|
WO2010021720A1
(en)
|
2008-08-19 |
2010-02-25 |
Nektar Therapeutics |
Conjugates of small-interfering nucleic acids
|
|
AR081361A1
(es)
|
2010-04-30 |
2012-08-29 |
Molecular Partners Ag |
Proteinas de union modificadas que inhiben la interaccion de receptor del factor de crecimiento endotelial vascular de glicoproteina a vegf-a
|
|
PL2643349T3
(pl)
|
2010-11-26 |
2020-03-31 |
Molecular Partners Ag |
Zaprojektowane białka z powtórzeniami wiążące się z albuminą surowicy
|
|
JP5826863B2
(ja)
|
2011-02-15 |
2015-12-02 |
イミュノジェン・インコーポレーテッド |
細胞傷害性ベンゾジアゼピン誘導体
|
|
JP6209159B2
(ja)
|
2011-06-21 |
2017-10-04 |
イミュノジェン・インコーポレーテッド |
ペプチドリンカーを有する新規メイタンシノイド誘導体およびその結合体
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
EP3566750A3
(en)
|
2013-02-28 |
2020-04-08 |
ImmunoGen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
JP6423804B2
(ja)
|
2013-02-28 |
2018-11-14 |
イミュノジェン・インコーポレーテッド |
細胞結合剤及び細胞毒性剤を含む複合体
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
CN105209483B
(zh)
|
2013-05-31 |
2021-07-27 |
分子组合公司 |
与肝细胞生长因子结合的设计锚蛋白重复蛋白
|
|
CN105873952A
(zh)
|
2013-10-31 |
2016-08-17 |
弗莱德哈钦森癌症研究中心 |
经修饰的造血干细胞/祖细胞和非t效应细胞及其用途
|
|
NZ759969A
(en)
|
2013-12-20 |
2022-12-23 |
Fred Hutchinson Cancer Center |
Tagged chimeric effector molecules and receptors thereof
|
|
US10665324B2
(en)
|
2014-07-07 |
2020-05-26 |
Yeda Research And Development Co. Ltd. |
Method of computational protein design
|
|
AU2015311987B2
(en)
|
2014-09-03 |
2020-06-04 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
WO2016036804A1
(en)
|
2014-09-03 |
2016-03-10 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP4406604A3
(en)
|
2015-03-05 |
2024-10-23 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
|
KR102427117B1
(ko)
|
2015-04-02 |
2022-07-29 |
몰리큘라 파트너스 아게 |
혈청 알부민에 대한 결합 특이성을 갖는 설계된 안키린 반복 도메인
|
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
EP3288569A4
(en)
|
2015-04-29 |
2018-12-19 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
WO2017106728A2
(en)
*
|
2015-12-16 |
2017-06-22 |
University Of Washington |
Repeat protein architectures
|
|
EP4711465A2
(en)
|
2016-04-14 |
2026-03-18 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
CN109790206A
(zh)
|
2016-09-22 |
2019-05-21 |
分子组合公司 |
重组结合蛋白及其用途
|
|
MX2019009552A
(es)
|
2017-02-17 |
2019-10-02 |
Hutchinson Fred Cancer Res |
Terapias de combinacion para el tratamiento de canceres relacionados con el antigeno de maduracion de celulas b (bcma) y trastornos autoinmunitarios.
