JP2010504993A - 薬物を含むフィルム−製品を投与する方法 - Google Patents

薬物を含むフィルム−製品を投与する方法 Download PDF

Info

Publication number
JP2010504993A
JP2010504993A JP2009530551A JP2009530551A JP2010504993A JP 2010504993 A JP2010504993 A JP 2010504993A JP 2009530551 A JP2009530551 A JP 2009530551A JP 2009530551 A JP2009530551 A JP 2009530551A JP 2010504993 A JP2010504993 A JP 2010504993A
Authority
JP
Japan
Prior art keywords
film
product
polyethylene oxide
drug
polymer composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009530551A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010504993A5 (https=
Inventor
ギャリー エル マイヤーズ
リチャード シー フイズ
Original Assignee
モノソル アールエックス リミテッド ライアビリティ カンパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by モノソル アールエックス リミテッド ライアビリティ カンパニー filed Critical モノソル アールエックス リミテッド ライアビリティ カンパニー
Publication of JP2010504993A publication Critical patent/JP2010504993A/ja
Publication of JP2010504993A5 publication Critical patent/JP2010504993A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2009530551A 2006-09-26 2007-09-25 薬物を含むフィルム−製品を投与する方法 Pending JP2010504993A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/526,996 US20080050422A1 (en) 2001-10-12 2006-09-26 Method of administering a film product containing a drug
PCT/US2007/079357 WO2008039737A2 (en) 2006-09-26 2007-09-25 A method of administering a film product containing a drug

Publications (2)

Publication Number Publication Date
JP2010504993A true JP2010504993A (ja) 2010-02-18
JP2010504993A5 JP2010504993A5 (https=) 2010-11-11

Family

ID=39166452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009530551A Pending JP2010504993A (ja) 2006-09-26 2007-09-25 薬物を含むフィルム−製品を投与する方法

Country Status (7)

Country Link
US (1) US20080050422A1 (https=)
EP (1) EP2079457A2 (https=)
JP (1) JP2010504993A (https=)
CN (1) CN101534803A (https=)
AU (1) AU2007300197A1 (https=)
CA (1) CA2664669A1 (https=)
WO (1) WO2008039737A2 (https=)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008169138A (ja) * 2007-01-11 2008-07-24 Tsukioka:Kk フィルム状製剤及びフィルム状製剤の製造方法
JP2011207875A (ja) * 2010-03-11 2011-10-20 Teika Seiyaku Kk フィルム状製剤
JP2012532133A (ja) * 2009-06-30 2012-12-13 ダウ グローバル テクノロジーズ エルエルシー 日焼け防止剤含有可溶性フィルム
JP2014518550A (ja) * 2011-04-12 2014-07-31 モノソル・アールエックス・エルエルシー 二重レーンコーティング
JP2015514775A (ja) * 2012-04-18 2015-05-21 マリンクロッド エルエルシー 即放性乱用抑止医薬組成物
JP2018197216A (ja) * 2017-05-24 2018-12-13 株式会社プラスアルファー フィルムシート状栄養剤
JP2018203618A (ja) * 2017-05-30 2018-12-27 日清ファルマ株式会社 コエンザイムｑ１０フィルム製剤
JP2023522320A (ja) * 2020-04-15 2023-05-30 エルテーエス ローマン テラピー－ジステーメ アーゲー 滑らかな融合フィルムを有する口腔内フィルム製剤

