JP2010531846A5 - - Google Patents

Download PDF

Info

Publication number
JP2010531846A5
JP2010531846A5 JP2010513952A JP2010513952A JP2010531846A5 JP 2010531846 A5 JP2010531846 A5 JP 2010531846A5 JP 2010513952 A JP2010513952 A JP 2010513952A JP 2010513952 A JP2010513952 A JP 2010513952A JP 2010531846 A5 JP2010531846 A5 JP 2010531846A5
Authority
JP
Japan
Prior art keywords
antibody
binding fragment
fragment
antagonist
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010513952A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010531846A (ja
JP5554703B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2008/058339 external-priority patent/WO2009000929A2/en
Publication of JP2010531846A publication Critical patent/JP2010531846A/ja
Publication of JP2010531846A5 publication Critical patent/JP2010531846A5/ja
Application granted granted Critical
Publication of JP5554703B2 publication Critical patent/JP5554703B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010513952A 2007-06-28 2008-06-27 自己免疫疾患の治療のための組成物および方法 Active JP5554703B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
IE20070468 2007-06-28
IE2007/0468 2007-06-28
US3837208P 2008-03-20 2008-03-20
US61/038,372 2008-03-20
IE20080209 2008-03-20
IE2008/0209 2008-03-20
PCT/EP2008/058339 WO2009000929A2 (en) 2007-06-28 2008-06-27 Composition and method for treatment of autoimmune disease

Publications (3)

Publication Number Publication Date
JP2010531846A JP2010531846A (ja) 2010-09-30
JP2010531846A5 true JP2010531846A5 (https=) 2011-08-04
JP5554703B2 JP5554703B2 (ja) 2014-07-23

Family

ID=39758798

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010513952A Active JP5554703B2 (ja) 2007-06-28 2008-06-27 自己免疫疾患の治療のための組成物および方法

Country Status (7)

Country Link
US (1) US8580255B2 (https=)
EP (1) EP2170392A2 (https=)
JP (1) JP5554703B2 (https=)
CN (1) CN101808662A (https=)
AU (1) AU2008267151B2 (https=)
CA (1) CA2691784C (https=)
WO (1) WO2009000929A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100278817A1 (en) * 2007-07-05 2010-11-04 Opsona Therapeutics Ltd. Compounds and methods for the treatment of renal disease
US9981018B2 (en) 2010-06-08 2018-05-29 The Cleveland Clinic Foundation Compositions and methods for modulating toll-like receptor 2 activation
WO2011156451A2 (en) * 2010-06-08 2011-12-15 The Cleveland Clinic Foundation Compositions and methods for modulating toll-like receptor 2 activation
WO2012011100A1 (en) * 2010-07-19 2012-01-26 Yeda Research And Development Co. Ltd. Peptides based on the transmembrane domain of a toll-like receptor (tlr) for treatment of tlr-mediated diseases
CN103562387A (zh) 2011-03-03 2014-02-05 夸克医药公司 Toll样受体途径的寡核苷酸调剂
US9796979B2 (en) 2011-03-03 2017-10-24 Quark Pharmaceuticals Inc. Oligonucleotide modulators of the toll-like receptor pathway
EP2970428A4 (en) * 2013-03-15 2016-08-31 Univ Florida COMPOUNDS FOR THE TREATMENT OF NEURODEEGENERATIVE PROTEINOPATHIES
WO2016154586A1 (en) * 2015-03-26 2016-09-29 H. Lee Moffitt Cancer Center And Research Institute, Inc. Toll-like receptor 2 ligands and methods of making and using thereof
CN107847657A (zh) * 2015-06-15 2018-03-27 生命治疗有限公司 用于诱导抗炎反应的组合物和方法
EP3735129B1 (en) 2018-01-02 2025-02-05 Rush University Medical Center Compositions and methods for treating neurological and other disorders
WO2020011869A2 (en) 2018-07-11 2020-01-16 Roche Innovation Center Copenhagen A/S Antisense oligonucleotides targeting tlr2

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9927332D0 (en) 1999-11-18 2000-01-12 Leiv Eiriksson Nyfotek As Novel antibody and uses thereof
US7388080B2 (en) * 2003-08-20 2008-06-17 University Of Massachusetts Selective inhibition of toll-like receptor-2
ATE510853T1 (de) * 2003-09-23 2011-06-15 Univ Muenchen Tech Tlr2-antagonistischer antikörper und dessen verwendung
WO2005039504A2 (en) * 2003-10-24 2005-05-06 Eisai Co., Ltd. Compounds and methods for treating toll-like receptor 2-related diseases and conditions
WO2005079419A2 (en) * 2004-02-17 2005-09-01 The Regents Of The University Of California Methods of treating immunopathological disorders
AU2005325482B2 (en) * 2004-12-10 2011-06-16 Novimmune S.A. Combining therapies targeting multiple toll-like receptors and use thereof
CA2596509A1 (en) 2005-02-14 2006-08-24 Wyeth Interleukin-17f antibodies and other il-17f signaling antagonists and uses therefor
EP2139916A1 (en) 2007-04-26 2010-01-06 Opsona Therapeutics Limited Toll-like receptor binding epitope and compositions for binding thereto

Similar Documents

Publication Publication Date Title
JP2010531846A5 (https=)
Chu et al. Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody
ES2514495T3 (es) Anticuerpos humanizados modificados anti-interleucina-18
HRP20191341T1 (hr) Protutijela koja vežu ljudski cgrp receptor
Shaw et al. Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling
TWI687440B (zh) St2l拮抗劑及使用方法
HRP20231031T1 (hr) Protutijela protiv sars-cov-2
FI3592384T3 (fi) Vasta-aineita, jotka spesifisesti sitoutuvat ihmisen IL-1R7:ään
JP2015535820A5 (https=)
US10618957B2 (en) Antibody molecules which bind CD79
JP2022031635A5 (https=)
HRP20191342T1 (hr) Anti-phf-tau antitijela i njihove upotrebe
JP2012516158A5 (https=)
JP2012501670A5 (https=)
HRP20171080T1 (hr) Protutijela s modificiranim affinitetom za fcrn koja potiču uklanjanje antigena
JP2017522043A5 (https=)
JP2012531922A5 (ja) Toll様受容体2へのヒト化抗体またはその抗原結合部位
CA2992372A1 (en) Antibody molecules which bind cd22
EA201001467A1 (ru) Моноклональное антитело и способ его использования
JP2018537400A5 (https=)
JP2015501291A5 (https=)
JP2012524071A5 (https=)
EP3169705A2 (en) Molecules with specificity for cd79 and cd22
CN103145840A (zh) Il-12/p40结合蛋白
KR20170078831A (ko) Cd3/cd38 t 세포 재표적화 헤테로-이량체성 면역글로불린 및 이들의 제조 방법