JP2010509232A - 高甘味度甘味料を含む抗糖尿病組成物 - Google Patents

高甘味度甘味料を含む抗糖尿病組成物 Download PDF

Info

Publication number
JP2010509232A
JP2010509232A JP2009535474A JP2009535474A JP2010509232A JP 2010509232 A JP2010509232 A JP 2010509232A JP 2009535474 A JP2009535474 A JP 2009535474A JP 2009535474 A JP2009535474 A JP 2009535474A JP 2010509232 A JP2010509232 A JP 2010509232A
Authority
JP
Japan
Prior art keywords
composition
sweet taste
taste improving
acid
polyol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009535474A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010509232A5 (https=
Inventor
プラカーシャ,インドラ
デュボワ,グラント,イー.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coca Cola Co
Original Assignee
Coca Cola Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coca Cola Co filed Critical Coca Cola Co
Publication of JP2010509232A publication Critical patent/JP2010509232A/ja
Publication of JP2010509232A5 publication Critical patent/JP2010509232A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30Artificial sweetening agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2009535474A 2006-11-02 2007-11-01 高甘味度甘味料を含む抗糖尿病組成物 Pending JP2010509232A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/555,825 US20080107787A1 (en) 2006-11-02 2006-11-02 Anti-Diabetic Composition with High-Potency Sweetener
PCT/US2007/083379 WO2008057968A2 (en) 2006-11-02 2007-11-01 Anti-diabetic composition with high-potency sweetener

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014068979A Division JP2014139224A (ja) 2006-11-02 2014-03-28 高甘味度甘味料を含む抗糖尿病組成物

Publications (2)

Publication Number Publication Date
JP2010509232A true JP2010509232A (ja) 2010-03-25
JP2010509232A5 JP2010509232A5 (https=) 2010-12-16

Family

ID=39271596

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2009535474A Pending JP2010509232A (ja) 2006-11-02 2007-11-01 高甘味度甘味料を含む抗糖尿病組成物
JP2014068979A Pending JP2014139224A (ja) 2006-11-02 2014-03-28 高甘味度甘味料を含む抗糖尿病組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2014068979A Pending JP2014139224A (ja) 2006-11-02 2014-03-28 高甘味度甘味料を含む抗糖尿病組成物

Country Status (6)

Country Link
US (1) US20080107787A1 (https=)
EP (1) EP2091356A2 (https=)
JP (2) JP2010509232A (https=)
CN (1) CN101568266A (https=)
AU (1) AU2007317372A1 (https=)
WO (1) WO2008057968A2 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011182684A (ja) * 2010-03-05 2011-09-22 Ito En Ltd カルシウム含有無果汁炭酸飲料
JP2013116056A (ja) * 2011-12-01 2013-06-13 Healthy Sweet:Kk チョコレート
JP2014506460A (ja) * 2011-01-25 2014-03-17 モネル ケミカル センシズ センター 甘味を提供若しくは調整するための組成物および方法ならびにそれらのスクリーニング方法
JP2014093981A (ja) * 2012-11-09 2014-05-22 Mc Food Specialties Inc 飲食品の甘味の味質改善方法
JP2014529994A (ja) * 2011-09-15 2014-11-17 シージェイ チェイルジェダング コーポレイション 遅消化性成分を含有する糖尿改善用甘味素材組成物
JP2016163580A (ja) * 2011-01-28 2016-09-08 テート アンド ライル イングリーディエンツ アメリカズ エルエルシー レバウディオサイドbを含有するステビアブレンド