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100753959B1 (ko) * 2006-01-12 2007-08-31 에이펫(주) 기판 건조장치를 이용한 기판 건조방법
US8323695B2 (en) 2007-08-13 2012-12-04 Mcneil-Ppc, Inc. Method for stabilizing phenylephrine
US8623401B2 (en) * 2008-03-27 2014-01-07 Fenwafe Inc. Wafer formulation
US20110159058A1 (en) * 2008-08-25 2011-06-30 Kyukyu Pharmaceutical Co., Ltd. Film preparation containing loperamide hydrochloride
PT2952191T (pt) 2009-06-12 2018-11-30 Sunovion Pharmaceuticals Inc Apomorfina sublingual
DK3254676T3 (en) 2009-10-30 2019-03-11 Ix Biopharma Ltd QUICK-SOLVING SOLID DOSAGE FORM
US12186426B2 (en) 2009-10-30 2025-01-07 Ix Biopharma Ltd. Solid dosage form
CN102048711B (zh) * 2009-11-11 2013-06-05 河北奥星集团药业有限公司 一种格拉司琼膜制剂及其制备方法
CA2784587A1 (en) 2009-12-28 2011-07-28 Monosol Rx, Llc Orally administrable film dosage forms containing ondansetron
US20120308635A1 (en) * 2009-12-30 2012-12-06 Novartis Ag Melt extruded thin strips containing coated pharmaceutical
CN102440979A (zh) * 2010-09-30 2012-05-09 迪特克(济源)绿色生物科技有限公司 一种纤维素衍生物复合膜及其制备方法
NZ612686A (en) 2010-12-16 2015-11-27 Cynapsus Therapeutics Inc Sublingual films
PT3164117T (pt) 2014-07-03 2023-12-12 SpecGx LLC Formulações de libertação imediata de dissuasão de abuso compreendendo polissacáridos não celulósicos
US20160220480A1 (en) * 2015-02-03 2016-08-04 Intelgenx Corp. Oral dosage film exhibiting enhanced mucosal penetration
JP7211706B2 (ja) 2015-04-21 2023-01-24 サノヴィオン ファーマシュティカルズ インコーポレーテッド 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法
DE102018101778A1 (de) * 2018-01-26 2019-08-01 Lts Lohmann Therapie-Systeme Ag Mehrschichtiger Oraler Dünnfilm
US11648197B2 (en) * 2018-06-28 2023-05-16 Arx, Llc Dispensing method for producing dissolvable unit dose film constructs
US20210267934A1 (en) * 2018-07-15 2021-09-02 Rapid Dose Therapeutics Corp. Cannabinoid oral dispersible film strip
WO2020068510A1 (en) 2018-09-25 2020-04-02 SpecGx LLC Abuse deterrent immediate release capsule dosage forms
EP3895691A1 (en) * 2020-04-15 2021-10-20 LTS Lohmann Therapie-Systeme AG Ulipristal acetate otf

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03500164A (ja) * 1987-04-20 1991-01-17 フュイズ・ファーマシューティカル・リミテッド 迅速に溶解する繊維状医薬組成物およびその製造方法
JP2003213038A (ja) * 2001-11-16 2003-07-30 Natl Starch & Chem Investment Holding Corp デンプンを含有するフィルム
JP2006503003A (ja) * 2002-07-26 2006-01-26 ファイザー・インク 経口摂取できる剤形を作製する方法
WO2006031209A1 (en) * 2003-05-28 2006-03-23 Monosolrx Llc Polyethylene oxide-based films and drug delivery systems made therefrom
WO2006039264A1 (en) * 2004-09-30 2006-04-13 Monosolrx, Llc Multi-layer films having uniform content

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU679937B2 (en) * 1992-11-18 1997-07-17 Johnson & Johnson Consumer Products, Inc. Extrudable compositions for topical or transdermal drug delivery
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
ATE398465T1 (de) * 2001-11-16 2008-07-15 Givaudan Sa Essbare folie
EP1504765B1 (en) * 2002-05-16 2015-07-22 Kyukyu Pharmaceutical Co., Ltd. Quickly soluble film preparations

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03500164A (ja) * 1987-04-20 1991-01-17 フュイズ・ファーマシューティカル・リミテッド 迅速に溶解する繊維状医薬組成物およびその製造方法
JP2003213038A (ja) * 2001-11-16 2003-07-30 Natl Starch & Chem Investment Holding Corp デンプンを含有するフィルム
JP2006503003A (ja) * 2002-07-26 2006-01-26 ファイザー・インク 経口摂取できる剤形を作製する方法
WO2006031209A1 (en) * 2003-05-28 2006-03-23 Monosolrx Llc Polyethylene oxide-based films and drug delivery systems made therefrom
WO2006039264A1 (en) * 2004-09-30 2006-04-13 Monosolrx, Llc Multi-layer films having uniform content

