JP2010509234A - 新生物疾患、自己免疫疾患および炎症性疾患を処置する方法 - Google Patents

新生物疾患、自己免疫疾患および炎症性疾患を処置する方法 Download PDF

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JP2010509234A
JP2010509234A JP2009535486A JP2009535486A JP2010509234A JP 2010509234 A JP2010509234 A JP 2010509234A JP 2009535486 A JP2009535486 A JP 2009535486A JP 2009535486 A JP2009535486 A JP 2009535486A JP 2010509234 A JP2010509234 A JP 2010509234A
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antibody
patient
cells
leukemia
binding
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JP2010509234A5 (enExample
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ジョナサン ジー. ドラックマン,
メイ キュング サザーランド,
エリック ジーバース,
グラント リスドン,
エゾゲリン オフラゾグリュ,
アラン ワール,
ティム ルイス,
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シアトル ジェネティックス, インコーポレイテッド
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
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    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P35/00Antineoplastic agents
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    • A61P35/00Antineoplastic agents
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    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • A61P37/08Antiallergic agents
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]

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JP2009535486A 2006-11-02 2007-11-02 新生物疾患、自己免疫疾患および炎症性疾患を処置する方法 Pending JP2010509234A (ja)

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US85653006P 2006-11-02 2006-11-02
US87443906P 2006-12-11 2006-12-11
US94302107P 2007-06-08 2007-06-08
PCT/US2007/083508 WO2008058021A2 (en) 2006-11-02 2007-11-02 Methods of treating neoplastic, autoimmune and inflammatory diseases

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US (3) US20110038856A1 (enExample)
EP (1) EP2084527A4 (enExample)
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AU (1) AU2007317333A1 (enExample)
CA (1) CA2667808A1 (enExample)
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CN106794266A (zh) * 2014-07-01 2017-05-31 安普希韦纳治疗公司 双特异性cd33和cd3结合蛋白
JP2018533909A (ja) * 2015-08-28 2018-11-22 アムニクス オペレーティング インコーポレイテッド キメラポリペプチドアセンブリーならびにそれを作製および使用する方法
US10738118B2 (en) 2015-05-29 2020-08-11 Amphivena Therapeutics, Inc. Methods of using bispecific CD33 and CD3 binding proteins

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Cited By (12)

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CN106794266A (zh) * 2014-07-01 2017-05-31 安普希韦纳治疗公司 双特异性cd33和cd3结合蛋白
JP2017521415A (ja) * 2014-07-01 2017-08-03 アンフィヴェナ セラピューティクス,インク. 二重特異性cd33およびcd3結合タンパク質
US10626190B2 (en) 2014-07-01 2020-04-21 Amphivena Therapeutics, Inc. Bispecific CD33 and CD3 binding proteins
CN106794266B (zh) * 2014-07-01 2021-02-23 安普希韦纳治疗公司 双特异性cd33和cd3结合蛋白
CN112851820A (zh) * 2014-07-01 2021-05-28 安普希韦纳治疗公司 双特异性cd33和cd3结合蛋白
JP2022068346A (ja) * 2014-07-01 2022-05-09 アンフィヴェナ セラピューティクス,インク. 二重特異性cd33およびcd3結合タンパク質
CN112851820B (zh) * 2014-07-01 2023-11-28 安普希韦纳治疗公司 双特异性cd33和cd3结合蛋白
US10738118B2 (en) 2015-05-29 2020-08-11 Amphivena Therapeutics, Inc. Methods of using bispecific CD33 and CD3 binding proteins
US11753469B2 (en) 2015-05-29 2023-09-12 Anji Bruno, Llc Methods of using bispecific CD33 and CD3 binding proteins
JP2018533909A (ja) * 2015-08-28 2018-11-22 アムニクス オペレーティング インコーポレイテッド キメラポリペプチドアセンブリーならびにそれを作製および使用する方法
JP2021178831A (ja) * 2015-08-28 2021-11-18 アムニクス ファーマシューティカルズ, インコーポレイテッド キメラポリペプチドアセンブリーならびにそれを作製および使用する方法
JP2024105275A (ja) * 2015-08-28 2024-08-06 アムニクス ファーマシューティカルズ, インコーポレイテッド キメラポリペプチドアセンブリーならびにそれを作製および使用する方法

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