|
|
TWI781145B
(zh)
|
2017-02-28 |
2022-10-21 |
美商伊繆諾金公司 |
具有自分解肽連接子之類美登素衍生物及其結合物
|
|
WO2018165046A1
(en)
|
2017-03-07 |
2018-09-13 |
Igc Bio, Inc. |
A computational pipeline for antibody modeling and design
|
|
CN119409836A
(zh)
|
2017-03-17 |
2025-02-11 |
弗雷德哈钦森癌症中心 |
免疫调节融合蛋白及其用途
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
US11793885B2
(en)
|
2017-12-28 |
2023-10-24 |
Immunogen, Inc. |
Substituted benzo[5,6][1,4]diazepino[1,2-a]indoles for the treatment of proliferative disorders
|
|
WO2020056170A1
(en)
|
2018-09-12 |
2020-03-19 |
Fred Hutchinson Cancer Research Center |
Reducing cd33 expression to selectively protect therapeutic cells
|
|
KR20220022112A
(ko)
|
2019-03-21 |
2022-02-24 |
이뮤노젠 아이엔씨 |
세포-결합 제제-약물 콘쥬게이트를 준비하는 방법
|
|
CN113661172A
(zh)
|
2019-03-29 |
2021-11-16 |
伊缪诺金公司 |
用于抑制异常细胞生长或治疗增生性疾病的细胞毒性双苯并二氮杂䓬衍生物及其与细胞结合剂的缀合物
|
|
SG11202110922QA
(en)
|
2019-04-26 |
2021-10-28 |
Immunogen Inc |
Camptothecin derivatives
|
|
CA3138805A1
(en)
|
2019-06-04 |
2020-12-10 |
Johannes Schilling |
Designed ankyrin repeat domain with improved stability
|
|
CN114222757A
(zh)
|
2019-06-04 |
2022-03-22 |
分子伴侣公司 |
重组4-1bb结合蛋白及其用途
|
|
JP7611173B2
(ja)
|
2019-06-04 |
2025-01-09 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
組換えfap結合タンパク質及びそれらの使用
|
|
SG11202111943UA
(en)
|
2019-07-02 |
2021-11-29 |
Hutchinson Fred Cancer Res |
Recombinant ad35 vectors and related gene therapy improvements
|
|
WO2021116470A2
(en)
|
2019-12-11 |
2021-06-17 |
Molecular Partners Ag |
Recombinant peptide-mhc complex binding proteins and their generation and use
|
|
IL293698A
(en)
|
2019-12-11 |
2022-08-01 |
Molecular Partners Ag |
Recombinant peptide-mhc complex binding proteins, their production and use
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
JP2023525518A
(ja)
|
2020-05-06 |
2023-06-16 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
新規アンキリンリピート結合タンパク質とその用途
|
|
US20240279309A1
(en)
|
2020-05-14 |
2024-08-22 |
Molecular Partners Ag |
Recombinant cd40 binding proteins and their use
|
|
US20240279290A1
(en)
|
2020-05-14 |
2024-08-22 |
Molecular Partners Ag |
Multispecific proteins
|
|
AU2021403658A1
(en)
|
2020-12-16 |
2023-06-29 |
Molecular Partners Ag |
Recombinant cd3 binding proteins and their use
|
|
AU2021403833A1
(en)
|
2020-12-16 |
2023-07-27 |
Molecular Partners Ag |
Novel slow-release prodrugs
|
|
BR112023018293A2
(pt)
|
2021-03-09 |
2023-10-31 |
Molecular Partners Ag |
Acopladores de célula t multiespecíficos à base de darpin
|
|
US20240317852A1
(en)
|
2021-03-09 |
2024-09-26 |
Molecular Partners Ag |
Novel darpin based cd33 engagers
|
|
CA3211368A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
EP4305063A1
(en)
|
2021-03-09 |
2024-01-17 |
Molecular Partners AG |
Protease cleavable prodrugs
|
|
WO2023110983A1
(en)
|
2021-12-14 |
2023-06-22 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity and their use
|
|
US20250368704A1
(en)
*
|
2022-01-07 |
2025-12-04 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2024028278A1
(en)
|
2022-08-01 |
2024-02-08 |
Molecular Partners Ag |
Charge modified designed repeat domains and their use
|
|
EP4673159A1
(en)
|
2023-02-27 |
2026-01-07 |
Molecular Partners AG |
Darpins for use in reducing renal accumulation of drugs
|
|
EP4724460A1
(en)
|
2023-06-06 |
2026-04-15 |
Molecular Partners AG |
Recombinant cd16a binding proteins and their use
|
|
EP4724486A1
(en)
|
2023-06-06 |
2026-04-15 |
Molecular Partners AG |
Recombinant cd2 binding proteins and their use
|
|
WO2024251695A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd47 binding proteins and their use
|
|
WO2025068607A1
(en)
*
|
2023-09-29 |
2025-04-03 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025146487A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Multispecific binding proteins
|
|
WO2025146490A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
WO2025146491A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
WO2025163144A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
WO2025163083A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recobminant dll3 binding proteins and their use
|
|
WO2025181039A1
(en)
|
2024-03-01 |
2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
WO2025245169A1
(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|