JP2010180242A5 - - Google Patents

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Publication number
JP2010180242A5
JP2010180242A5 JP2010098844A JP2010098844A JP2010180242A5 JP 2010180242 A5 JP2010180242 A5 JP 2010180242A5 JP 2010098844 A JP2010098844 A JP 2010098844A JP 2010098844 A JP2010098844 A JP 2010098844A JP 2010180242 A5 JP2010180242 A5 JP 2010180242A5
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JP
Japan
Prior art keywords
acid
compound
formula
malic
chemical formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2010098844A
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English (en)
Japanese (ja)
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JP5650924B2 (ja
JP2010180242A (ja
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Publication date
Priority claimed from DE19955190A external-priority patent/DE19955190A1/de
Application filed filed Critical
Publication of JP2010180242A publication Critical patent/JP2010180242A/ja
Publication of JP2010180242A5 publication Critical patent/JP2010180242A5/ja
Application granted granted Critical
Publication of JP5650924B2 publication Critical patent/JP5650924B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2010098844A 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩 Expired - Lifetime JP5650924B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19955190A DE19955190A1 (de) 1999-11-16 1999-11-16 Stabile Salze neuartiger Derivate von 3,3-Diphenylpropylaminen
DE19955190.1 1999-11-16

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2007042774A Division JP2007137895A (ja) 1999-11-16 2007-02-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011096911A Division JP5290351B2 (ja) 1999-11-16 2011-04-25 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Publications (3)

Publication Number Publication Date
JP2010180242A JP2010180242A (ja) 2010-08-19
JP2010180242A5 true JP2010180242A5 (https=) 2011-09-08
JP5650924B2 JP5650924B2 (ja) 2015-01-07

Family

ID=7929277

Family Applications (6)

Application Number Title Priority Date Filing Date
JP2001537950A Expired - Lifetime JP4083431B2 (ja) 1999-11-16 2000-11-15 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2007042774A Pending JP2007137895A (ja) 1999-11-16 2007-02-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098844A Expired - Lifetime JP5650924B2 (ja) 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2010098845A Expired - Lifetime JP5503393B2 (ja) 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2011096911A Expired - Lifetime JP5290351B2 (ja) 1999-11-16 2011-04-25 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2013229622A Expired - Lifetime JP5717824B2 (ja) 1999-11-16 2013-11-05 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2001537950A Expired - Lifetime JP4083431B2 (ja) 1999-11-16 2000-11-15 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2007042774A Pending JP2007137895A (ja) 1999-11-16 2007-02-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2010098845A Expired - Lifetime JP5503393B2 (ja) 1999-11-16 2010-04-22 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2011096911A Expired - Lifetime JP5290351B2 (ja) 1999-11-16 2011-04-25 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩
JP2013229622A Expired - Lifetime JP5717824B2 (ja) 1999-11-16 2013-11-05 ３，３−ジフェニルプロピルアミン類の新規誘導体の安定な塩

Country Status (30)

Country Link
US (1) US6858650B1 (https=)
EP (3) EP1481964B1 (https=)
JP (6) JP4083431B2 (https=)
KR (2) KR100563149B1 (https=)
CN (1) CN1215045C (https=)
AT (3) ATE395056T1 (https=)
AU (1) AU778132B2 (https=)
BR (1) BRPI0015610C1 (https=)
CA (1) CA2389749C (https=)
CY (2) CY1106204T1 (https=)
CZ (2) CZ302967B6 (https=)
DE (5) DE29923134U1 (https=)
DK (3) DK1481964T3 (https=)
EA (1) EA005588B1 (https=)
ES (3) ES2270240T3 (https=)
GE (1) GEP20084430B (https=)
HK (1) HK1045148B (https=)
HU (2) HU228197B1 (https=)
IL (2) IL149567A0 (https=)
IS (2) IS2124B (https=)
MX (1) MXPA02004603A (https=)
NO (2) NO323920B1 (https=)
NZ (1) NZ519230A (https=)
PL (1) PL201422B1 (https=)
PT (3) PT1481964E (https=)
SI (3) SI1230209T1 (https=)
SK (3) SK288185B6 (https=)
UA (2) UA73324C2 (https=)
WO (1) WO2001035957A1 (https=)
ZA (1) ZA200203315B (https=)

Families Citing this family (48)

