HRP20140344T4 - Fviii peptidi i njihova uporaba u lijeäśenju hemofilije - Google Patents

Fviii peptidi i njihova uporaba u lijeäśenju hemofilije Download PDF

Info

Publication number
HRP20140344T4
HRP20140344T4 HRP20140344TT HRP20140344T HRP20140344T4 HR P20140344 T4 HRP20140344 T4 HR P20140344T4 HR P20140344T T HRP20140344T T HR P20140344TT HR P20140344 T HRP20140344 T HR P20140344T HR P20140344 T4 HRP20140344 T4 HR P20140344T4
Authority
HR
Croatia
Prior art keywords
peptide
subject
preparation according
treatment
preparation
Prior art date
Application number
HRP20140344TT
Other languages
English (en)
Croatian (hr)
Inventor
David Wraith
Original Assignee
Apitope International Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apitope International Nv filed Critical Apitope International Nv
Publication of HRP20140344T1 publication Critical patent/HRP20140344T1/hr
Publication of HRP20140344T4 publication Critical patent/HRP20140344T4/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HRP20140344TT 2007-12-04 2008-12-03 Fviii peptidi i njihova uporaba u lijeäśenju hemofilije HRP20140344T4 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0723712.6A GB0723712D0 (en) 2007-12-04 2007-12-04 Peptides
EP08855772.3A EP2227488B3 (en) 2007-12-04 2008-12-03 Fviii peptides and their use in tolerising haemophiliacs
PCT/GB2008/003996 WO2009071886A1 (en) 2007-12-04 2008-12-03 Fviii peptides and their use in tolerising haemophiliacs

Publications (2)

Publication Number Publication Date
HRP20140344T1 HRP20140344T1 (en) 2014-05-09
HRP20140344T4 true HRP20140344T4 (hr) 2015-07-31

Family

ID=38982965

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20140344TT HRP20140344T4 (hr) 2007-12-04 2008-12-03 Fviii peptidi i njihova uporaba u lijeäśenju hemofilije

Country Status (25)

Country Link
US (1) US8445448B2 (https=)
EP (1) EP2227488B3 (https=)
JP (2) JP5501245B2 (https=)
KR (1) KR101519840B1 (https=)
CN (2) CN101889024B (https=)
AU (1) AU2008332968B2 (https=)
BR (1) BRPI0820143A2 (https=)
CA (2) CA3005013C (https=)
CY (1) CY1115168T1 (https=)
DK (1) DK2227488T6 (https=)
EA (1) EA019370B1 (https=)
EC (1) ECSP10010327A (https=)
ES (1) ES2458315T7 (https=)
GB (1) GB0723712D0 (https=)
HR (1) HRP20140344T4 (https=)
IL (1) IL205780A (https=)
MX (1) MX2010006084A (https=)
MY (1) MY150995A (https=)
NZ (1) NZ585217A (https=)
PL (1) PL2227488T6 (https=)
PT (1) PT2227488E (https=)
SI (1) SI2227488T1 (https=)
UA (1) UA101003C2 (https=)
WO (1) WO2009071886A1 (https=)
ZA (1) ZA201002997B (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102764425B (zh) 2000-08-21 2015-11-25 阿皮托普技术(布里斯托尔)有限公司 肽选择方法
GB0801513D0 (en) * 2008-01-28 2008-03-05 Circassia Ltd Peptides from factor VIII
EP2300497B1 (en) * 2008-06-24 2012-08-08 Octapharma AG A process of purifying coagulation factor viii
GB0908515D0 (en) * 2009-05-18 2009-06-24 Apitope Technology Bristol Ltd Peptide
CA2765657A1 (en) * 2009-06-16 2010-12-23 Tokai University Anti-gram-negative bacteria agent
EP2632479B1 (en) * 2010-10-27 2017-06-14 Baxalta GmbH Fviii peptides for immune tolerance induction and immunodiagnostics
EA038705B1 (ru) 2012-01-12 2021-10-07 Биовератив Терапьютикс Инк. Способы снижения иммуногенности фактора свёртывания крови viii у пациентов, получающих лечение фактором viii
EA036483B1 (ru) * 2012-11-12 2020-11-16 Эпитоп Интернэшнл Нв Пептиды, способные индуцировать толерантность к рекомбинантному fviii, содержащая их композиция, их применение и способ лечения гемофилии
GB201314052D0 (en) * 2013-08-06 2013-09-18 Apitope Int Nv Peptides
EP4212547A1 (en) 2015-12-03 2023-07-19 Juno Therapeutics, Inc. Modified chimeric receptors and related compositions and methods
JP2019536794A (ja) 2016-12-02 2019-12-19 バイオベラティブ セラピューティクス インコーポレイテッド 凝固因子に対する免疫寛容を誘導する方法
US12077607B2 (en) * 2021-09-23 2024-09-03 University Of Utah Research Foundation Functional and therapeutic effects of PAR4 cleavage by cathepsin G

