JP2010504285A5 - - Google Patents

Info

Publication number

JP2010504285A5

JP2010504285A5 JP2009526743A JP2009526743A JP2010504285A5 JP 2010504285 A5 JP2010504285 A5 JP 2010504285A5 JP 2009526743 A JP2009526743 A JP 2009526743A JP 2009526743 A JP2009526743 A JP 2009526743A JP 2010504285 A5 JP2010504285 A5 JP 2010504285A5

Authority

JP

Japan

Prior art keywords

substituted

group

independently represents

residue

following formula

Prior art date

2007-08-31

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Abandoned

Links

• Espacenet
• Global Dossier
• Discuss

• -1 amine compound Chemical class 0.000 claims 17
• 239000008194 pharmaceutical composition Substances 0.000 claims 16
• 125000003118 aryl group Chemical group 0.000 claims 8
• 125000000217 alkyl group Chemical group 0.000 claims 6
• 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 6
• 239000000203 mixture Substances 0.000 claims 6
• 150000001412 amines Chemical class 0.000 claims 5
• 229920000642 polymer Polymers 0.000 claims 5
• SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 claims 4
• 125000002723 alicyclic group Chemical group 0.000 claims 4
• PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 claims 4
• SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 claims 4
• 150000001875 compounds Chemical class 0.000 claims 4
• 239000003431 cross linking reagent Substances 0.000 claims 4
• 125000000623 heterocyclic group Chemical group 0.000 claims 4
• 201000005991 hyperphosphatemia Diseases 0.000 claims 4
• JCQKQWAONVEFJC-UHFFFAOYSA-N 3-hydroxy-2,2-bis(hydroxymethyl)propanal Chemical compound OCC(CO)(CO)C=O JCQKQWAONVEFJC-UHFFFAOYSA-N 0.000 claims 2
• YTBSYETUWUMLBZ-UHFFFAOYSA-N D-Erythrose Natural products OCC(O)C(O)C=O YTBSYETUWUMLBZ-UHFFFAOYSA-N 0.000 claims 2
• WQZGKKKJIJFFOK-CBPJZXOFSA-N D-Gulose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O WQZGKKKJIJFFOK-CBPJZXOFSA-N 0.000 claims 2
• WQZGKKKJIJFFOK-WHZQZERISA-N D-aldose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-WHZQZERISA-N 0.000 claims 2
• WQZGKKKJIJFFOK-IVMDWMLBSA-N D-allopyranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@H](O)[C@@H]1O WQZGKKKJIJFFOK-IVMDWMLBSA-N 0.000 claims 2
• YTBSYETUWUMLBZ-IUYQGCFVSA-N D-erythrose Chemical compound OC[C@@H](O)[C@@H](O)C=O YTBSYETUWUMLBZ-IUYQGCFVSA-N 0.000 claims 2
• WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 claims 2
• HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims 2
• YTBSYETUWUMLBZ-QWWZWVQMSA-N D-threose Chemical compound OC[C@@H](O)[C@H](O)C=O YTBSYETUWUMLBZ-QWWZWVQMSA-N 0.000 claims 2
• 206010056474 Erythrosis Diseases 0.000 claims 2
• WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims 2
• LKDRXBCSQODPBY-AMVSKUEXSA-N L-(-)-Sorbose Chemical compound OCC1(O)OC[C@H](O)[C@@H](O)[C@@H]1O LKDRXBCSQODPBY-AMVSKUEXSA-N 0.000 claims 2
• WQZGKKKJIJFFOK-VSOAQEOCSA-N L-altropyranose Chemical compound OC[C@@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-VSOAQEOCSA-N 0.000 claims 2
• PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims 2
• HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims 2
• WQZGKKKJIJFFOK-PHYPRBDBSA-N alpha-D-galactose Chemical compound OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-PHYPRBDBSA-N 0.000 claims 2
• SRBFZHDQGSBBOR-STGXQOJASA-N alpha-D-lyxopyranose Chemical compound O[C@@H]1CO[C@H](O)[C@@H](O)[C@H]1O SRBFZHDQGSBBOR-STGXQOJASA-N 0.000 claims 2
• PYMYPHUHKUWMLA-WDCZJNDASA-N arabinose Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)C=O PYMYPHUHKUWMLA-WDCZJNDASA-N 0.000 claims 2
• WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims 2
• 229930182830 galactose Natural products 0.000 claims 2
• 239000008103 glucose Substances 0.000 claims 2
• 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
• 125000002951 idosyl group Chemical class C1([C@@H](O)[C@H](O)[C@@H](O)[C@H](O1)CO)* 0.000 claims 2
• 150000005846 sugar alcohols Chemical class 0.000 claims 2
• 239000000412 dendrimer Substances 0.000 claims 1
• 229920000736 dendritic polymer Polymers 0.000 claims 1
• 150000002825 nitriles Chemical group 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 125000001424 substituent group Chemical group 0.000 claims 1
• DFMPWLMMFFGNKY-QFSHWATDSA-N C=CCN(CCCN)CCCOCC(COCCCN(CCCN)CCCN)(COCCCN(CCCN)CCCN)COCCCN(CCCN)/C=C/CN Chemical compound C=CCN(CCCN)CCCOCC(COCCCN(CCCN)CCCN)(COCCCN(CCCN)CCCN)COCCCN(CCCN)/C=C/CN DFMPWLMMFFGNKY-QFSHWATDSA-N 0.000 description 1
• GDOPTJXRTPNYNR-UHFFFAOYSA-N CC1CCCC1 Chemical compound CC1CCCC1 GDOPTJXRTPNYNR-UHFFFAOYSA-N 0.000 description 1