DK2120585T3 - Langtidsfrigivet farmaceutisk sammensætning indeholdende vandig opløsning af bisfosfonat - Google Patents

Langtidsfrigivet farmaceutisk sammensætning indeholdende vandig opløsning af bisfosfonat

Info

Publication number
DK2120585T3
DK2120585T3 DK07862893.0T DK07862893T DK2120585T3 DK 2120585 T3 DK2120585 T3 DK 2120585T3 DK 07862893 T DK07862893 T DK 07862893T DK 2120585 T3 DK2120585 T3 DK 2120585T3
Authority
DK
Denmark
Prior art keywords
bisphosphonate
long
aqueous solution
pharmaceutical composition
composition containing
Prior art date
Application number
DK07862893.0T
Other languages
English (en)
Inventor
Jack Yongfeng Zhang
Mary Ziping Luo
Dingyuan Fei
Kevin Xie
Jie Fei Ding
Original Assignee
Amphastar Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amphastar Pharmaceuticals Inc filed Critical Amphastar Pharmaceuticals Inc
Application granted granted Critical
Publication of DK2120585T3 publication Critical patent/DK2120585T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK07862893.0T 2006-12-21 2007-12-13 Langtidsfrigivet farmaceutisk sammensætning indeholdende vandig opløsning af bisfosfonat DK2120585T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87680006P 2006-12-21 2006-12-21
US11/768,181 US8974801B2 (en) 2006-12-21 2007-06-25 Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate
PCT/US2007/025569 WO2008085281A1 (en) 2006-12-21 2007-12-13 Long term sustained release pharmaceutical composition containing aqueous suspension of bisphosphonate

Publications (1)

Publication Number Publication Date
DK2120585T3 true DK2120585T3 (da) 2013-01-21

Family

ID=39543732

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07862893.0T DK2120585T3 (da) 2006-12-21 2007-12-13 Langtidsfrigivet farmaceutisk sammensætning indeholdende vandig opløsning af bisfosfonat
DK12186963.0T DK2548441T3 (da) 2006-12-21 2007-12-13 Langtidsvarende frisætning af farmaceutisk sammensætning indeholdende vandig opslæmning af bisphosphonat

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK12186963.0T DK2548441T3 (da) 2006-12-21 2007-12-13 Langtidsvarende frisætning af farmaceutisk sammensætning indeholdende vandig opslæmning af bisphosphonat

Country Status (14)

Country Link
US (3) US8974801B2 (da)
EP (2) EP2548441B1 (da)
JP (1) JP5492564B2 (da)
CN (1) CN101616591B (da)
BR (1) BRPI0720605A2 (da)
CA (1) CA2673058C (da)
DK (2) DK2120585T3 (da)
ES (2) ES2524690T3 (da)
MX (1) MX2009006447A (da)
PL (2) PL2120585T3 (da)
PT (2) PT2548441E (da)
RU (1) RU2453316C2 (da)
SI (1) SI2120585T1 (da)
WO (1) WO2008085281A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9169279B2 (en) 2009-07-31 2015-10-27 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
US20160016982A1 (en) 2009-07-31 2016-01-21 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
JP5852569B2 (ja) 2009-07-31 2016-02-03 タール ファーマシューティカルズ，インコーポレイテッド 結晶化方法および生物学的利用能
US8481065B2 (en) * 2009-12-18 2013-07-09 Howmedica Osteonics Corp. Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
CN102453050B (zh) * 2010-11-03 2015-01-07 成都云克药业有限责任公司 一种二膦酸化合物及其制备方法
ES2714701T3 (es) 2010-11-10 2019-05-29 Stryker European Holdings I Llc Proceso para la preparación de una espuma ósea polimérica
US9340565B2 (en) 2010-11-24 2016-05-17 Thar Pharmaceuticals, Inc. Crystalline forms
US9884880B2 (en) 2012-05-20 2018-02-06 Bar-Ilan University Bisphosphonates vinylic monomers and polymers and uses thereof
US9492268B2 (en) 2012-11-13 2016-11-15 The Secant Group, Llc Tapered tubular implant formed from woven fabric
WO2017208070A1 (en) 2016-05-31 2017-12-07 Grünenthal GmbH Bisphosphonic acid and coformers with lysin, glycin, nicotinamide for treating psoriatic arthritis
CN108815117A (zh) * 2018-08-23 2018-11-16 宁波蒙曼生物科技有限公司 一种镇痛药物组合物及其制备方法
CN109930209B (zh) * 2019-03-07 2022-02-15 华南理工大学 一种具高结晶度及长径比双膦酸盐晶体及其制备方法
CN112707934A (zh) * 2020-12-30 2021-04-27 华南理工大学 一种阿仑膦酸钙配合物及其制备方法
CN114349786B (zh) * 2021-12-28 2023-07-11 中国科学院上海硅酸盐研究所 阿仑膦酸钙超长纳米线及其制备方法和应用

