JP2011504169A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011504169A5 JP2011504169A5 JP2010532496A JP2010532496A JP2011504169A5 JP 2011504169 A5 JP2011504169 A5 JP 2011504169A5 JP 2010532496 A JP2010532496 A JP 2010532496A JP 2010532496 A JP2010532496 A JP 2010532496A JP 2011504169 A5 JP2011504169 A5 JP 2011504169A5
- Authority
- JP
- Japan
- Prior art keywords
- carrier
- solid phase
- biological material
- fragments
- phase coating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012634 fragment Substances 0.000 claims 13
- 239000011248 coating agent Substances 0.000 claims 11
- 238000000576 coating method Methods 0.000 claims 11
- 239000012620 biological material Substances 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 239000007790 solid phase Substances 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 241000203069 Archaea Species 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 4
- 210000003527 eukaryotic cell Anatomy 0.000 claims 4
- 229920001223 polyethylene glycol Polymers 0.000 claims 4
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 3
- 239000007864 aqueous solution Substances 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 210000004880 lymph fluid Anatomy 0.000 claims 3
- 230000001954 sterilising effect Effects 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 229910019142 PO4 Inorganic materials 0.000 claims 2
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 230000005250 beta ray Effects 0.000 claims 2
- 230000027455 binding Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 230000005251 gamma ray Effects 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 244000052769 pathogen Species 0.000 claims 2
- 230000001717 pathogenic effect Effects 0.000 claims 2
- 235000021317 phosphate Nutrition 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 229910000077 silane Inorganic materials 0.000 claims 2
- 239000000243 solution Substances 0.000 claims 2
- 235000019698 starch Nutrition 0.000 claims 2
- 238000004659 sterilization and disinfection Methods 0.000 claims 2
- 235000000346 sugar Nutrition 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 235000001014 amino acid Nutrition 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 238000004140 cleaning Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 230000002779 inactivation Effects 0.000 claims 1
- 239000002608 ionic liquid Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims 1
- 239000010452 phosphate Substances 0.000 claims 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 150000005846 sugar alcohols Polymers 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016205673A JP6898722B2 (ja) | 2007-11-07 | 2016-10-20 | 生物学的物質の固定化のための生体適合性三次元マトリクス |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07021661.9A EP2058335B1 (en) | 2007-11-07 | 2007-11-07 | Biocompatible three dimensional matrix for the immobilization of biological substances |
| EP07021661.9 | 2007-11-07 | ||
| PCT/EP2008/009417 WO2009059784A1 (en) | 2007-11-07 | 2008-11-07 | Biocompatible three dimensional matrix for the immobilization of biological substances |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016205673A Division JP6898722B2 (ja) | 2007-11-07 | 2016-10-20 | 生物学的物質の固定化のための生体適合性三次元マトリクス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011504169A JP2011504169A (ja) | 2011-02-03 |
| JP2011504169A5 true JP2011504169A5 (cg-RX-API-DMAC10.html) | 2013-02-07 |
| JP6058877B2 JP6058877B2 (ja) | 2017-01-11 |
Family
ID=39026695
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532496A Expired - Fee Related JP6058877B2 (ja) | 2007-11-07 | 2008-11-07 | 生物学的物質の固定化のための生体適合性三次元マトリクス |
| JP2016205673A Expired - Fee Related JP6898722B2 (ja) | 2007-11-07 | 2016-10-20 | 生物学的物質の固定化のための生体適合性三次元マトリクス |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016205673A Expired - Fee Related JP6898722B2 (ja) | 2007-11-07 | 2016-10-20 | 生物学的物質の固定化のための生体適合性三次元マトリクス |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100291665A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2058335B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP6058877B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN101910202B (cg-RX-API-DMAC10.html) |