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943185B1 (en) 2007-03-16 2011-05-17 Pom Wonderful, Llc Method and composition for producing a stable and deodorized form of pomegranate seed oil
US8318459B2 (en) 2011-02-17 2012-11-27 Purecircle Usa Glucosyl stevia composition
US9392799B2 (en) 2011-02-17 2016-07-19 Purecircle Sdn Bhd Glucosyl stevia composition
US9386797B2 (en) 2011-02-17 2016-07-12 Purecircle Sdn Bhd Glucosyl stevia composition
US8334006B2 (en) 2005-10-11 2012-12-18 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US9107436B2 (en) 2011-02-17 2015-08-18 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
US8790730B2 (en) 2005-10-11 2014-07-29 Purecircle Usa Process for manufacturing a sweetener and use thereof
US8257948B1 (en) 2011-02-17 2012-09-04 Purecircle Usa Method of preparing alpha-glucosyl Stevia composition
US8337927B2 (en) * 2005-10-11 2012-12-25 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8889199B1 (en) 2007-02-07 2014-11-18 Pom Wonderful Llc Method and composition for producing a stable and deodorized form of pomegranate seed oil
US9877500B2 (en) * 2007-03-14 2018-01-30 Concentrate Manufacturing Company Of Ireland Natural beverage products
US8277862B2 (en) 2007-03-14 2012-10-02 Concentrate Manufacturing Company Of Ireland Beverage products having steviol glycosides and at least one acid
US8029846B2 (en) * 2007-03-14 2011-10-04 The Concentrate Manufacturing Company Of Ireland Beverage products
US20080226788A1 (en) * 2007-03-14 2008-09-18 Concentrate Manufacturing Company Of Ireland Lhg compositions for reducing lingering bitter taste of steviol glycosides
US20080226802A1 (en) * 2007-03-14 2008-09-18 Concentrate Manufacturing Company Of Ireland Beverage having natural sweeteners with one or more stevia components and source of berry
US8277861B2 (en) * 2007-03-14 2012-10-02 Concentrate Manufacturing Company Of Ireland Beverage products having steviol glycosides and at least one acid
TWI468167B (zh) * 2007-11-16 2015-01-11 威佛(國際)股份有限公司 藥學組成物
MY159747A (en) * 2008-10-28 2017-01-31 Univ Putra Malaysia Uses of curculigo latifolia (c. latifolia) extracts
RU2484827C2 (ru) 2008-11-04 2013-06-20 Юниверсити Оф Кентукки Рисерч Фаундэйшн Композиции на основе d-тагатозы и способы предупреждения и лечения атеросклероза, метаболического синдрома и их симптомов
US8158683B2 (en) * 2009-03-02 2012-04-17 Fhg Corporation Dietary supplements containing extracts of aronia and methods of using same to promote weight loss
US8828953B2 (en) 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
US9901551B2 (en) 2009-04-20 2018-02-27 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
CN102481276A (zh) * 2009-04-20 2012-05-30 埃尔舍利克斯治疗公司 基于化学感受受体配体的治疗法
EP2826386B1 (en) 2009-06-16 2022-12-28 Sweet Green Fields International Co., Limited Stevia composition comprising rebaudioside A and D
US10888099B2 (en) 2009-11-12 2021-01-12 Purecircle Sdn Bhd. Granulation of a Stevia sweetener
EP3461342A1 (en) 2009-11-12 2019-04-03 PureCircle USA Inc. Granulation of a stevia sweetener
US20110144006A1 (en) * 2009-12-15 2011-06-16 Igelosa Life Science Ab Protein composition
AU2010331939B2 (en) * 2009-12-18 2013-10-03 Stokely-Van Camp, Inc. Protein recovery beverage
US20110189360A1 (en) * 2010-02-04 2011-08-04 Pepsico, Inc. Method to Increase Solubility Limit of Rebaudioside D in an Aqueous Solution
US10696706B2 (en) 2010-03-12 2020-06-30 Purecircle Usa Inc. Methods of preparing steviol glycosides and uses of the same
EP2544538B1 (en) 2010-03-12 2022-06-15 PureCircle USA Inc. High-purity steviol glycosides
US20150344512A1 (en) 2011-12-19 2015-12-03 Purecircle Usa Inc. Methods of purifying steviol glycosides and uses of the same
WO2011123236A1 (en) * 2010-04-01 2011-10-06 Biospherics, Inc. D-tagatose and biguanide compositions and methods
CN101926431A (zh) * 2010-08-23 2010-12-29 贵阳高新创嘉创业服务有限公司 一种具有保健功能的组合物及其制备方法和用途
US9578895B2 (en) 2010-08-23 2017-02-28 Epc (Beijing) Natural Products Co., Ltd. Rebaudioside A and stevioside compositions
EP2428123A1 (en) * 2010-09-10 2012-03-14 Nestec S.A. A stevia-based improved sweetening composition and edible products made therewith
JP5859191B2 (ja) 2010-09-29 2016-02-10 松谷化学工業株式会社 高甘味度甘味料に対する呈味改良組成物およびその応用
MX2013004364A (es) 2010-10-19 2013-07-02 Elcelyx Therapeutics Inc Terapias a base de ligando del receptor quimiosensorial.
US9510611B2 (en) 2010-12-13 2016-12-06 Purecircle Sdn Bhd Stevia composition to improve sweetness and flavor profile
BR112013014589B1 (pt) 2010-12-13 2019-04-02 Purecircle Usa Inc. Método para preparar uma composição de rebaudiosídeo d altamente solúvel
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US8796338B2 (en) 2011-01-07 2014-08-05 Elcelyx Therapeutics, Inc Biguanide compositions and methods of treating metabolic disorders
US9211263B2 (en) 2012-01-06 2015-12-15 Elcelyx Therapeutics, Inc. Compositions and methods of treating metabolic disorders
US9572784B2 (en) 2011-01-07 2017-02-21 Elcelyx Therapeutics, Inc. Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk
US9480663B2 (en) 2011-01-07 2016-11-01 Elcelyx Therapeutics, Inc. Biguanide compositions and methods of treating metabolic disorders
EP2661266B1 (en) 2011-01-07 2020-09-16 Anji Pharma (US) LLC Chemosensory receptor ligand-based therapies
MX362676B (es) 2011-02-10 2019-01-31 Purecircle Usa Composición de estevia.
US9474296B2 (en) 2011-02-17 2016-10-25 Purecircle Sdn Bhd Glucosyl stevia composition
US9603373B2 (en) 2011-02-17 2017-03-28 Purecircle Sdn Bhd Glucosyl stevia composition
US11690391B2 (en) 2011-02-17 2023-07-04 Purecircle Sdn Bhd Glucosylated steviol glycoside as a flavor modifier
CN102166274B (zh) * 2011-02-25 2012-05-23 四川大学 从无患子中提取小肠α-葡萄糖苷酶抑制剂的方法
US9795156B2 (en) 2011-03-17 2017-10-24 E.P.C (Beijing) Plant Pharmaceutical Technology Co., Ltd Rebaudioside B and derivatives
US9894922B2 (en) 2011-05-18 2018-02-20 Purecircle Sdn Bhd Glucosyl rebaudioside C
WO2012166163A1 (en) 2011-05-31 2012-12-06 Purecircle Usa Stevia composition
EP3101024A1 (en) 2011-06-03 2016-12-07 Purecircle USA Stevia compostion comprising rebaudioside a or d with rebaudioside b
BR122019003378B1 (pt) 2011-06-20 2020-07-28 Purecircle Usa Inc composição ingerível doce, produto alimentício ou de bebida, preparado de droga, farmacêutico ou cosmético, edulcorante e produto compreendendo a composição ingerível doce
US9771434B2 (en) 2011-06-23 2017-09-26 Purecircle Sdn Bhd Products from stevia rebaudiana
US10480019B2 (en) 2011-08-10 2019-11-19 Purecircle Sdn Bhd Process for producing high-purity rubusoside
EP2753189B1 (en) 2011-09-07 2020-12-16 Purecircle Usa Inc. Highly soluble stevia sweetener
EP3009010B1 (en) 2011-12-19 2020-02-05 PureCircle SDN BHD Methods for purifying steviol glycosides
KR20190120430A (ko) 2012-01-06 2019-10-23 엘셀릭스 테라퓨틱스 인코포레이티드 바이구아나이드 조성물 및 대사 장애를 치료하는 방법
EP2800562A2 (en) 2012-01-06 2014-11-12 Elcelyx Therapeutics, Inc. Compositions and methods for treating metabolic disorders
WO2013108263A1 (en) 2012-01-18 2013-07-25 Zota Health Care Ltd Pharmaceutical formulation to reduce inflammation of bones and joint friction with improved cartilage quality
US8877259B2 (en) 2012-02-09 2014-11-04 Mary Kay Inc. Cosmetic formulation
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
BR112014028819A2 (pt) 2012-05-22 2017-07-25 Purecircle Sdn Bhd glicosídeos de esteviol de pureza elevada
CN102697022B (zh) * 2012-06-19 2014-07-09 天津北方食品有限公司 一种代糖制品及其制备方法
EP2866585B1 (en) * 2012-06-27 2018-06-06 Celanese Sales Germany GmbH Taste-masking compositions, sweetener compositions and consumable product compositions containing the same
US20140272068A1 (en) * 2013-03-14 2014-09-18 Indra Prakash Beverages containing rare sugars
US20140342044A1 (en) 2013-05-14 2014-11-20 Pepsico, Inc. Compositions and Comestibles
US10952458B2 (en) 2013-06-07 2021-03-23 Purecircle Usa Inc Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
CN105682467A (zh) 2013-06-07 2016-06-15 谱赛科美国股份有限公司 含有选择的甜叶菊醇糖苷作为香、咸和甜度特征修饰物的甜叶菊提取物
SG11201510062VA (en) 2013-06-10 2016-01-28 Suntory Holdings Ltd Plant extract containing diketopiperazine and method for producing same
CN103393074A (zh) * 2013-07-24 2013-11-20 兴化格林生物制品有限公司 一种低糖复合甜味剂
US10264811B2 (en) 2014-05-19 2019-04-23 Epc Natural Products Co., Ltd. Stevia sweetener with improved solubility
US10357052B2 (en) 2014-06-16 2019-07-23 Sweet Green Fields USA LLC Rebaudioside A and stevioside with improved solubilities
US10485256B2 (en) 2014-06-20 2019-11-26 Sweet Green Fields International Co., Limited Stevia sweetener with improved solubility with a cyclodextrin
WO2016036578A1 (en) 2014-09-02 2016-03-10 Purecircle Sdn Bhd Stevia extracts
EP3247403A1 (de) * 2015-01-22 2017-11-29 Pfeifer & Langen GmbH & Co. KG Cellobiose in zusammensetzungen zum verzehr oder zur einnahme
WO2017018404A1 (ja) * 2015-07-27 2017-02-02 サントリーホールディングス株式会社 環状ジペプチド及び甘味料を含有する組成物
ES2970118T3 (es) 2015-10-26 2024-05-27 Purecircle Usa Inc Composiciones de glicósido de esteviol
WO2017106577A1 (en) 2015-12-15 2017-06-22 Purecircle Usa Inc. Steviol glycoside compositions
KR101898210B1 (ko) * 2016-07-15 2018-09-12 인그리디언코리아 유한회사 저당함량 감미제 및 이를 포함하는 식품 조성물
US11102995B2 (en) 2016-09-16 2021-08-31 Pepsico, Inc. Compositions and methods for improving taste of non-nutritive sweeteners
US20180133243A1 (en) * 2016-11-16 2018-05-17 Holista Colltech Ltd Method and composition for crude formulations of fortified sugar for glycemic control
CN106727481B (zh) * 2016-12-09 2023-06-20 四川九章生物科技有限公司 绿原酸在制备增强食欲的药物或保健品中的用途
CN106820070B (zh) * 2017-02-20 2020-09-11 湖南艾达伦科技有限公司 一种天然复配甜味剂及其制备方法
US20200229475A1 (en) * 2017-07-27 2020-07-23 Franco Cavaleri Food and beverage sweeteners
US11898184B2 (en) 2017-09-07 2024-02-13 Sweet Sense Inc. Low glycemic sugar composition
CA3078545A1 (en) 2017-10-06 2019-04-11 Cargill, Incorporated Stabilized steviol glycoside compositions and uses thereof
IT201800009539A1 (it) * 2018-10-17 2020-04-17 Hosmer Zambelli Francesca Composizione dolcificante
ES3019388T3 (en) * 2019-04-03 2025-05-20 Firmenich Incorporated Polypodoside sweet flavor modifier
EP3952667A1 (en) 2019-04-06 2022-02-16 Cargill, Incorporated Sensory modifiers
CN110907604A (zh) * 2019-12-06 2020-03-24 浙江华康药业股份有限公司 一种用于改善糖醇类物质感官属性的方法及其应用
IT202000017242A1 (it) * 2020-07-16 2022-01-16 Sinergy Pharma S R L Composizione orale per il mantenimento dei livelli normali di zuccheri nel sangue
GR1010940B (el) * 2024-03-13 2025-05-14 Ιουλια Τσετη Φαρμακευτικη συνθεση μετφορμινης για απο του στοματος χορηγηση
CN120617297B (zh) * 2025-08-13 2025-10-28 济南瑞隆安生物技术有限公司 一种用于i型糖尿病血糖调控的生物制品