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EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE29923134U1 (de) * 1999-11-16 2000-06-29 Schwarz Pharma Ag, 40789 Monheim Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen
DE10028443C1 (de) * 2000-06-14 2002-05-29 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von 3,3-Diarylpropylaminen, (R,S)- und (R)-4-Phenyl-2-chromanon-6-carbonsäure sowie (R)-4-Phenyl-2-chromanon-carbonsäure-cinchonidinsalz und deren Verwendung zur Herstellung eines rechtsdrehenden Hydroxybenzylalkohols und von pharmazeutischen Zusammensetzungen
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
DE10315878B4 (de) * 2003-04-08 2009-06-04 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Fesoterodin und Verwendung
WO2005012227A2 (en) * 2003-08-05 2005-02-10 Ranbaxy Laboratories Limited Process for preparation of 2-(3-diisopropylamino-1-phenylpropyl)-4-hydroxymethyl-phenol, a metabolite of tolterodine
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
US8034823B2 (en) * 2005-02-22 2011-10-11 Savvipharm Inc Method of increasing drug oral bioavailability and compositions of less toxic orotate salts
KR100647068B1 (ko) 2005-09-15 2006-11-23 하나제약 주식회사 라세믹ｎ,ｎ-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법
DE602007009096D1 (de) * 2006-05-24 2010-10-21 Pfizer Ltd Verfahren zur herstellung von benzopyran-2-olderivaten
US8344176B2 (en) * 2006-05-31 2013-01-01 Schwarz Pharma Ltd. Synthesis of substituted hydroxymethyl phenols
EP1862449A1 (en) * 2006-05-31 2007-12-05 Schwarz Pharma Ltd. A shortened synthesis of substituted hydroxymethyl phenols
IES20060424A2 (en) * 2006-06-08 2007-10-31 Schwarz Pharma Ltd Accelerated synthesis of (3-Diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)phenol and its phenolic monoesters
ATE477234T1 (de) 2006-06-09 2010-08-15 Schwarz Pharma Ltd Synthese von phenolischen estern von hydroxymethylphenolen
JP4743321B2 (ja) * 2006-06-09 2011-08-10 ウーツェーベー ファルマ ゲーエムベーハー フェソテロジンを含む安定した医薬組成物
US7807715B2 (en) 2006-06-09 2010-10-05 Ucb Pharma Gmbh Pharmaceutical compositions comprising fesoterodine
IES20060435A2 (en) 2006-06-12 2007-12-12 Schwarz Pharma Ltd Shortened synthesis using paraformaldehyde or trioxane
BRPI0712842A2 (pt) * 2006-06-12 2012-07-24 Sanol Arznei Schwarz Gmbh internediÁrio quiral, processo para produÇço do mesmo e seu emprego na fabricaÇço da tolterodina, fesoterodina ou o metabàlito ativo das mesmas.
US20100217034A1 (en) * 2007-09-21 2010-08-26 Actavis Group Ptc Ehf Process for the Preparation of Fesoterodine
US20100297241A1 (en) * 2007-10-01 2010-11-25 Actavis Group Ptc Ehf Amorphous Fesoterodine Fumarate
US20110086103A1 (en) * 2008-04-04 2011-04-14 Actavis Group Ptc Ehf Novel mandelate salt of fesoterodine
WO2010010464A2 (en) * 2008-07-21 2010-01-28 Actavis Group Ptc Ehf Fesoterodine substantially free of dehydroxy impurity
IT1392082B1 (it) * 2008-12-10 2012-02-09 Chemi Spa Nuove forme solide della fesoterodina fumarato
WO2010130392A1 (de) 2009-05-11 2010-11-18 Ratiopharm Gmbh Desfesoterodin in form eines weinsäuresalzes
IT1394219B1 (it) 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina fumarato di elevata purezza.
IT1394217B1 (it) * 2009-05-15 2012-06-01 Chemi Spa Metodo di preparazione di fesoterodina e/o fesoterodina fumarato.
KR20120053027A (ko) 2009-09-03 2012-05-24 테바 기오기스제르갸르 자르트쾨렌 뮈쾨되 레스즈베니타르사사그 페소테로딘 푸마레이트 및 페소테로딘 염기의 결정형
IT1396373B1 (it) * 2009-10-29 2012-11-19 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina.
EP2316432A1 (de) 2009-10-30 2011-05-04 ratiopharm GmbH Zusammensetzung enthaltend Fesoterodin und Ballaststoffe
