JP2010195828A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2010195828A5 JP2010195828A5 JP2010126865A JP2010126865A JP2010195828A5 JP 2010195828 A5 JP2010195828 A5 JP 2010195828A5 JP 2010126865 A JP2010126865 A JP 2010126865A JP 2010126865 A JP2010126865 A JP 2010126865A JP 2010195828 A5 JP2010195828 A5 JP 2010195828A5
- Authority
- JP
- Japan
- Prior art keywords
- solvate
- showing
- viii
- formula
- diphenylacetamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012453 solvate Substances 0.000 claims 5
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 3
- HXGBXQDTNZMWGS-RUZDIDTESA-N darifenacin Chemical compound C=1C=CC=CC=1C([C@H]1CN(CCC=2C=C3CCOC3=CC=2)CC1)(C(=O)N)C1=CC=CC=C1 HXGBXQDTNZMWGS-RUZDIDTESA-N 0.000 claims 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims 1
- 238000010521 absorption reaction Methods 0.000 claims 1
- 238000005102 attenuated total reflection Methods 0.000 claims 1
- 229910052802 copper Inorganic materials 0.000 claims 1
- 239000010949 copper Substances 0.000 claims 1
- 229960002677 darifenacin Drugs 0.000 claims 1
- 238000002329 infrared spectrum Methods 0.000 claims 1
- 239000003456 ion exchange resin Substances 0.000 claims 1
- 229920003303 ion-exchange polymer Polymers 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000000634 powder X-ray diffraction Methods 0.000 claims 1
- 230000005855 radiation Effects 0.000 claims 1
- 238000000646 scanning calorimetry Methods 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0207104.1A GB0207104D0 (en) | 2002-03-26 | 2002-03-26 | Stable hydrate of a muscarinic receptor antagonist |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003578353A Division JP2005524678A (ja) | 2002-03-26 | 2003-03-17 | ムスカリン性レセプターアンタゴニストの安定水和物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010195828A JP2010195828A (ja) | 2010-09-09 |
| JP2010195828A5 true JP2010195828A5 (enExample) | 2011-07-28 |
Family
ID=9933731
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003578353A Withdrawn JP2005524678A (ja) | 2002-03-26 | 2003-03-17 | ムスカリン性レセプターアンタゴニストの安定水和物 |
| JP2010126865A Pending JP2010195828A (ja) | 2002-03-26 | 2010-06-02 | ムスカリン性レセプターアンタゴニストの安定水和物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003578353A Withdrawn JP2005524678A (ja) | 2002-03-26 | 2003-03-17 | ムスカリン性レセプターアンタゴニストの安定水和物 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6930188B2 (enExample) |
| EP (2) | EP2336124B1 (enExample) |
| JP (2) | JP2005524678A (enExample) |
| KR (4) | KR101026283B1 (enExample) |
| CN (1) | CN100345840C (enExample) |
| AR (1) | AR042608A1 (enExample) |
| AT (1) | ATE495169T1 (enExample) |
| AU (1) | AU2003209921A1 (enExample) |
| BR (2) | BRPI0308706B8 (enExample) |
| CA (1) | CA2480287C (enExample) |
| CY (2) | CY1111200T1 (enExample) |
| DE (1) | DE60335711D1 (enExample) |
| DK (2) | DK2336124T3 (enExample) |
| ES (2) | ES2358644T3 (enExample) |
| GB (1) | GB0207104D0 (enExample) |
| PA (1) | PA8569701A1 (enExample) |
| PT (2) | PT1490357E (enExample) |
| SI (2) | SI2336124T1 (enExample) |
| SV (1) | SV2003001515A (enExample) |
| TW (1) | TW200306816A (enExample) |
| UY (1) | UY27735A1 (enExample) |
| WO (1) | WO2003080599A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0207104D0 (en) * | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
| US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
| JP2008538784A (ja) * | 2005-04-24 | 2008-11-06 | ワイス | 膀胱機能を調節するための方法 |
| WO2007076159A2 (en) * | 2005-12-27 | 2007-07-05 | Teva Pharmaceutical Industries Ltd. | Pure darifenacin hydrobromide substantially free of oxidized darifenacin and salts thereof and processes for the preparation thereof |