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US5356887A (en) 1990-01-31 1994-10-18 Merck & Co., Inc. Pharmaceutical compositions containing insoluble calcium salts of amino-hydroxybutylidene bisphoshonic acids
US5358941A (en) 1992-12-02 1994-10-25 Merck & Co., Inc. Dry mix formulation for bisphosphonic acids with lactose
US6201039B1 (en) * 1993-09-21 2001-03-13 The Penn State Research Foundation Bone substitute composition comprising hydroxyapatite and a method of production therefor
US5462932A (en) 1994-05-17 1995-10-31 Merck & Co., Inc. Oral liquid alendronate formulations
ATE272394T1 (de) 1996-10-31 2004-08-15 Takeda Chemical Industries Ltd Zubereitung mit verzögerter freisetzung
AU9496798A (en) 1997-09-19 1999-04-05 Shire Laboratories, Inc. Solid solution beadlet
SE9703691D0 (sv) 1997-10-10 1997-10-10 Astra Ab Pharmaceutical compositions
EP1088333A4 (en) 1998-06-24 2005-08-10 Merck & Co Inc METHOD AND COMPOSITIONS FOR CONNECTING OSTEOPROSIS
US6342249B1 (en) 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6677320B2 (en) 2000-01-20 2004-01-13 Hoffmann-La Roches Inc. Parenteral bisphosphonate composition with improved local tolerance
JP3923800B2 (ja) * 2000-05-05 2007-06-06 エフ．ホフマン−ラ ロシュ アーゲー ビスホスホン酸またはそれらの塩を含む、皮下投与のためのゲル様医薬組成物
US6350471B1 (en) 2000-05-31 2002-02-26 Pharma Pass Llc Tablet comprising a delayed release coating
US6476006B2 (en) 2000-06-23 2002-11-05 Teva Pharmaceutical Industries, Ltd. Composition and dosage form for delayed gastric release of alendronate and/or other bis-phosphonates
JP4161031B2 (ja) 2000-10-31 2008-10-08 独立行政法人産業技術総合研究所 亜鉛含有リン酸カルシウム微粒子含有懸濁液または粒子溶媒混合系及び亜鉛欠乏症治療剤
GB0029111D0 (en) 2000-11-29 2001-01-10 Novartis Ag Organic compounds
US6558702B2 (en) 2001-04-13 2003-05-06 Alkermes Controlled Therapeutics, Inc. Method of modifying the release profile of sustained release compositions
FR2836681B1 (fr) 2002-03-04 2004-06-18 Centre Nat Rech Scient Compose phosphocalcique modifie, composition injectable le contenant
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
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US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation

Also Published As

Publication number Publication date
SI2120585T1 (sl) 2013-05-31
CN101616591B (zh) 2014-06-18
RU2453316C2 (ru) 2012-06-20
EP2120585B1 (en) 2012-10-03
ES2396733T3 (es) 2013-02-25
US20150157649A1 (en) 2015-06-11
WO2008085281A1 (en) 2008-07-17
CN101616591A (zh) 2009-12-30
JP2010513483A (ja) 2010-04-30
US8974801B2 (en) 2015-03-10
US20080153784A1 (en) 2008-06-26
PT2120585E (pt) 2013-01-15
PL2548441T3 (pl) 2015-02-27
ES2524690T3 (es) 2014-12-11
PT2548441E (pt) 2014-11-27
EP2548441A1 (en) 2013-01-23
PL2120585T3 (pl) 2013-03-29
BRPI0720605A2 (pt) 2014-04-08
MX2009006447A (es) 2009-07-27
CA2673058A1 (en) 2008-07-17
RU2009128023A (ru) 2011-01-27
EP2120585A4 (en) 2011-11-23
JP5492564B2 (ja) 2014-05-14
US20150157650A1 (en) 2015-06-11
CA2673058C (en) 2015-11-24
EP2548441B1 (en) 2014-08-27
DK2548441T3 (da) 2014-12-08
EP2120585A1 (en) 2009-11-25

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