US20110124903A1 (en) * 2009-11-20 2011-05-26 Actavis Group Ptc Ehf Solid state forms of fesoterodine intermediates
IT1397521B1 (it) * 2009-12-21 2013-01-16 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina con un basso contenuto di impurezze.
IT1397920B1 (it) * 2010-02-08 2013-02-04 Dipharma Francis Srl Forma cristallina di fesoterodina fumarato e procedimento per la sua preparazione
US20130172411A1 (en) 2010-03-22 2013-07-04 Cadila Healthcare Limited Stable pharmaceutical compositions comprising fesoterodine
JP5812500B2 (ja) 2010-04-30 2015-11-17 メルク・シャープ・エンド・ドーム・コーポレイション 新規なβ３アドレナリン作動性受容体アゴニスト
WO2011141932A2 (en) 2010-05-11 2011-11-17 Intas Pharmaceuticals Limited Process for preparation of phenolic monoesters of hydroxymethyl phenols
WO2011145019A1 (en) * 2010-05-17 2011-11-24 Orchid Chemicals And Pharmaceuticals Limited Improved process for diphenylpropylamine derivatives
IT1401451B1 (it) 2010-06-10 2013-07-26 Chemi Spa Nuovo processo di preparazione di 2-idrossi-4-fenil-3,4-diidro-2h-cromen-6-il-metanolo e (r)-2-[3-(diisopropilammino)-1-fenilpropil]-4-(idrossimetil)fenolo.
WO2011158257A1 (en) 2010-06-18 2011-12-22 Panacea Biotec Ltd Preparation process of fesoterodine and intermediates
WO2012025941A2 (en) 2010-08-25 2012-03-01 Cadila Healthcare Limited Processes for the preparation of fesoterodine
IT1403094B1 (it) * 2010-12-09 2013-10-04 Dipharma Francis Srl Procedimento per la preparazione di fesoterodina o un suo sale
WO2012098560A2 (en) * 2011-01-17 2012-07-26 Msn Laboratories Limited Process for the preparation of muscarinic receptor antagonist
TWI520732B (zh) 2011-01-18 2016-02-11 輝瑞有限公司 固體分子分散液
EP2508173A1 (en) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Stabilized pharmaceutical composition comprising fesoterodine
EP2508175A1 (en) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Pharmaceutical composition comprising fesoterodine or a salt or a solvate thereof
US9422228B2 (en) 2012-05-04 2016-08-23 Crystal Pharma, S.A.U. Process for the preparation of optically pure fesoterodine derivatives
ITMI20121232A1 (it) 2012-07-16 2014-01-17 Cambrex Profarmaco Milano Srl Procedimento per la preparazione di 2-(3-n,n-diisopropilamino-1-fenilpropil)-4-idrossimetil-fenolo e suoi derivati
TR201721437A2 (tr) 2017-12-25 2019-07-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Fesoterodi̇ni̇n modi̇fi̇ye salim sağlayan formülasyonlari
EP4237405A1 (en) * 2020-10-27 2023-09-06 Wella Germany GmbH 2-methoxymethyl-p-phenylenediamine in cosmetic grade quality

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GR75395B (https=) * 1980-11-14 1984-07-13 Lilly Co Eli
IL66831A0 (en) * 1981-10-05 1982-12-31 Kefalas As Indane derivatives
SE8800207D0 (sv) * 1988-01-22 1988-01-22 Kabivitrum Ab Nya aminer, deras anvendning och framstellning
ATE140213T1 (de) * 1990-03-08 1996-07-15 Fujisawa Pharmaceutical Co N-monosubstituierte cyclopentenylamine, ein verfahren zu ihrer herstellung, und ihre verwendung als medikament
JPH0483431A (ja) * 1990-07-26 1992-03-17 Seiko Epson Corp 選択呼出受信機
SE9203318D0 (sv) 1992-11-06 1992-11-06 Kabi Pharmacia Ab Novel 3,3-diphenylpropylamines, their use and preparation
SE9701144D0 (sv) * 1997-03-27 1997-03-27 Pharmacia & Upjohn Ab Novel compounds, their use and preparation
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
DE29923134U1 (de) * 1999-11-16 2000-06-29 Schwarz Pharma Ag, 40789 Monheim Stabile Salze neuartiger Derviate von 3,3-Diphenylpropylaminen

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