AU2015314771B2 - Wnt signaling agonist molecules - Google Patents

Wnt signaling agonist molecules Download PDF

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Publication number
AU2015314771B2
AU2015314771B2 AU2015314771A AU2015314771A AU2015314771B2 AU 2015314771 B2 AU2015314771 B2 AU 2015314771B2 AU 2015314771 A AU2015314771 A AU 2015314771A AU 2015314771 A AU2015314771 A AU 2015314771A AU 2015314771 B2 AU2015314771 B2 AU 2015314771B2
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wnt
cells
wnt signaling
agonist
binding domain
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AU2015314771A1 (en
Inventor
David Baker
Luke DANG
Kenan Christopher GARCIA
Claudia Yvonne JANDA
James Daniel MOODY
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University of Washington
Leland Stanford Junior University
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University of Washington
Leland Stanford Junior University
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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AU2015314771A 2014-09-12 2015-09-11 Wnt signaling agonist molecules Active AU2015314771B2 (en)

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AU2021203059A AU2021203059A1 (en) 2014-09-12 2021-05-13 Wnt signaling agonist molecules

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US201462049949P 2014-09-12 2014-09-12
US62/049,949 2014-09-12
US201562206150P 2015-08-17 2015-08-17
US62/206,150 2015-08-17
PCT/US2015/049829 WO2016040895A1 (en) 2014-09-12 2015-09-11 Wnt signaling agonist molecules

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US (4) US11142577B2 (https=)
EP (2) EP3191526B1 (https=)
JP (3) JP6796059B2 (https=)
AU (2) AU2015314771B2 (https=)
WO (1) WO2016040895A1 (https=)

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AU2015314771B2 (en) 2014-09-12 2021-04-01 The Board Of Trustees Of The Leland Stanford Junior University Wnt signaling agonist molecules
US20170349659A1 (en) * 2016-06-03 2017-12-07 The Board Of Trustees Of The Leland Stanford Junior University Wnt signaling agonist molecules
US11993645B2 (en) 2017-01-11 2024-05-28 The Board Of Trustees Of The Leland Stanford Junior University Compositions comprising R-Spondin (RSPO) surrogate molecules
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EP3823661A4 (en) * 2018-07-16 2022-05-11 The Board of Trustees of the Leland Stanford Junior University SPECIFIC FRIZZLED WNT AGONISTS AND ANTAGONISTS
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JP7377288B2 (ja) * 2019-06-11 2023-11-09 アントレラ セラピューティクス インコーポレイテッド 多価ｆｚｄおよびｗｎｔ結合分子とその使用
CA3144499A1 (en) 2019-07-02 2021-01-07 Surrozen Operating, Inc. Monospecific anti-frizzled antibodies and methods of use
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JP2023549854A (ja) 2020-11-16 2023-11-29 スロゼン オペレーティング， インコーポレイテッド 肝臓特異的Ｗｎｔシグナル増強分子およびその使用
WO2022164786A1 (en) * 2021-01-26 2022-08-04 The Trustees Of Indiana University Pharmaceutical compositions and their methods of use
WO2022192445A1 (en) * 2021-03-10 2022-09-15 Surrozen Operating, Inc. Modulation of wnt signaling in gastrointestinal disorders
AU2022413699A1 (en) * 2021-12-17 2024-07-04 Surrozen Operating, Inc. Wnt-surrogate agents and methods for lacrimal gland regeneration
WO2024227103A1 (en) * 2023-04-27 2024-10-31 Surrozen Operating, Inc. Molecules modulating wnt signaling pathways and uses thereof
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