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008169138A (ja) * 2007-01-11 2008-07-24 Tsukioka:Kk フィルム状製剤及びフィルム状製剤の製造方法
JP2012532133A (ja) * 2009-06-30 2012-12-13 ダウ グローバル テクノロジーズ エルエルシー 日焼け防止剤含有可溶性フィルム
JP2011207875A (ja) * 2010-03-11 2011-10-20 Teika Seiyaku Kk フィルム状製剤
JP2014518550A (ja) * 2011-04-12 2014-07-31 モノソル・アールエックス・エルエルシー 二重レーンコーティング
US11129799B2 (en) 2011-04-12 2021-09-28 Aquestive Therapeutics, Inc. Dual lane coating
JP2015514775A (ja) * 2012-04-18 2015-05-21 マリンクロッド エルエルシー 即放性乱用抑止医薬組成物
JP2018197216A (ja) * 2017-05-24 2018-12-13 株式会社プラスアルファー フィルムシート状栄養剤
JP2018203618A (ja) * 2017-05-30 2018-12-27 日清ファルマ株式会社 コエンザイムｑ１０フィルム製剤
JP2023522320A (ja) * 2020-04-15 2023-05-30 エルテーエス ローマン テラピー－ジステーメ アーゲー 滑らかな融合フィルムを有する口腔内フィルム製剤
JP7833405B2 (ja) 2020-04-15 2026-03-19 エルテーエス ローマン テラピー－ジステーメ アーゲー 滑らかな融合フィルムを有する口腔内フィルム製剤

Also Published As

Publication number Publication date
AU2007300197A1 (en) 2008-04-03
CN101534803A (zh) 2009-09-16
US20080050422A1 (en) 2008-02-28
WO2008039737A3 (en) 2008-05-22
EP2079457A2 (en) 2009-07-22
CA2664669A1 (en) 2008-04-03
WO2008039737A2 (en) 2008-04-03

Similar Documents

Publication Publication Date Title
JP4739452B2 (ja) 発泡を減じる風味付与剤を含む喫食可能な水溶性フィルム
JP2010504993A (ja) 薬物を含むフィルム−製品を投与する方法
JP5538905B2 (ja) ポリマーを主成分とするフィルムおよびこれから製造した薬物放出系
JP6109865B2 (ja) 非自己凝集性で均一な混成を示す薄いフィルム、およびそれから作製した薬物送達システム
JP6035369B2 (ja) 自己凝集しない均一な異種性を有する薄膜、その生成方法、およびそれから製造した薬物送達系
CN1812773B (zh) 基于聚氧乙烯的薄膜及由其制造的药物传递系统
JP5144776B2 (ja) 味マスキング組成物を含む迅速溶解剤形用の均一フィルム
JP2010509905A6 (ja) 発泡を減じる風味付与剤を含む喫食可能な水溶性フィルム
JP5719778B2 (ja) 可食性フィルムの製造方法
JP2010515761A (ja) 高用量フィルム組成物およびその製法
JP2009507854A (ja) 粘着防止剤を組み込む即溶性製剤用の均一なフィルム
CN105229401B (zh) 通过控制干燥失重使湿薄膜干燥的方法
WO2008147772A1 (en) Film shreds and delivery systems incorporating same
JP2009518405A (ja) 活性物質の送達のための局所フィルム組成物
US20070154527A1 (en) Topical film compositions for delivery of actives
JP2009521532A (ja) 活性物質を放出するための、ｐＨ調節されたフィルム
CA2906050C (en) Films and drug delivery systems for rizatriptan

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100924

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100924

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20121011

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121022

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20121214

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130118

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130125

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130222

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130301

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20130624