JP2017507670A5 - - Google Patents

Download PDF

Info

Publication number
JP2017507670A5
JP2017507670A5 JP2016570934A JP2016570934A JP2017507670A5 JP 2017507670 A5 JP2017507670 A5 JP 2017507670A5 JP 2016570934 A JP2016570934 A JP 2016570934A JP 2016570934 A JP2016570934 A JP 2016570934A JP 2017507670 A5 JP2017507670 A5 JP 2017507670A5
Authority
JP
Japan
Prior art keywords
pgf2
composition
pacap
derivatives
sdf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2016570934A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017507670A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2015/017392 external-priority patent/WO2015127474A1/en
Publication of JP2017507670A publication Critical patent/JP2017507670A/ja
Publication of JP2017507670A5 publication Critical patent/JP2017507670A5/ja
Pending legal-status Critical Current

Links

JP2016570934A 2014-02-24 2015-02-24 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物 Pending JP2017507670A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461966496P 2014-02-24 2014-02-24
US61/966,496 2014-02-24
PCT/US2015/017392 WO2015127474A1 (en) 2014-02-24 2015-02-24 Methods and compositions for inducing differentiation of human brown adipocyte progenitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019110252A Division JP2019193639A (ja) 2014-02-24 2019-06-13 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物

Publications (2)

Publication Number Publication Date
JP2017507670A JP2017507670A (ja) 2017-03-23
JP2017507670A5 true JP2017507670A5 (https=) 2018-03-22

Family

ID=53879173

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2016570934A Pending JP2017507670A (ja) 2014-02-24 2015-02-24 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物
JP2019110252A Pending JP2019193639A (ja) 2014-02-24 2019-06-13 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物
JP2020206597A Active JP7256165B2 (ja) 2014-02-24 2020-12-14 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物
JP2023056276A Pending JP2023073455A (ja) 2014-02-24 2023-03-30 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2019110252A Pending JP2019193639A (ja) 2014-02-24 2019-06-13 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物
JP2020206597A Active JP7256165B2 (ja) 2014-02-24 2020-12-14 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物
JP2023056276A Pending JP2023073455A (ja) 2014-02-24 2023-03-30 ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物

Country Status (5)

