JP2010508286A5 - - Google Patents
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- Publication number
- JP2010508286A5 JP2010508286A5 JP2009534842A JP2009534842A JP2010508286A5 JP 2010508286 A5 JP2010508286 A5 JP 2010508286A5 JP 2009534842 A JP2009534842 A JP 2009534842A JP 2009534842 A JP2009534842 A JP 2009534842A JP 2010508286 A5 JP2010508286 A5 JP 2010508286A5
- Authority
- JP
- Japan
- Prior art keywords
- ester
- sucrose
- tio
- solid
- solid superacid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 29
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims 24
- 239000007787 solid Substances 0.000 claims 19
- 239000003930 superacid Substances 0.000 claims 19
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims 14
- 229910010413 TiO 2 Inorganic materials 0.000 claims 14
- 239000003054 catalyst Substances 0.000 claims 13
- 239000003960 organic solvent Substances 0.000 claims 10
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims 7
- 150000002148 esters Chemical class 0.000 claims 7
- 239000004376 Sucralose Substances 0.000 claims 6
- 235000019408 sucralose Nutrition 0.000 claims 6
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 5
- 229930006000 Sucrose Natural products 0.000 claims 5
- BAQAVOSOZGMPRM-QBMZZYIRSA-N sucralose Chemical compound O[C@@H]1[C@@H](O)[C@@H](Cl)[C@@H](CO)O[C@@H]1O[C@@]1(CCl)[C@@H](O)[C@H](O)[C@@H](CCl)O1 BAQAVOSOZGMPRM-QBMZZYIRSA-N 0.000 claims 5
- 239000005720 sucrose Substances 0.000 claims 5
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 3
- 239000012320 chlorinating reagent Substances 0.000 claims 3
- DCKVFVYPWDKYDN-UHFFFAOYSA-L oxygen(2-);titanium(4+);sulfate Chemical compound [O-2].[Ti+4].[O-]S([O-])(=O)=O DCKVFVYPWDKYDN-UHFFFAOYSA-L 0.000 claims 3
- 239000011541 reaction mixture Substances 0.000 claims 3
- 229910052719 titanium Inorganic materials 0.000 claims 3
- 239000010936 titanium Substances 0.000 claims 3
- 229910000348 titanium sulfate Inorganic materials 0.000 claims 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical group [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims 2
- 238000007664 blowing Methods 0.000 claims 2
- 238000001354 calcination Methods 0.000 claims 2
- 238000005660 chlorination reaction Methods 0.000 claims 2
- 230000032050 esterification Effects 0.000 claims 2
- 238000005886 esterification reaction Methods 0.000 claims 2
- 230000002194 synthesizing effect Effects 0.000 claims 2
- VZGDMQKNWNREIO-UHFFFAOYSA-N tetrachloromethane Chemical compound ClC(Cl)(Cl)Cl VZGDMQKNWNREIO-UHFFFAOYSA-N 0.000 claims 2
- SCYULBFZEHDVBN-UHFFFAOYSA-N 1,1-Dichloroethane Chemical compound CC(Cl)Cl SCYULBFZEHDVBN-UHFFFAOYSA-N 0.000 claims 1
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 claims 1
- GSNUFIFRDBKVIE-UHFFFAOYSA-N DMF Natural products CC1=CC=C(C)O1 GSNUFIFRDBKVIE-UHFFFAOYSA-N 0.000 claims 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 claims 1
- QQVDYSUDFZZPSU-UHFFFAOYSA-M chloromethylidene(dimethyl)azanium;chloride Chemical compound [Cl-].C[N+](C)=CCl QQVDYSUDFZZPSU-UHFFFAOYSA-M 0.000 claims 1
- 239000000706 filtrate Substances 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- -1 sucralose ester Chemical class 0.000 claims 1
- 239000011701 zinc Substances 0.000 claims 1
- 229910052725 zinc Inorganic materials 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/552,813 US20080103295A1 (en) | 2006-10-25 | 2006-10-25 | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
| PCT/US2007/082424 WO2008052077A2 (en) | 2006-10-25 | 2007-10-24 | Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010508286A JP2010508286A (ja) | 2010-03-18 |
| JP2010508286A5 true JP2010508286A5 (enExample) | 2011-01-20 |
Family
ID=39325403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009534842A Pending JP2010508286A (ja) | 2006-10-25 | 2007-10-24 | 固体の超酸触媒の存在下におけるエステル化によるスクロース−６−エステルの製造方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080103295A1 (enExample) |