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE902211A1 (en) * 1989-06-20 1991-01-16 Scripps Clinic Res The phospholipid binding domain of factor viii
WO1998031394A2 (en) * 1997-01-22 1998-07-23 Board Of Regents, The University Of Texas System Tissue factor methods and compositions for coagulation and tumor treatment
CN102764425B (zh) * 2000-08-21 2015-11-25 阿皮托普技术(布里斯托尔)有限公司 肽选择方法
AU2002249779A1 (en) * 2000-12-01 2002-08-12 Regents Of The University Of Minnesota Method to treat hemophilia
CN100522242C (zh) * 2001-02-19 2009-08-05 默克专利有限公司 具有降低的免疫原性的人工蛋白质
WO2002098454A2 (en) 2001-05-31 2002-12-12 D. Collen Research Foundation Vzw Onderwijsen Navorsing Campus Gasthuisberg K.U. Leuven Recombinant molecules with reduced immunogenicity, methods and intermediates for obtaining them and their use in pharmaceutical compositions and diagnostic tools
WO2003087161A1 (en) 2002-04-18 2003-10-23 Merck Patent Gmbh Modified factor viii
HUE027902T2 (en) * 2004-02-09 2016-11-28 Human Genome Sciences Inc Corp Service Company Albumin fusion proteins
WO2006003183A1 (de) 2004-07-02 2006-01-12 Alois Jungbauer Peptide zur blockierung von fviii-inhibitoren
IL229645A0 (en) * 2013-11-26 2014-03-31 Omrix Biopharmaceuticals Ltd A dry bandage containing thrombin and pectin

Also Published As

Publication number Publication date
NZ585217A (en) 2012-11-30
DK2227488T6 (en) 2015-02-16
GB0723712D0 (en) 2008-01-16
JP5501245B2 (ja) 2014-05-21
IL205780A0 (en) 2010-11-30
EA019370B1 (ru) 2014-03-31
ES2458315T3 (es) 2014-04-30
WO2009071886A1 (en) 2009-06-11
CA3005013A1 (en) 2009-06-11
KR101519840B1 (ko) 2015-05-18
EP2227488A1 (en) 2010-09-15
CA2707559A1 (en) 2009-06-11
AU2008332968B2 (en) 2014-03-20
CA3005013C (en) 2021-11-16
ECSP10010327A (es) 2010-09-30
PL2227488T6 (pl) 2015-04-30
SI2227488T1 (sl) 2014-06-30
US8445448B2 (en) 2013-05-21
MY150995A (en) 2014-03-31
MX2010006084A (es) 2010-06-23
EP2227488B3 (en) 2014-11-19
ES2458315T7 (es) 2015-02-18
JP6063402B2 (ja) 2017-01-18
US20100323966A1 (en) 2010-12-23
PT2227488E (pt) 2014-04-21
PL2227488T3 (pl) 2014-07-31
CN103709234B (zh) 2017-01-18
JP2011505414A (ja) 2011-02-24
HRP20140344T1 (en) 2014-05-09
HK1144292A1 (en) 2011-02-11
AU2008332968A1 (en) 2009-06-11
BRPI0820143A2 (pt) 2015-05-12
KR20100087346A (ko) 2010-08-04
EP2227488B1 (en) 2014-01-22
IL205780A (en) 2015-06-30
EA201070681A1 (ru) 2010-10-29
CY1115168T1 (el) 2016-12-14
CN103709234A (zh) 2014-04-09
ZA201002997B (en) 2011-07-27
JP2014088440A (ja) 2014-05-15
CA2707559C (en) 2018-07-03
UA101003C2 (uk) 2013-02-25
CN101889024B (zh) 2014-04-23
DK2227488T3 (da) 2014-04-22
CN101889024A (zh) 2010-11-17

