JP2010536713A5 - - Google Patents
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- Publication number
- JP2010536713A5 JP2010536713A5 JP2010506468A JP2010506468A JP2010536713A5 JP 2010536713 A5 JP2010536713 A5 JP 2010536713A5 JP 2010506468 A JP2010506468 A JP 2010506468A JP 2010506468 A JP2010506468 A JP 2010506468A JP 2010536713 A5 JP2010536713 A5 JP 2010536713A5
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- JP
- Japan
- Prior art keywords
- group
- alkyl group
- alkyl
- alkoxy
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 *c(c(*)c1*)c(*)c2c1N(*)C(*)=C(*)C2=O Chemical compound *c(c(*)c1*)c(*)c2c1N(*)C(*)=C(*)C2=O 0.000 description 6
- OFOLQTJFUBLDJJ-UHFFFAOYSA-N CC(C)(C)OP(OCN(C=C(c(cc1)ccc1OC)C(c1c(cc2)F)=O)c1c2OCC1CC1)(OC(C)(C)C)=O Chemical compound CC(C)(C)OP(OCN(C=C(c(cc1)ccc1OC)C(c1c(cc2)F)=O)c1c2OCC1CC1)(OC(C)(C)C)=O OFOLQTJFUBLDJJ-UHFFFAOYSA-N 0.000 description 1
- XPNAOQJTFQZVCX-UHFFFAOYSA-N CCCOc(c(OC=C1c(cc2)ccc2OC)c2C1=O)cc1c2OCCC1 Chemical compound CCCOc(c(OC=C1c(cc2)ccc2OC)c2C1=O)cc1c2OCCC1 XPNAOQJTFQZVCX-UHFFFAOYSA-N 0.000 description 1
- XXXCNANYDDICBK-UHFFFAOYSA-N CCCOc(ccc(F)c12)c1N(COO)C=C(c(ccc(OC)c1)c1F)C2=O Chemical compound CCCOc(ccc(F)c12)c1N(COO)C=C(c(ccc(OC)c1)c1F)C2=O XXXCNANYDDICBK-UHFFFAOYSA-N 0.000 description 1
- QRAFLVRADMSZBP-UHFFFAOYSA-N CCOc(ccc(F)c12)c1N(COC(O)(OC(C)(C)C)OC(C)(C)C)C=C(c(c(OC)c1)ccc1OC)C2=O Chemical compound CCOc(ccc(F)c12)c1N(COC(O)(OC(C)(C)C)OC(C)(C)C)C=C(c(c(OC)c1)ccc1OC)C2=O QRAFLVRADMSZBP-UHFFFAOYSA-N 0.000 description 1
- MNYBFDITJKTSSJ-UHFFFAOYSA-N CN(C1CCCCC1)c(c(N(COP(O)(O)=O)C=C1c(cc2)ccc2OC)c2C1=O)ccc2F Chemical compound CN(C1CCCCC1)c(c(N(COP(O)(O)=O)C=C1c(cc2)ccc2OC)c2C1=O)ccc2F MNYBFDITJKTSSJ-UHFFFAOYSA-N 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010506468A JP5355551B2 (ja) | 2008-12-05 | 2009-12-04 | キノロン化合物及び医薬組成物 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008310739 | 2008-12-05 | ||
| JP2008310739 | 2008-12-05 | ||
| PCT/JP2009/070719 WO2010064735A1 (en) | 2008-12-05 | 2009-12-04 | Quinolone compound and pharmaceutical composition |
| JP2010506468A JP5355551B2 (ja) | 2008-12-05 | 2009-12-04 | キノロン化合物及び医薬組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013173042A Division JP2014001227A (ja) | 2008-12-05 | 2013-08-23 | キノロン化合物及び医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010536713A JP2010536713A (ja) | 2010-12-02 |
| JP2010536713A5 true JP2010536713A5 (enExample) | 2012-08-09 |
| JP5355551B2 JP5355551B2 (ja) | 2013-11-27 |
Family
ID=41716237
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506468A Expired - Fee Related JP5355551B2 (ja) | 2008-12-05 | 2009-12-04 | キノロン化合物及び医薬組成物 |
| JP2013173042A Pending JP2014001227A (ja) | 2008-12-05 | 2013-08-23 | キノロン化合物及び医薬組成物 |
| JP2015085167A Withdrawn JP2015157836A (ja) | 2008-12-05 | 2015-04-17 | キノロン化合物及び医薬組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013173042A Pending JP2014001227A (ja) | 2008-12-05 | 2013-08-23 | キノロン化合物及び医薬組成物 |
| JP2015085167A Withdrawn JP2015157836A (ja) | 2008-12-05 | 2015-04-17 | キノロン化合物及び医薬組成物 |
Country Status (28)
| Country | Link |
|---|---|
| US (4) | USRE45108E1 (enExample) |
