JP2010532173A5 - - Google Patents
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- JP2010532173A5 JP2010532173A5 JP2010515226A JP2010515226A JP2010532173A5 JP 2010532173 A5 JP2010532173 A5 JP 2010532173A5 JP 2010515226 A JP2010515226 A JP 2010515226A JP 2010515226 A JP2010515226 A JP 2010515226A JP 2010532173 A5 JP2010532173 A5 JP 2010532173A5
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- Prior art keywords
- cells
- pluripotent
- cell
- population
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000004027 cell Anatomy 0.000 claims description 122
- 238000000034 method Methods 0.000 claims description 60
- 239000007788 liquid Substances 0.000 claims description 26
- 102000035195 Peptidases Human genes 0.000 claims description 25
- 108091005804 Peptidases Proteins 0.000 claims description 25
- 239000002609 medium Substances 0.000 claims description 25
- 239000001963 growth medium Substances 0.000 claims description 22
- 239000003112 inhibitor Substances 0.000 claims description 20
- 238000000926 separation method Methods 0.000 claims description 19
- 108091000080 Phosphotransferase Proteins 0.000 claims description 14
- 102000020233 phosphotransferase Human genes 0.000 claims description 14
- 229940124158 Protease/peptidase inhibitor Drugs 0.000 claims description 9
- 238000004113 cell culture Methods 0.000 claims description 9
- 239000000137 peptide hydrolase inhibitor Substances 0.000 claims description 9
- 238000004891 communication Methods 0.000 claims description 8
- 238000013019 agitation Methods 0.000 claims description 7
- 230000012010 growth Effects 0.000 claims description 6
- 229940122618 Trypsin inhibitor Drugs 0.000 claims description 5
- 101710162629 Trypsin inhibitor Proteins 0.000 claims description 5
- VVBXXVAFSPEIJQ-CVIPOMFBSA-N [(2r)-3-[[(2r)-1-[[(2s,5r,8r,11r,12s,15s,18s,21s)-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-5-[(4-hydroxyphenyl)methyl]-4,11-dimethyl-2-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]am Chemical compound C([C@@H]1C(=O)N[C@@H](C(=O)O[C@H](C)[C@@H](C(N[C@@H](CCCN=C(N)N)C(=O)N[C@H]2CC[C@H](O)N(C2=O)[C@@H](CC(C)C)C(=O)N1C)=O)NC(=O)[C@H](NC(=O)[C@H](O)COS(O)(=O)=O)CC(C)C)C(C)C)C1=CC=C(O)C=C1 VVBXXVAFSPEIJQ-CVIPOMFBSA-N 0.000 claims description 5
- 230000010261 cell growth Effects 0.000 claims description 5
- 239000002753 trypsin inhibitor Substances 0.000 claims description 5
- 102000004142 Trypsin Human genes 0.000 claims description 4
- 108090000631 Trypsin Proteins 0.000 claims description 4
- 230000004069 differentiation Effects 0.000 claims description 4
- 238000012423 maintenance Methods 0.000 claims description 4
- 230000035755 proliferation Effects 0.000 claims description 4
- 239000012588 trypsin Substances 0.000 claims description 4
- 102000004190 Enzymes Human genes 0.000 claims description 3
- 108090000790 Enzymes Proteins 0.000 claims description 3
- 235000010469 Glycine max Nutrition 0.000 claims description 3
- 244000068988 Glycine max Species 0.000 claims description 3
- 239000004365 Protease Substances 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 210000005260 human cell Anatomy 0.000 claims description 2
- 238000010899 nucleation Methods 0.000 claims description 2
- 210000001778 pluripotent stem cell Anatomy 0.000 claims description 2