Similar Documents

Publication Publication Date Title
HRP20140344T4 (hr) Fviii peptidi i njihova uporaba u lijeäśenju hemofilije
ATE534660T1 (de) Peptidsequenzen und zusammensetzungen
IL222880A (en) Peptides and their use in the treatment and diagnosis of diseases and pharmaceutical preparations containing them
WO2008118017A3 (en) Prame derived peptides and immunogenic compositions comprising these
CR11042A (es) Anticuerpos ox40 antagonistas y su uso en el tratamiento de enfermedades inflamatorias y autoinmunes
SI2341142T1 (sl) HLA-A*1101-omejen WT1 peptid in farmacevtski sestavek, ki ga vsebuje
CY1116828T1 (el) Πεπτιδια για απευαισθητοποιηση απο αλλεργιογονα
FR2900573B1 (fr) Nouvelles compositions cosmetiques renfermant au moins un peptide contenant au moins un cycle aromatique bloque
DK3120862T3 (da) Antimikrobielt peptid og sammensætninger deraf
MX2009004147A (es) Vacunas de peptido para canceres que expresan polipeptidos mphosph1 o depdc1.
DE602006009268D1 (de) ,4,-tetramethyl-1, 3-cyclobutandiol und 1,4- cyclohexandimethanol gebildete polyesterzusammensetzungen
EP1791553A4 (en) COMPOSITIONS FOR THE DELIVERY OF PEPTIDE YY AND PYY AGONISTS
EP1988163A4 (en) HLA-A * 3303-RESTRICTED WT1-PEPTIDE, AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF
BR112012011332A2 (pt) agentes direcionados para gadd45beta
CL2012001710A1 (es) Anticuerpo aislado que se enlaza selectivamente a hepcidina-25 humana y cuyas hcvr y lcvr tienen las secuencias de aminoácido sec id nos:150 y 124; polinucleótido, vector; célula hospedadora; uso en el tratamiento y/o prevención de anemia; procedimiento de producción y composición farmacéutica (div. de sol. 3190-08).
IL210364A (en) Beta-amyloid peptide cyclic peptide analogue and its use in the treatment and diagnosis of neurodegenerative diseases or conditions
EP1874334A4 (en) COMPOSITIONS WITH BETA 2-GLYCOPROTEIN I-PEPTIDES FOR THE PREVENTION AND / OR TREATMENT OF VASCULAR DISEASES
CL2007003038A1 (es) Compuestos derivados de 2-fenil-6-aminocarbonil-pirimidina; composicion farmaceutica; y uso en el tratamiento de trastornos vasculares oclusivos.
HUE038953T2 (hu) Peptid szekvenciák és készítmények anopheles gambiae-fajból
HRP20141182T1 (hr) Fviii-izvedeni peptidi i njihova upotreba za izazivanje tolerancije kod hemofiliäśara
EP2119373A4 (en) SWEET CELLUS COMPOSITIONS CONTAINING LARGE AMOUNTS OF AMINO ACIDS AND YEAST FOR THEIR ENVIRONMENT
CL2008002353A1 (es) Compuestos derivados de 7h-indolo[2,1-a][2]benzazepina; composicion farmaceutica; y uso en el tratamiento de la hepatitis c.
DK2209527T3 (da) Farmaceutiske sammensætninger omfattende L-acidophilus og Bifidobacterium lactis til anvendelse i behandlingen af funktionel tarmsygdom
ATE457736T1 (de) Zusammensetzung aus einem pulmonalen surfactant und einem von tnf stammenden peptid
HRP20170794T1 (hr) Izvedeni peptidi faktora viii za upotrebu u liječenju hemofilije a