| EP2109601A2 (en) * | 2007-01-05 | 2009-10-21 | Dr. Reddy's Laboratories Ltd. | Preparation of darifenacin and its salts |
| KR101495708B1 (ko) * | 2007-02-23 | 2015-02-25 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | 무스카린 수용체 안타고니스트로 유용한 4차 암모늄 디페닐메틸 화합물 |
| WO2008144602A1 (en) * | 2007-05-18 | 2008-11-27 | Auspex Pharmaceuticals, Inc. | Deuterated zamifenacin derivatives |
| US20100204296A1 (en) * | 2007-06-08 | 2010-08-12 | Actavis Group Ptc Ehf | Novel Polymorphs of Darifenacin Free Base and its Hydrobromide Salt |
| WO2009006413A1 (en) * | 2007-06-30 | 2009-01-08 | Auspex Pharmaceuticals, Inc. | Substituted pyrrolidines |
| US20090018346A1 (en) * | 2007-07-13 | 2009-01-15 | Medichem, S.A. | Amorphous Form Of Darifenacin Hydrobromide And Processes For The Preparation Thereof |
| CZ300895B6 (cs) * | 2008-01-28 | 2009-09-02 | Zentiva, A. S. | Zpusob prípravy Darifenacinu |
| WO2009125426A2 (en) * | 2008-02-08 | 2009-10-15 | Neuland Laboratories Ltd | NOVEL PROCESS FOR THE PREPARATION OF (3SM-[2-(2 J-DIHYDRO-5- BENZOFURANYLϊETHYL]-α.α -DIPHENYL-3-PYRROLIDINEACETAMIDE HYDROBROMIDE |
| JP5450387B2 (ja) | 2008-04-02 | 2014-03-26 | 株式会社カネカ | （ｓ）−３−（１−シアノ−１，１−ジフェニルメチル）−ピロリジンの製造法 |
| US20110144354A1 (en) * | 2008-09-22 | 2011-06-16 | Watson Pharma Private Limited | Process for Preparation of Darifenacin and Intermediates Used in the Process |
| EP2236509A1 (en) | 2009-04-01 | 2010-10-06 | Ragactives, S.L. | Method for obtaining 1,3-difunctionalized pyrrolidine derivatives |
| WO2011070419A1 (en) | 2009-12-10 | 2011-06-16 | Aurobindo Pharma Limited | An improved process for the preparation of darifenacin hydrobromide |
| US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2017106175A2 (en) * | 2015-12-14 | 2017-06-22 | Ironwood Pharmaceuticals, Inc. | USE OF sGC STIMULATORS FOR THE TREATMENT OF GASTROINTESTINAL SPHINCTER DYSFUNCTION |
| WO2018029140A1 (de) * | 2016-08-12 | 2018-02-15 | Bayer Cropscience Aktiengesellschaft | Verfahren zur herstellung von substituierten styrol-derivaten |
| WO2019053051A1 (en) * | 2017-09-12 | 2019-03-21 | Lts Lohmann Therapie-Systeme Ag | MICRO NEEDLE IONTOPHORESIS DEVICE |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5233053A (en) * | 1989-03-17 | 1993-08-03 | Pfizer Inc. | Pyrrolidine derivatives |
| GB8906166D0 (en) * | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| GB9400600D0 (en) * | 1994-01-14 | 1994-03-09 | Pfizer Ltd | Treatment of motion seckness |
| GB9518953D0 (en) * | 1995-09-15 | 1995-11-15 | Pfizer Ltd | Pharmaceutical formulations |
| GB9612710D0 (en) * | 1996-06-18 | 1996-08-21 | Pfizer Ltd | Method of treatment |
| KR20010029519A (ko) * | 1996-09-19 | 2001-04-06 | 이곤 이 버그 | 요실금 치료 방법 |
| GB9711643D0 (en) | 1997-06-05 | 1997-07-30 | Janssen Pharmaceutica Nv | Glass thermoplastic systems |
| GB0207104D0 (en) * | 2002-03-26 | 2002-05-08 | Pfizer Ltd | Stable hydrate of a muscarinic receptor antagonist |
-
2002
- 2002-03-26 GB GBGB0207104.1A patent/GB0207104D0/en not_active Ceased
-
2003
- 2003-03-17 KR KR1020047015243A patent/KR101026283B1/ko not_active Expired - Lifetime
- 2003-03-17 EP EP10177716A patent/EP2336124B1/en not_active Expired - Lifetime
- 2003-03-17 ES ES03744716T patent/ES2358644T3/es not_active Expired - Lifetime
- 2003-03-17 JP JP2003578353A patent/JP2005524678A/ja not_active Withdrawn
- 2003-03-17 AU AU2003209921A patent/AU2003209921A1/en not_active Abandoned
- 2003-03-17 CN CNB038070847A patent/CN100345840C/zh not_active Expired - Lifetime
- 2003-03-17 WO PCT/IB2003/001043 patent/WO2003080599A1/en not_active Ceased
- 2003-03-17 EP EP03744716A patent/EP1490357B1/en not_active Expired - Lifetime