- 235000019833 protease Nutrition 0.000 claims description 2
- 235000019419 proteases Nutrition 0.000 claims description 2
- 230000001810 trypsinlike Effects 0.000 claims description 2
- 102000000568 rho-Associated Kinases Human genes 0.000 claims 9
- 108010041788 rho-Associated Kinases Proteins 0.000 claims 9
- ADDJDJQFPKUMAF-SFHVURJKSA-N (4s)-5-amino-5-oxo-4-[[4-(4-phenylthiophen-2-yl)benzoyl]amino]pentanoic acid Chemical compound C1=CC(C(=O)N[C@@H](CCC(O)=O)C(=O)N)=CC=C1C1=CC(C=2C=CC=CC=2)=CS1 ADDJDJQFPKUMAF-SFHVURJKSA-N 0.000 claims 1
- 229940121649 protein inhibitor Drugs 0.000 claims 1
- 239000012268 protein inhibitor Substances 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 239000011435 rock Substances 0.000 description 9
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94701307P | 2007-06-29 | 2007-06-29 | |
| US60/947,013 | 2007-06-29 | ||
| PCT/US2008/068814 WO2009006422A1 (en) | 2007-06-29 | 2008-06-30 | Automated method and apparatus for embryonic stem cell culture |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014063625A Division JP2014110817A (ja) | 2007-06-29 | 2014-03-26 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016125186A Division JP2016168056A (ja) | 2007-06-29 | 2016-06-24 | 胚性幹細胞培養のための自動化された方法および装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010532173A JP2010532173A (ja) | 2010-10-07 |
| JP2010532173A5 true JP2010532173A5 (enExample) | 2012-07-26 |
| JP5991796B2 JP5991796B2 (ja) | 2016-09-14 |
Family
ID=39672032
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010515226A Active JP5991796B2 (ja) | 2007-06-29 | 2008-06-30 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2014063625A Pending JP2014110817A (ja) | 2007-06-29 | 2014-03-26 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016125186A Pending JP2016168056A (ja) | 2007-06-29 | 2016-06-24 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016217785A Pending JP2017023158A (ja) | 2007-06-29 | 2016-11-08 | 胚性幹細胞培養のための自動化された方法および装置 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014063625A Pending JP2014110817A (ja) | 2007-06-29 | 2014-03-26 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016125186A Pending JP2016168056A (ja) | 2007-06-29 | 2016-06-24 | 胚性幹細胞培養のための自動化された方法および装置 |
| JP2016217785A Pending JP2017023158A (ja) | 2007-06-29 | 2016-11-08 | 胚性幹細胞培養のための自動化された方法および装置 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8815585B2 (enExample) |
| EP (2) | EP3293256B1 (enExample) |
| JP (4) | JP5991796B2 (enExample) |
| KR (2) | KR20100059789A (enExample) |
| AU (1) | AU2008272949B2 (enExample) |
| CA (1) | CA2691793A1 (enExample) |
| DK (2) | DK2173863T3 (enExample) |
| WO (1) | WO2009006422A1 (enExample) |
Families Citing this family (81)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1962719A4 (en) | 2005-08-29 | 2011-05-04 | Technion Res And Dev Of Foundation Ltd | MEDIA FOR BREEDING STEM CELLS |
| DK3441459T3 (da) | 2006-08-02 | 2021-06-07 | Technion Res & Dev Foundation | Fremgangsmåder til ekspansion af embryonale stamceller i en suspensionskultur |
| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| CA3114827C (en) | 2007-07-31 | 2023-09-05 | Lifescan, Inc. | Differentiation of human embryonic stem cells to pancreatic endocrine |
