JP2010510976A5 - - Google Patents
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- Publication number
- JP2010510976A5 JP2010510976A5 JP2009537744A JP2009537744A JP2010510976A5 JP 2010510976 A5 JP2010510976 A5 JP 2010510976A5 JP 2009537744 A JP2009537744 A JP 2009537744A JP 2009537744 A JP2009537744 A JP 2009537744A JP 2010510976 A5 JP2010510976 A5 JP 2010510976A5
- Authority
- JP
- Japan
- Prior art keywords
- thiazolidin
- hydroxy
- benz
- ylidene
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2006054409 | 2006-11-23 | ||
| PCT/IB2007/054752 WO2008062376A2 (en) | 2006-11-23 | 2007-11-22 | New process for the preparation of 2-imino-thiazolidin-4-one derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010510976A JP2010510976A (ja) | 2010-04-08 |
| JP2010510976A5 true JP2010510976A5 (https=) | 2010-05-20 |
| JP4669564B2 JP4669564B2 (ja) | 2011-04-13 |
Family
ID=39316391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009537744A Active JP4669564B2 (ja) | 2006-11-23 | 2007-11-22 | ２−イミノ−チアゾリジン−４−オン誘導体の製造のための新規な方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8263780B2 (https=) |
| EP (2) | EP2094676B1 (https=) |
| JP (1) | JP4669564B2 (https=) |
| KR (1) | KR101255879B1 (https=) |
| CN (2) | CN101541772B (https=) |
| AU (1) | AU2007323042B2 (https=) |
| CA (1) | CA2669069C (https=) |
| DK (2) | DK2094676T3 (https=) |
| ES (2) | ES2523401T3 (https=) |
| IL (1) | IL198847A (https=) |
| MX (1) | MX2009005048A (https=) |
| TW (1) | TWI460166B (https=) |
| WO (1) | WO2008062376A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE43728E1 (en) | 2003-11-21 | 2012-10-09 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| USRE43833E1 (en) | 2003-11-21 | 2012-11-27 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| US8912340B2 (en) | 2006-11-23 | 2014-12-16 | Actelion Pharmaceuticals Ltd. | Process for the preparation of 2-imino-thiazolidin-4-one derivatives |
| PL2278960T5 (pl) | 2008-03-17 | 2020-06-29 | Actelion Pharmaceuticals Ltd. | Schemat dawkowania dla selektywnego agonisty receptora sip1 |
| GB0819182D0 (en) | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
| SMT202000298T1 (it) * | 2012-08-17 | 2020-07-08 | Actelion Pharmaceuticals Ltd | Processo per la produzione di (2z,5z)-5-(3-cloro-4((r)-2,3-diidrossipropossi) benziliden)-2-(propilimmino)-3-(o-tolil)tiazolidin-4-one e intermedio usato in detto processo |
| MA41139B1 (fr) | 2014-12-11 | 2026-02-27 | Laboratoires Juvise Pharmaceuticals | Combinaison pharmaceutique comprenant du ponesimod et son utilisation dans le traitement de la sclérose en plaque |
| KR20200013086A (ko) | 2014-12-11 | 2020-02-05 | 액테리온 파마슈티칼 리미티드 | 선택적 s1p1 수용체 효능제에 대한 투약 섭생 |
| JOP20190207A1 (ar) | 2017-03-14 | 2019-09-10 | Actelion Pharmaceuticals Ltd | تركيبة صيدلانية تشتمل على بونيسيمود |
| EP3684358A4 (en) | 2017-09-19 | 2021-01-13 | Teva Pharmaceuticals International GmbH | NEW CRYSTALLINE POLYMORPHIC SHAPE OF PONESIMOD |
| US11186556B1 (en) | 2018-10-16 | 2021-11-30 | Celgene Corporation | Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof |
| US11014897B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof |
| US11014940B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Thiazolidinone and oxazolidinone compounds and formulations |
| US11013723B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms of a thiazolidinone compound, compositions and methods of use thereof |
| KR20220034151A (ko) * | 2019-07-10 | 2022-03-17 | 바이엘 악티엔게젤샤프트 | 2-(페닐이미노)-1,3-티아졸리딘-4-온의 제조 방법 |
| BR112022000185A2 (pt) * | 2019-07-10 | 2022-02-22 | Bayer Ag | Método de preparação de 2-(fenilimino)-1,3-tiazolidin-4-onas |
| JP7749552B2 (ja) | 2019-10-31 | 2025-10-06 | イドルシア・ファーマシューティカルズ・リミテッド | Ｃｘｃｒ７アンタゴニストのｓ１ｐ１受容体調節剤との合剤 |
| KR20200019639A (ko) | 2020-01-30 | 2020-02-24 | 전대연 | 만남의 스마트 도착시스템 |
