JP2011141286A5 - - Google Patents

Download PDF

Info

Publication number
JP2011141286A5
JP2011141286A5 JP2011035075A JP2011035075A JP2011141286A5 JP 2011141286 A5 JP2011141286 A5 JP 2011141286A5 JP 2011035075 A JP2011035075 A JP 2011035075A JP 2011035075 A JP2011035075 A JP 2011035075A JP 2011141286 A5 JP2011141286 A5 JP 2011141286A5
Authority
JP
Japan
Prior art keywords
optical
microfluidic device
alignment mark
lens
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2011035075A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011141286A (ja
JP5078106B2 (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2011141286A publication Critical patent/JP2011141286A/ja
Publication of JP2011141286A5 publication Critical patent/JP2011141286A5/ja
Application granted granted Critical
Publication of JP5078106B2 publication Critical patent/JP5078106B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2011035075A 2005-04-12 2011-02-21 マイクロ流体デバイス用の小型光学検出システム Active JP5078106B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67073605P 2005-04-12 2005-04-12
US60/670,736 2005-04-12

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2008506797A Division JP5069220B2 (ja) 2005-04-12 2006-04-12 マイクロ流体デバイス用の小型光学検出システム

Publications (3)

Publication Number Publication Date
JP2011141286A JP2011141286A (ja) 2011-07-21
JP2011141286A5 true JP2011141286A5 (enExample) 2011-10-27
JP5078106B2 JP5078106B2 (ja) 2012-11-21

Family

ID=37215227

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2008506797A Active JP5069220B2 (ja) 2005-04-12 2006-04-12 マイクロ流体デバイス用の小型光学検出システム
JP2011035075A Active JP5078106B2 (ja) 2005-04-12 2011-02-21 マイクロ流体デバイス用の小型光学検出システム

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2008506797A Active JP5069220B2 (ja) 2005-04-12 2006-04-12 マイクロ流体デバイス用の小型光学検出システム

Country Status (7)

