JP2011050389A5 - - Google Patents
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- JP2011050389A5 JP2011050389A5 JP2010228397A JP2010228397A JP2011050389A5 JP 2011050389 A5 JP2011050389 A5 JP 2011050389A5 JP 2010228397 A JP2010228397 A JP 2010228397A JP 2010228397 A JP2010228397 A JP 2010228397A JP 2011050389 A5 JP2011050389 A5 JP 2011050389A5
- Authority
- JP
- Japan
- Prior art keywords
- mammal
- test sample
- polypeptide
- sample
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000000034 method Methods 0.000 claims 21
- 239000000523 sample Substances 0.000 claims 17
- 241000124008 Mammalia Species 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 10
- 230000014509 gene expression Effects 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 210000003719 b-lymphocyte Anatomy 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 230000028993 immune response Effects 0.000 claims 6
- 230000002757 inflammatory effect Effects 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims 4
- 239000013068 control sample Substances 0.000 claims 4
- 208000026278 immune system disease Diseases 0.000 claims 4
- 230000001404 mediated effect Effects 0.000 claims 4
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 2
- 208000011691 Burkitt lymphomas Diseases 0.000 claims 2
- 208000035186 Hemolytic Autoimmune Anemia Diseases 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 208000007924 IgA Deficiency Diseases 0.000 claims 2
- 206010061598 Immunodeficiency Diseases 0.000 claims 2
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 2
- 206010025323 Lymphomas Diseases 0.000 claims 2
- 206010039915 Selective IgA immunodeficiency Diseases 0.000 claims 2
- 208000028483 Selective IgM deficiency Diseases 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 210000004404 adrenal cortex Anatomy 0.000 claims 2
- 208000026935 allergic disease Diseases 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 201000000448 autoimmune hemolytic anemia Diseases 0.000 claims 2
- 230000007812 deficiency Effects 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 230000009610 hypersensitivity Effects 0.000 claims 2
- 230000007813 immunodeficiency Effects 0.000 claims 2
- 201000007156 immunoglobulin alpha deficiency Diseases 0.000 claims 2
- 230000021633 leukocyte mediated immunity Effects 0.000 claims 2
- 206010028417 myasthenia gravis Diseases 0.000 claims 2
- 201000008383 nephritis Diseases 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 208000029138 selective IgA deficiency disease Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 230000001052 transient effect Effects 0.000 claims 2
- 241000972773 Aulopiformes Species 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 229960000633 dextran sulfate Drugs 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 235000019515 salmon Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 229940048086 sodium pyrophosphate Drugs 0.000 claims 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41139202P | 2002-09-16 | 2002-09-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536566A Division JP2006515165A (ja) | 2002-09-16 | 2003-09-15 | 免疫関連疾患の治療のための新規組成物と方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011086366A Division JP2011172580A (ja) | 2002-09-16 | 2011-04-08 | 免疫関連疾患の治療のための新規組成物と方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011050389A JP2011050389A (ja) | 2011-03-17 |
| JP2011050389A5 true JP2011050389A5 (enExample) | 2011-05-26 |
Family
ID=31994259
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536566A Withdrawn JP2006515165A (ja) | 2002-09-16 | 2003-09-15 | 免疫関連疾患の治療のための新規組成物と方法 |
| JP2010228397A Pending JP2011050389A (ja) | 2002-09-16 | 2010-10-08 | 免疫関連疾患の治療のための新規組成物と方法 |
| JP2011086366A Withdrawn JP2011172580A (ja) | 2002-09-16 | 2011-04-08 | 免疫関連疾患の治療のための新規組成物と方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536566A Withdrawn JP2006515165A (ja) | 2002-09-16 | 2003-09-15 | 免疫関連疾患の治療のための新規組成物と方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011086366A Withdrawn JP2011172580A (ja) | 2002-09-16 | 2011-04-08 | 免疫関連疾患の治療のための新規組成物と方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20070010434A1 (enExample) |
| EP (2) | EP2444409A2 (enExample) |
| JP (3) | JP2006515165A (enExample) |
| AU (2) | AU2003291625B2 (enExample) |
| CA (1) | CA2498274A1 (enExample) |
| WO (1) | WO2004024097A2 (enExample) |
Families Citing this family (37)
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| US20050037946A1 (en) * | 2003-01-13 | 2005-02-17 | Millennium Pharmaceuticals, Inc. | Methods and compositions for treating cardiovascular disease using 1722, 10280, 59917, 85553, 10653, 9235, 21668, 17794, 2210, 6169, 10102, 21061, 17662, 1468, 12282, 6350, 9035, 1820, 23652, 7301, 8925, 8701, 3533, 9462, 9123, 12788, 17729, 65552, 1261, 21476, 33770, 9380, 2569654, 33556, 53656, 44143, 32612, 10671, 261, 44570, 41922, 2552, 2417, 19319, 43969, 8921, 8993, 955, 32345, 966, 1920, 17318, 1510, 14180, 26005, 554, 16408, 42028, 112091, 13886, 13942, 1673, 54946 or 2419 |