Citations (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000045651A1 (en) * 1999-02-02 2000-08-10 Novartis Nutrition Ag Oral arginine and insulin secretion
JP2001211854A (ja) * 2000-01-31 2001-08-07 Saraya Kk 高純度羅漢果配糖体を含有する甘味料組成物
JP2002045145A (ja) * 2000-08-03 2002-02-12 Toyo Seito Kk 甘味料組成物およびその製造方法
JP2002512953A (ja) * 1998-04-29 2002-05-08 住友製薬株式会社 ビグアナイド系薬物の内服製剤
WO2003022208A2 (en) * 2001-09-07 2003-03-20 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
CN1435203A (zh) * 2002-01-30 2003-08-13 王美岭 降糖宁口含片及其生产方法
JP2004505913A (ja) * 2000-08-07 2004-02-26 ランバクシー シグネチャー,エルエルシー メトフォルミンの液体処方
WO2004082664A1 (en) * 2003-03-21 2004-09-30 Ranbaxy Laboratories Limited Water-soluble tablets of metformin
WO2004089343A1 (en) * 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Water soluble tablets
JP2004331576A (ja) * 2003-05-08 2004-11-25 Noevir Co Ltd 急激な血糖値の上昇を抑制する血糖値上昇抑制剤及び食品
US20040253327A1 (en) * 2003-06-12 2004-12-16 Niazi Sarfaraz K. Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides, and sugar and preventing or treating cardiovascular diseases
WO2005000325A2 (en) * 2003-06-30 2005-01-06 Nestec S.A. Composition for treating and/or preventing dysfunctions associated with type 2 diabetes mellitus
US20050016412A1 (en) * 2003-02-10 2005-01-27 Pepperball Technologies, Inc., A Delaware Corporation Stabilized non-lethal projectile systems
US20050019412A1 (en) * 1998-10-01 2005-01-27 Elan Pharma International Limited Novel glipizide compositions
WO2005013957A2 (fr) * 2003-08-06 2005-02-17 Sarl Galenix Innovations Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
WO2005063156A1 (en) * 2003-12-22 2005-07-14 Shear/Kershman Laboratories, Inc. Oral peptide delivery system with improved bioavailability
WO2005072717A1 (ja) * 2004-01-29 2005-08-11 Dainippon Sumitomo Pharma Co., Ltd. ビグアナイド系薬物の内服製剤
WO2005089724A1 (en) * 2004-03-18 2005-09-29 Ardana Bioscience Limited Effervescent formulations comprising desmopressin
WO2005094812A1 (ja) * 2004-04-01 2005-10-13 Ajinomoto Co., Inc. ナテグリニド含有製剤
CN1695602A (zh) * 2005-05-26 2005-11-16 贵阳新天药业股份有限公司 盐酸二甲双胍口服溶液及其制备方法
JP2005320281A (ja) * 2004-05-10 2005-11-17 Shiratori Pharmaceutical Co Ltd インスリン分泌促進剤及び飲食品
US20050276839A1 (en) * 2004-06-10 2005-12-15 Rifkin Calman H Appetite satiation and hydration beverage
WO2006074278A2 (en) * 2005-01-05 2006-07-13 Mitsunori Ono Compositions for treating diabetes or obesity
JP2007518774A (ja) * 2004-01-21 2007-07-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ミトラタピデ経口用溶液