| RU2551772C2 (ru) | 2008-02-21 | 2015-05-27 | Сентокор Орто Байотек Инк. | Способы, поверхностно-модифицированные носители и композиции для иммобилизации, культивирования и открепления клеток |
| ES2690554T3 (es) | 2008-03-17 | 2018-11-21 | The Scripps Research Institute | Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas |
| US9458431B2 (en) | 2008-03-17 | 2016-10-04 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| JP2011514169A (ja) | 2008-03-17 | 2011-05-06 | エージェンシー フォー サイエンス，テクノロジー アンド リサーチ | 幹細胞培養のためのマイクロキャリア |
| US8828720B2 (en) | 2008-03-17 | 2014-09-09 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| US8691569B2 (en) | 2008-03-17 | 2014-04-08 | Agency For Science, Technology And Research | Microcarriers for stem cell culture |
| AU2009267137A1 (en) | 2008-06-30 | 2010-01-07 | Centocor Ortho Biotech Inc. | Differentiation of pluripotent stem cells |
| WO2010004989A1 (ja) * | 2008-07-07 | 2010-01-14 | タカラバイオ株式会社 | 多能性幹細胞の製造方法 |
| EP3260534A1 (en) | 2008-11-20 | 2017-12-27 | Janssen Biotech, Inc. | Pluripotent stem cell culture on micro-carriers |
| BRPI0921996A2 (pt) | 2008-11-20 | 2015-08-18 | Centocor Ortho Biotech Inc | Métodos e composições para cultura e ligação de células em substratos planos. |
| ES2645869T3 (es) | 2008-12-17 | 2017-12-11 | The Scripps Research Institute | Generación y mantenimiento de células madre |
| JP6189581B2 (ja) | 2009-02-20 | 2017-08-30 | セルラー ダイナミクス インターナショナル， インコーポレイテッド | 幹細胞の分化のための方法および組成物 |
| WO2010107392A1 (en) * | 2009-03-20 | 2010-09-23 | Agency For Science, Technology And Research | Culture of pluripotent and multipotent cells on microcarriers |
| EP2456862A4 (en) | 2009-07-20 | 2013-02-27 | Janssen Biotech Inc | DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS |
| WO2011043077A1 (ja) * | 2009-10-09 | 2011-04-14 | 川崎重工業株式会社 | 未分化多能性幹細胞の識別方法及び装置並びに自動培養方法及び装置 |
| ES2638464T3 (es) * | 2009-10-16 | 2017-10-20 | The Scripps Research Institute | Inducción de células pluripotentes |
| ES2539487T3 (es) * | 2009-11-04 | 2015-07-01 | Cellular Dynamics International, Inc. | Reprogramación episómica con compuestos químicos |
| EP2499236B1 (en) | 2009-11-12 | 2020-01-01 | Technion Research & Development Foundation Ltd. | Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state |
| JP6263329B2 (ja) * | 2009-11-24 | 2018-01-17 | ザ ユニバーシティ オブ コネチカット | ヒト胚性および人工多能性幹細胞の分化 |
| BR112012017761A2 (pt) | 2009-12-23 | 2015-09-15 | Centocor Ortho Biotech Inc | diferenciação das células-tronco embrionárias humanas |
| US9969981B2 (en) | 2010-03-01 | 2018-05-15 | Janssen Biotech, Inc. | Methods for purifying cells derived from pluripotent stem cells |
| AU2011235212B2 (en) | 2010-03-31 | 2014-07-31 | The Scripps Research Institute | Reprogramming cells |
| CN105154394B (zh) * | 2010-05-05 | 2019-06-18 | 泰尔茂比司特公司 | 重新接种中空纤维生物反应器系统中生长的贴壁细胞的方法 |
| US20130071927A1 (en) * | 2010-05-05 | 2013-03-21 | Sydney Ivf Limited | Media and methods for cell culture |
| EP3399026B1 (en) | 2010-06-14 | 2024-06-26 | The Scripps Research Institute | Reprogramming of cells to a new fate |
| EP2586872B1 (en) | 2010-06-25 | 2017-07-26 | Kawasaki Jukogyo Kabushiki Kaisha | Method and device for identifying multipotent stem cell colony, and method and device for automatic culturing of multipotent stem cells |
