JP2010504972A5 - - Google Patents
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- Publication number
- JP2010504972A5 JP2010504972A5 JP2009530404A JP2009530404A JP2010504972A5 JP 2010504972 A5 JP2010504972 A5 JP 2010504972A5 JP 2009530404 A JP2009530404 A JP 2009530404A JP 2009530404 A JP2009530404 A JP 2009530404A JP 2010504972 A5 JP2010504972 A5 JP 2010504972A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- self
- acid domain
- assembling peptide
- biologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001413 amino acids Chemical class 0.000 claims 13
- 108090000765 processed proteins & peptides Proteins 0.000 claims 4
- 230000000295 complement effect Effects 0.000 claims 2
- 230000002209 hydrophobic effect Effects 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 125000005647 linker group Chemical group 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84730306P | 2006-09-26 | 2006-09-26 | |
| US60/847,303 | 2006-09-26 | ||
| PCT/US2007/020754 WO2008039483A2 (en) | 2006-09-26 | 2007-09-26 | Modified self-assembling peptides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013229859A Division JP2014062102A (ja) | 2006-09-26 | 2013-11-05 | 修飾自己組織化ペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010504972A JP2010504972A (ja) | 2010-02-18 |
| JP2010504972A5 true JP2010504972A5 (enExample) | 2010-11-11 |
| JP5496671B2 JP5496671B2 (ja) | 2014-05-21 |
Family
ID=39230811
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009530404A Expired - Fee Related JP5496671B2 (ja) | 2006-09-26 | 2007-09-26 | 修飾自己組織化ペプチド |
| JP2013229859A Pending JP2014062102A (ja) | 2006-09-26 | 2013-11-05 | 修飾自己組織化ペプチド |
| JP2015158226A Expired - Fee Related JP6224040B2 (ja) | 2006-09-26 | 2015-08-10 | 修飾自己組織化ペプチド |
| JP2017129570A Expired - Fee Related JP6430595B2 (ja) | 2006-09-26 | 2017-06-30 | 修飾自己組織化ペプチド |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013229859A Pending JP2014062102A (ja) | 2006-09-26 | 2013-11-05 | 修飾自己組織化ペプチド |
| JP2015158226A Expired - Fee Related JP6224040B2 (ja) | 2006-09-26 | 2015-08-10 | 修飾自己組織化ペプチド |
| JP2017129570A Expired - Fee Related JP6430595B2 (ja) | 2006-09-26 | 2017-06-30 | 修飾自己組織化ペプチド |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8022178B2 (enExample) |
| EP (2) | EP2860194B1 (enExample) |
| JP (4) | JP5496671B2 (enExample) |
| ES (1) | ES2709125T3 (enExample) |
| WO (1) | WO2008039483A2 (enExample) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9327010B2 (en) | 2005-04-25 | 2016-05-03 | Massachusetts Institute Of Technology | Compositions and methods for promoting hemostasis and other physiological activities |
| CN101472620A (zh) | 2006-04-25 | 2009-07-01 | 麻省理工学院 | 用于影响污染物、机体流体或其它实体移动和/或影响其它生理状况的组合物和方法 |
| US20090112215A1 (en) | 2007-10-29 | 2009-04-30 | Sherman Jason T | Opto-electric indicators for orthopaedic instruments |
| EP2345433B1 (en) * | 2008-10-06 | 2017-03-01 | 3-D Matrix, Ltd. | Tissue plug |
| CN102348717B (zh) † | 2009-03-09 | 2015-11-25 | 株式会社美你康 | 自组装肽和高强度肽凝胶 |
| JP2011012042A (ja) * | 2009-07-03 | 2011-01-20 | Three D Matrix:Kk | 核酸徐放担体 |
| US20110117195A1 (en) * | 2009-11-18 | 2011-05-19 | National Cheng Kung University | Method for improving myocardial infarction by intramyocardial or transendocardial injection of peptide nanofibers |
| US9439941B2 (en) | 2009-12-14 | 2016-09-13 | The University Of Hong Kong | Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells |
| WO2011132018A1 (en) | 2010-04-19 | 2011-10-27 | Universita' Degli Studi Di Milano Bicocca | Novel self-assembling peptides and their use in the formation of hydrogels |