Country Link
US (2) US20220331403A1 (https=)
EP (2) EP3943092B1 (https=)
JP (4) JP2017507670A (https=)
CN (1) CN106255748B (https=)
WO (1) WO2015127474A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5113752B2 (ja) 2005-08-22 2013-01-09 メリオール・ファーマスーティカルズ・ワン・インコーポレイテッド Lynキナーゼの活性を調節し、関連する疾患を治療するための方法および製剤
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
US20190083574A1 (en) * 2016-03-29 2019-03-21 Ohio State Innovation Foundation Thermogenic compositions and methods
JP6909569B2 (ja) * 2016-09-16 2021-07-28 オリザ油化株式会社 肌質改善剤
CA3049165A1 (en) * 2017-01-06 2018-07-12 Iovance Biotherapeutics, Inc. Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
CN108619490A (zh) * 2017-03-22 2018-10-09 天士力医药集团股份有限公司 一种长效化突变的人源成纤维生长因子的新用途
SG11201909406VA (en) * 2017-04-10 2019-11-28 Melior Pharmaceuticals I Inc Treatment of adipocytes
CN109893655B (zh) * 2017-12-11 2021-07-20 义慧科技(深圳)有限公司 miR-327抑制剂和/或FGF10促进剂在预防和/或治疗糖尿病的药物中的应用
CN109893656B (zh) * 2017-12-11 2021-07-20 义慧科技(深圳)有限公司 miR-327抑制剂和/或FGF10促进剂在预防和/或治疗脂肪代谢症药物中的应用
JP2020143008A (ja) * 2019-03-05 2020-09-10 達也 楠堂 新規褐色脂肪細胞分化誘導剤
CN109820857A (zh) * 2019-03-27 2019-05-31 中国科学院广州生物医药与健康研究院 化合物dk45的新应用
CN110747163B (zh) * 2019-11-13 2021-06-11 暨南大学 一种提高人脂肪间充质干细胞成脂分化的方法及其专用培养基
KR102150821B1 (ko) * 2020-01-22 2020-09-03 주식회사 에이스바이오메드 간 질환 치료용 또는 치료 효과 증진을 위한 콜히친 복합제제
CN115916808A (zh) * 2020-05-11 2023-04-04 燃脂医药股份有限公司 用于诱导褐色脂肪生成的方法和组合物
KR102346790B1 (ko) * 2021-04-29 2022-01-04 주식회사 에이스바이오메드 콜히친과 메트포르민을 유효성분으로 하는 항비만 치료제
CN114225006B (zh) * 2021-12-22 2023-10-13 南京市妇幼保健院 一种棕色脂肪细胞分泌肽在低体温疾病防治中的应用
CN115554285B (zh) * 2022-09-25 2026-03-17 华北理工大学 3-去甲基秋水仙碱在药物中的应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10330285A (ja) * 1997-05-30 1998-12-15 Sumitomo Pharmaceut Co Ltd 血糖降下剤
JPH10330284A (ja) * 1997-05-30 1998-12-15 Sumitomo Pharmaceut Co Ltd 肝細胞保護剤
US20050026832A1 (en) 1997-11-25 2005-02-03 Genentech, Inc. Fibroblast growth factor-19 (FGF-19) nucleic acids and polypeptides and methods of use for the treatment of obesity and related disorders
US6242563B1 (en) * 1998-07-20 2001-06-05 Societe De Conseils De Recherches Et D'applications Scientifiques, Sas Peptide analogues
CA2472956A1 (en) * 2002-02-14 2003-08-21 Bayer Pharmaceuticals Corporation Formulation strategies in stabilizing peptides in organic solvents and in dried states
EP1620464A1 (en) * 2003-04-30 2006-02-01 Waratah Pharmaceuticals, Inc. Combined use of keratinocyte growth factor agonists and gastrin compounds
EP1677735B1 (en) * 2003-10-17 2014-07-23 Joslin Diabetes Center, Inc. Methods and compositions for modulating adipocyte function
WO2006108023A2 (en) 2005-04-04 2006-10-12 Joslin Diabetes Center, Inc. Methods and compositions for modulating necdin function
US20100150885A1 (en) 2005-06-01 2010-06-17 Joslin Diabetes Center, Inc. Methods and compositions for inducing brown adipogenesis
CN102083969A (zh) * 2008-05-06 2011-06-01 乔斯林糖尿病中心股份有限公司 诱导褐色脂肪形成的方法和组合物
JP6078228B2 (ja) * 2008-05-27 2017-02-08 オリバー ディー. ボス, ヒト骨格筋における褐色脂肪細胞前駆体
FR2932818B1 (fr) * 2008-06-23 2015-12-04 Centre Nat Rech Scient Lignee d'adipocytes bruns humains et procede de differenciation a partir d'une lignee de cellules hmads.
WO2010011657A1 (en) * 2008-07-23 2010-01-28 Schering Corporation Bicyclic heterocycle derivatives as histamine h3 receptor antagonists
JP5393119B2 (ja) * 2008-12-05 2014-01-22 日本メナード化粧品株式会社 幹細胞の褐色脂肪細胞への分化誘導方法
EP2412800A1 (en) 2010-07-29 2012-02-01 Koninklijke Nederlandse Akademie van Wetenschappen Liver organoid, uses thereof and culture method for obtaining them
MX2011008562A (es) * 2009-02-12 2011-09-09 Proyecto Biomedicina Cima Sl Uso de la cardiotrofina-1 para el tratamiento de enfermedades metabolicas.
US8916517B2 (en) * 2009-11-02 2014-12-23 The Administrators Of The Tulane Educational Fund Analogs of pituitary adenylate cyclase-activating polypeptide (PACAP) and methods for their use
WO2011126790A1 (en) * 2010-03-29 2011-10-13 Joslin Diabetes Center, Inc. Methods and compositions for inducing brown adipogenesis
WO2012099999A2 (en) * 2011-01-20 2012-07-26 Sanford-Burnham Medical Research Institute Methods and compositions for inducing weight loss
AU2012248333B2 (en) * 2011-04-27 2017-05-18 Id Pharma Co., Ltd. Pluripotent stem cell-derived brown adipocytes, pluripotent stem cell-derived cell aggregate, method for producing same, and cell therapy and medical therapy therefor
WO2012156968A2 (en) * 2011-05-19 2012-11-22 Ariel - University Research And Development Company, Ltd. Use of mesenchymal stem cells for the improvement of affective and cognitive function
CA2867922A1 (en) 2011-11-10 2013-05-16 Energesis Pharmaceuticals, Inc. Brown adipocyte progenitors in human skeletal muscle
EP2825638A4 (en) * 2012-03-12 2015-11-25 Univ Singapore GENERATION OF BROWN FAT FABRIC FROM MESENCYCLES
US10335437B2 (en) * 2012-08-10 2019-07-02 The Trustees Of Columbia University In The City Of New York Injectable brown adipose microtissues for treatment and prevention of obesity and diabetes
US20160053227A1 (en) 2013-03-29 2016-02-25 Uha Mikakuto Co., Ltd. Agent for inducing differentiation of white adipocytes into brown-like adipocytes

