk | 坐 剤 |
| GB9504948D0 (en) * | 1995-03-10 | 1995-04-26 | Norwegian Radium Hospital Rese | Compounds |
| US6992107B1 (en) * | 1995-03-10 | 2006-01-31 | Photocure Asa | Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy |
| US7530461B2 (en) * | 1995-03-10 | 2009-05-12 | Photocure Asa | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy |
| CZ291132B6 (cs) * | 1995-03-10 | 2002-12-11 | Photocure Asa | Estery kyselin 5-aminolevulových a farmaceutický prostředek s jejich obsahem |
| GB9700396D0 (en) * | 1997-01-10 | 1997-02-26 | Photocure As | Photochemotherapeutic compositions |
| JP4162735B2 (ja) * | 1997-02-26 | 2008-10-08 | 久光製薬株式会社 | セロトニン受容体拮抗薬含有直腸投与製剤 |
| JPH1112197A (ja) * | 1997-06-18 | 1999-01-19 | Cosmo Sogo Kenkyusho:Kk | 悪性腫瘍診断剤及び治療剤 |
| AU5486899A (en) * | 1998-08-13 | 2000-03-06 | Cima Labs, Inc. | Microemulsions as solid dosage forms for oral administration |
| JP3614305B2 (ja) * | 1998-08-28 | 2005-01-26 | 株式会社オーバル | 流量計の誤計数防止装置 |
| DE10003620A1 (de) * | 2000-01-28 | 2001-08-02 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Formulierung in nichtwässrigen Lösungsmitteln |
| DE10034673C1 (de) * | 2000-07-17 | 2002-04-25 | Medac Klinische Spezialpraep | Dermales Applikationssystem für Aminolävulinsäure und seine Verwendung |
| GB0018527D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Composition |
| GB0018528D0 (en) * | 2000-07-27 | 2000-09-13 | Photocure Asa | Compounds |
| WO2002013788A1 (en) * | 2000-08-16 | 2002-02-21 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Topical aminolevulinic acid-photodynamic therapy for acne vulgaris |
| US8101209B2 (en) * | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
| US7264629B2 (en) * | 2001-11-09 | 2007-09-04 | Qlt, Inc. | Photodynamic therapy for the treatment of hair loss |
| US6723750B2 (en) * | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
| US20040171601A1 (en) * | 2002-07-31 | 2004-09-02 | Dai Fukumura | Photodynamic and sonodynamic therapy |
| GB0315671D0 (en) * | 2003-07-04 | 2003-08-13 | Chelsea And Westminster Nhs Tr | Improvements in or relating to organic compounds |
| US20070225518A1 (en) * | 2006-03-22 | 2007-09-27 | Zvi Malik | 5-Aminolevulinic acid salts and their use |
| GB0609809D0 (en) * | 2006-05-17 | 2006-06-28 | Photocure Asa | Product |
| GB0724279D0 (en) * | 2007-12-12 | 2008-01-23 | Photocure Asa | Use |
-
2007
- 2007-12-12 GB GBGB0724279.5A patent/GB0724279D0/en not_active Ceased
-
2008
- 2008-12-12 NZ NZ585977A patent/NZ585977A/en not_active IP Right Cessation
- 2008-12-12 US US12/808,177 patent/US20110020441A1/en not_active Abandoned
- 2008-12-12 NZ NZ600028A patent/NZ600028A/xx not_active IP Right Cessation
- 2008-12-12 BR BRPI0821668-1A patent/BRPI0821668A2/pt not_active IP Right Cessation
- 2008-12-12 AU AU2008334426A patent/AU2008334426B2/en not_active Ceased
- 2008-12-12 CN CN201410411870.8A patent/CN104306968A/zh active Pending
- 2008-12-12 EP EP13186756.6A patent/EP2684573A3/en not_active Withdrawn
- 2008-12-12 RU RU2010123086/15A patent/RU2521228C2/ru not_active IP Right Cessation
- 2008-12-12 WO PCT/GB2008/004113 patent/WO2009074811A2/en not_active Ceased
- 2008-12-12 CA CA2708137A patent/CA2708137C/en not_active Expired - Fee Related
- 2008-12-12 CN CN200880120455XA patent/CN101896203A/zh active Pending
- 2008-12-12 JP JP2010537516A patent/JP5686603B2/ja not_active Expired - Fee Related
- 2008-12-12 KR KR1020107012789A patent/KR20100095443A/ko not_active Ceased
- 2008-12-12 EP EP08860052A patent/EP2231188A2/en not_active Withdrawn
-
2013
- 2013-09-18 JP JP2013192917A patent/JP5863735B2/ja not_active Expired - Fee Related
-
2014
- 2014-04-02 RU RU2014112548/15A patent/RU2014112548A/ru not_active Application Discontinuation
- 2014-07-17 US US14/333,979 patent/US20150031761A1/en not_active Abandoned
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