Country Link
US (1) US7518726B2 (enExample)
EP (2) EP2453223B1 (enExample)
JP (2) JP5069220B2 (enExample)
CN (1) CN101663576B (enExample)
AU (1) AU2006240184A1 (enExample)
CA (1) CA2603759A1 (enExample)
WO (1) WO2006115863A2 (enExample)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048734A (en) 1995-09-15 2000-04-11 The Regents Of The University Of Michigan Thermal microvalves in a fluid flow method
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US7323140B2 (en) 2001-03-28 2008-01-29 Handylab, Inc. Moving microdroplets in a microfluidic device
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
JP4996248B2 (ja) 2003-07-31 2012-08-08 ハンディーラブ インコーポレイテッド 粒子含有サンプルの処理
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
ES2692380T3 (es) 2006-03-24 2018-12-03 Handylab, Inc. Método para realizar PCR con un cartucho con varias pistas
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8656949B2 (en) * 2006-08-15 2014-02-25 University Of Maryland College Park Microfluidic devices and methods of fabrication
US8765076B2 (en) 2006-11-14 2014-07-01 Handylab, Inc. Microfluidic valve and method of making same
KR101334183B1 (ko) 2007-06-01 2013-12-02 삼성전자주식회사 미세 반응을 위한 형광 검출 모듈과 이를 구비한 형광 검출시스템
ES2648798T3 (es) 2007-07-13 2018-01-08 Handylab, Inc. Materiales de captura de polinucleótidos y métodos de utilización de los mismos
US20090136385A1 (en) 2007-07-13 2009-05-28 Handylab, Inc. Reagent Tube
USD621060S1 (en) 2008-07-14 2010-08-03 Handylab, Inc. Microfluidic cartridge
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8287820B2 (en) * 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8016260B2 (en) 2007-07-19 2011-09-13 Formulatrix, Inc. Metering assembly and method of dispensing fluid
KR100953474B1 (ko) 2008-06-28 2010-04-16 건국대학교 산학협력단 미세유동칩과 마이크로 ｐｉｖ 시스템을 이용한 전자인쇄용잉크의 레올로지 모델 선정방법
USD618820S1 (en) 2008-07-11 2010-06-29 Handylab, Inc. Reagent holder
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
US8926906B2 (en) * 2008-07-21 2015-01-06 Concordia University Microfluidic device and method for fabricating the microfluidic device
EP3181705A1 (en) 2008-11-12 2017-06-21 Caris Life Sciences Switzerland Holdings GmbH Methods and systems of using exosomes for determining phenotypes
US8100293B2 (en) 2009-01-23 2012-01-24 Formulatrix, Inc. Microfluidic dispensing assembly
US8640555B2 (en) * 2009-02-09 2014-02-04 Bioaccel Performance
CN103237901B (zh) 2010-03-01 2016-08-03 卡里斯生命科学瑞士控股有限责任公司 用于治疗诊断的生物标志物
CA2795776A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Circulating biomarkers for disease
EP2612132A4 (en) * 2010-08-31 2014-03-12 Canon Us Life Sciences Inc HIGH RESOLUTION FUSION DETECTION OPTICAL SYSTEM
US9387476B2 (en) 2010-10-27 2016-07-12 Illumina, Inc. Flow cells for biological or chemical analysis
WO2012072795A2 (en) * 2010-12-03 2012-06-07 ALERE TECHNOLOGIES GmbH Transformation of material into an optically modulating state via laser radiation
CA3082652A1 (en) 2011-04-15 2012-10-18 Becton, Dickinson And Company Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection
CN103959070B (zh) 2011-09-30 2017-05-10 贝克顿·迪金森公司 组合试剂条
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
CN104040238B (zh) 2011-11-04 2017-06-27 汉迪拉布公司 多核苷酸样品制备装置
EP2780705B1 (en) 2011-11-16 2018-09-19 Becton, Dickinson and Company Methods and systems for detecting an analyte in a sample
JP6211534B2 (ja) 2011-12-21 2017-10-11 シャハーフ，キャサリン，エム． 組織表面を整列させる病変を撮像するためのシステム
ES2978107T3 (es) 2012-02-03 2024-09-05 Becton Dickinson Co Archivos externos para distribución de pruebas de diagnóstico molecular y determinación de compatibilidad entre pruebas
US10942184B2 (en) 2012-10-23 2021-03-09 Caris Science, Inc. Aptamers and uses thereof
EP2912182B1 (en) 2012-10-23 2021-12-08 Caris Science, Inc. Aptamers and uses thereof
WO2014100434A1 (en) 2012-12-19 2014-06-26 Caris Science, Inc. Compositions and methods for aptamer screening
AU2014205215B2 (en) 2013-01-11 2019-02-14 Becton, Dickinson And Company Low-cost point-of-care assay device
CN103196878A (zh) * 2013-03-18 2013-07-10 杭州德安奇生物工程有限公司 便携式荧光检测器
CN103196879A (zh) * 2013-03-20 2013-07-10 上海如海光电科技有限公司 一种激光诱导荧光光谱检测装置
US20160319361A1 (en) 2013-08-28 2016-11-03 Caris Life Sciences Switzerland Holdings Gmbh Oligonucleotide probes and uses thereof
WO2015069789A1 (en) 2013-11-06 2015-05-14 Becton, Dickinson And Company Microfluidic devices, and methods of making and using the same
US10018640B2 (en) * 2013-11-13 2018-07-10 Becton, Dickinson And Company Optical imaging system and methods for using the same
TWI498535B (zh) * 2013-12-26 2015-09-01 Chroma Ate Inc An optical detection device with an on-line correction function
CN106605164B (zh) 2014-03-04 2020-04-24 诺瓦达克技术公司 用于宽带成像的中继透镜系统
US10948638B2 (en) 2014-03-04 2021-03-16 Stryker European Operations Limited Spatial and spectral filtering apertures and optical imaging systems including the same
EP3239691B1 (en) 2014-12-26 2021-11-17 Sysmex Corporation Cell imaging device, cell imaging method, and sample cell
WO2016145128A1 (en) 2015-03-09 2016-09-15 Caris Science, Inc. Oligonucleotide probes and uses thereof
US9989773B2 (en) 2015-03-30 2018-06-05 Novadaq Technologies, Inc. Multi-channel wide field imaging system and optical system for use therein
US10590425B2 (en) 2015-06-29 2020-03-17 Caris Science, Inc. Therapeutic oligonucleotides
US10941176B2 (en) 2015-07-28 2021-03-09 Caris Science, Inc. Therapeutic oligonucleotides
CN108431649B (zh) 2015-08-31 2021-08-24 史赛克欧洲运营有限公司 偏振依赖滤波器、使用其的系统以及相关联的工具包和方法
AU2017235661B2 (en) 2016-03-18 2023-06-08 Caris Science, Inc. Oligonucleotide probes and uses thereof
US11293017B2 (en) 2016-05-25 2022-04-05 Caris Science, Inc. Oligonucleotide probes and uses thereof
US20210069706A1 (en) * 2017-12-12 2021-03-11 Trustees Of Boston University Disposable fluidic cartridge for interferometric reflectance imaging sensor
US11561221B2 (en) 2018-05-02 2023-01-24 Trustees Of Boston University Dynamic tracking of captured targets for enhanced digital biosensing
US11344882B2 (en) 2018-07-26 2022-05-31 Boe Technology Group Co., Ltd. Microfluidic apparatus, and method of detecting substance in microfluidic apparatus
IL311084A (en) 2018-11-30 2024-04-01 Caris Mpi Inc New generation molecular characterization
CN109724955B (zh) * 2018-12-21 2021-07-06 南京理工大学 一种基于激发配准的塔姆耦合出射角测算方法与装置
CN109932162B (zh) * 2018-12-21 2020-11-06 南京理工大学 一种基于白光配准的腔模参数检测装置及检测方法
CN113316715B (zh) * 2019-01-31 2024-03-15 快速定量微生物学股份有限公司 一种布置光学装置的盒、组件以及方法
US10656368B1 (en) * 2019-07-24 2020-05-19 Omniome, Inc. Method and system for biological imaging using a wide field objective lens
CN114829626A (zh) 2019-10-10 2022-07-29 1859公司 用于微流体筛选的方法和系统
CN114585958B (zh) * 2019-10-19 2024-05-28 美国赛库莱特生物有限公司 显微镜和用于使流体通道中的荧光标记成像的方法
WO2021112918A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor
CA3167961A1 (en) * 2020-02-15 2021-08-19 Heska Corporation Sample cartridges
WO2021202843A1 (en) * 2020-04-01 2021-10-07 Esbiolab Llc Systems and methods for fluorescence imaging
WO2025160418A1 (en) * 2024-01-24 2025-07-31 Armonica Technologies, Inc. Polymer sequencing apparatus, methods and fabrication and use

