JP2010527911A5 - - Google Patents
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- Publication number
- JP2010527911A5 JP2010527911A5 JP2009554721A JP2009554721A JP2010527911A5 JP 2010527911 A5 JP2010527911 A5 JP 2010527911A5 JP 2009554721 A JP2009554721 A JP 2009554721A JP 2009554721 A JP2009554721 A JP 2009554721A JP 2010527911 A5 JP2010527911 A5 JP 2010527911A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- compound
- mmol
- pyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91971907P | 2007-03-23 | 2007-03-23 | |
| PCT/US2007/007444 WO2007117381A2 (en) | 2006-03-24 | 2007-03-23 | 2 -aminopyridine analogs as glucokinase activators |
| US60/919,719 | 2007-03-23 | ||
| USPCT/US2007/007444 | 2007-03-23 | ||
| US97426007P | 2007-09-21 | 2007-09-21 | |
| US60/974,260 | 2007-09-21 | ||
| PCT/US2008/057543 WO2008118718A2 (en) | 2007-03-23 | 2008-03-19 | 2-aminopyridine analogs as glucokinase activators |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010527911A JP2010527911A (ja) | 2010-08-19 |
| JP2010527911A5 true JP2010527911A5 (https=) | 2012-05-10 |
| JP5450108B2 JP5450108B2 (ja) | 2014-03-26 |
Family
ID=39711955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009554721A Expired - Fee Related JP5450108B2 (ja) | 2007-03-23 | 2008-03-19 | グルコキナーゼ活性化剤としての２−アミノピリジン類似体 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8362037B2 (https=) |
| EP (1) | EP2173745A2 (https=) |
| JP (1) | JP5450108B2 (https=) |
| CN (1) | CN101679405A (https=) |
| CA (1) | CA2681695A1 (https=) |
| TW (1) | TW200843765A (https=) |
| WO (1) | WO2008118718A2 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008091770A1 (en) * | 2007-01-24 | 2008-07-31 | Array Biopharma Inc. | 2-aminopyridine derivatives as glucokinase activators |
| EP2573087A1 (en) | 2007-09-21 | 2013-03-27 | Array Biopharma, Inc. | Pyridin-2-yl-amino-1,2,4-thiadiazole derivatives as glucokinase activators for the treatment of diabetes mellitus |
| BRPI0818658A2 (pt) | 2007-10-09 | 2015-04-14 | Merck Patent Ges Mit Beschränkter Haftung | Derivados de piridina úteis como ativadores de glicoquinase |
| CN101970432B (zh) * | 2008-01-25 | 2014-05-28 | 杜邦公司 | 杀真菌杂环化合物 |
| AR077821A1 (es) * | 2009-08-11 | 2011-09-28 | Sanofi Aventis Us Llc | Procedimiento para preparar hidrocloruro de 4-metil-3-tienilamina |
| WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| CN102959076B (zh) | 2010-03-31 | 2015-09-16 | 斯克里普斯研究所 | 重编程细胞 |
| EP2582709B1 (de) | 2010-06-18 | 2018-01-24 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| JPWO2012121314A1 (ja) | 2011-03-09 | 2014-07-17 | 第一三共株式会社 | ジピリジルアミン誘導体 |
| WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
| CA2877026A1 (en) | 2012-05-18 | 2013-11-21 | Amgen Inc. | Method for the preparation of thiadiazoles |
| ES2619708T3 (es) | 2013-03-13 | 2017-06-26 | VIIV Healthcare UK (No.5) Limited | Inhibidores de la replicación del virus de inmunodeficiencia humana |
| WO2014164467A1 (en) | 2013-03-13 | 2014-10-09 | Bristol-Myers Squibb Company | Inhibitors of human immunodeficiency virus replication |
| WO2015091645A1 (en) | 2013-12-18 | 2015-06-25 | Basf Se | Azole compounds carrying an imine-derived substituent |