| US8741833B2 (en) | 2010-07-16 | 2014-06-03 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| WO2012008967A1 (en) * | 2010-07-16 | 2012-01-19 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| WO2012027218A2 (en) | 2010-08-27 | 2012-03-01 | Corning Incorporated | Peptide-modified surfaces for cell culture |
| US20130281602A1 (en) * | 2010-10-08 | 2013-10-24 | Solvay Sa | Thermo-responsive polymer covalently bound with a peptide |
| JP2012082180A (ja) * | 2010-10-14 | 2012-04-26 | Nagoya Univ | 骨再生用自己組織化ペプチドハイドロゲル |
| JP6084352B2 (ja) * | 2010-12-24 | 2017-02-22 | 国立大学法人 岡山大学 | 高強度ペプチドゲル |
| WO2012162637A2 (en) | 2011-05-26 | 2012-11-29 | Kansas State University Research Foundation | Vaccine adjuvants from self-assembling peptides |
| GB2496654A (en) | 2011-11-18 | 2013-05-22 | Reckitt & Colman Overseas | Self-assembling peptides |
| EP2607373A1 (en) * | 2011-12-23 | 2013-06-26 | Solvay Sa | Liquid phase synthesis of self-assembling peptides to be linked to polymers or to other bioactive and/or self-assembling peptides |
| CN103288929A (zh) * | 2012-03-01 | 2013-09-11 | 上海中医药大学 | 一种促进移植干细胞存活和分化的纳米生物材料 |
| KR101348096B1 (ko) | 2012-03-29 | 2014-01-09 | 한국과학기술연구원 | 줄기세포의 연골 분화 유도 활성을 가지는 폴리펩타이드 |
| CN102952176A (zh) * | 2012-05-22 | 2013-03-06 | 西北工业大学 | 具有促成骨生长的生物活性多肽及其制备方法 |
| JP6389170B2 (ja) | 2012-07-06 | 2018-09-12 | スリーディー マトリックス, エルティーディー3−D Matrix, Ltd. | ペプチド溶液のためのフィル−フィニッシュ過程 |
| ES2933048T3 (es) * | 2012-08-17 | 2023-01-31 | Amsilk Gmbh | Uso de polipéptidos de autoensamblaje como adhesivos tisulares |
| WO2014056199A1 (zh) * | 2012-10-12 | 2014-04-17 | 清华大学 | 多肽的产生和纯化方法 |
| US9642695B2 (en) | 2012-10-26 | 2017-05-09 | Jms Co., Ltd. | Artificial blood vessel, and method for producing artificial blood vessel |
| US9241891B2 (en) | 2012-10-30 | 2016-01-26 | The Procter & Gamble Company | Personal care compositions comprising self-assembling peptides |
| CA2886109A1 (en) * | 2012-12-07 | 2014-06-12 | Kansas State University Research Foundation | Peptide-albumin hydrogel properties and its applications |
| KR20160003651A (ko) * | 2013-03-14 | 2016-01-11 | 가부시끼가이샤 쓰리디 매트릭스 | 위장 폐색 예방용 물질 |
| EP2968135A4 (en) * | 2013-03-14 | 2016-10-26 | Massachusetts Inst Technology | INJECTABLE, MULTILAYER, SELF-COMPOSITE PEPTIDE RUBBER HYDROGELS FOR LONG-TERM AND DELAYED RELEASE OF HUMAN ANTIBODIES |
| US9526762B1 (en) | 2013-08-09 | 2016-12-27 | William Marsh Rice University | Multidomain peptides for promoting angiogenesis |
| WO2015022883A1 (ja) | 2013-08-14 | 2015-02-19 | 独立行政法人理化学研究所 | 光透過性に優れた生物材料を調製するための組成物およびその利用 |
| CN105658252A (zh) * | 2013-08-22 | 2016-06-08 | 阿奇生物外科有限公司 | 用于控制流体移动的可植入网状物 |
| ES2712608T3 (es) | 2014-03-10 | 2019-05-14 | 3 D Matrix Ltd | Péptidos autoensamblantes para el tratamiento de las bullas pulmonares |
| CA2939696C (en) | 2014-03-10 | 2023-01-10 | 3-D Matrix, Ltd. | Self-assembling peptide compositions |
| JP6684719B2 (ja) | 2014-03-10 | 2020-04-22 | 株式会社スリー・ディー・マトリックス | ペプチド組成物の滅菌および濾過 |
| KR101595063B1 (ko) * | 2014-04-24 | 2016-02-18 | 단국대학교 천안캠퍼스 산학협력단 | 세포결합 서열, 헤파린 결합 도메인 및 오스테오칼신 도메인을 포함하는 융합단백질 및 이를 포함하는 약학 조성물 |
| WO2015194194A1 (en) * | 2014-06-20 | 2015-12-23 | 3-D Matrix, Ltd. | Materials and methods for filling bone voids |
| US10821136B2 (en) | 2014-06-30 | 2020-11-03 | National University Corporation Tokai National Higher Education And Research System | Bone formation promoter |
| WO2016004216A2 (en) * | 2014-07-01 | 2016-01-07 | Vicus Therapeutics, Llc | Hydrogels for treating and ameliorating infections and methods of making and using them |