Similar Documents

Publication Publication Date Title
JP2017507670A5 (https=)
JP7256165B2 (ja) ヒト褐色脂肪細胞前駆体の分化を誘導するための方法および組成物
Quijada et al. The role of the epicardium during heart development and repair
Dore-Duffy Pericytes: pluripotent cells of the blood brain barrier
Won et al. Cell surface engineering to enhance mesenchymal stem cell migration toward an SDF-1 gradient
KR102066987B1 (ko) 폴리펩티드
KR102302634B1 (ko) 변형된 치료제 및 이의 조성물
KR101694405B1 (ko) 폴리펩티드―중합체 접합체 및 그의 사용 방법
US20210393699A1 (en) Factors and cells that provide for induction of bone, bone marrow, and cartilage
JP7617603B2 (ja) R-スポンジン(rspo)サロゲート分子
RU2019112897A (ru) Комбинаторная терапия с агонистами cnp контролируемого высвобождения
CA2976376A1 (en) Nucleic acid products and methods of administration thereof
Lin et al. Multidomain synthetic peptide B2A2 synergistically enhances BMP‐2 in vitro
JP2008546707A (ja) 創傷治癒
Liu et al. The influence of inflammatory cytokines on the proliferation and osteoblastic differentiation of MSCs
Shao et al. The cardiac repair benefits of inflammation do not persist: evidence from mast cell implantation
US20160361386A1 (en) Methods and Compositions for Inducing Differentiation of Human Brown Adipocyte Progenitors
JP6235639B2 (ja) Eph型マ−カ−の細胞/リガンド標識システム、そのシステムからなる細胞物質ならびにその製造方法および前脈管形成としての用途
N. Dube et al. Thymosin β4 protein therapy for cardiac repair
KR20240135690A (ko) 절두된 및 융합 단백질
US20160024249A1 (en) Temperature-Responsive Polymer Compositions and Methods of Use
Chan et al. Harnessing endogenous intra-and extra-cardiac stem cells for cardiac regeneration–hope or hype?
Silveira Fibroblast growth factor and its role in the chondrogenesis of canine mesenchymal stromal cells in three-dimensional collagen scaffolds
Moukadiri et al. Biosynthesis of vasculotropin and expression of vasculotropin receptors by cultured cells
Wilson et al. CXC chemokine receptor signaling in liver repair and regeneration