| EP (1) | EP2364298B1 (enExample) |
| JP (3) | JP5355551B2 (enExample) |
| KR (5) | KR101548414B1 (enExample) |
| CN (2) | CN103435544A (enExample) |
| AR (1) | AR074486A1 (enExample) |
| AU (1) | AU2009323287B2 (enExample) |
| BR (1) | BRPI0922286A2 (enExample) |
| CA (1) | CA2745019A1 (enExample) |
| CO (1) | CO6331465A2 (enExample) |
| CY (1) | CY1118229T1 (enExample) |
| DK (1) | DK2364298T3 (enExample) |
| ES (1) | ES2594252T3 (enExample) |
| HR (1) | HRP20161209T1 (enExample) |
| HU (1) | HUE029624T2 (enExample) |
| IL (4) | IL212840A0 (enExample) |
| LT (1) | LT2364298T (enExample) |
| MX (1) | MX2011005871A (enExample) |
| MY (1) | MY164007A (enExample) |
| NZ (1) | NZ592881A (enExample) |
| PL (1) | PL2364298T3 (enExample) |
| PT (1) | PT2364298T (enExample) |
| RU (1) | RU2544530C2 (enExample) |
| SI (1) | SI2364298T1 (enExample) |
| TW (2) | TWI492943B (enExample) |
| UA (1) | UA105649C2 (enExample) |
| WO (1) | WO2010064735A1 (enExample) |
| ZA (1) | ZA201103521B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI366565B (en) * | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
| TWI492943B (zh) * | 2008-12-05 | 2015-07-21 | 大塚製藥股份有限公司 | 喹啉酮化合物及藥學組成物（二） |
| WO2010073078A2 (en) * | 2008-12-22 | 2010-07-01 | Orchid Research Laboratories Ltd. | Heterocyclic compounds as hdac inhibitors |
| JP5769504B2 (ja) * | 2010-06-04 | 2015-08-26 | 大塚製薬株式会社 | 医薬 |
| RU2617512C1 (ru) * | 2015-10-23 | 2017-04-25 | Общество с ограниченной ответственностью "Нормофарм" | Средство с антистрессовой, анксиолитической и антидепрессивной активностью и композиция на его основе |
| AU2017218889A1 (en) * | 2016-02-09 | 2018-08-30 | Pharmakea, Inc. | Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof |
| CN106960913A (zh) * | 2017-03-31 | 2017-07-18 | 武汉华星光电技术有限公司 | 量子点发光二极管显示面板及其制备方法 |
| DK3804716T3 (da) | 2018-05-31 | 2025-03-03 | Hua Medicine Shanghai Ltd | Farmaceutisk kombination, sammensætning og kombinationspræparat omfattende glucokinase-aktivator og sglt-2-inhibitor og fremgangsmåder til fremstilling og anvendelser deraf |
| JP2023012557A (ja) * | 2020-02-10 | 2023-01-26 | 大塚製薬株式会社 | 新規肝性脳症治療剤 |
| WO2023286768A1 (en) * | 2021-07-13 | 2023-01-19 | Otsuka Pharmaceutical Co., Ltd. | Hydrogenated quinoxalines |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3416695A1 (de) | 1984-05-05 | 1985-11-07 | Bayer Ag, 5090 Leverkusen | Amidinohydrazone von tetralin-, chromon-, thiochromon- und tretrahydrochinolin-derivaten, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln |
| DE3579581D1 (de) * | 1984-12-11 | 1990-10-11 | Siemens Ag | Anordnung zum ankoppeln von betaetigungsvorrichtungen an elektronische naeherungsschalter hierfuer. |
| MX9200299A (es) | 1991-02-07 | 1992-12-01 | Roussel Uclaf | Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen. |
| IL100555A (en) * | 1991-02-07 | 2000-08-31 | Hoechst Marion Roussel Inc | N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them |
| CA2209134A1 (en) | 1994-12-30 | 1996-07-11 | Ligand Pharmaceuticals Incorporated | Tricyclic retinoids, methods for their production and use |
