KR101519840B1 - Ｆⅷ 펩타이드 및 혈우병 환자 내성화시 그의 용도 - Google Patents

Ｆⅷ 펩타이드 및 혈우병 환자 내성화시 그의 용도 Download PDF

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Publication number
KR101519840B1
KR101519840B1 KR1020107011743A KR20107011743A KR101519840B1 KR 101519840 B1 KR101519840 B1 KR 101519840B1 KR 1020107011743 A KR1020107011743 A KR 1020107011743A KR 20107011743 A KR20107011743 A KR 20107011743A KR 101519840 B1 KR101519840 B1 KR 101519840B1
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arg
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Korean (ko)
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KR20100087346A (ko
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데이비드 레이트
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아피토프 인터내셔날 엔브이
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020107011743A 2007-12-04 2008-12-03 Ｆⅷ 펩타이드 및 혈우병 환자 내성화시 그의 용도 Expired - Fee Related KR101519840B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0723712.6A GB0723712D0 (en) 2007-12-04 2007-12-04 Peptides
GB0723712.6 2007-12-04
PCT/GB2008/003996 WO2009071886A1 (en) 2007-12-04 2008-12-03 Fviii peptides and their use in tolerising haemophiliacs

Publications (2)

Publication Number Publication Date
KR20100087346A KR20100087346A (ko) 2010-08-04
KR101519840B1 true KR101519840B1 (ko) 2015-05-18

Family

ID=38982965

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107011743A Expired - Fee Related KR101519840B1 (ko) 2007-12-04 2008-12-03 Ｆⅷ 펩타이드 및 혈우병 환자 내성화시 그의 용도

Country Status (25)

Country Link
US (1) US8445448B2 (https=)
EP (1) EP2227488B3 (https=)
JP (2) JP5501245B2 (https=)
KR (1) KR101519840B1 (https=)
CN (2) CN101889024B (https=)
AU (1) AU2008332968B2 (https=)
BR (1) BRPI0820143A2 (https=)
CA (2) CA3005013C (https=)
CY (1) CY1115168T1 (https=)
DK (1) DK2227488T6 (https=)
EA (1) EA019370B1 (https=)
EC (1) ECSP10010327A (https=)
ES (1) ES2458315T7 (https=)
GB (1) GB0723712D0 (https=)
HR (1) HRP20140344T4 (https=)
IL (1) IL205780A (https=)
MX (1) MX2010006084A (https=)
MY (1) MY150995A (https=)
NZ (1) NZ585217A (https=)
PL (1) PL2227488T6 (https=)
PT (1) PT2227488E (https=)
SI (1) SI2227488T1 (https=)
UA (1) UA101003C2 (https=)
WO (1) WO2009071886A1 (https=)
ZA (1) ZA201002997B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1731912T1 (sl) 2000-08-21 2014-05-30 Apitope Technology (Bristol) Limited Postopek izbire peptida
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII
KR20160104740A (ko) * 2008-06-24 2016-09-05 옥타파마 아게 응고 인자 ｖｉｉｉ을 정제하는 방법
GB0908515D0 (en) * 2009-05-18 2009-06-24 Apitope Technology Bristol Ltd Peptide
SG176783A1 (en) * 2009-06-16 2012-01-30 Univ Tokai Anti-gram-negative bacteria agent
BR112013010362A2 (pt) * 2010-10-27 2016-08-02 Baxter Healthcare Sa métodos para induzir uma tolerância imune a fviii, para fazer um peptídeo fviii, e para identificar uma célula t específica de peptídeo fvii, peptídeo, composição, e, proteína de fusão
EP3970737A1 (en) 2012-01-12 2022-03-23 Bioverativ Therapeutics Inc. Reducing immunogenicity against factor viii in individuals undergoing factor viii therapy
RS56069B1 (sr) * 2012-11-12 2017-10-31 Apitope Int Nv Faktor viii-izvedenih peptida za upotrebu u lečenju hemofilije a
GB201314052D0 (en) * 2013-08-06 2013-09-18 Apitope Int Nv Peptides
CN108884140B (zh) 2015-12-03 2022-10-25 朱诺治疗学股份有限公司 修饰的嵌合受体及相关组合物和方法
CN110520149A (zh) 2016-12-02 2019-11-29 比奥维拉迪维治疗股份有限公司 诱导对凝血因子的免疫耐受性的方法
US12077607B2 (en) * 2021-09-23 2024-09-03 University Of Utah Research Foundation Functional and therapeutic effects of PAR4 cleavage by cathepsin G

