JP2017530099A5 - - Google Patents
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- JP2017530099A5 JP2017530099A5 JP2017510495A JP2017510495A JP2017530099A5 JP 2017530099 A5 JP2017530099 A5 JP 2017530099A5 JP 2017510495 A JP2017510495 A JP 2017510495A JP 2017510495 A JP2017510495 A JP 2017510495A JP 2017530099 A5 JP2017530099 A5 JP 2017530099A5
- Authority
- JP
- Japan
- Prior art keywords
- binding domain
- fzd
- signaling agonist
- signaling
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462049949P | 2014-09-12 | 2014-09-12 | |
| US62/049,949 | 2014-09-12 | ||
| US201562206150P | 2015-08-17 | 2015-08-17 | |
| US62/206,150 | 2015-08-17 | ||
| PCT/US2015/049829 WO2016040895A1 (en) | 2014-09-12 | 2015-09-11 | Wnt signaling agonist molecules |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138446A Division JP2020186267A (ja) | 2014-09-12 | 2020-08-19 | Ｗｎｔシグナリングアゴニスト分子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530099A JP2017530099A (ja) | 2017-10-12 |
| JP2017530099A5 true JP2017530099A5 (https=) | 2018-09-13 |
| JP6796059B2 JP6796059B2 (ja) | 2020-12-02 |
Family
ID=55459641
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017510495A Active JP6796059B2 (ja) | 2014-09-12 | 2015-09-11 | Ｗｎｔシグナリングアゴニスト分子 |
| JP2020138446A Withdrawn JP2020186267A (ja) | 2014-09-12 | 2020-08-19 | Ｗｎｔシグナリングアゴニスト分子 |
| JP2023080152A Pending JP2023091081A (ja) | 2014-09-12 | 2023-05-15 | Ｗｎｔシグナリングアゴニスト分子 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020138446A Withdrawn JP2020186267A (ja) | 2014-09-12 | 2020-08-19 | Ｗｎｔシグナリングアゴニスト分子 |
| JP2023080152A Pending JP2023091081A (ja) | 2014-09-12 | 2023-05-15 | Ｗｎｔシグナリングアゴニスト分子 |
Country Status (5)
| Country | Link |
|---|---|
| US (4) | US11142577B2 (https=) |
| EP (2) | EP3191526B1 (https=) |
| JP (3) | JP6796059B2 (https=) |
| AU (2) | AU2015314771B2 (https=) |
| WO (1) | WO2016040895A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11142577B2 (en) | 2014-09-12 | 2021-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | WNT signaling agonist molecules |
| US20170349659A1 (en) * | 2016-06-03 | 2017-12-07 | The Board Of Trustees Of The Leland Stanford Junior University | Wnt signaling agonist molecules |
| JP7617603B2 (ja) | 2017-01-11 | 2025-01-20 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | Ｒ－スポンジン（ｒｓｐｏ）サロゲート分子 |
| JP7305543B2 (ja) | 2017-01-26 | 2023-07-10 | スロゼン オペレーティング， インコーポレイテッド | 組織特異的Ｗｎｔシグナル増強分子およびその使用 |
| KR101966523B1 (ko) * | 2017-05-29 | 2019-04-05 | 차의과학대학교 산학협력단 | 오가노이드 배양을 위한 조성물 및 방법 |
| CN111655729B (zh) * | 2017-12-19 | 2023-10-20 | 瑟罗泽恩奥普瑞汀公司 | 抗卷曲蛋白抗体和使用方法 |
| EP3732201A4 (en) | 2017-12-19 | 2022-04-20 | Surrozen Operating, Inc. | WNT SURROGATES AND THEIR USES |
| CN111699003B (zh) * | 2017-12-19 | 2024-05-03 | 瑟罗泽恩奥普瑞汀公司 | 抗lrp5/6抗体和使用方法 |
| US20210032352A1 (en) | 2018-02-14 | 2021-02-04 | Antera Therapeutics Inc. | Multivalent Binding Molecules Activating WNT Signaling and Uses Thereof |
| JP2021518113A (ja) | 2018-03-16 | 2021-08-02 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 心筋細胞を生成及び増殖させるためのｗｎｔアゴニスト、並びに生理活性脂質を用いた試薬及び方法 |
| CA3104526A1 (en) | 2018-07-05 | 2020-01-09 | Surrozen, Inc. | Multi-specific wnt surrogate molecules and uses thereof |
| JP2021530223A (ja) | 2018-07-09 | 2021-11-11 | スロゼン， インコーポレイテッド | 組織特異性Ｗｎｔシグナル増強分子及びその使用 |
| CA3106625A1 (en) | 2018-07-16 | 2020-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Frizzled specific wnt agonists and antagonists |