| GB9621757D0 (en) | 1996-10-18 | 1996-12-11 | Ciba Geigy Ag | Phenyl-substituted bicyclic heterocyclyl derivatives and their use |
| AU7165798A (en) | 1997-04-28 | 1998-11-24 | Anticancer, Inc. | Use of genistein and related compounds to treat certain sex hormone related conditions |
| IT1296985B1 (it) | 1997-12-19 | 1999-08-03 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| WO2000042026A1 (en) | 1999-01-15 | 2000-07-20 | Novo Nordisk A/S | Non-peptide glp-1 agonists |
| EP1173164A2 (en) | 1999-04-16 | 2002-01-23 | AstraZeneca AB | Estrogen receptor-beta ligands |
| JP2002544197A (ja) | 1999-05-06 | 2002-12-24 | ニューロゲン コーポレイション | 置換４−オキソ−キノリン−３−カルボキサミド：ｇａｂａ脳受容体リガンド |
| FR2797444B1 (fr) | 1999-08-13 | 2003-02-07 | Lafon Labor | Compositions pharmaceutiques comprenant des 4-quinolones |
| AUPQ266199A0 (en) | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
| FR2813791B1 (fr) | 2000-09-14 | 2004-03-12 | Lafon Labor | Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale |
| GB0023918D0 (en) | 2000-09-29 | 2000-11-15 | King S College London | Antiparasitic compounds |
| WO2002030407A1 (en) | 2000-10-13 | 2002-04-18 | Astrazeneca Ab | ESTROGEN RECEPTOR-β LIGANDS |
| JP4256679B2 (ja) | 2001-03-16 | 2009-04-22 | ノボゲン リサーチ ピーティーワイ リミテッド | 再狭窄の治療方法 |
| AUPR846401A0 (en) | 2001-10-25 | 2001-11-15 | Novogen Research Pty Ltd | 6-Hydroxy isoflavones, derivatives and medicaments involving same |
| AU2002950217A0 (en) | 2002-07-16 | 2002-09-12 | Prana Biotechnology Limited | 8- Hydroxy Quinoline Derivatives |
| US20040033480A1 (en) | 2002-08-15 | 2004-02-19 | Wong Norman C.W. | Use of resveratrol to regulate expression of apolipoprotein A1 |
| US20050080024A1 (en) | 2002-08-15 | 2005-04-14 | Joseph Tucker | Nitric oxide donating derivatives for the treatment of cardiovascular disorders |
| GB0222516D0 (en) | 2002-09-27 | 2002-11-06 | Karobio Ab | Novel compounds |
| CN1791408A (zh) | 2003-04-03 | 2006-06-21 | 普拉纳生物技术有限公司 | 神经系统疾病的治疗 |
| US7183413B2 (en) | 2003-04-11 | 2007-02-27 | Taigen Biotechnology | Aminoquinoline compounds |
| US20060025337A1 (en) | 2003-07-01 | 2006-02-02 | President And Fellows Of Harvard College | Sirtuin related therapeutics and diagnostics for neurodegenerative diseases |
| KR20060120101A (ko) | 2003-10-10 | 2006-11-24 | 리스버로직스 코퍼레이션 | Ｅｇｒ-1 인핸서 요소와 관련된 질환의 치료 |
| JP2007525485A (ja) | 2003-11-19 | 2007-09-06 | ノボゲン リサーチ ピーティーワイ リミテッド | 複合的な放射線治療及び化学治療の組成物及び方法 |
| KR100636423B1 (ko) | 2004-04-30 | 2006-10-19 | 한국화학연구원 | 신규한 퀴놀리논 유도체, 이의 제조방법 및 이를유효성분으로 하는 약학적 조성물 |
| US7846915B2 (en) | 2004-10-20 | 2010-12-07 | Resverlogix Corporation | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases |
| EP1886996A1 (en) * | 2006-08-10 | 2008-02-13 | Ferrer Internacional, S.A. | 1H-Quinolin-4-one compounds, with affinity for the GABA receptor, processes, uses and compositions |
| TWI366565B (en) | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
| WO2009053799A1 (en) | 2007-10-24 | 2009-04-30 | Glenmark Pharmaceuticals, S.A. | Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation |
| TWI492943B (zh) * | 2008-12-05 | 2015-07-21 | 大塚製藥股份有限公司 | 喹啉酮化合物及藥學組成物（二） |