| WO (1) | WO2009059784A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2236520A1 (en) * | 2009-03-31 | 2010-10-06 | Leukocare Ag | Stabilizing composition for immobilized biomolecules |
| JP5402721B2 (ja) * | 2010-03-01 | 2014-01-29 | 日立化成株式会社 | 検出装置及び検出方法 |
| EP3744833A1 (en) | 2011-06-28 | 2020-12-02 | Leukocare Ag | Stabilisation method for viruses |
| DE102011051692A1 (de) * | 2011-07-08 | 2013-01-10 | Peter Brehm Chirurgie-Mechanik e.K. | Verfahren zur Sterilisation von funktionalisierten, Nukleotide und/oder Nukleotidderivate enthaltenden, beschichteten Oberflächen |
| EP2902783B1 (en) * | 2012-09-28 | 2017-08-30 | Sekisui Medical Co., Ltd. | Additive for measuring diluted sample in non-dilution-type immunochromatographic method reagent |
| EP2913671A1 (en) * | 2014-02-27 | 2015-09-02 | Leukocare Ag | Novel coated carriers for the specific binding of target molecules |
| SG11201708170VA (en) | 2015-04-13 | 2017-11-29 | Fujifilm Corp | Method for producing short-chain peptide-immobilized carrier, and short-chain peptide-immobilized carrier |
| EP3205261B1 (en) | 2016-02-10 | 2018-03-28 | Nokia Technologies Oy | Intra-oral imaging |
| EP3210539B1 (en) * | 2016-02-24 | 2019-09-11 | Nokia Technologies Oy | Intra-oral x-ray detection |
| CN109232952A (zh) * | 2018-08-07 | 2019-01-18 | 广东元星工业新材料有限公司 | 一种聚氨酯制品表面处理方法 |
| CN109187943B (zh) * | 2018-08-24 | 2021-07-30 | 四川新健康成生物股份有限公司 | 一种抗干扰试剂杯以及试剂杯内抗干扰涂层的制备方法 |
| JP6886668B2 (ja) * | 2019-04-23 | 2021-06-16 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
| CN110895283A (zh) * | 2019-12-10 | 2020-03-20 | 宁波奥丞生物科技有限公司 | 一种高灵敏度的d-二聚体检测试剂盒及其使用方法 |
| GB2631761A (en) * | 2023-07-13 | 2025-01-15 | Mykor Ltd | Insulation |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5426394A (en) * | 1977-07-29 | 1979-02-27 | Unitika Ltd | Method for giving enzymatic activity to solic surface |
| JPS59204601A (ja) * | 1983-05-09 | 1984-11-20 | Unitika Ltd | 生理活性を有する成形体の製造方法 |
| JPS6187700A (ja) * | 1984-10-05 | 1986-05-06 | Shimadzu Corp | ペプチド含有物質固定化物 |
| JPS61124383A (ja) * | 1984-11-16 | 1986-06-12 | Unitika Ltd | 固定化線維素溶解活性酵素の安定化法 |
| CH663728A5 (fr) * | 1985-06-10 | 1988-01-15 | Battelle Memorial Institute | Procede de purification de substances bioactives par adsorption biospecifique. |
| JPS63230088A (ja) * | 1987-03-19 | 1988-09-26 | Ngk Insulators Ltd | 微生物固定化用担体 |
| JPH01181790A (ja) * | 1988-01-18 | 1989-07-19 | Toray Silicone Co Ltd | 生理活性物質の固定化方法 |
| JPH07117519B2 (ja) * | 1988-03-19 | 1995-12-18 | 株式会社堀場製作所 | 酵素固定膜の調製方法 |
| JPH01317389A (ja) * | 1988-06-17 | 1989-12-22 | Tosoh Corp | 生化学反応用担体およびその製造方法 |
| US5077210A (en) * | 1989-01-13 | 1991-12-31 | Eigler Frances S | Immobilization of active agents on substrates with a silane and heterobifunctional crosslinking agent |
| US5283034A (en) * | 1989-06-29 | 1994-02-01 | Applied Immune Sciences, Inc. | Stabilization of sterilized surfaces for research and medical use |
| JPH0419561A (ja) * | 1990-05-14 | 1992-01-23 | Nippon Shokubai Co Ltd | 免疫アッセイ用ブロッキング剤 |
| JPH05219952A (ja) * | 1992-02-14 | 1993-08-31 | Tdk Corp | 酵素固定用担体 |
| JPH0759567A (ja) * | 1993-08-24 | 1995-03-07 | Toyobo Co Ltd | 生理活性物質固定化用担体 |
| US5674292A (en) * | 1995-06-07 | 1997-10-07 | Stryker Corporation | Terminally sterilized osteogenic devices and preparation thereof |
| US6551794B1 (en) * | 1995-11-09 | 2003-04-22 | E. R. Squibb & Sons, Inc. | Stable biotinylated biomolecule composition |
| US5691152A (en) * | 1995-11-09 | 1997-11-25 | E. R. Squibb & Sons, Inc. | Stable avidin composition |
| JP4071283B2 (ja) * | 1996-02-05 | 2008-04-02 | 旭化成クラレメディカル株式会社 | 滅菌保護剤及び滅菌方法 |
| US5760130A (en) * | 1997-05-13 | 1998-06-02 | Molecular Dynamics, Inc. | Aminosilane/carbodiimide coupling of DNA to glass substrate |
| JP4252123B2 (ja) * | 1998-04-23 | 2009-04-08 | ユニチカ株式会社 | 固定化線維素溶解活性酵素の活性安定化法 |
| SG93209A1 (en) * | 1999-07-05 | 2002-12-17 | Inst Of Molecular Agrobiology | A novel immuno-diagnostic test method for veterinary disease |