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US723585A (en) * 1902-12-27 1903-03-24 Charlton B Corwin Back-seam trimmer.
US3717477A (en) * 1970-01-16 1973-02-20 Ajinomoto Kk Sweetening agent containing tryptophane and saccharin
US4007288A (en) * 1970-07-16 1977-02-08 General Foods Corporation Low calorie sweetening composition and method for making same
US3725453A (en) * 1970-10-16 1973-04-03 American Home Prod L-4{40 -cyano-3-(2,2,2-trihaloacetamido) succinanilic acids
CH585370A5 (https=) * 1975-04-29 1977-02-28 Von Roll Ag
JPS51142570A (en) * 1975-06-04 1976-12-08 Morita Kagaku Kogyo Method of imparting sweetness to food or pharmaceutical agent
US4256641A (en) * 1976-06-22 1981-03-17 Hoffmann-La Roche Inc. Novel syntheses of tryptophans
US4316847A (en) * 1979-07-30 1982-02-23 Hoffmann-La Roche Inc. Pyrroles and pyrrolidines
US4797298A (en) * 1980-01-21 1989-01-10 Pfizer, Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4894464A (en) * 1980-01-21 1990-01-16 Pfizer Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4804782A (en) * 1980-01-21 1989-02-14 Pfizer, Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4492755A (en) * 1982-06-30 1985-01-08 Nabisco Brands, Inc. Process for isomerizing L-mannose to L-fructose
US4440855A (en) * 1982-06-30 1984-04-03 Nabisco Brands, Inc. Process for preparing L-glucosone
CA1206370A (en) * 1982-08-17 1986-06-24 Ajinomoto Co., Inc. Stabilized aspartame compositions
US4738854A (en) * 1984-12-04 1988-04-19 Nabisco Brands, Inc. Comestible containing moisture and shelf storage stabilized L-aspartic acid derivative
US4638071A (en) * 1984-12-27 1987-01-20 General Foods Corporation Cycloalkyl ethers and thioethers of dipeptides
US4652457A (en) * 1985-05-06 1987-03-24 General Foods Corporation L-aminodicarboxylic acid aminoalkenoic acid ester amides
US4654439A (en) * 1985-05-24 1987-03-31 General Foods Corporation L-aminodicarboxylic acid amides of alkoxyalkylamines
US4814172A (en) * 1985-10-31 1989-03-21 Product Resources International, Inc. Liquid bran drink
US4731246A (en) * 1985-10-31 1988-03-15 Product Resources International, Inc. Liquid bran drink
US4737375A (en) * 1985-12-26 1988-04-12 The Procter & Gamble Company Beverages and beverage concentrates nutritionally supplemented with calcium
US5087460A (en) * 1986-12-10 1992-02-11 Warner-Lambert Company Reduced-calorie confectionery coated chewing gum compositions and methods for preparing same
US5387431A (en) * 1991-10-25 1995-02-07 Fuisz Technologies Ltd. Saccharide-based matrix
US5739409A (en) * 1987-06-19 1998-04-14 The Regents Of The University Of California Endogenously sweetened transgenic plant products
FR2624699B1 (fr) * 1987-12-18 1990-04-13 Bernard Lyon I Universite Clau Derives heterocycliques de n-carbamoyl-, n-thiocarbamoyl- ou n-amidino-glycine ou beta-alanine utiles comme agents edulcorants
JP3084530B2 (ja) * 1989-03-30 2000-09-04 東和化成工業株式会社 脂肪代替物としてのマルチトールを含有する低脂肪食品の製造方法
US5108763A (en) * 1991-04-03 1992-04-28 Warner-Lambert Company Microencapsulated high intensity sweetening agents having prolonged sweetness release and methods for preparing same
US5484593A (en) * 1991-05-28 1996-01-16 Iwasaki; Kazuo Diet composition comprising gymnema inodrum and a method for suppressing the absorption of saccharides
ATE216577T1 (de) * 1992-01-29 2002-05-15 Takeda Chemical Industries Ltd Schnellösliche tablette und ihre herstellung
JPH05316960A (ja) * 1992-05-21 1993-12-03 Takasago Internatl Corp 飲食品の香味を改善する方法
FR2697844B1 (fr) * 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
US5298272A (en) * 1992-12-02 1994-03-29 The Regents Of The University Of California Bridged carboxylic ortho ester sweetener
US5527555A (en) * 1993-02-16 1996-06-18 Wisconsin Alumni Research Foundation Brazzein sweetener
BE1007425A3 (nl) * 1993-08-30 1995-06-13 Holland Sweetener Co Werkwijze en inrichting voor de terugwinning van grondstoffen in het aspartaambereidingsproces.
US5498702A (en) * 1993-12-16 1996-03-12 California Natural Products Treated pectinic acid process and product
EP0751146B1 (en) * 1995-06-30 2002-03-13 Holland Sweetener Company V.o.F. Crystallization of alpha-L-aspartyl-L-phenylalanine methyl ester from aqueous solution
US6822070B2 (en) * 1996-03-11 2004-11-23 David Baltimore Truncated CRAF1 inhibits CD40 signaling
JPH10271928A (ja) * 1997-01-30 1998-10-13 Morita Kagaku Kogyo Kk ステビア・レバウディアナ・ベルトニーに属する新植物
JP3588971B2 (ja) * 1997-05-08 2004-11-17 三菱化学株式会社 低カロリー調製ココア
US6682766B2 (en) * 1997-12-01 2004-01-27 The Procter & Gamble Company Beverage comprising an effective amount of flavanols as sweetness cutting composition
US6168811B1 (en) * 1998-06-18 2001-01-02 Kellogg Company Fortified edible compositions and process of making
JP4221078B2 (ja) * 1998-07-09 2009-02-12 株式会社林原生物化学研究所 トレハロース2含水結晶とその製造方法並びに用途
US6214402B1 (en) * 1998-09-17 2001-04-10 The Nutrasweet Company Co-crystallization of sugar and n-[n-(3,3-dimethylbutyl)-l αaspartyl]-l-phenylalanine 1-methyl ester
PT1139793E (pt) * 1998-12-23 2010-01-19 Sinai School Medicine Inibidores da resposta ao sabor amargo
US6048999A (en) * 1999-01-25 2000-04-11 The Nutrasweet Company N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester synergistic sweetener blends
US6180157B1 (en) * 1999-02-18 2001-01-30 The Nutrasweet Company Process for preparing an N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester agglomerate
US6365216B1 (en) * 1999-03-26 2002-04-02 The Nutrasweet Company Particles of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester
WO2000069283A1 (en) * 1999-05-13 2000-11-23 The Nutrasweet Company USE OF ADDITIVES TO MODIFY THE TASTE CHARACTERISTICS OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER
AU7627800A (en) * 1999-08-06 2001-03-05 Nutrasweet Company, The Process for coating n-[n-(3,3-dimethylbutyl)-l-alpha-aspartyl]-l-phenylalanine 1-methyl ester onto a carrier