| US20220064337A1 (en) * | 2018-12-19 | 2022-03-03 | Surrozen, Inc. | Antigen binding formats for receptor complexes |
| JP7663501B2 (ja) * | 2019-02-11 | 2025-04-16 | スロゼン オペレーティング， インコーポレイテッド | 眼障害におけるｗｎｔシグナル伝達の調節 |
| US20220195053A1 (en) * | 2019-03-11 | 2022-06-23 | Surrozen Operating Inc. | Modulation of wnt signaling in gastrointestinal disorders |
| CN120025448A (zh) * | 2019-06-11 | 2025-05-23 | 安托拉诊疗公司 | 多价fzd和wnt结合分子及其用途 |
| AU2020300618A1 (en) | 2019-07-02 | 2022-01-27 | Surrozen Operating, Inc. | Monospecific anti-frizzled antibodies and methods of use |
| EP3789049A1 (en) | 2019-09-06 | 2021-03-10 | QGel SA | Method for obtaining healthy intestinal organoids |
| TW202233656A (zh) | 2020-11-16 | 2022-09-01 | 美商蘇羅森營運公司 | 肝特異性wnt訊號增強分子及其用途 |
| US20240165165A1 (en) * | 2021-01-26 | 2024-05-23 | The Trustees Of Indiana University | Pharmaceutical compositions and their methods of use |
| JP2024509266A (ja) * | 2021-03-10 | 2024-02-29 | スロゼン オペレーティング， インコーポレイテッド | 胃腸障害におけるｗｎｔシグナル伝達のモジュレーション |
| EP4448009A4 (en) * | 2021-12-17 | 2025-12-10 | Surrozen Operating Inc | WNT SUBSTITUTION AGENTS AND LACRYMAL GLAND REGENERATION METHODS |
| WO2024227103A1 (en) * | 2023-04-27 | 2024-10-31 | Surrozen Operating, Inc. | Molecules modulating wnt signaling pathways and uses thereof |
| AU2024279826A1 (en) * | 2023-05-29 | 2026-01-08 | Surrozen Operating, Inc. | Wnt surrogate agents and methods for lacrimal gland regeneration |
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| US5061620A (en) | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
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| US6005079A (en) | 1992-08-21 | 1999-12-21 | Vrije Universiteit Brussels | Immunoglobulins devoid of light chains |
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| DE102004050620A1 (de) | 2004-10-13 | 2006-04-20 | Eberhard-Karls-Universität Tübingen | Monoklonaler Antikörper gegen Frizzled-Rezeptoren |
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| US11142577B2 (en) | 2014-09-12 | 2021-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | WNT signaling agonist molecules |
| US9777052B2 (en) | 2014-12-02 | 2017-10-03 | The Board Of Regents Of The University Of Oklahoma | R-spondin variants, compositions, and methods of use |
| US20160312207A1 (en) | 2015-04-21 | 2016-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | R-spondin antagonists and methods of treating cancer associated with aberrant activation of wnt signaling |
-
2015
- 2015-09-11 US US15/508,779 patent/US11142577B2/en active Active
- 2015-09-11 EP EP15840226.3A patent/EP3191526B1/en active Active
- 2015-09-11 JP JP2017510495A patent/JP6796059B2/ja active Active
- 2015-09-11 EP EP23157332.0A patent/EP4219564A1/en not_active Withdrawn
- 2015-09-11 AU AU2015314771A patent/AU2015314771B2/en active Active
- 2015-09-11 WO PCT/US2015/049829 patent/WO2016040895A1/en not_active Ceased
-
2020
- 2020-08-19 JP JP2020138446A patent/JP2020186267A/ja not_active Withdrawn
-
2021
- 2021-05-13 AU AU2021203059A patent/AU2021203059A1/en not_active Abandoned
- 2021-09-08 US US17/469,661 patent/US20210403578A1/en not_active Abandoned
-
2023
- 2023-05-15 JP JP2023080152A patent/JP2023091081A/ja active Pending
-
2024
- 2024-04-04 US US18/627,108 patent/US20250011437A1/en not_active Abandoned
-
2025
- 2025-03-03 US US19/069,060 patent/US20250304702A1/en active Pending
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