| AU6093300A (en) * | 1999-07-14 | 2001-02-05 | Genometrix Genomics Incorporated | Arrays comprising non-covalently associated nucleic acid probes and methods for making and using them |
| KR20000071894A (ko) * | 1999-08-19 | 2000-12-05 | 김선영 | 단백질칩 및 이를 이용한 다목적 자동화 진단시스템 |
| US20030012687A1 (en) * | 2000-03-23 | 2003-01-16 | Macphee Martin J. | Methods of sterilizing biological materials |
| WO2002046756A1 (de) * | 2000-11-17 | 2002-06-13 | Zeptosens Ag | Kit und verfahren zur multianalytbestimmung, mit vorkehrungen zur ortsaufgelösten referenzierung einer anregungslichtintensitaet |
| US20030124199A1 (en) * | 2001-08-10 | 2003-07-03 | Karl-Heinz Nietsch | Use of fly larval extracts for wound treatment |
| US6749851B2 (en) * | 2001-08-31 | 2004-06-15 | Clearant, Inc. | Methods for sterilizing preparations of digestive enzymes |
| US7252799B2 (en) * | 2001-08-31 | 2007-08-07 | Clearant, Inc. | Methods for sterilizing preparations containing albumin |
| JP4189644B2 (ja) * | 2003-01-15 | 2008-12-03 | 東洋紡績株式会社 | 生体分子相互作用測定方法 |
| JP2005164348A (ja) * | 2003-12-02 | 2005-06-23 | Toyobo Co Ltd | 生体分子相互作用観察方法 |
| ATE449161T1 (de) * | 2004-03-04 | 2009-12-15 | Leukocare Ag | Leukozytenstimulations-matrix |
| EP1852443A1 (en) * | 2006-05-05 | 2007-11-07 | Leukocare AG | Biocompatible three dimensional matrix for the immobilization of biological substances |
-
2007
- 2007-11-07 EP EP07021661.9A patent/EP2058335B1/en active Active
-
2008
- 2008-11-07 US US12/741,369 patent/US20100291665A1/en not_active Abandoned
- 2008-11-07 JP JP2010532496A patent/JP6058877B2/ja not_active Expired - Fee Related
- 2008-11-07 CN CN200880124134.7A patent/CN101910202B/zh not_active Expired - Fee Related
- 2008-11-07 WO PCT/EP2008/009417 patent/WO2009059784A1/en not_active Ceased
-
2016
- 2016-10-20 JP JP2016205673A patent/JP6898722B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103443117B (zh) | 用于治疗因子在伤口环境中的结合的适体改性的聚合材料 | |
| Chakhalian et al. | Opportunities for biomaterials to address the challenges of COVID‐19 | |
| JP2009536025A5 (cg-RX-API-DMAC10.html) | ||
| ES2673005T3 (es) | Preparación y composición de proteínas inter-alfa inhibidoras a partir de sangre | |
| Bienz et al. | Structural organization of poliovirus RNA replication is mediated by viral proteins of the P2 genomic region | |
| JP6190276B2 (ja) | 自己免疫疾患の治療及び／又は診断におけるアプタマーの使用 | |
| RU2008147885A (ru) | Биосовместимая трехмерная матрица для иммобилизации биологических веществ | |
| KR20240024064A (ko) | 코로나바이러스 및 인플루엔자 조성물 그리고 이의 사용 방법 | |
| Upadhyay et al. | Recent advancement in SARS-CoV-2 diagnosis, treatment, and vaccine formulation: a new paradigm of nanotechnology in strategic combating of COVID-19 pandemic | |
| JP2021072781A (ja) | マーカー系、特にバキュロウイルス発現サブユニット抗原のためのマーカー系 | |
| JPS6098988A (ja) | Ｌｐｆ−ｈａの精製法 | |
| CN1223605C (zh) | 抑制sars冠状病毒的多肽药物及其衍生物和其应用 | |
| CN103205511B (zh) | 一种用于检测鸽细环病毒的引物对及其应用 | |
| WO2024211449A1 (en) | Coronavirus and influenza compositions and methods for using them | |
| JP2010509241A5 (cg-RX-API-DMAC10.html) | ||
| JP4559089B2 (ja) | ウイルス捕捉用スプレー剤及びウイルス捕捉フィルター | |
| WO2021217109A1 (en) | Methods and compositions for enhancing immunogenicity of vaccine | |
| US20230190242A1 (en) | Viral sample collection | |
| JP2020527102A (ja) | 抗体薬物複合体結合後の非結合薬物の除去 | |
| WO2015187885A1 (en) | Method and composition for determining specific antibody responses to species of filovirus | |
| BRPI0412419A (pt) | proteìna de babésia, ácido nucleico, fragmento de cdna, molécula de dna recombinante, veìculo recombinante vivo, célula hospedeira, vacina, método para a preparação de uma vacina, uso de uma proteìna ou um fragmento imunogênico de referida proteìna, e, testes diagnósticos para a detecção de um ácido nucleico associado com, para a detecção de anticorpos contra, e para a detecção de material antigênico de um organismo da famìlia babesiidae | |
| CN117304317A (zh) | Ace2受体特异性结合肽及其应用 | |
| WO2019064463A1 (ja) | バイオアフィニティーを利用したウイルス又は細菌の濃縮方法及び装置 | |
| CA3235306A1 (en) | Devices and methods for treating a viral infection and symptoms thereof | |
| CN107987147A (zh) | 一种mg53多聚体制备方法及其用途 |