JP2011505414A5 - - Google Patents

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Publication number
JP2011505414A5
JP2011505414A5 JP2010536523A JP2010536523A JP2011505414A5 JP 2011505414 A5 JP2011505414 A5 JP 2011505414A5 JP 2010536523 A JP2010536523 A JP 2010536523A JP 2010536523 A JP2010536523 A JP 2010536523A JP 2011505414 A5 JP2011505414 A5 JP 2011505414A5
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JP
Japan
Prior art keywords
peptide
composition
subject
item
factor viii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010536523A
Other languages
English (en)
Japanese (ja)
Other versions
JP5501245B2 (ja
JP2011505414A (ja
Filing date
Publication date
Priority claimed from GBGB0723712.6A external-priority patent/GB0723712D0/en
Application filed filed Critical
Publication of JP2011505414A publication Critical patent/JP2011505414A/ja
Publication of JP2011505414A5 publication Critical patent/JP2011505414A5/ja
Application granted granted Critical
Publication of JP5501245B2 publication Critical patent/JP5501245B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010536523A 2007-12-04 2008-12-03 Fviiiペプチドおよび血友病を寛容化することにおけるその使用 Expired - Fee Related JP5501245B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0723712.6A GB0723712D0 (en) 2007-12-04 2007-12-04 Peptides
GB0723712.6 2007-12-04
PCT/GB2008/003996 WO2009071886A1 (en) 2007-12-04 2008-12-03 Fviii peptides and their use in tolerising haemophiliacs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014023217A Division JP6063402B2 (ja) 2007-12-04 2014-02-10 Fviiiペプチドおよび血友病を寛容化することにおけるその使用

Publications (3)

Publication Number Publication Date
JP2011505414A JP2011505414A (ja) 2011-02-24
JP2011505414A5 true JP2011505414A5 (https=) 2012-10-25
JP5501245B2 JP5501245B2 (ja) 2014-05-21

Family

ID=38982965

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2010536523A Expired - Fee Related JP5501245B2 (ja) 2007-12-04 2008-12-03 Fviiiペプチドおよび血友病を寛容化することにおけるその使用
JP2014023217A Expired - Fee Related JP6063402B2 (ja) 2007-12-04 2014-02-10 Fviiiペプチドおよび血友病を寛容化することにおけるその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014023217A Expired - Fee Related JP6063402B2 (ja) 2007-12-04 2014-02-10 Fviiiペプチドおよび血友病を寛容化することにおけるその使用

Country Status (25)

Country Link
US (1) US8445448B2 (https=)
EP (1) EP2227488B3 (https=)
JP (2) JP5501245B2 (https=)
KR (1) KR101519840B1 (https=)
CN (2) CN101889024B (https=)
AU (1) AU2008332968B2 (https=)
BR (1) BRPI0820143A2 (https=)
CA (2) CA3005013C (https=)
CY (1) CY1115168T1 (https=)
DK (1) DK2227488T6 (https=)
EA (1) EA019370B1 (https=)
EC (1) ECSP10010327A (https=)
ES (1) ES2458315T7 (https=)
GB (1) GB0723712D0 (https=)
HR (1) HRP20140344T4 (https=)
IL (1) IL205780A (https=)
MX (1) MX2010006084A (https=)
MY (1) MY150995A (https=)
NZ (1) NZ585217A (https=)
PL (1) PL2227488T6 (https=)
PT (1) PT2227488E (https=)
SI (1) SI2227488T1 (https=)
UA (1) UA101003C2 (https=)
WO (1) WO2009071886A1 (https=)
ZA (1) ZA201002997B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102764425B (zh) 2000-08-21 2015-11-25 阿皮托普技术(布里斯托尔)有限公司 肽选择方法
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII
EP2300497B1 (en) * 2008-06-24 2012-08-08 Octapharma AG A process of purifying coagulation factor viii
GB0908515D0 (en) * 2009-05-18 2009-06-24 Apitope Technology Bristol Ltd Peptide
CA2765657A1 (en) * 2009-06-16 2010-12-23 Tokai University Anti-gram-negative bacteria agent
EP2632479B1 (en) * 2010-10-27 2017-06-14 Baxalta GmbH Fviii peptides for immune tolerance induction and immunodiagnostics
EA038705B1 (ru) 2012-01-12 2021-10-07 Биовератив Терапьютикс Инк. Способы снижения иммуногенности фактора свёртывания крови viii у пациентов, получающих лечение фактором viii
EA036483B1 (ru) * 2012-11-12 2020-11-16 Эпитоп Интернэшнл Нв Пептиды, способные индуцировать толерантность к рекомбинантному fviii, содержащая их композиция, их применение и способ лечения гемофилии
GB201314052D0 (en) * 2013-08-06 2013-09-18 Apitope Int Nv Peptides
EP4212547A1 (en) 2015-12-03 2023-07-19 Juno Therapeutics, Inc. Modified chimeric receptors and related compositions and methods
JP2019536794A (ja) 2016-12-02 2019-12-19 バイオベラティブ セラピューティクス インコーポレイテッド 凝固因子に対する免疫寛容を誘導する方法
US12077607B2 (en) * 2021-09-23 2024-09-03 University Of Utah Research Foundation Functional and therapeutic effects of PAR4 cleavage by cathepsin G

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE902211A1 (en) * 1989-06-20 1991-01-16 Scripps Clinic Res The phospholipid binding domain of factor viii
WO1998031394A2 (en) * 1997-01-22 1998-07-23 Board Of Regents, The University Of Texas System Tissue factor methods and compositions for coagulation and tumor treatment
CN102764425B (zh) * 2000-08-21 2015-11-25 阿皮托普技术(布里斯托尔)有限公司 肽选择方法
AU2002249779A1 (en) * 2000-12-01 2002-08-12 Regents Of The University Of Minnesota Method to treat hemophilia
CN100522242C (zh) * 2001-02-19 2009-08-05 默克专利有限公司 具有降低的免疫原性的人工蛋白质
WO2002098454A2 (en) 2001-05-31 2002-12-12 D. Collen Research Foundation Vzw Onderwijsen Navorsing Campus Gasthuisberg K.U. Leuven Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
WO2003087161A1 (en) 2002-04-18 2003-10-23 Merck Patent Gmbh Modified factor viii
HUE027902T2 (en) * 2004-02-09 2016-11-28 Human Genome Sciences Inc Corp Service Company Albumin fusion proteins
WO2006003183A1 (de) 2004-07-02 2006-01-12 Alois Jungbauer Peptide zur blockierung von fviii-inhibitoren
IL229645A0 (en) * 2013-11-26 2014-03-31 Omrix Biopharmaceuticals Ltd A dry bandage containing thrombin and pectin

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