HRP20220031T1 - Kristalni trihidratni oblik (3s,3s') 4,4'-disulfanedilbis (3-aminobutan 1-sulfonske kiseline) - Google Patents
Kristalni trihidratni oblik (3s,3s') 4,4'-disulfanedilbis (3-aminobutan 1-sulfonske kiseline) Download PDFInfo
- Publication number
- HRP20220031T1 HRP20220031T1 HRP20220031TT HRP20220031T HRP20220031T1 HR P20220031 T1 HRP20220031 T1 HR P20220031T1 HR P20220031T T HRP20220031T T HR P20220031TT HR P20220031 T HRP20220031 T HR P20220031T HR P20220031 T1 HRP20220031 T1 HR P20220031T1
- Authority
- HR
- Croatia
- Prior art keywords
- aminobutane
- sulfonic acid
- disulfanediylbis
- trihydrate form
- crystalline trihydrate
- Prior art date
Links
- 150000004684 trihydrates Chemical group 0.000 title claims 2
- HJPXZXVKLGEMGP-YUMQZZPRSA-N (3s)-3-amino-4-[[(2s)-2-amino-4-sulfobutyl]disulfanyl]butane-1-sulfonic acid Chemical compound OS(=O)(=O)CC[C@H](N)CSSC[C@@H](N)CCS(O)(=O)=O HJPXZXVKLGEMGP-YUMQZZPRSA-N 0.000 title 1
- HJPXZXVKLGEMGP-UHFFFAOYSA-N 3-amino-4-[(2-amino-4-sulfobutyl)disulfanyl]butane-1-sulfonic acid Chemical compound OS(=O)(=O)CCC(N)CSSCC(N)CCS(O)(=O)=O HJPXZXVKLGEMGP-UHFFFAOYSA-N 0.000 claims 1
- 238000002441 X-ray diffraction Methods 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
- C07C319/24—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides by reactions involving the formation of sulfur-to-sulfur bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
- C07C321/12—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms
- C07C321/14—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/64—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
- C07C323/66—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Claims (1)
1. Kristalni trihidratni oblik (3S,3S') 4,4'-disulfandiilbis(3-aminobutan 1-sulfonske kiseline), naznačen time što pokazuje sljedeća svojstva difrakcije X-zraka:
[image]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10306099A EP2439192A1 (en) | 2010-10-07 | 2010-10-07 | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
EP18177972.9A EP3395796B1 (en) | 2010-10-07 | 2011-10-07 | A crystalline trihydrate form of (3s,3s') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20220031T1 true HRP20220031T1 (hr) | 2022-04-01 |
Family
ID=43558332
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20220031TT HRP20220031T1 (hr) | 2010-10-07 | 2011-10-07 | Kristalni trihidratni oblik (3s,3s') 4,4'-disulfanedilbis (3-aminobutan 1-sulfonske kiseline) |
HRP20181437TT HRP20181437T1 (hr) | 2010-10-07 | 2018-09-07 | Postupak proizvodnje (3s,3s') 4,4' disulfanedilbis (3-aminobutan-1-sulfonske kiseline) |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HRP20181437TT HRP20181437T1 (hr) | 2010-10-07 | 2018-09-07 | Postupak proizvodnje (3s,3s') 4,4' disulfanedilbis (3-aminobutan-1-sulfonske kiseline) |
Country Status (25)
Country | Link |
---|---|
US (2) | US9187418B2 (hr) |
EP (3) | EP2439192A1 (hr) |
JP (1) | JP5921556B2 (hr) |
KR (2) | KR101869366B1 (hr) |
CN (1) | CN103228624B (hr) |
AR (1) | AR083360A1 (hr) |
AU (1) | AU2011311483B2 (hr) |
BR (2) | BR122021023430B1 (hr) |
CA (2) | CA3016057C (hr) |
CY (2) | CY1120859T1 (hr) |
DK (2) | DK3395796T3 (hr) |
EA (1) | EA021612B1 (hr) |
ES (2) | ES2689246T3 (hr) |
HR (2) | HRP20220031T1 (hr) |
HU (2) | HUE058031T2 (hr) |
IL (1) | IL225557A (hr) |
LT (2) | LT2625163T (hr) |
MX (1) | MX2013003863A (hr) |
NZ (1) | NZ608971A (hr) |
PL (2) | PL3395796T3 (hr) |
PT (2) | PT2625163T (hr) |
RS (2) | RS62838B1 (hr) |
SI (2) | SI2625163T1 (hr) |
TW (1) | TWI532710B (hr) |
WO (1) | WO2012045849A1 (hr) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2439192A1 (en) | 2010-10-07 | 2012-04-11 | Quantum Genomics | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
EP2722327A1 (en) | 2012-10-22 | 2014-04-23 | Quantum Genomics | Crystalline phase of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) with L-lysine |
US10501426B1 (en) | 2019-01-11 | 2019-12-10 | King Saud University | Synthesis of thiazole derivative as anticancer and anti-antibiotics resistant bacteria agent |
