JP2011501970A5 - - Google Patents
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- Publication number
- JP2011501970A5 JP2011501970A5 JP2010532268A JP2010532268A JP2011501970A5 JP 2011501970 A5 JP2011501970 A5 JP 2011501970A5 JP 2010532268 A JP2010532268 A JP 2010532268A JP 2010532268 A JP2010532268 A JP 2010532268A JP 2011501970 A5 JP2011501970 A5 JP 2011501970A5
- Authority
- JP
- Japan
- Prior art keywords
- glutaraldehyde
- enzyme catalyst
- catalyst
- produced
- pretreatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003054 catalyst Substances 0.000 claims 13
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 108090000790 Enzymes Proteins 0.000 claims 8
- 102000004190 Enzymes Human genes 0.000 claims 8
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 6
- 230000000694 effects Effects 0.000 claims 4
- 238000000855 fermentation Methods 0.000 claims 3
- 230000004151 fermentation Effects 0.000 claims 3
- 108010093096 Immobilized Enzymes Proteins 0.000 claims 2
- 108010033272 Nitrilase Proteins 0.000 claims 2
- 239000007864 aqueous solution Substances 0.000 claims 2
- 229940113118 carrageenan Drugs 0.000 claims 2
- 235000010418 carrageenan Nutrition 0.000 claims 2
- 229920001525 carrageenan Polymers 0.000 claims 2
- 239000000679 carrageenan Substances 0.000 claims 2
- LTYRAPJYLUPLCI-UHFFFAOYSA-N glycolonitrile Chemical compound OCC#N LTYRAPJYLUPLCI-UHFFFAOYSA-N 0.000 claims 2
- JMANVNJQNLATNU-UHFFFAOYSA-N glycolonitrile Natural products N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 claims 2
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 1
- 229920002873 Polyethylenimine Polymers 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 230000003100 immobilizing effect Effects 0.000 claims 1
- 230000000415 inactivating effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/930,744 | 2007-10-31 | ||
| US11/930,744 US7741088B2 (en) | 2007-10-31 | 2007-10-31 | Immobilized microbial nitrilase for production of glycolic acid |
| PCT/US2008/081952 WO2009059104A1 (en) | 2007-10-31 | 2008-10-31 | Improvement in immobilized microbial nitrilase for production of glycolic acid |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011501970A JP2011501970A (ja) | 2011-01-20 |
| JP2011501970A5 true JP2011501970A5 (enExample) | 2011-12-15 |
| JP5583586B2 JP5583586B2 (ja) | 2014-09-03 |
Family
ID=40229742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010532268A Active JP5583586B2 (ja) | 2007-10-31 | 2008-10-31 | グリコール酸の生産のための固定化微生物ニトリラーゼの改善 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7741088B2 (enExample) |
| EP (1) | EP2215226B9 (enExample) |
| JP (1) | JP5583586B2 (enExample) |
| CN (1) | CN102016018B (enExample) |
| DK (1) | DK2215226T3 (enExample) |
| ES (1) | ES2562791T3 (enExample) |
| PL (1) | PL2215226T3 (enExample) |
| WO (1) | WO2009059104A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2480661A1 (en) * | 2009-09-24 | 2012-08-01 | UCB Pharma, S.A. | Bacterial host strain |