| CA2809300A1 (en) | 2010-08-31 | 2012-03-08 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| US10214722B2 (en) | 2010-09-07 | 2019-02-26 | Technion Research & Development Foundation Limited | Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture |
| CN106893692B (zh) | 2010-12-22 | 2021-11-26 | 菲特治疗公司 | 用于单细胞分选与增强ipsc重新编程的细胞培养平台 |
| KR101293300B1 (ko) * | 2011-04-05 | 2013-08-09 | (주)로고스바이오시스템스 | 세포의 분리시기를 판정하는 방법과, 이를 이용한 세포의 계대 배양 방법 및 계대 배양 장치 |
| JP6162604B2 (ja) * | 2011-10-21 | 2017-07-12 | 国立大学法人京都大学 | 層流による多能性維持単一分散細胞培養法 |
| US10428309B2 (en) | 2011-12-01 | 2019-10-01 | New York Stem Cell Foundation, Inc. | Systems and methods for producing stem cells and differentiated cells |
| EP3653698B1 (en) * | 2011-12-01 | 2025-04-02 | New York Stem Cell Foundation, Inc. | Automated system for producing induced pluripotent stem cells or differentiated cells |
| AU2012355698B2 (en) | 2011-12-22 | 2018-11-29 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into single hormonal insulin positive cells |
| CN102604894B (zh) | 2012-02-29 | 2014-07-30 | 中国科学院广州生物医药与健康研究院 | 用于制备神经干细胞的培养基及其用途 |
| RU2018108850A (ru) | 2012-06-08 | 2019-02-26 | Янссен Байотек, Инк. | Дифференцировка эмбриональных стволовых клеток человека в панкреатические эндокринные клетки |
| MX2015008577A (es) | 2012-12-31 | 2015-09-07 | Janssen Biotech Inc | Cultivo de celulas madre embrionarias humanas en la interfase aire-liquido para la diferenciacion en celulas endocrinas pancreaticas. |
| EP4039798A1 (en) | 2012-12-31 | 2022-08-10 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent cells |
| SG10201707811XA (en) | 2012-12-31 | 2017-11-29 | Janssen Biotech Inc | Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| US9790465B2 (en) | 2013-04-30 | 2017-10-17 | Corning Incorporated | Spheroid cell culture well article and methods thereof |
| AU2014287013B2 (en) | 2013-07-12 | 2020-01-23 | President And Fellows Of Harvard College | Systems and methods for cell culture device interconnection and fluidic device interconnection |
| EP3033414A4 (en) * | 2013-08-12 | 2017-03-22 | Invivosciences Inc. | Automated cell culture system and method |
| SG10201807292YA (en) | 2014-03-04 | 2018-09-27 | Fate Therapeutics Inc | Improved reprogramming methods and cell culture platforms |
| KR102162138B1 (ko) | 2014-05-16 | 2020-10-06 | 얀센 바이오테크 인코포레이티드 | 췌장 내분비 세포에서 mafa 발현을 향상시키기 위한 소분자의 용도 |
| EP3183338B1 (en) | 2014-08-19 | 2020-03-04 | FUJIFILM Cellular Dynamics, Inc. | Neural networks formed from cells derived from pluripotent stem cells |
| CN120924475A (zh) | 2014-09-18 | 2025-11-11 | 北卡罗来纳大学 | 哺乳动物肺球体和肺球体细胞及其应用 |
| SG11201703500XA (en) | 2014-10-29 | 2017-05-30 | Corning Inc | Perfusion bioreactor platform |
| JP2017532971A (ja) | 2014-10-29 | 2017-11-09 | コーニング インコーポレイテッド | 細胞培養集合体を生成するためのマイクロウェル設計および製造 |
| CN107109328B (zh) | 2014-10-29 | 2021-02-05 | 康宁股份有限公司 | 细胞培养插入件 |
| SG11201704961VA (en) | 2014-12-19 | 2017-07-28 | Janssen Biotech Inc | Suspension culturing of pluripotent stem cells |
| US9944894B2 (en) | 2015-01-16 | 2018-04-17 | General Electric Company | Pluripotent stem cell expansion and passage using a rocking platform bioreactor |
| WO2016208755A1 (ja) * | 2015-06-25 | 2016-12-29 | 株式会社カネカ | 液体注入方法 |
| WO2017007278A1 (ko) * | 2015-07-09 | 2017-01-12 | 사회복지법인 삼성생명공익재단 | 자동 세포 배양기 및 그 배양기의 동작 방법 |