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06281859A (ja) * 1993-01-26 1994-10-07 Minolta Camera Co Ltd 原稿読取用レンズ
US5539764A (en) * 1994-08-24 1996-07-23 Jamar Technologies Co. Laser generated X-ray source
JPH0882740A (ja) * 1994-09-12 1996-03-26 Olympus Optical Co Ltd 読取り用レンズ
US6008892A (en) * 1997-05-23 1999-12-28 Molecular Dynamics, Inc. Optical substrate for enhanced detectability of fluorescence
FR2784189B3 (fr) * 1998-10-05 2000-11-03 Commissariat Energie Atomique Biopuce et dispositif de lecture d'une biopuce comportant une pluralite de zones de reconnaissance moleculaire
US6498497B1 (en) * 1998-10-14 2002-12-24 Caliper Technologies Corp. Microfluidic controller and detector system with self-calibration
US6533914B1 (en) * 1999-07-08 2003-03-18 Shaorong Liu Microfabricated injector and capillary array assembly for high-resolution and high throughput separation
US6620625B2 (en) * 2000-01-06 2003-09-16 Caliper Technologies Corp. Ultra high throughput sampling and analysis systems and methods
US6589729B2 (en) * 2000-02-04 2003-07-08 Caliper Technologies Corp. Methods, devices, and systems for monitoring time dependent reactions
WO2001090726A2 (en) * 2000-05-19 2001-11-29 Aclara Biosciences, Inc. Optical alignment in capillary detection using capillary wall scatter
US6970245B2 (en) * 2000-08-02 2005-11-29 Honeywell International Inc. Optical alignment detection system
US7097809B2 (en) * 2000-10-03 2006-08-29 California Institute Of Technology Combinatorial synthesis system
JP2003014760A (ja) * 2001-04-27 2003-01-15 Canon Inc プローブ担体、プローブ固定用担体およびそれらの製造方法
US20020174686A1 (en) * 2001-05-07 2002-11-28 The Regents Of The University Of California Method for producing microchannels having circular cross-sections in glass
US7023007B2 (en) * 2001-07-17 2006-04-04 Caliper Life Sciences, Inc. Methods and systems for alignment of detection optics
WO2003008902A1 (en) * 2001-07-17 2003-01-30 Caliper Technologies Corp. Methods and systems for alignment of detection optics
US7033910B2 (en) * 2001-09-12 2006-04-25 Reveo, Inc. Method of fabricating multi layer MEMS and microfluidic devices
GB0209329D0 (en) * 2002-04-24 2002-06-05 Imp College Innovations Ltd A device
EP1508029A4 (en) * 2002-05-28 2010-04-14 Autogenomics Inc MULTIREAGENZPACKUNG
DE10301775A1 (de) * 2003-01-18 2004-07-29 Hentze-Lissotschenko Patentverwaltungs Gmbh & Co.Kg Erfassungsvorrichtung für die optische Erfassung eines Objektes, Verfahren zum Betrieb einer derartigen Erfassungsvorrichtung sowie Scannvorrichtung und konfokales Mikroskop
US6985224B2 (en) * 2003-03-14 2006-01-10 The United States Of America As Represented By The Secretary Of The Navy Light emitting diode (LED) array for excitation emission matrix (EEM) fluorescence spectroscopy
JP2004325174A (ja) * 2003-04-23 2004-11-18 Olympus Corp 蛍光検出装置
US7695683B2 (en) * 2003-05-20 2010-04-13 Fluidigm Corporation Method and system for microfluidic device and imaging thereof
US7654816B2 (en) * 2004-10-07 2010-02-02 Hewlett-Packard Development Company, L.P. Lithographic mask alignment
WO2006084283A2 (en) * 2005-01-31 2006-08-10 The Board Of Trustees Of The University Of Illinois Methods and devices for characterizing particles in clear and turbid media