| CA2796158C (en) | 2010-04-14 | 2022-06-14 | Strategic Enzyme Applications, Inc. | Process for producing phosphinothricin employing nitrilases |
| WO2012003336A2 (en) | 2010-06-30 | 2012-01-05 | Codexis, Inc. | Chemically modified carbonic anhydrases useful in carbon capture systems |
| WO2012048865A2 (de) * | 2010-10-12 | 2012-04-19 | C-Lecta Gmbh | Nitrilasen |
| EP3354742A1 (en) | 2017-01-26 | 2018-08-01 | Metabolic Explorer | Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid |
| CN108486088B (zh) | 2018-02-14 | 2021-02-02 | 浙江工业大学 | 腈水解酶突变体及其应用 |
| CN113195727A (zh) * | 2018-10-18 | 2021-07-30 | 巴斯夫欧洲公司 | 用于产生丙烯酸或其盐的方法 |
| CN112063607B (zh) * | 2020-10-09 | 2021-12-07 | 浙江工业大学 | 一种腈水解酶突变体及其在催化合成2-氯烟酸中的应用 |
| CN119570649A (zh) * | 2024-07-12 | 2025-03-07 | 北京衍微科技有限公司 | 含红球菌发酵液的复合催化剂及其用途 |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2175805A (en) | 1937-06-08 | 1939-10-10 | Du Pont | Stabilized organic nitrile and process of making |
| US2890238A (en) | 1957-01-31 | 1959-06-09 | Dow Chemical Co | Preparation of glyconitrile |
| FR2245585B1 (enExample) * | 1973-09-19 | 1976-05-14 | Anvar | |
| DK146942C (da) | 1978-04-19 | 1984-07-30 | Novo Industri As | Fremgangsmaade til fremstilling af et immobiliseret enzymprodukt |
| US4355105A (en) * | 1981-03-30 | 1982-10-19 | Miles Laboratories, Inc. | Glutaraldehyde/polyethylenimine immobilization of whole microbial cells |
| JPS6156086A (ja) | 1984-08-27 | 1986-03-20 | Asahi Chem Ind Co Ltd | α−オキシ酸およびその塩の微生物学的製造法 |
| US5187301A (en) | 1989-10-26 | 1993-02-16 | W. R. Grace & Co.-Conn. | Preparation of iminodiacetonitrile from glycolonitrile |
| DE69131217T2 (de) * | 1990-03-30 | 1999-09-23 | Mitsubishi Rayon Co., Ltd. | Verfahren zur Herstellung von R(-)Mandelsäure und deren Derivaten |
| JP2974737B2 (ja) * | 1990-08-16 | 1999-11-10 | 三菱レイヨン株式会社 | 光学活性乳酸の製造法 |
| DE69126762T2 (de) | 1990-11-14 | 1997-10-23 | Nitto Chemical Industry Co Ltd | Biologisches Verfahren zur Herstellung von Alpha-Hydroxyamid und Alpha-Hydroxysäure |
| JP2676568B2 (ja) * | 1991-06-26 | 1997-11-17 | 日東化学工業株式会社 | Ｒ（−）−マンデル酸およびその誘導体の製造法 |
| US5846762A (en) | 1992-08-26 | 1998-12-08 | Lockheed Martin Energy Research Systems, Inc. | Structurally stable gel bead containing entrapped enzyme and method for manufacture thereof |
| JP3218133B2 (ja) | 1993-02-03 | 2001-10-15 | 三菱レイヨン株式会社 | フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法 |
| JP2720140B2 (ja) | 1993-02-03 | 1998-02-25 | 日東化学工業株式会社 | フェニル基を有する光学活性α−ヒドロキシカルボン酸の製造法 |
| JP3354688B2 (ja) | 1994-01-28 | 2002-12-09 | 三菱レイヨン株式会社 | 微生物によるα−ヒドロキシ酸またはα−ヒドロキシアミドの製造法 |
| US5605793A (en) * | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US5837458A (en) * | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| JP3154646B2 (ja) | 1995-07-19 | 2001-04-09 | 三菱レイヨン株式会社 | グリコール酸の微生物学的製造法 |
| EP0773297B2 (en) * | 1995-11-10 | 2008-04-23 | Mitsubishi Rayon Co., Ltd. | Process for producing alpha-hydroxy acid or alpha-hydroxyamide by microorganism |
| GB9525372D0 (en) | 1995-12-12 | 1996-02-14 | Allied Colloids Ltd | Enzymes, their preparation and their use in the production of ammonium acrylate |