US20050042271A1 (en) * 1999-11-19 2005-02-24 Xel Herbaceuticals, Inc . Transdermal delivery system for alkaloids of aconitum species
WO2001056959A1 (en) * 2000-02-01 2001-08-09 Stevia Aps A substance for the use in a dietary supplementation or for the preparation of a medicament for the treatment of non-insulin dependent diabetes mellitus, hypertension and/or the metabolic syndrome
EP1125507A1 (en) * 2000-02-15 2001-08-22 Tiense Suikerraffinaderij N.V. (Raffinerie Tirlemontoise S.A.) Inulin products with improved nutritional properties
WO2001060842A2 (en) * 2000-02-16 2001-08-23 The Nutrasweet Company PROCESS FOR MAKING GRANULATED N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
US20020150662A1 (en) * 2000-04-19 2002-10-17 Dewis Mark Lawrence Ethyl 3-mercaptobutyrate as a flavoring or fragrance agent and methods for preparing and using same
US6534107B1 (en) * 2000-05-12 2003-03-18 The Coca-Cola Company Quality fruit juice beverages having extended quality shelf-life and methods of making the same
AU3955002A (en) * 2000-11-17 2002-06-03 Mcneil Ppc Inc Meltable form of sucralose
WO2002080704A1 (en) * 2001-04-03 2002-10-17 Michigan Biotechnology Institute Composition for improving the taste and sweetness profile of beverages having intense sweeteners
DK1377280T3 (da) * 2001-04-09 2007-10-08 Danisco Usa Inc Fyldmidler som mæthedsfornemmelsesgivende midler
US7815956B2 (en) * 2001-04-27 2010-10-19 Pepsico Use of erythritol and D-tagatose in diet or reduced-calorie beverages and food products
US20020192350A1 (en) * 2001-04-30 2002-12-19 Hynes Michael P. Food products
US20030049352A1 (en) * 2001-05-31 2003-03-13 Haile Mehansho Fortified drinking water
DE10130504B4 (de) * 2001-06-25 2005-02-03 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Xanthin- und Phenazon-Acesulfam-H-Komplexe mit verbessertem Geschmack, Verfahren zu ihrer Herstellung und ihre Verwendung
US20030021874A1 (en) * 2001-07-02 2003-01-30 The Procter & Gamble Co. Stabilized compositions and processes of their preparation
JP3378577B1 (ja) * 2001-09-28 2003-02-17 花王株式会社 飲 料
AU2002349604A1 (en) * 2001-11-30 2003-06-10 Ajinomoto Co., Inc. Crystals of non-natural stereoisomer salts of monatin and utilization thereof
US6998480B2 (en) * 2002-03-08 2006-02-14 Tate & Lyle Public Limited Company Process for improving sucralose purity and yield
US20040170735A2 (en) * 2002-04-05 2004-09-02 Mcneil-Ppc, Inc. Methods and compositions for altering the sweetness delivery profile of sucralose
AU2003237987A1 (en) * 2002-06-07 2003-12-22 Ann De Wees Allen Novel sweetener compositions and methods of use
US20040058050A1 (en) * 2002-09-25 2004-03-25 Peilin Guo Herbal sweetening composition
AU2003298659A1 (en) * 2002-11-15 2004-06-15 Cargill, Incorporated Soluble isoflavone compositions
AU2003901230A0 (en) * 2003-03-18 2003-04-03 Wharton, Geoffrey Mr New generation of electrical plugs and socket systems
US6984732B2 (en) * 2003-03-31 2006-01-10 Mcneil-Ppc, Inc. High-intensity sweetener composition and delivery of same
US7390518B2 (en) * 2003-07-11 2008-06-24 Cadbury Adams Usa, Llc Stain removing chewing gum composition
JPWO2005027656A1 (ja) * 2003-09-22 2007-11-15 株式会社ユース・テクノコーポレーション 機能性甘味料
DE10348723A1 (de) * 2003-10-16 2005-05-12 Nutrinova Gmbh Süßstoffkombination zur Süßung von Obstkonserven
ES2235642B2 (es) * 2003-12-18 2006-03-01 Gat Formulation Gmbh Proceso de multi-microencapsulacion continuo para la mejora de la estabilidad y almacenamiento de ingredientes biologicamente activos.
US20050146255A1 (en) * 2004-01-06 2005-07-07 Irving Sabo Outdoor storage container having hinged and removable lids
JP2005200330A (ja) * 2004-01-14 2005-07-28 Meiji Seika Kaisha Ltd 血糖改善剤
US20060013842A1 (en) * 2004-07-15 2006-01-19 Matkin John R Natural mixture of long-chain fatty alcohols and long-chain fatty acids, its obtension from animal and vegetable waxes and its nutraceutical uses
US20060024245A1 (en) * 2004-07-29 2006-02-02 Cadbury Adams, Llc. Tooth whitening compositions and delivery systems therefor
US7641892B2 (en) * 2004-07-29 2010-01-05 Cadburry Adams USA, LLC Tooth whitening compositions and delivery systems therefor
US8101208B2 (en) * 2004-08-11 2012-01-24 Kraft Foods Global Brands Llc Sensate compositions and delivery systems therefor
WO2006018318A1 (en) * 2004-08-18 2006-02-23 Synthon B.V. Liquid paroxetine compositions
CA2578258C (en) * 2004-08-25 2012-11-13 Cadbury Adams Usa Llc Liquid-filled chewing gum composition
US7641926B2 (en) * 2004-08-25 2010-01-05 Cadbury Adams Usa, Llc Liquid-filled chewing gum composition
US20060062872A1 (en) * 2004-09-23 2006-03-23 Cadbury Adams Usa Llc Pressurized chewing gum compositions and dispensing method
US7910755B2 (en) * 2004-09-29 2011-03-22 Harbor Biosciences, Inc. Stem cell expansion and uses
JP4344334B2 (ja) * 2005-03-04 2009-10-14 佐藤製薬株式会社 ステビア由来甘味物質を含有する甘味料
CN101198319B (zh) * 2005-04-26 2012-08-01 大日本住友制药株式会社 含有双胍化合物的颗粒制剂
JP2006314240A (ja) * 2005-05-12 2006-11-24 Meiji Seika Kaisha Ltd 血糖値上昇抑制低カロリー甘味料
WO2006133349A2 (en) * 2005-06-08 2006-12-14 Alpharma, Inc. Orally disintegrable sleep aid formulations
WO2007006320A1 (en) * 2005-07-12 2007-01-18 Sherine Hassan Abbas Helmy Drinkable oral insulin liquid and capsules
CN101242807B (zh) * 2005-08-12 2014-12-10 洲际大品牌有限责任公司 口腔润湿组合物,包含该组合物的递送系统及其制造方法
US20070082105A1 (en) * 2005-09-13 2007-04-12 Robbins Gregory C Polysaccharide sweetener compounds, process for manufacture, and method of selecting components for polysaccharide sweetener compounds based on user specific sweetener applications
WO2007044526A2 (en) * 2005-10-05 2007-04-19 Cadbury Adams Usa Llc Menthyl ester containing cooling compositions
US7807206B2 (en) * 2005-10-11 2010-10-05 Purecircle Sdn Bhd Sweetner and use
US7862845B2 (en) * 2005-10-11 2011-01-04 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof

