|
US9433684B2
(en)
|
2008-08-19 |
2016-09-06 |
Nektar Therapeutics |
Conjugates of small-interfering nucleic acids
|
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質
|
|
DK2643349T3
(da)
|
2010-11-26 |
2019-11-25 |
Molecular Partners Ag |
Designede repeat-proteiner, der binder til serumalbumin
|
|
JP6049642B2
(ja)
|
2011-02-15 |
2016-12-21 |
イミュノジェン・インコーポレーテッド |
複合体の調製方法
|
|
CN103648532A
(zh)
|
2011-06-21 |
2014-03-19 |
伊缪诺金公司 |
具有肽连接子的新型美登木素生物碱衍生物及其偶联物
|
|
HK1211208A1
(zh)
|
2012-08-22 |
2016-05-20 |
Immunogen, Inc. |
細胞毒性苯並二氮呯衍生物
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
WO2014134486A2
(en)
|
2013-02-28 |
2014-09-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
JP6494533B2
(ja)
|
2013-02-28 |
2019-04-03 |
イミュノジェン・インコーポレーテッド |
細胞結合剤及び細胞毒性剤としてのマイタンシノイドを含む複合体
|
|
US11453708B2
(en)
|
2013-05-31 |
2022-09-27 |
Molecular Partners Ag |
Designed ankyrin repeat proteins binding to hepatocyte growth factor
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
MX389160B
(es)
|
2013-10-31 |
2025-03-20 |
Hutchinson Fred Cancer Res |
Células no t efectoras y madre/progenitoras hematopoyéticas modificadas y usos de estas.
|
|
CN113354744A
(zh)
|
2013-12-20 |
2021-09-07 |
弗雷德哈钦森癌症研究中心 |
带标签的嵌合效应分子及其受体
|
|
EP3167395B1
(en)
|
2014-07-07 |
2020-09-02 |
Yeda Research and Development Co., Ltd. |
Method of computational protein design
|
|
ES2815353T3
(es)
|
2014-09-03 |
2021-03-29 |
Immunogen Inc |
Derivados de benzodiazepina citotóxicos
|
|
EP3189057A1
(en)
|
2014-09-03 |
2017-07-12 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
CA2978186A1
(en)
|
2015-03-05 |
2016-09-09 |
Fred Hutchinson Cancer Research Center |
Immunomodulatory fusion proteins and uses thereof
|
|
AU2016240220B2
(en)
|
2015-04-02 |
2019-11-21 |
Molecular Partners Ag |
Designed ankyrin repeat domains with binding specificity for serum albumin
|
|
WO2016176651A2
(en)
|
2015-04-29 |
2016-11-03 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
EP3288570A4
(en)
|
2015-04-29 |
2018-11-21 |
Fred Hutchinson Cancer Research Center |
Modified stem cells and uses thereof
|
|
WO2017106728A2
(en)
*
|
2015-12-16 |
2017-06-22 |
University Of Washington |
Repeat protein architectures
|
|
AU2017250295B2
(en)
|
2016-04-14 |
2022-08-25 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
US10717772B2
(en)
|
2016-09-22 |
2020-07-21 |
Molecular Partners Ag |
Recombinant binding proteins targeting HER2 and serum albumin, and their uses
|
|
IL268349B2
(en)
|
2017-02-17 |
2024-08-01 |
Hutchinson Fred Cancer Res |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
KR20250171447A
(ko)
|
2017-02-28 |
2025-12-08 |
이뮤노젠 아이엔씨 |
자기희생적 펩티드 링커 및 이들의 접합체를 갖는 메이탄시노이드 유도체
|
|
WO2018165046A1
(en)
|
2017-03-07 |
2018-09-13 |
Igc Bio, Inc. |
A computational pipeline for antibody modeling and design
|
|
AU2018236461B2
(en)
|
2017-03-17 |
2025-03-27 |
Fred Hutchinson Cancer Center |
Immunomodulatory fusion proteins and uses thereof
|
|
WO2018195243A1
(en)
|
2017-04-20 |
2018-10-25 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and conjugates thereof
|
|
TW202413360A
(zh)
|
2017-12-28 |
2024-04-01 |
美商伊繆諾金公司 |
苯二氮平衍生物
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
US11833214B2
(en)
|
2019-03-21 |
2023-12-05 |
Immunogen, Inc. |
Methods of preparing cell-binding agent-drug conjugates
|
|
EP3947395A1
(en)
|
2019-03-29 |
2022-02-09 |
ImmunoGen, Inc. |
Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases
|
|
JP7561141B2
(ja)
|
2019-04-26 |
2024-10-03 |
イミュノジェン・インコーポレーテッド |
カンプトテシン誘導体
|
|
SG11202112925PA
(en)
|
2019-06-04 |
2021-12-30 |
Molecular Partners Ag |
Recombinant fap binding proteins and their use
|
|
US12441772B2
(en)
|
2019-06-04 |
2025-10-14 |
Molecular Partners Ag |
Designed ankyrin repeat domain with improved stability
|
|
EP3980452A1
(en)
|
2019-06-04 |
2022-04-13 |
Molecular Partners AG |
Recombinant 4-1bb binding proteins and their use
|
|
JP2022539248A
(ja)
|
2019-07-02 |
2022-09-07 |
フレッド ハッチンソン キャンサー リサーチ センター |
組換えａｄ３５ベクター及び関連遺伝子治療改善
|
|
KR20220113492A
(ko)
|
2019-12-11 |
2022-08-12 |
몰리큘라 파트너스 아게 |
변경된 표면 잔기를 갖는 설계된 안키린 반복 도메인
|
|
CA3161319A1
(en)
|
2019-12-11 |
2021-06-17 |
Victor LEVITSKY |
Recombinant peptide-mhc complex binding proteins and their generation and use
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
KR20230006558A
(ko)
|
2020-05-06 |
2023-01-10 |
몰리큘라 파트너스 아게 |
신규한 안키린 반복 결합 단백질 및 그의 용도
|
|
US20240279309A1
(en)
|
2020-05-14 |
2024-08-22 |
Molecular Partners Ag |
Recombinant cd40 binding proteins and their use
|
|
IL298168A
(en)
|
2020-05-14 |
2023-01-01 |
Molecular Partners Ag |
Multispecific proteins
|
|
CA3202358A1
(en)
|
2020-12-16 |
2022-06-23 |
Andreas BOSSHART |
Novel slow-release prodrugs
|
|
US20240052033A1
(en)
|
2020-12-16 |
2024-02-15 |
Molecular Partners Ag |
Recombinant cd3 binding proteins and their use
|
|
WO2022190010A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based cd33 engagers
|
|
AU2022233791A1
(en)
|
2021-03-09 |
2023-09-28 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
JP2024509890A
(ja)
|
2021-03-09 |
2024-03-05 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
プロテアーゼ切断可能なプロドラッグ
|
|
IL305677A
(en)
|
2021-03-09 |
2023-11-01 |
Molecular Partners Ag |
Novel darpin based multi-specific t-cell engagers
|
|
IL313411A
(en)
|
2021-12-14 |
2024-08-01 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity and their use
|
|
WO2023131707A1
(en)
*
|
2022-01-07 |
2023-07-13 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
JP2025527242A
(ja)
|
2022-08-01 |
2025-08-20 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
電荷改変され設計された反復ドメイン及びそれらの使用
|
|
EP4673159A1
(en)
|
2023-02-27 |
2026-01-07 |
Molecular Partners AG |
Darpins for use in reducing renal accumulation of drugs
|
|
EP4724473A1
(en)
|
2023-06-06 |
2026-04-15 |
Molecular Partners AG |
Recombinant cd47 binding proteins and their use
|
|
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(en)
|
2023-06-06 |
2026-04-15 |
Molecular Partners AG |
Recombinant cd2 binding proteins and their use
|
|
WO2024251628A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd16a binding proteins and their use
|
|
WO2025068607A1
(en)
*
|
2023-09-29 |
2025-04-03 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025146487A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Multispecific binding proteins
|
|
WO2025146491A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
WO2025146490A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
WO2025163144A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
WO2025163082A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Dll3-specific binding constructs and their use in radiotherapy
|
|
WO2025181039A1
(en)
|
2024-03-01 |
2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
WO2025245169A1
(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|