| US5858736A (en) * | 1996-05-17 | 1999-01-12 | E. I. Du Pont De Nemours And Company | Preparation of lactams from aliphatic α,ω-dinitriles |
| US6037155A (en) | 1997-02-27 | 2000-03-14 | Nippon Soda Co., Ltd. | Process for preparing α-hydroxy acids using microorganism and novel microorganism |
| US6291708B1 (en) * | 1999-04-28 | 2001-09-18 | A.E. Staley Manufacturing Co. | Process for production of organic acids and esters thereof |
| US6251646B1 (en) * | 1999-07-12 | 2001-06-26 | E. I. Du Pont De Nemours And Company | Method for stabilizing nitrilase activity and preserving microbial cells |
| US6551804B2 (en) | 1999-07-12 | 2003-04-22 | E. I. Du Pont De Nemours And Company | Process for preparing 4-cyanopentanoic acid |
| KR100501864B1 (ko) * | 1999-11-12 | 2005-07-20 | 미츠비시 레이온 가부시키가이샤 | 사멸화 균체 |
| ATE495244T1 (de) | 2000-03-31 | 2011-01-15 | Du Pont | Isolierung und expression eines nitrilase-gens von acidovorax facilis 72w |
| US6416980B1 (en) | 2001-02-23 | 2002-07-09 | E. I. Du Pont De Nemours & Company | Method for producing glycolic acid from glycolonitrile using nitrilase |
| CN1279013C (zh) * | 2001-05-07 | 2006-10-11 | 嘉吉有限公司 | 羧酸及其衍生物的制备方法 |
| TW200407300A (en) * | 2002-07-12 | 2004-05-16 | Nippon Catalytic Chem Ind | Process for producing diol derivative |
| KR100869623B1 (ko) | 2004-04-27 | 2008-11-21 | 미쓰이 가가쿠 가부시키가이샤 | 하이드록시 카복실산류의 생산 방법 |
| US7148051B2 (en) | 2004-08-16 | 2006-12-12 | E. I. Du Pont De Nemours And Company | Production of 3-hydroxycarboxylic acid using nitrilase |
| EP1828393B1 (en) | 2004-12-22 | 2012-11-07 | E.I. Du Pont De Nemours And Company | Process for producing glycolic acid from formaldehyde and hydrogen cyanide |
| WO2006071663A1 (en) | 2004-12-22 | 2006-07-06 | E.I. Dupont De Nemours And Company | Process for the synthesis of glycolonitrile |
| CN102796770B (zh) | 2004-12-22 | 2014-06-04 | 纳幕尔杜邦公司 | 乙醇酸的酶促生产 |
| US7198927B2 (en) | 2004-12-22 | 2007-04-03 | E. I. Du Pont De Nemours And Company | Enzymatic production of glycolic acid |
| US7445917B2 (en) | 2004-12-22 | 2008-11-04 | E.I. Du Pont De Nemours And Company | Process for producing glycolic acid from formaldehyde and hydrogen cyanide |
| DE102005015570A1 (de) | 2005-04-05 | 2006-10-12 | Robert Bosch Gmbh | Druckregelventil |
| CN101278047B (zh) | 2005-09-30 | 2012-12-12 | 诺维信公司 | 酶的固定化 |
-
2007
- 2007-10-31 US US11/930,744 patent/US7741088B2/en active Active
-
2008
- 2008-10-31 EP EP08845012.7A patent/EP2215226B9/en active Active
- 2008-10-31 DK DK08845012.7T patent/DK2215226T3/en active
- 2008-10-31 ES ES08845012.7T patent/ES2562791T3/es active Active
- 2008-10-31 JP JP2010532268A patent/JP5583586B2/ja active Active
- 2008-10-31 PL PL08845012T patent/PL2215226T3/pl unknown
- 2008-10-31 CN CN2008801241192A patent/CN102016018B/zh not_active Expired - Fee Related
- 2008-10-31 WO PCT/US2008/081952 patent/WO2009059104A1/en not_active Ceased
-
2010
- 2010-02-02 US US12/698,775 patent/US7867748B2/en active Active
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