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000070389A (ko) * 1997-01-22 2000-11-25 파라비 레이 응고 및 종양 치료용 조직 인자 방법 및 조성물
WO2002060917A2 (en) * 2000-12-01 2002-08-08 Regents Of The University Of Minnesota Method to treat hemophilia
KR20070016119A (ko) * 2004-02-09 2007-02-07 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990015615A1 (en) 1989-06-20 1990-12-27 Scripps Clinic And Research Foundation The phospholipid binding domain of factor viii
SI1731912T1 (sl) * 2000-08-21 2014-05-30 Apitope Technology (Bristol) Limited Postopek izbire peptida
US7189830B2 (en) * 2001-02-19 2007-03-13 Merck Patent Gmbh Anti-KSA/IL-2 fusion proteins with reduced immunogenicity
AU2002312660A1 (en) 2001-05-31 2002-12-16 D. Collen Research Foundation Vzw Onderwijsen Navorsing Campus Gasthuisberg K.U. Leuven Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
JP2005538694A (ja) * 2002-04-18 2005-12-22 メルク　パテント　ゲゼルシャフト　ミット　ベシュレンクテル　ハフトング 修飾されたｖｉｉｉ因子
WO2006003183A1 (de) 2004-07-02 2006-01-12 Alois Jungbauer Peptide zur blockierung von fviii-inhibitoren
IL229645A0 (en) * 2013-11-26 2014-03-31 Omrix Biopharmaceuticals Ltd A dry bandage containing thrombin and pectin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000070389A (ko) * 1997-01-22 2000-11-25 파라비 레이 응고 및 종양 치료용 조직 인자 방법 및 조성물
WO2002060917A2 (en) * 2000-12-01 2002-08-08 Regents Of The University Of Minnesota Method to treat hemophilia
WO2002060917A3 (en) 2000-12-01 2003-01-30 Univ Minnesota Method to treat hemophilia
KR20070016119A (ko) * 2004-02-09 2007-02-07 휴먼 게놈 사이언시즈, 인코포레이티드 알부민 융합 단백질

Also Published As

Publication number Publication date
ES2458315T3 (es) 2014-04-30
AU2008332968B2 (en) 2014-03-20
KR20100087346A (ko) 2010-08-04
JP5501245B2 (ja) 2014-05-21
EA019370B1 (ru) 2014-03-31
US8445448B2 (en) 2013-05-21
PT2227488E (pt) 2014-04-21
UA101003C2 (uk) 2013-02-25
EP2227488B1 (en) 2014-01-22
MX2010006084A (es) 2010-06-23
DK2227488T3 (da) 2014-04-22
IL205780A (en) 2015-06-30
EP2227488B3 (en) 2014-11-19
JP6063402B2 (ja) 2017-01-18
MY150995A (en) 2014-03-31
GB0723712D0 (en) 2008-01-16
CA3005013A1 (en) 2009-06-11
WO2009071886A1 (en) 2009-06-11
JP2011505414A (ja) 2011-02-24
HRP20140344T4 (hr) 2015-07-31
AU2008332968A1 (en) 2009-06-11
CA3005013C (en) 2021-11-16
EP2227488A1 (en) 2010-09-15
DK2227488T6 (en) 2015-02-16
US20100323966A1 (en) 2010-12-23
HRP20140344T1 (en) 2014-05-09
CN103709234B (zh) 2017-01-18
JP2014088440A (ja) 2014-05-15
ZA201002997B (en) 2011-07-27
ECSP10010327A (es) 2010-09-30
CN101889024B (zh) 2014-04-23
SI2227488T1 (sl) 2014-06-30
CN101889024A (zh) 2010-11-17
IL205780A0 (en) 2010-11-30
CY1115168T1 (el) 2016-12-14
PL2227488T6 (pl) 2015-04-30
CA2707559A1 (en) 2009-06-11
BRPI0820143A2 (pt) 2015-05-12
HK1144292A1 (en) 2011-02-11
EA201070681A1 (ru) 2010-10-29
NZ585217A (en) 2012-11-30
PL2227488T3 (pl) 2014-07-31
CA2707559C (en) 2018-07-03
CN103709234A (zh) 2014-04-09
ES2458315T7 (es) 2015-02-18

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