JP2010513483A5 - - Google Patents

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Publication number
JP2010513483A5
JP2010513483A5 JP2009542815A JP2009542815A JP2010513483A5 JP 2010513483 A5 JP2010513483 A5 JP 2010513483A5 JP 2009542815 A JP2009542815 A JP 2009542815A JP 2009542815 A JP2009542815 A JP 2009542815A JP 2010513483 A5 JP2010513483 A5 JP 2010513483A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
salt
sosoroid
bisphosphonate drug
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009542815A
Other languages
English (en)
Japanese (ja)
Other versions
JP5492564B2 (ja
JP2010513483A (ja
Filing date
Publication date
Priority claimed from US11/768,181 external-priority patent/US8974801B2/en
Application filed filed Critical
Publication of JP2010513483A publication Critical patent/JP2010513483A/ja
Publication of JP2010513483A5 publication Critical patent/JP2010513483A5/ja
Application granted granted Critical
Publication of JP5492564B2 publication Critical patent/JP5492564B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009542815A 2006-12-21 2007-12-13 ビスホスホネートの水性懸濁液を含む長期徐放性医薬組成物 Expired - Fee Related JP5492564B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US87680006P 2006-12-21 2006-12-21
US60/876,800 2006-12-21
US11/768,181 2007-06-25
US11/768,181 US8974801B2 (en) 2006-12-21 2007-06-25 Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate
PCT/US2007/025569 WO2008085281A1 (en) 2006-12-21 2007-12-13 Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate

Publications (3)

Publication Number Publication Date
JP2010513483A JP2010513483A (ja) 2010-04-30
JP2010513483A5 true JP2010513483A5 (enExample) 2011-06-23
JP5492564B2 JP5492564B2 (ja) 2014-05-14

Family

ID=39543732

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009542815A Expired - Fee Related JP5492564B2 (ja) 2006-12-21 2007-12-13 ビスホスホネートの水性懸濁液を含む長期徐放性医薬組成物

Country Status (14)

Country Link
US (3) US8974801B2 (enExample)
EP (2) EP2548441B1 (enExample)
JP (1) JP5492564B2 (enExample)
CN (1) CN101616591B (enExample)
BR (1) BRPI0720605A2 (enExample)
CA (1) CA2673058C (enExample)
DK (2) DK2120585T3 (enExample)
ES (2) ES2396733T3 (enExample)
MX (1) MX2009006447A (enExample)
PL (2) PL2548441T3 (enExample)
PT (2) PT2120585E (enExample)
RU (1) RU2453316C2 (enExample)
SI (1) SI2120585T1 (enExample)
WO (1) WO2008085281A1 (enExample)

Families Citing this family (14)

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KR101813728B1 (ko) * 2009-07-31 2017-12-29 그뤼넨탈 게엠베하 결정화 방법 및 생체이용률
US20160016982A1 (en) 2009-07-31 2016-01-21 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
US9169279B2 (en) 2009-07-31 2015-10-27 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
AU2010330909B2 (en) 2009-12-18 2014-09-11 Howmedica Osteonics Corp. Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
CN102453050B (zh) * 2010-11-03 2015-01-07 成都云克药业有限责任公司 一种二膦酸化合物及其制备方法
ES2714701T3 (es) 2010-11-10 2019-05-29 Stryker European Holdings I Llc Proceso para la preparación de una espuma ósea polimérica
WO2012071517A2 (en) 2010-11-24 2012-05-31 Thar Pharmaceuticals, Inc. Novel crystalline forms
WO2013175385A1 (en) 2012-05-20 2013-11-28 Bar-Ilan Research And Development Company Ltd. Bisphosphonates vinylic monomers and polymers and uses thereof
US9492268B2 (en) 2012-11-13 2016-11-15 The Secant Group, Llc Tapered tubular implant formed from woven fabric
WO2017208070A1 (en) 2016-05-31 2017-12-07 Grünenthal GmbH Bisphosphonic acid and coformers with lysin, glycin, nicotinamide for treating psoriatic arthritis
CN108815117A (zh) * 2018-08-23 2018-11-16 宁波蒙曼生物科技有限公司 一种镇痛药物组合物及其制备方法
CN109930209B (zh) * 2019-03-07 2022-02-15 华南理工大学 一种具高结晶度及长径比双膦酸盐晶体及其制备方法
CN112707934A (zh) * 2020-12-30 2021-04-27 华南理工大学 一种阿仑膦酸钙配合物及其制备方法
CN114349786B (zh) * 2021-12-28 2023-07-11 中国科学院上海硅酸盐研究所 阿仑膦酸钙超长纳米线及其制备方法和应用

Family Cites Families (23)

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US5356887A (en) 1990-01-31 1994-10-18 Merck & Co., Inc. Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids
US5358941A (en) 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
WO1995008304A1 (en) * 1993-09-21 1995-03-30 The Penn State Research Foundation Bone substitute composition comprising hydroxyapatite and a method of production therefor
US5462932A (en) 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
ES2221019T3 (es) 1996-10-31 2004-12-16 Takeda Chemical Industries, Ltd. Preparacion de liberacion mantenida.
EP1028712B1 (en) 1997-09-19 2005-01-12 Shire Laboratories Inc. Solid solution beadlet
SE9703691D0 (sv) 1997-10-10 1997-10-10 Astra Ab Pharmaceutical compositions
WO1999067809A1 (en) 1998-06-24 1999-12-29 Merck & Co., Inc. Compositions and methods for inhibiting bone resorption
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6677320B2 (en) 2000-01-20 2004-01-13 Hoffmann-La Roches Inc. Parenteral bisphosphonate composition with improved local tolerance
KR100492110B1 (ko) * 2000-05-05 2005-06-02 에프. 호프만-라 로슈 아게 비스포스폰산 또는 그의 염을 포함하는 피하 투여용겔-유사 약학 조성물
US6350471B1 (en) 2000-05-31 2002-02-26 Pharma Pass Llc Tablet comprising a delayed release coating
US6476006B2 (en) 2000-06-23 2002-11-05 Teva Pharmaceutical Industries, Ltd. Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates
JP4161031B2 (ja) 2000-10-31 2008-10-08 独立行政法人産業技術総合研究所 亜鉛含有リン酸カルシウム微粒子含有懸濁液または粒子溶媒混合系及び亜鉛欠乏症治療剤
GB0029111D0 (en) 2000-11-29 2001-01-10 Novartis Ag Organic compounds
US6558702B2 (en) 2001-04-13 2003-05-06 Alkermes Controlled Therapeutics, Inc. Method of modifying the release profile of sustained release compositions
FR2836681B1 (fr) 2002-03-04 2004-06-18 Centre Nat Rech Scient Compose phosphocalcique modifie, composition injectable le contenant
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
JP2007501241A (ja) 2003-08-06 2007-01-25 ローディア インコーポレイティド 骨成長を促進する方法
US7420000B2 (en) 2003-09-10 2008-09-02 University Of Southern California Amino phosphonate and amino bis-phosphonate derivatives
US20050261250A1 (en) 2004-05-19 2005-11-24 Merck & Co., Inc., Compositions and methods for inhibiting bone resorption
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation

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