| SG10202001065SA (en) | 2014-03-28 | 2020-04-29 | Azevan Pharmaceuticals Inc | Compositions and methods for treating neurodegenerative diseases |
| CN106349159B (zh) * | 2016-08-29 | 2019-03-22 | 山东省联合农药工业有限公司 | 一种3-氯-2-氰基-5-三氟甲基吡啶的制备方法 |
| CN107286087B (zh) * | 2017-04-16 | 2020-01-07 | 内蒙古佳瑞米精细化工有限公司 | 一种2-氰基-3-氯-5-三氟甲基吡啶的合成方法 |
| MX2020002762A (es) | 2017-09-15 | 2020-09-17 | Azevan Pharmaceuticals Inc | Composiciones y métodos para tratar una lesión cerebral. |
| SG11202003879RA (en) | 2017-10-30 | 2020-05-28 | Neuropore Therapies Inc | Substituted phenyl sulfonyl phenyl triazole thiones and uses thereof |
| WO2020051424A1 (en) | 2018-09-07 | 2020-03-12 | Pic Therapeutics | Eif4e inhibitors and uses thereof |
| EP4077276A1 (en) | 2019-12-19 | 2022-10-26 | Curia Spain S.A.U. | Process and intermediates for the preparation of upadacitinib |
| TW202146393A (zh) | 2020-03-03 | 2021-12-16 | 美商皮克醫療公司 | Eif4e抑制劑及其用途 |
| US12157732B2 (en) | 2021-08-25 | 2024-12-03 | PIC Therapeutics, Inc. | eIF4E inhibitors and uses thereof |
| CA3229560A1 (en) | 2021-08-25 | 2023-03-02 | Christopher L. Vandeusen | Eif4e inhibitors and uses thereof |
| WO2023212237A1 (en) | 2022-04-27 | 2023-11-02 | Skyhawk Therapeutics, Inc. | Compositions useful for modulating splicing |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3703435A1 (de) * | 1987-02-05 | 1988-08-18 | Thomae Gmbh Dr K | Neue thiazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5260311A (en) * | 1989-02-22 | 1993-11-09 | Novo Nordisk A/S | Piperidine compounds and their use |
| NZ540791A (en) * | 2003-02-13 | 2009-09-25 | Banyu Pharma Co Ltd | Novel 2-pyridinecarboxamide derivatives |
| AR049418A1 (es) | 2004-02-27 | 2006-08-02 | Bayer Pharmaceuticals Corp | Derivados de heteroarilaminopirazol y composiciones farmaceuticas para el tratamiento de la diabetes. |
| US7687502B2 (en) | 2004-03-23 | 2010-03-30 | Banyu Pharmaceutical Co., Ltd. | Substituted quinazoline or pyridopyrimidine derivative |
| NZ567858A (en) * | 2005-11-01 | 2011-08-26 | Array Biopharma Inc | Pyridine compounds useful as Glucokinase activators |
| CN101437512A (zh) * | 2006-01-27 | 2009-05-20 | 阿雷生物药品公司 | 葡萄糖激酶活化剂 |
| RU2457207C2 (ru) * | 2006-03-24 | 2012-07-27 | Эррэй Биофарма Инк. | Активаторы глюкокиназы |
-
2008
- 2008-03-19 CA CA002681695A patent/CA2681695A1/en not_active Abandoned
- 2008-03-19 WO PCT/US2008/057543 patent/WO2008118718A2/en not_active Ceased
- 2008-03-19 JP JP2009554721A patent/JP5450108B2/ja not_active Expired - Fee Related
- 2008-03-19 CN CN200880017007A patent/CN101679405A/zh active Pending
- 2008-03-19 EP EP08732495A patent/EP2173745A2/en not_active Withdrawn
- 2008-03-19 US US12/532,374 patent/US8362037B2/en not_active Expired - Fee Related
- 2008-03-21 TW TW097110307A patent/TW200843765A/zh unknown
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| JP2010527911A5 (https=) | ||
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| US8431713B2 (en) | 2-aminopyridine derivatives as glucokinase activators | |
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