| KR20110096143A (ko) * | 2008-12-05 | 2011-08-29 | 오츠카 세이야쿠 가부시키가이샤 | 퀴놀론 화합물을 포함하는 약제 |
-
2009
- 2009-12-02 TW TW103145731A patent/TWI492943B/zh not_active IP Right Cessation
- 2009-12-02 TW TW98141152A patent/TWI472525B/zh not_active IP Right Cessation
- 2009-12-04 HR HRP20161209TT patent/HRP20161209T1/hr unknown
- 2009-12-04 PL PL09804077T patent/PL2364298T3/pl unknown
- 2009-12-04 AR ARP090104715 patent/AR074486A1/es unknown
- 2009-12-04 MY MYPI2011002462A patent/MY164007A/en unknown
- 2009-12-04 PT PT98040777T patent/PT2364298T/pt unknown
- 2009-12-04 LT LTEP09804077.7T patent/LT2364298T/lt unknown
- 2009-12-04 CN CN2013103178088A patent/CN103435544A/zh active Pending
- 2009-12-04 RU RU2011127404/04A patent/RU2544530C2/ru not_active IP Right Cessation
- 2009-12-04 KR KR1020127004414A patent/KR101548414B1/ko not_active Expired - Fee Related
- 2009-12-04 CA CA 2745019 patent/CA2745019A1/en not_active Abandoned
- 2009-12-04 KR KR20157007063A patent/KR20150036836A/ko not_active Ceased
- 2009-12-04 SI SI200931526A patent/SI2364298T1/sl unknown
- 2009-12-04 JP JP2010506468A patent/JP5355551B2/ja not_active Expired - Fee Related
- 2009-12-04 CN CN200980148815.1A patent/CN102239147B/zh not_active Expired - Fee Related
- 2009-12-04 KR KR1020167016913A patent/KR20160078518A/ko not_active Ceased
- 2009-12-04 US US14/038,862 patent/USRE45108E1/en not_active Expired - Fee Related
- 2009-12-04 AU AU2009323287A patent/AU2009323287B2/en not_active Ceased
- 2009-12-04 EP EP09804077.7A patent/EP2364298B1/en not_active Not-in-force
- 2009-12-04 ES ES09804077.7T patent/ES2594252T3/es active Active
- 2009-12-04 HU HUE09804077A patent/HUE029624T2/en unknown
- 2009-12-04 BR BRPI0922286A patent/BRPI0922286A2/pt not_active IP Right Cessation
- 2009-12-04 DK DK09804077.7T patent/DK2364298T3/en active
- 2009-12-04 US US12/668,164 patent/US8304546B2/en not_active Ceased
- 2009-12-04 WO PCT/JP2009/070719 patent/WO2010064735A1/en not_active Ceased
- 2009-12-04 KR KR20107002390A patent/KR101278383B1/ko not_active Expired - Fee Related
- 2009-12-04 MX MX2011005871A patent/MX2011005871A/es active IP Right Grant
- 2009-12-04 UA UAA201108418A patent/UA105649C2/uk unknown
- 2009-12-04 NZ NZ59288109A patent/NZ592881A/xx unknown
- 2009-12-04 KR KR1020127027782A patent/KR101662362B1/ko not_active Expired - Fee Related
-
2011
- 2011-05-12 IL IL212840A patent/IL212840A0/en unknown
- 2011-05-13 ZA ZA2011/03521A patent/ZA201103521B/en unknown
- 2011-07-05 CO CO11083156A patent/CO6331465A2/es not_active Application Discontinuation
-
2012
- 2012-09-14 US US13/616,740 patent/US8592593B2/en not_active Expired - Fee Related
-
2013
- 2013-08-23 JP JP2013173042A patent/JP2014001227A/ja active Pending
- 2013-10-18 US US14/057,599 patent/US9018229B2/en not_active Expired - Fee Related
-
2014
- 2014-05-05 IL IL232458A patent/IL232458A0/en unknown
- 2014-05-05 IL IL232459A patent/IL232459A0/en unknown
- 2014-05-05 IL IL232457A patent/IL232457A0/en unknown
-
2015
- 2015-04-17 JP JP2015085167A patent/JP2015157836A/ja not_active Withdrawn
-
2016
- 2016-10-03 CY CY20161100980T patent/CY1118229T1/el unknown
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