Patent Citations (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002512953A (ja) * 1998-04-29 2002-05-08 住友製薬株式会社 ビグアナイド系薬物の内服製剤
US20050019412A1 (en) * 1998-10-01 2005-01-27 Elan Pharma International Limited Novel glipizide compositions
WO2000045651A1 (en) * 1999-02-02 2000-08-10 Novartis Nutrition Ag Oral arginine and insulin secretion
JP2001211854A (ja) * 2000-01-31 2001-08-07 Saraya Kk 高純度羅漢果配糖体を含有する甘味料組成物
JP2002045145A (ja) * 2000-08-03 2002-02-12 Toyo Seito Kk 甘味料組成物およびその製造方法
JP2004505913A (ja) * 2000-08-07 2004-02-26 ランバクシー シグネチャー,エルエルシー メトフォルミンの液体処方
WO2003022208A2 (en) * 2001-09-07 2003-03-20 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
CN1435203A (zh) * 2002-01-30 2003-08-13 王美岭 降糖宁口含片及其生产方法
US20050016412A1 (en) * 2003-02-10 2005-01-27 Pepperball Technologies, Inc., A Delaware Corporation Stabilized non-lethal projectile systems
WO2004082664A1 (en) * 2003-03-21 2004-09-30 Ranbaxy Laboratories Limited Water-soluble tablets of metformin
WO2004089343A1 (en) * 2003-04-09 2004-10-21 Ranbaxy Laboratories Limited Water soluble tablets
JP2004331576A (ja) * 2003-05-08 2004-11-25 Noevir Co Ltd 急激な血糖値の上昇を抑制する血糖値上昇抑制剤及び食品
US20040253327A1 (en) * 2003-06-12 2004-12-16 Niazi Sarfaraz K. Compositions and methods for reducing or controlling blood cholesterol, lipoproteins, triglycerides, and sugar and preventing or treating cardiovascular diseases
WO2005000325A2 (en) * 2003-06-30 2005-01-06 Nestec S.A. Composition for treating and/or preventing dysfunctions associated with type 2 diabetes mellitus
WO2005013957A2 (fr) * 2003-08-06 2005-02-17 Sarl Galenix Innovations Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation
WO2005063156A1 (en) * 2003-12-22 2005-07-14 Shear/Kershman Laboratories, Inc. Oral peptide delivery system with improved bioavailability
JP2007518774A (ja) * 2004-01-21 2007-07-12 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ミトラタピデ経口用溶液
WO2005072717A1 (ja) * 2004-01-29 2005-08-11 Dainippon Sumitomo Pharma Co., Ltd. ビグアナイド系薬物の内服製剤
WO2005089724A1 (en) * 2004-03-18 2005-09-29 Ardana Bioscience Limited Effervescent formulations comprising desmopressin
WO2005094812A1 (ja) * 2004-04-01 2005-10-13 Ajinomoto Co., Inc. ナテグリニド含有製剤
JP2005320281A (ja) * 2004-05-10 2005-11-17 Shiratori Pharmaceutical Co Ltd インスリン分泌促進剤及び飲食品
US20050276839A1 (en) * 2004-06-10 2005-12-15 Rifkin Calman H Appetite satiation and hydration beverage
WO2006074278A2 (en) * 2005-01-05 2006-07-13 Mitsunori Ono Compositions for treating diabetes or obesity
CN1695602A (zh) * 2005-05-26 2005-11-16 贵阳新天药业股份有限公司 盐酸二甲双胍口服溶液及其制备方法