| EP (1) | EP2097432A4 (enExample) |
| JP (1) | JP2010508286A (enExample) |
| KR (1) | KR20090082421A (enExample) |
| CN (1) | CN101558076A (enExample) |
| AU (1) | AU2007308948A1 (enExample) |
| BR (1) | BRPI0718058A2 (enExample) |
| CA (1) | CA2667366A1 (enExample) |
| MX (1) | MX2009004356A (enExample) |
| RU (1) | RU2009119517A (enExample) |
| TW (1) | TW200833707A (enExample) |
| WO (1) | WO2008052077A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8258291B2 (en) * | 2006-10-25 | 2012-09-04 | Mamtek International Limited | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC) |
| US8149122B2 (en) * | 2008-03-05 | 2012-04-03 | Metropolitan Industries, Inc. | Liquid level detection system with floating RFID tag |
| US20100022765A1 (en) * | 2008-07-23 | 2010-01-28 | David Losan Ho | Methods for extracting and purifying sucralose intermediate |
| US7862744B2 (en) * | 2008-07-23 | 2011-01-04 | Mamtek International Limited | Methods and systems for preparing materials for sucralose production |
| EP2643338B1 (en) | 2010-11-23 | 2016-04-06 | Lexington Pharmaceuticals Laboratories, LLC | Low temperature chlorination of carbohydrates |
| MX342969B (es) | 2011-10-14 | 2016-10-20 | Lexington Pharmaceuticals Laboratories Llc | Cloracion de carbohidratos y derivados de carbohidratos. |
| CN106622302A (zh) * | 2016-11-29 | 2017-05-10 | 华东理工大学 | 一种制备高纯度烯烃的催化剂的制备方法 |
| CN112973166B (zh) * | 2019-12-17 | 2024-04-30 | 无锡弘鼎华化工设备有限公司 | 一种三氯蔗糖中和液溶剂的回收装置及方法 |
| CN111205340B (zh) * | 2020-02-18 | 2021-06-29 | 万华化学集团股份有限公司 | 一种蔗糖-6-乙酸酯的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3072725A (en) * | 1960-11-14 | 1963-01-08 | Du Pont | Preparation of dimethylformamide |
| EP0043649B1 (en) * | 1980-07-08 | 1984-09-12 | TATE & LYLE PUBLIC LIMITED COMPANY | Process for the preparation of 4, 1',6'-trichloro-4,1',6'-trideoxygalactosucrose (tgs) |
| GB8818430D0 (en) * | 1988-08-03 | 1988-09-07 | Tate & Lyle Plc | Process |
| US4980463A (en) * | 1989-07-18 | 1990-12-25 | Noramco, Inc. | Sucrose-6-ester chlorination |
| CO4410191A1 (es) * | 1994-09-19 | 1997-01-09 | Lilly Co Eli | SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS |
| US5498709A (en) * | 1994-10-17 | 1996-03-12 | Mcneil-Ppc, Inc. | Production of sucralose without intermediate isolation of crystalline sucralose-6-ester |
| US6998480B2 (en) * | 2002-03-08 | 2006-02-14 | Tate & Lyle Public Limited Company | Process for improving sucralose purity and yield |
| CN1176094C (zh) * | 2003-05-23 | 2004-11-17 | 广东省食品工业研究所 | 一种三氯蔗糖的合成方法 |
| US20060205936A1 (en) * | 2005-03-14 | 2006-09-14 | Sl Laboratories, Llc | Chlorination of Sucrose-6-esters |
| US8258291B2 (en) * | 2006-10-25 | 2012-09-04 | Mamtek International Limited | Process for the preparation of sucralose by the chlorination of sugar with triphosgene (BTC) |
-
2006
- 2006-10-25 US US11/552,813 patent/US20080103295A1/en not_active Abandoned
-
2007
- 2007-10-19 TW TW096139366A patent/TW200833707A/zh unknown
- 2007-10-24 CN CNA2007800436663A patent/CN101558076A/zh active Pending
- 2007-10-24 BR BRPI0718058-6A2A patent/BRPI0718058A2/pt not_active IP Right Cessation
- 2007-10-24 WO PCT/US2007/082424 patent/WO2008052077A2/en not_active Ceased
- 2007-10-24 RU RU2009119517/04A patent/RU2009119517A/ru not_active Application Discontinuation
- 2007-10-24 JP JP2009534842A patent/JP2010508286A/ja active Pending
- 2007-10-24 KR KR1020097010473A patent/KR20090082421A/ko not_active Withdrawn
- 2007-10-24 MX MX2009004356A patent/MX2009004356A/es not_active Application Discontinuation
- 2007-10-24 EP EP07854399A patent/EP2097432A4/en not_active Withdrawn
- 2007-10-24 AU AU2007308948A patent/AU2007308948A1/en not_active Abandoned
- 2007-10-24 CA CA002667366A patent/CA2667366A1/en not_active Abandoned
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