| CA2996582A1 (en) * | 2015-08-31 | 2017-03-09 | I Peace, Inc. | Pluripotent stem cell manufacturing system and method for producing induced pluripotent stem cells |
| CN108367290B (zh) | 2015-10-01 | 2021-06-04 | 伯克利之光生命科技公司 | 井孔板培养器 |
| AU2016338680B2 (en) | 2015-10-16 | 2022-11-17 | Fate Therapeutics, Inc. | Platform for the induction and maintenance of ground state pluripotency |
| EP3423158B1 (en) | 2016-02-24 | 2023-11-15 | The Rockefeller University | Embryonic cell-based therapeutic candidate screening systems, models for huntington's disease and uses thereof |
| CN108779424A (zh) * | 2016-03-21 | 2018-11-09 | 通用电气公司 | 使用搅拌槽生物反应器的多能干细胞扩增和传代 |
| MA45479A (fr) | 2016-04-14 | 2019-02-20 | Janssen Biotech Inc | Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen |
| JP2018000130A (ja) * | 2016-07-05 | 2018-01-11 | 株式会社Ihi | 細胞培養装置 |
| KR102711870B1 (ko) | 2016-07-19 | 2024-10-02 | 아셀라타 리미티드 | 현탁 내 만능줄기세포를 배양하기 위한 배양 배지 |
| DE102016114043B3 (de) | 2016-07-29 | 2017-08-10 | Technische Universität Dresden | Vorrichtung zur Isolierung von Stammzellen aus fötalen Geweben |
| CN115044471B (zh) | 2016-08-27 | 2025-05-27 | 三维生物科技有限公司 | 生物反应器 |
| CA3043012A1 (en) | 2016-11-10 | 2018-05-17 | Becton, Dickinson And Company | Timeline system for monitoring a culture media protocol |
| WO2018102781A1 (en) * | 2016-12-01 | 2018-06-07 | Berkeley Lights, Inc. | Well-plate incubator |
| CA3053891C (en) * | 2017-02-27 | 2023-05-23 | I Peace, Inc. | Somatic cell production system |
| JP6530876B2 (ja) * | 2017-02-27 | 2019-06-12 | 剛士 田邊 | 細胞処理システム及び細胞処理装置 |
| US11857970B2 (en) | 2017-07-14 | 2024-01-02 | Corning Incorporated | Cell culture vessel |
| WO2019014636A1 (en) | 2017-07-14 | 2019-01-17 | Corning Incorporated | CONTAINER FOR CELL CULTURE |
| EP3652292B1 (en) | 2017-07-14 | 2025-06-18 | Corning Incorporated | Cell culture vessel for 3d culture and methods of culturing 3d cells |
| WO2019014635A1 (en) | 2017-07-14 | 2019-01-17 | Corning Incorporated | 3D CELL CULTURE CONTAINERS FOR MANUAL OR AUTOMATIC EXCHANGE |
| KR102220125B1 (ko) * | 2018-04-26 | 2021-02-25 | (주)세포바이오 | 세포배양 자동화 장치 및 방법 |
| CN111032851B (zh) | 2018-07-13 | 2024-03-29 | 康宁股份有限公司 | 具有包含液体介质传递表面的侧壁的微腔皿 |
| EP3649227A1 (en) | 2018-07-13 | 2020-05-13 | Corning Incorporated | Fluidic devices including microplates with interconnected wells |
| CN111051493B (zh) | 2018-07-13 | 2023-11-03 | 康宁股份有限公司 | 具有稳定器装置的细胞培养容器 |
| US20230035127A1 (en) * | 2021-07-21 | 2023-02-02 | University Of Maryland, College Park | Culture and differentiation of pluripotent stem cells |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352883A (en) * | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4284412A (en) | 1979-07-13 | 1981-08-18 | Ortho Diagnostics, Inc. | Method and apparatus for automated identification and enumeration of specified blood cell subclasses |
| JPS58155087A (ja) * | 1982-03-12 | 1983-09-14 | Olympus Optical Co Ltd | 細胞の自動培養装置 |
| US4498766A (en) | 1982-03-25 | 1985-02-12 | Becton, Dickinson And Company | Light beam focal spot elongation in flow cytometry devices |
| US4661913A (en) | 1984-09-11 | 1987-04-28 | Becton, Dickinson And Company | Apparatus and method for the detection and classification of articles using flow cytometry techniques |