| EP1460088A1 (en) | 2003-03-21 | 2004-09-22 | Biotest AG | Humanized anti-CD4 antibody with immunosuppressive properties |
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| US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
| US20050272067A1 (en) * | 2004-03-10 | 2005-12-08 | Macina Roberto A | Compositions, splice variants and methods relating to cancer specific genes and proteins |
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| JP2009055838A (ja) * | 2007-08-31 | 2009-03-19 | Nipro Corp | 融合タンパク質、該融合タンパク質に関連する遺伝子、ベクター、形質転換体及び抗炎症性医薬組成物 |
| JP5604311B2 (ja) | 2008-03-13 | 2014-10-08 | バイオテスト・アクチエンゲゼルシヤフト | 疾患治療剤 |
| KR20100135807A (ko) | 2008-03-13 | 2010-12-27 | 바이오테스트 아게 | 질병 치료제 |
| CA2718184A1 (en) | 2008-03-13 | 2009-10-08 | Biotest Ag | Agent for treating disease |
| CA2728363C (en) | 2008-06-26 | 2019-02-19 | Orphazyme Aps | Use of hsp70 as a regulator of enzymatic activity |
| US11693009B2 (en) | 2009-02-11 | 2023-07-04 | Cedars-Sinai Medical Center | Methods for detecting post-infectious irritable bowel syndrome |
| WO2010141999A1 (en) * | 2009-06-12 | 2010-12-16 | The University Of Queensland | Agents and methods for diagnosing and treating ankylosing spondylitis |
| GB0920944D0 (en) | 2009-11-30 | 2010-01-13 | Biotest Ag | Agents for treating disease |
| PL2646044T3 (pl) | 2010-11-30 | 2020-03-31 | Orphazyme A/S | Sposoby zwiększenia aktywności wewnątrzkomórkowej Hsp70 |
| CA2884413C (en) | 2012-09-17 | 2022-11-01 | Cedars-Sinai Medical Center | Diagnosis and treatment of motility disorders of the gut and bladder, and of fibromyalgia |
| AU2014331841B2 (en) | 2013-10-09 | 2020-03-12 | Cedars-Sinai Medical Center | Diagnosis and treatment of irritable bowel syndrome and inflammatory bowel disease |
| HUE055190T2 (hu) | 2013-10-11 | 2021-12-28 | Oxford Bio Therapeutics Ltd | Konjugált antitestek LY75 elleni rák kezelésére |
| JP6678676B2 (ja) | 2014-09-15 | 2020-04-08 | オーファザイム エー/エス | アリモクロモル製剤 |
| SG11201702395WA (en) | 2014-10-09 | 2017-04-27 | Cedars Sinai Medical Center | Methods and systems for distinguishing irritable bowel syndrome from inflammatory bowel disease and celiac disease |
| WO2016065038A1 (en) * | 2014-10-23 | 2016-04-28 | Five Prime Therapeutics, Inc. | Slamf1 antagonists and uses thereof |
| JP6898303B2 (ja) | 2015-08-07 | 2021-07-07 | エーエルエックス オンコロジー インコーポレイテッド | Sirp−アルファドメインまたはそのバリアントを有する構築物 |
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| BR112018070653A2 (pt) | 2016-04-29 | 2019-02-05 | Orphazyme As | ingrediente farmacêutico ativo, e, composição |
| CN109789180B (zh) * | 2016-09-02 | 2023-09-08 | 伊利诺伊大学理事会 | Kif13b衍生的肽和抑制血管生成的方法 |
| JP2020507755A (ja) | 2017-01-30 | 2020-03-12 | シーダーズ−サイナイ メディカル センター | 強皮症の診断法 |
| ES2963157T3 (es) | 2017-07-26 | 2024-03-25 | Forty Seven Inc | Anticuerpos anti-SIRP-alfa y métodos relacionados |
| US11613564B2 (en) | 2019-05-31 | 2023-03-28 | ALX Oncology Inc. | Methods of treating cancer |
| AU2021380947C1 (en) | 2020-11-19 | 2025-02-20 | Zevra Denmark A/S | Processes for preparing arimoclomol citrate and intermediates thereof |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
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| AU2001274888A1 (en) * | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| AU2001264099A1 (en) * | 2000-06-13 | 2001-12-24 | University College Cardiff Consultants Ltd. | Zinc transporters |
| US6974667B2 (en) * | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
| ES2444710T3 (es) * | 2000-06-22 | 2014-02-26 | Amgen, Inc. | Uso de un anticuerpo específico para un polipéptido similar a IL-17 |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| WO2002068579A2 (en) * | 2001-01-10 | 2002-09-06 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
-
2003
- 2003-09-15 JP JP2004536566A patent/JP2006515165A/ja not_active Withdrawn
- 2003-09-15 WO PCT/US2003/029097 patent/WO2004024097A2/en not_active Ceased
- 2003-09-15 EP EP11189800A patent/EP2444409A2/en not_active Withdrawn
- 2003-09-15 US US10/528,260 patent/US20070010434A1/en not_active Abandoned
- 2003-09-15 AU AU2003291625A patent/AU2003291625B2/en not_active Ceased
- 2003-09-15 EP EP03768511A patent/EP1578364A4/en not_active Withdrawn
- 2003-09-15 CA CA002498274A patent/CA2498274A1/en not_active Abandoned
-
2008
- 2008-12-05 US US12/315,879 patent/US20090155263A1/en not_active Abandoned
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2010
- 2010-01-07 AU AU2010200063A patent/AU2010200063B2/en not_active Ceased
- 2010-10-08 JP JP2010228397A patent/JP2011050389A/ja active Pending
- 2010-11-02 US US12/925,947 patent/US20110110938A1/en not_active Abandoned
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2011
- 2011-04-08 JP JP2011086366A patent/JP2011172580A/ja not_active Withdrawn
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