TW202100146A (zh) | 2019-03-11 | 2021-01-01 | 法商量子基因科技有限公司 | 用於治療高血壓或心衰竭的化合物及包含其之組成物 |
CN111892557B (zh) * | 2019-05-05 | 2022-11-08 | 河北圣泰材料股份有限公司 | 哌嗪类成膜离子液体的合成方法 |
WO2022225712A1 (en) * | 2021-04-22 | 2022-10-27 | Teva Pharmaceuticals International Gmbh | Solid state forms of firibastat and processes for preparation thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5596095A (en) * | 1994-12-12 | 1997-01-21 | Procept, Inc. | Formation and utility of sulfonic acid protecting groups |
WO2004007441A2 (fr) | 2002-07-16 | 2004-01-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Derives de 4,4' -dithiobis- (3-aminobutane-1-sulfonates) nouveaux et compositions les contenant |
FR2858617A1 (fr) * | 2003-08-06 | 2005-02-11 | Inst Nat Sante Rech Med | Derives de 4',4'-dithiobis-(3-aminobutane-1-sulfonate-1- sulfonates) nouveaux et compositions les contenant |
CN101845003A (zh) * | 2010-01-29 | 2010-09-29 | 华东理工大学 | N-三(羟甲基)甲基-3-氨基丙磺酸化合物及其制备方法 |
EP2439192A1 (en) | 2010-10-07 | 2012-04-11 | Quantum Genomics | Method for the preparation of (3S,3S') 4,4'-disulfanediylbis (3-aminobutane 1-sulfonic acid) |
-
2010
- 2010-10-07 EP EP10306099A patent/EP2439192A1/en not_active Withdrawn
-
2011
- 2011-10-06 TW TW100136334A patent/TWI532710B/zh active
- 2011-10-07 ES ES11769843.1T patent/ES2689246T3/es active Active
- 2011-10-07 BR BR122021023430-2A patent/BR122021023430B1/pt active IP Right Grant
- 2011-10-07 LT LTEP11769843.1T patent/LT2625163T/lt unknown
- 2011-10-07 WO PCT/EP2011/067524 patent/WO2012045849A1/en active Application Filing
- 2011-10-07 HR HRP20220031TT patent/HRP20220031T1/hr unknown
- 2011-10-07 LT LTEP18177972.9T patent/LT3395796T/lt unknown
- 2011-10-07 KR KR1020137011888A patent/KR101869366B1/ko active IP Right Grant
- 2011-10-07 EP EP18177972.9A patent/EP3395796B1/en active Active
- 2011-10-07 CA CA3016057A patent/CA3016057C/en active Active
- 2011-10-07 KR KR1020187008022A patent/KR101893894B1/ko active IP Right Grant
- 2011-10-07 EA EA201300440A patent/EA021612B1/ru unknown
- 2011-10-07 HU HUE18177972A patent/HUE058031T2/hu unknown
- 2011-10-07 SI SI201131578T patent/SI2625163T1/sl unknown
- 2011-10-07 RS RS20211589A patent/RS62838B1/sr unknown
- 2011-10-07 JP JP2013532214A patent/JP5921556B2/ja active Active
- 2011-10-07 NZ NZ608971A patent/NZ608971A/en unknown
- 2011-10-07 AU AU2011311483A patent/AU2011311483B2/en active Active
- 2011-10-07 DK DK18177972.9T patent/DK3395796T3/da active
- 2011-10-07 EP EP11769843.1A patent/EP2625163B1/en active Active
- 2011-10-07 CA CA2813834A patent/CA2813834C/en active Active
- 2011-10-07 PT PT11769843T patent/PT2625163T/pt unknown
- 2011-10-07 ES ES18177972T patent/ES2903434T3/es active Active
- 2011-10-07 RS RS20181090A patent/RS57670B1/sr unknown
- 2011-10-07 CN CN201180056371.6A patent/CN103228624B/zh active Active
- 2011-10-07 MX MX2013003863A patent/MX2013003863A/es active IP Right Grant
- 2011-10-07 PL PL18177972T patent/PL3395796T3/pl unknown
- 2011-10-07 SI SI201132028T patent/SI3395796T1/sl unknown
- 2011-10-07 PT PT181779729T patent/PT3395796T/pt unknown
- 2011-10-07 US US13/878,003 patent/US9187418B2/en active Active
- 2011-10-07 PL PL11769843T patent/PL2625163T3/pl unknown
- 2011-10-07 HU HUE11769843A patent/HUE040484T2/hu unknown
- 2011-10-07 DK DK11769843.1T patent/DK2625163T3/en active
- 2011-10-07 BR BR112013008404-9A patent/BR112013008404B1/pt active IP Right Grant
- 2011-10-11 AR ARP110103726A patent/AR083360A1/es active IP Right Grant
-
2013
- 2013-04-04 IL IL225557A patent/IL225557A/en active IP Right Grant
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2015
- 2015-10-27 US US14/923,615 patent/US9340497B2/en active Active
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2018
- 2018-09-07 HR HRP20181437TT patent/HRP20181437T1/hr unknown
- 2018-09-19 CY CY181100970T patent/CY1120859T1/el unknown
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2022
- 2022-01-13 CY CY20221100031T patent/CY1124919T1/el unknown
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