| US10201338B1 (en) | 2014-09-10 | 2019-02-12 | Abyrx, Inc. | Device for the application of surgical materials to tissue |
| KR101678740B1 (ko) * | 2014-10-24 | 2016-11-23 | 단국대학교 천안캠퍼스 산학협력단 | 세포 부착활성 및 골분화 촉진활성을 나타내는 피브로넥틴 융합단백질 |
| PT3219330T (pt) * | 2014-11-14 | 2020-01-17 | 3 D Matrix Ltd | Síntese de nano agregado de quitosano modificado por péptido de auto-montagem e sua aplicação na aplicação de proteína |
| DE102015000363A1 (de) | 2015-01-20 | 2016-07-21 | Emc Microcollections Gmbh | Neue modular funktionalisierbare Peptid-Hydrogele |
| JP6886402B2 (ja) | 2015-08-24 | 2021-06-16 | 株式会社スリー・ディー・マトリックス | 生分解性インジェクタブルゲル |
| US10800822B2 (en) | 2015-11-30 | 2020-10-13 | The Board Of Trustees Of The University Of Illinois | Histatins and method of use thereof |
| WO2017120092A1 (en) | 2016-01-06 | 2017-07-13 | 3-D Matrix, Ltd. | Combination compositions |
| CN105669870B (zh) * | 2016-03-16 | 2020-01-10 | 重庆医科大学附属第一医院 | 自组装多肽d-RADA16-RGD及其制备方法和应用 |
| US11246924B2 (en) | 2016-04-01 | 2022-02-15 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
| EP3463495A1 (en) * | 2016-06-01 | 2019-04-10 | 3-D Matrix Ltd. | Hemostatic dressings with self-assembling peptide hydrogels |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| US11185568B2 (en) * | 2017-04-14 | 2021-11-30 | President And Fellows Of Harvard College | Methods for generation of cell-derived microfilament network |
| US20220387605A1 (en) * | 2017-07-18 | 2022-12-08 | Duke University | Compositions and methods comprising self-assembling peptide-polymer nanofibers for sublingual immunization |
| EP3723726A1 (en) | 2017-12-15 | 2020-10-21 | 3-D Matrix, Ltd. | Surfactant peptide nanostructures and uses in drug delivery |
| WO2020171161A1 (ja) * | 2019-02-20 | 2020-08-27 | 国立大学法人東京農工大学 | 自己組織化ペプチド |
| CN110256572B (zh) * | 2019-05-07 | 2022-11-01 | 西北大学 | 一种rhc-(rada)4融合蛋白 |
| US20220088275A1 (en) * | 2019-05-20 | 2022-03-24 | Convalesce Inc. | Hydrogels, methods of making, and methods of use |
| CN110201184A (zh) * | 2019-05-28 | 2019-09-06 | 南方医科大学珠江医院 | 双靶向配体的心脑微血管药物及其制备方法 |
| EP3952973B1 (en) | 2019-06-13 | 2023-06-07 | Hollister Incorporated | Reusable urinary catheter products |
| AU2020304005B2 (en) | 2019-06-25 | 2025-12-04 | Hollister Incorporated | Reusable urinary catheter products |
| WO2021062374A1 (en) | 2019-09-27 | 2021-04-01 | Duke University | Tabletization of peptide self-assemblies and methods of making and using the same |
| US20210106506A1 (en) * | 2019-10-11 | 2021-04-15 | Elc Management Llc | Methods for cosmetic skin remodeling |
| JP7537678B2 (ja) * | 2020-03-16 | 2024-08-21 | 国立大学法人 東京医科歯科大学 | 自己組織化ペプチドを含む組成物 |
| US20230203116A1 (en) * | 2020-07-30 | 2023-06-29 | National University Corporation Tokyo Medical And Dental University | Self-assembling peptide |
| JP2024506048A (ja) * | 2021-02-10 | 2024-02-08 | 株式会社スリー・ディー・マトリックス | 特異的な自己組織化ペプチドrada16を含む、炎症性腸疾患などの下部消化管疾患を治療又は予防するための医薬組成物 |
| JP2024507871A (ja) * | 2021-02-23 | 2024-02-21 | ノースウェスタン ユニバーシティ | 動力学的生理活性足場及びcns損傷後のその治療的使用 |
| CN113512094B (zh) * | 2021-06-29 | 2023-04-14 | 兰州大学 | 一种共价光交联多肽、共价光交联多肽自组装形成的胶原蛋白仿生材料 |
| CN114230640A (zh) * | 2021-12-21 | 2022-03-25 | 西安交通大学 | 一种具有自组装能力的氨基酸缩合物 |
| CN116715730A (zh) * | 2023-04-27 | 2023-09-08 | 暨南大学 | 一种自组装小分子肽及其在抗血管生成中的应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4315074A (en) * | 1978-05-19 | 1982-02-09 | Pierce Chemical Company | Molecular transformation procedure |
| GB8427651D0 (en) * | 1984-11-01 | 1984-12-05 | Beecham Group Plc | Compounds |