| US4774189A (en) | 1984-12-24 | 1988-09-27 | Flow Cytometry Standards Corp. | Fluorescent calibration microbeads simulating stained cells |
| US4857451A (en) * | 1984-12-24 | 1989-08-15 | Flow Cytometry Standards Corporation | Method of compensating and calibrating a flow cytometer, and microbead standards kit therefor |
| US4767206A (en) | 1984-12-24 | 1988-08-30 | Flow Cytometry Standards Corporation | Calibration method for flow cytometry using fluorescent microbeads and synthesis thereof |
| US4989977A (en) * | 1985-07-29 | 1991-02-05 | Becton, Dickinson And Company | Flow cytometry apparatus with improved light beam adjustment |
| US4714682A (en) | 1985-12-11 | 1987-12-22 | Flow Cytometry Standards Corporation | Fluorescent calibration microbeads simulating stained cells |
| US5160974A (en) * | 1990-06-25 | 1992-11-03 | Flow Science, Inc. | Closed sample cell for use in flow cytometry |
| US5478722A (en) * | 1991-02-17 | 1995-12-26 | The Curators Of The University Of Missouri | Preserved cell preparations for flow cytometry and immunology |
| EP0682697A4 (en) | 1993-01-29 | 1997-07-30 | New Brunswick Scientific Co | METHOD AND APPARATUS FOR CULTURING ANCHOR AND SUSPENSION CELLS. |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US6325114B1 (en) | 2000-02-01 | 2001-12-04 | Incyte Genomics, Inc. | Pipetting station apparatus |
| KR20050006147A (ko) | 2002-04-08 | 2005-01-15 | 밀레늄 바이올로직스 인코포레이티드 | 자동화된 조직 엔지니어링 시스템 |
| DE102004043256B4 (de) * | 2004-09-07 | 2013-09-19 | Rheinische Friedrich-Wilhelms-Universität Bonn | Skalierbarer Prozess zur Kultivierung undifferenzierter Stammzellen in Suspension |
| ES2383813T3 (es) * | 2004-09-08 | 2012-06-26 | Wisconsin Alumni Research Foundation | Método de cultivo y cultivo de células madre embrionarias |
| US20060198827A1 (en) | 2005-02-04 | 2006-09-07 | Shulamit Levenberg | Engineering vascularized muscle tissue |
| US20060199265A1 (en) | 2005-03-02 | 2006-09-07 | Wolf Michael F | Seeding implantable medical devices with cells |
-
2008
- 2008-06-30 KR KR1020107002003A patent/KR20100059789A/ko not_active Ceased
- 2008-06-30 DK DK08781187.3T patent/DK2173863T3/en active
- 2008-06-30 KR KR1020157036767A patent/KR20160005142A/ko not_active Ceased
- 2008-06-30 WO PCT/US2008/068814 patent/WO2009006422A1/en not_active Ceased
- 2008-06-30 DK DK17192886.4T patent/DK3293256T3/da active
- 2008-06-30 JP JP2010515226A patent/JP5991796B2/ja active Active
- 2008-06-30 CA CA2691793A patent/CA2691793A1/en not_active Abandoned
- 2008-06-30 EP EP17192886.4A patent/EP3293256B1/en active Active
- 2008-06-30 EP EP08781187.3A patent/EP2173863B1/en active Active
- 2008-06-30 AU AU2008272949A patent/AU2008272949B2/en active Active
- 2008-06-30 US US12/164,969 patent/US8815585B2/en active Active
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2013
- 2013-03-19 US US13/847,349 patent/US20130316445A1/en not_active Abandoned
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2014
- 2014-03-26 JP JP2014063625A patent/JP2014110817A/ja active Pending
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2016
- 2016-06-24 JP JP2016125186A patent/JP2016168056A/ja active Pending
- 2016-11-08 JP JP2016217785A patent/JP2017023158A/ja active Pending
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