- 2003-03-17 AT AT03744716T patent/ATE495169T1/de active
- 2003-03-17 PT PT03744716T patent/PT1490357E/pt unknown
- 2003-03-17 BR BRPI0308706A patent/BRPI0308706B8/pt not_active IP Right Cessation
- 2003-03-17 DK DK10177716.7T patent/DK2336124T3/da active
- 2003-03-17 PT PT101777167T patent/PT2336124E/pt unknown
- 2003-03-17 DK DK03744716.6T patent/DK1490357T3/da active
- 2003-03-17 DE DE60335711T patent/DE60335711D1/de not_active Expired - Lifetime
- 2003-03-17 KR KR1020107018853A patent/KR20100101182A/ko not_active Ceased
- 2003-03-17 CA CA2480287A patent/CA2480287C/en not_active Expired - Lifetime
- 2003-03-17 SI SI200332215T patent/SI2336124T1/sl unknown
- 2003-03-17 KR KR1020117027931A patent/KR101212908B1/ko not_active Expired - Lifetime
- 2003-03-17 KR KR1020127018787A patent/KR20120098888A/ko not_active Ceased
- 2003-03-17 BR BR122018000397A patent/BR122018000397B8/pt not_active IP Right Cessation
- 2003-03-17 ES ES10177716T patent/ES2394067T3/es not_active Expired - Lifetime
- 2003-03-17 SI SI200331973T patent/SI1490357T1/sl unknown
- 2003-03-20 PA PA20038569701A patent/PA8569701A1/es unknown
- 2003-03-24 AR ARP030101017A patent/AR042608A1/es unknown
- 2003-03-25 US US10/396,887 patent/US6930188B2/en not_active Expired - Lifetime
- 2003-03-25 UY UY27735A patent/UY27735A1/es not_active Application Discontinuation
- 2003-03-25 TW TW092106635A patent/TW200306816A/zh unknown
- 2003-03-25 SV SV2003001515A patent/SV2003001515A/es not_active Application Discontinuation
-
2005
- 2005-07-13 US US11/180,433 patent/US20050245597A1/en not_active Abandoned
-
2008
- 2008-03-17 US US12/049,660 patent/US7696357B2/en not_active Expired - Lifetime
-
2010
- 2010-06-02 JP JP2010126865A patent/JP2010195828A/ja active Pending
-
2011
- 2011-02-22 CY CY20111100213T patent/CY1111200T1/el unknown
-
2012
- 2012-11-29 CY CY20121101165T patent/CY1113433T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2010195828A5 (enExample) | ||
| RU2599785C3 (ru) | Кристаллические формы 5-хлор-n2-(2-изопропокси-5-метил-4-пиперидин-4-ил-фенил)-n4-[2-(пропан-2-сульфонил)-фенил]-пиримидин-2,4-диамина | |
| JP2014524442A5 (enExample) | ||
| FI2534153T4 (fi) | 8-fluori-2-{4-[(metyyliamino}metyyli]fenyyli}-1,3,4,5-tetrahydro-6h-atsepino[5,4,3-cd]indol-6-onin suoloja ja polymorfeja | |
| JP2013509429A5 (enExample) | ||
| JP2011518833A5 (enExample) | ||
| JP2014502599A5 (enExample) | ||
| JP2009254428A5 (enExample) | ||
| JP2015522037A5 (enExample) | ||
| RU2017134709A (ru) | П-толуолсульфонат для ингибитора мек-киназы и его кристаллическая форма, и способ его получения | |
| JP2015516425A5 (enExample) | ||
| JP2022037040A5 (enExample) | ||
| JP2015506987A5 (enExample) | ||
| JP2021517111A5 (enExample) | ||
| ME02102B (me) | Novi polimorf | |
| HRP20220031T1 (hr) | Kristalni trihidratni oblik (3s,3s') 4,4'-disulfanedilbis (3-aminobutan 1-sulfonske kiseline) | |
| RU2016104396A (ru) | Лекарственные формы, соли и полиморфы транснорсертралина и их применения | |
| JP2013520412A5 (enExample) | ||
| Lokhande et al. | Microwave assisted synthesized bimetallic Ti and V based MXene for anticancer application | |
| GB201220630D0 (en) | Kissorphin peptides for use in the treatment of alzheimer's disease, creutzfeldtjakob disease or diabetes mellitus | |
| JP2016520122A5 (enExample) | ||
| IL273920B1 (en) | Solid forms of 3-(5-fluorobenzofuran-3-yl)-4-(5-methyl-5h-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione | |
| JP2018500355A5 (enExample) | ||
| Qin et al. | Strong convergence for three classes of uniformly equi-continuous and asymptotically quasi-nonexpansive mappings | |
| RU2016145264A (ru) | Соли и полиморфы замещенного имидазопиридинил-аминопиридина |