| US5109113A (en) * | 1986-05-02 | 1992-04-28 | Genentech, Inc. | Membrane anchor fusion polypeptides |
| IL85372A (en) | 1987-02-12 | 1992-12-01 | Us Health | Penta to nona-peptides with laminin - like activity having an amino acid sequence and anti- metastatic compositions containing them |
| US5843156A (en) | 1988-08-24 | 1998-12-01 | Endoluminal Therapeutics, Inc. | Local polymeric gel cellular therapy |
| ES2054365T3 (es) * | 1989-06-30 | 1994-08-01 | Massachusetts Inst Technology | Inhibicion de la via de la regla del n final en celulas vivas. |
| US5670483A (en) | 1992-12-28 | 1997-09-23 | Massachusetts Insititute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5955343A (en) | 1992-12-28 | 1999-09-21 | Massachusetts Institute Of Technology | Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor |
| US5763212A (en) * | 1994-02-04 | 1998-06-09 | California Institute Of Technology | Inhibiting degradation of a degron-bearing protein |
| US6673604B1 (en) | 1999-07-23 | 2004-01-06 | Diacrin, Inc. | Muscle cells and their use in cardiac repair |
| JP2001161813A (ja) * | 1999-12-09 | 2001-06-19 | Nissho Corp | 医療用チューブ |
| JP2003520050A (ja) | 2000-01-24 | 2003-07-02 | フィロス インク. | タンパク質分析のための高感度多重化診断アッセイ法 |
| US6884778B2 (en) * | 2000-04-14 | 2005-04-26 | William Marsh Rice University | Biocompatible macromers |
| ATE419333T1 (de) * | 2001-02-06 | 2009-01-15 | Massachusetts Inst Technology | Peptidgerüstverkapselung von gewebszellen und verwendungen davon |
| US7449180B2 (en) | 2001-02-06 | 2008-11-11 | John Kisiday | Macroscopic scaffold containing amphiphilic peptides encapsulating cells |
| WO2003096972A2 (en) | 2002-05-13 | 2003-11-27 | Massachusetts Institute Of Technology | Angiogenesis and cardiac tissue engineering with peptide hydrogels and related compositions and methods of use thereof |
| CA2387257C (en) | 2002-05-23 | 2009-07-28 | Suncor Energy Inc. | Static deaeration conditioner for processing of bitumen froth |
| JP4419448B2 (ja) * | 2003-06-17 | 2010-02-24 | 株式会社ジェイ・エム・エス | 医療用チューブ |
| US7713923B2 (en) | 2003-06-25 | 2010-05-11 | Massachusetts Institute Of Technology | Self-assembling peptides incorporating modifications and methods of use thereof |
| DK1636250T3 (en) * | 2003-06-25 | 2016-02-22 | Massachusetts Inst Technology | SELF-ORGANIZING PEPTIDES, CONTAINING MODIFICATIONS, AND APPLICATIONS THEREOF |
| US7884185B2 (en) * | 2004-07-28 | 2011-02-08 | University Of Delaware | Hydrogels and uses thereof |
| US7429567B2 (en) | 2005-01-04 | 2008-09-30 | The Brigham And Women's Hospital, Inc. | Sustained delivery of PDGF using self-assembling peptide nanofibers |
| US9327010B2 (en) | 2005-04-25 | 2016-05-03 | Massachusetts Institute Of Technology | Compositions and methods for promoting hemostasis and other physiological activities |
-
2007
- 2007-09-26 US US11/904,278 patent/US8022178B2/en not_active Expired - Fee Related
- 2007-09-26 EP EP14185394.5A patent/EP2860194B1/en not_active Not-in-force
- 2007-09-26 EP EP07861376A patent/EP2066697A2/en not_active Withdrawn
- 2007-09-26 ES ES14185394T patent/ES2709125T3/es active Active
- 2007-09-26 JP JP2009530404A patent/JP5496671B2/ja not_active Expired - Fee Related
- 2007-09-26 WO PCT/US2007/020754 patent/WO2008039483A2/en not_active Ceased
-
2013
- 2013-11-05 JP JP2013229859A patent/JP2014062102A/ja active Pending
-
2015
- 2015-08-10 JP JP2015158226A patent/JP6224040B2/ja not_active Expired - Fee Related
-
2017
- 2017-06-30 JP JP2017129570A patent/JP6430595B2/ja not_active Expired - Fee Related
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