| IL295464A (en) * | 2020-02-18 | 2022-10-01 | Bayer Ag | Process of preparing 2-(phenylimino)-3-alkyl-1,3-thiazolidin-4-ones |
| EP4387960A1 (en) | 2021-08-17 | 2024-06-26 | Teva Czech Industries s.r.o | Polymorphs of ponesimod |
| EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
| WO2023152691A1 (en) * | 2022-02-10 | 2023-08-17 | Metrochem Api Pvt Ltd | Process for the preparation of ponesimod and its intermediates thereof |
| CN117924210B (zh) * | 2024-01-22 | 2026-04-03 | 赣南师范大学 | 一种2-亚氨基噻唑烷-4-酮类化合物的制备方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3077402A (en) * | 1954-12-06 | 1963-02-12 | Polaroid Corp | Photographic color processes, products, and compositions |
| NL270002A (https=) | 1960-10-08 | |||
| OA03835A (fr) * | 1970-07-17 | 1971-12-24 | Rhone Poulenc Sa | Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent. |
| PT97507B (pt) | 1990-04-27 | 1998-08-31 | Orion Yhtymae Oy | Processo para apreparacao de novos derivados de catecol farmacologicamente activos |
| TW221689B (https=) * | 1991-08-27 | 1994-03-11 | Otsuka Pharma Co Ltd | |
| EP0638075B1 (en) * | 1993-02-26 | 2002-01-16 | Otsuka Pharmaceutical Co., Ltd. | Thiazole or imidazole derivatives as maillard reaction inhibitors |
| KR960022486A (ko) | 1994-12-29 | 1996-07-18 | 김준웅 | 신규 티아졸리딘-4-온 유도체 |
| WO2001036402A1 (en) * | 1998-07-14 | 2001-05-25 | Fujimoto Brothers Co., Ltd. | Novel 2-(n-cyanoimino)thiazolidin-4-one derivatives |
| US6353006B1 (en) * | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
| CN1247553C (zh) | 1999-09-14 | 2006-03-29 | 盐野义制药株式会社 | 2－亚氨基－1,3－噻嗪衍生物 |
| US20050019825A9 (en) * | 2002-03-15 | 2005-01-27 | Qing Dong | Common ligand mimics: pseudothiohydantoins |
| JP4782564B2 (ja) | 2002-07-10 | 2011-09-28 | メルク セローノ ソシエテ アノニム | アゾリジノン−ビニル縮合−ベンゼン誘導体 |
| GB0217152D0 (en) | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
| CN100579978C (zh) * | 2002-11-22 | 2010-01-13 | 史密丝克莱恩比彻姆公司 | 化合物 |
| US20040167192A1 (en) | 2003-01-16 | 2004-08-26 | David Solow-Cordero | Methods of treating conditions associated with an Edg-7 receptor |
| USRE43728E1 (en) | 2003-11-21 | 2012-10-09 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| EP1718642A4 (en) * | 2004-02-25 | 2010-11-24 | Glaxosmithkline Llc | NEW CHEMICAL COMPOUNDS |
| WO2006094233A1 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | N,n'-dicyclic isothiourea sirtuin modulators |
| PL2278960T5 (pl) | 2008-03-17 | 2020-06-29 | Actelion Pharmaceuticals Ltd. | Schemat dawkowania dla selektywnego agonisty receptora sip1 |
| GB0819182D0 (en) | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
-
2007
- 2007-11-22 TW TW096144311A patent/TWI460166B/zh active
- 2007-11-22 ES ES12000613.5T patent/ES2523401T3/es active Active
- 2007-11-22 DK DK07849225.3T patent/DK2094676T3/da active
- 2007-11-22 JP JP2009537744A patent/JP4669564B2/ja active Active
- 2007-11-22 DK DK12000613.5T patent/DK2489662T3/da active
- 2007-11-22 EP EP07849225.3A patent/EP2094676B1/en active Active
- 2007-11-22 AU AU2007323042A patent/AU2007323042B2/en active Active
- 2007-11-22 US US12/516,055 patent/US8263780B2/en active Active
- 2007-11-22 ES ES07849225T patent/ES2410793T3/es active Active
- 2007-11-22 KR KR1020097011745A patent/KR101255879B1/ko active Active
- 2007-11-22 CA CA2669069A patent/CA2669069C/en active Active
- 2007-11-22 CN CN2007800431941A patent/CN101541772B/zh active Active
- 2007-11-22 WO PCT/IB2007/054752 patent/WO2008062376A2/en not_active Ceased
- 2007-11-22 CN CN2012105461683A patent/CN103087004A/zh active Pending
- 2007-11-22 EP EP12000613.5A patent/EP2489662B1/en active Active
- 2007-11-22 MX MX2009005048A patent/MX2009005048A/es active IP Right Grant
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2009
- 2009-05-20 IL IL198847A patent/IL198847A/en active IP Right Grant