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011182684A (ja) * 2010-03-05 2011-09-22 Ito En Ltd カルシウム含有無果汁炭酸飲料
JP2014506460A (ja) * 2011-01-25 2014-03-17 モネル ケミカル センシズ センター 甘味を提供若しくは調整するための組成物および方法ならびにそれらのスクリーニング方法
JP2016136974A (ja) * 2011-01-25 2016-08-04 モネル ケミカル センシズ センターMonell Chemical Senses Center 甘味を提供若しくは調整するための組成物および方法ならびにそれらのスクリーニング方法
JP2016163580A (ja) * 2011-01-28 2016-09-08 テート アンド ライル イングリーディエンツ アメリカズ エルエルシー レバウディオサイドbを含有するステビアブレンド
JP2019058179A (ja) * 2011-01-28 2019-04-18 テート アンド ライル イングリーディエンツ アメリカズ エルエルシー レバウディオサイドbを含有するステビアブレンド
US10583314B2 (en) 2011-01-28 2020-03-10 Tate & Lyle Ingredients Americas Llc Stevia blends containing rebaudioside B
US11801402B2 (en) 2011-01-28 2023-10-31 Tate & Lyle Solutions Usa Llc Stevia blends containing rebaudioside b
JP2014529994A (ja) * 2011-09-15 2014-11-17 シージェイ チェイルジェダング コーポレイション 遅消化性成分を含有する糖尿改善用甘味素材組成物
JP2016127836A (ja) * 2011-09-15 2016-07-14 シージェイ チェイルジェダング コーポレイション 遅消化性成分を含有する糖尿改善用甘味素材組成物
JP2013116056A (ja) * 2011-12-01 2013-06-13 Healthy Sweet:Kk チョコレート
JP2014093981A (ja) * 2012-11-09 2014-05-22 Mc Food Specialties Inc 飲食品の甘味の味質改善方法