Similar Documents

Publication Publication Date Title
JP2011141286A5 (enExample)
JP5069220B2 (ja) マイクロ流体デバイス用の小型光学検出システム
JP2010125521A (ja) レーザ加工装置
JP2013065015A5 (enExample)
ATE455312T1 (de) Laser-scanning-mikroskop
CN107407551A (zh) 用于使显微镜自动聚焦到基片上的方法、系统及装置
ATE554416T1 (de) Kalibriervorrichtung und laser-scanning-mikroskop mit einer derartigen kalibriervorrichtung
CN108593529A (zh) 微粒测量装置及其数据处理方法
JP2012038927A5 (enExample)
JP2008281983A5 (enExample)
CN103604787B (zh) 一种激光扫描位相显微成像方法及系统
EP2524260A4 (en) ULTRA DARK FIELD MICROSCOPE
JP2007248063A5 (enExample)
JP2015152405A5 (enExample)
JP6327525B2 (ja) レーザーダイシング装置
JP2007233241A5 (enExample)
JP4454980B2 (ja) 顕微鏡の撮像光学系およびそれを用いた顕微鏡
CN204405545U (zh) 一种自动调焦微流控芯片检测装置
RU2012135405A (ru) Двухфотонный сканирующий микроскоп с автоматической точной фокусировкой изображения и способ автоматической точной фокусировки изображения
JP2010026241A5 (enExample)
JP2013036991A5 (enExample)
JP2012118311A5 (enExample)
TWI617384B (zh) 聚光點檢測裝置
TW200614193A (en) Optical disc apparatus
KR20120055893A (ko) 레이저를 이용한 패턴형성장치