Also Published As

Publication number Publication date
WO2008057968A2 (en) 2008-05-15
WO2008057968A3 (en) 2008-09-12
US20080107787A1 (en) 2008-05-08
AU2007317372A1 (en) 2008-05-15
EP2091356A2 (en) 2009-08-26
JP2014139224A (ja) 2014-07-31
CN101568266A (zh) 2009-10-28

Similar Documents

Publication Publication Date Title
JP2010509232A (ja) 高甘味度甘味料を含む抗糖尿病組成物
EP1959755B1 (en) High-potency sweetener composition with c-reactive protein reducing substance and compositions sweetened therewith
JP5330380B2 (ja) 甘味増強剤、甘味が増強された甘味料組成物、これらの配合方法および使用方法
EP1959762B1 (en) High-potency sweetener composition for treatment and/or prevention of autoimmune disorders, compositions and beverages sweetened therewith
EP1962616B1 (en) High-potency sweetener composition with glucosamine and compositions sweetened therewith
KR101379494B1 (ko) 시간 특성 및/또는 향미 특성이 개선된 천연의 고효능 식탁용 감미료 조성물, 이들의 제제 방법 및 용도
EP2160103B1 (en) Sweetener compositions having enhanced sweetness and improved temporal and/or flavor profiles
TWI402040B (zh) 含維生素之高效能甜味劑組成物及經其增甜之組成物
US20070116829A1 (en) Pharmaceutical Composition with High-Potency Sweetener
JP2010508821A (ja) フィトエストロゲンを有する高甘味度甘味料組成物及びこれにより甘味を付与された組成物
JP2009517044A (ja) 抗炎症剤を含む高甘味度甘味料組成物及びこれにより甘味を付与された組成物
JP2009523407A (ja) 酸化防止剤を含む高甘味度甘味料組成物及びこれにより甘味を付与された組成物
JP2010508822A (ja) ルビスコタンパク、ルビスコリン、ルビスコリン誘導体、ace抑制ペプチド、及びこれらの組合せを有する高甘味度甘味料組成物、及びこれにより甘味を付与された組成物
JP2009517025A (ja) 水分補給用高甘味度甘味料及び甘味料入り水分補給組成物
JP2010508823A (ja) 長鎖第一級脂肪族飽和アルコールを有する高甘味度甘味料組成物及びこれにより甘味を付与された組成物
JP2009517036A (ja) サポニンを含む高甘味度甘味料組成物及びこれにより甘味を付与された組成物
JP2009517038A (ja) 体重管理用高甘味度甘味料組成物及びこれにより甘味を付与された組成物
CN101340827A (zh) 供水合作用用之高效甜味剂及甜化水合组成物
JP2009517033A (ja) 骨粗鬆症を治療及び/又は予防する高甘味度甘味料組成物及びこれにより甘味を付与された組成物
JP2009517031A (ja) 高効能甘味料を用いた糖菓

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20101027

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20101027

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130220

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130513

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130520

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130820

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131128