|
US7219016B2
(en)
|
2001-04-20 |
2007-05-15 |
Yale University |
Systems and methods for automated analysis of cells and tissues
|
|
DK1392359T4
(da)
|
2001-05-11 |
2013-06-10 |
Ludwig Inst For Cancer Res Ltd |
Specifikke bindingsproteiner og deres anvendelser.
|
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
|
CN107988363A
(zh)
|
2004-03-31 |
2018-05-04 |
综合医院公司 |
测定癌症对表皮生长因子受体靶向性治疗反应性的方法
|
|
JP2008504809A
(ja)
|
2004-06-04 |
2008-02-21 |
ジェネンテック・インコーポレーテッド |
Egfr突然変異
|
|
TW200617396A
(en)
*
|
2004-10-06 |
2006-06-01 |
Astrazeneca Ab |
Method
|
|
KR101424812B1
(ko)
*
|
2004-10-18 |
2014-08-07 |
브랜데이스 유니버시티 |
핵산 증폭을 위한 프라이머, 프로브 및 방법
|
|
WO2006070667A1
(ja)
*
|
2004-12-28 |
2006-07-06 |
Takara Bio Inc. |
Egfr遺伝子変異の検出法ならびに検出キット
|
|
PL1848414T3
(pl)
|
2005-02-03 |
2011-10-31 |
Wyeth Llc |
Sposób leczenia nowotworu opornego na gefitinib
|
|
EP2505591A1
(en)
|
2005-02-11 |
2012-10-03 |
Memorial Sloan-Kettering Cancer Center |
Methods and compositions for detecting a drug resistant EGFR mutant
|
|
JP2008535477A
(ja)
*
|
2005-02-24 |
2008-09-04 |
アムジエン・インコーポレーテツド |
上皮成長因子受容体変異
|
|
GB0506670D0
(en)
*
|
2005-04-01 |
2005-05-11 |
Astrazeneca Ab |
Method
|
|
GB2424886A
(en)
*
|
2005-04-04 |
2006-10-11 |
Dxs Ltd |
Polynucleotide primers against epidermal growth factor receptor and method of detecting gene mutations
|
|
GB2427468B
(en)
|
2005-04-05 |
2011-03-02 |
Cellpoint Diagnostics |
Cell separation device and method for the detection of EpCAM positive cells
|
|
WO2006113151A2
(en)
*
|
2005-04-14 |
2006-10-26 |
Wyeth |
Use of an epidermal growth factor receptor kinase inhibitor (egfr) in gefitinib resistant patients
|
|
WO2007001868A1
(en)
*
|
2005-06-28 |
2007-01-04 |
Genentech, Inc. |
Egfr and kras mutations
|
|
JP2009511008A
(ja)
*
|
2005-10-05 |
2009-03-19 |
アストラゼネカ ユーケー リミテッド |
ErbB受容体薬に対する患者の応答を予測またはモニタリングする方法
|
|
WO2007056118A1
(en)
|
2005-11-04 |
2007-05-18 |
Wyeth |
Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
|
|
CA2833706C
(en)
*
|
2005-11-11 |
2014-10-21 |
Boehringer Ingelheim International Gmbh |
Quinazoline derivatives for the treatment of cancer diseases
|
|
SI1948180T1
(sl)
*
|
2005-11-11 |
2013-06-28 |
Boehringer Ingelheim International Gmbh |
Kombinacijsko zdravljenje raka, ki obsega EGFR/HER2 inhibitorje
|
|
JPWO2007099852A1
(ja)
*
|
2006-02-23 |
2009-07-16 |
国立大学法人金沢大学 |
固形癌のチロシンキナーゼ阻害剤に対する感受性を検査する方法及び検査キット
|
|
US7736905B2
(en)
|
2006-03-31 |
2010-06-15 |
Biodesix, Inc. |
Method and system for determining whether a drug will be effective on a patient with a disease
|
|
US7867775B2
(en)
*
|
2006-03-31 |
2011-01-11 |
Biodesix, Inc. |
Selection of head and neck cancer patients for treatment with drugs targeting EGFR pathway
|
|
US7906342B2
(en)
|
2006-03-31 |
2011-03-15 |
Biodesix, Inc. |
Monitoring treatment of cancer patients with drugs targeting EGFR pathway using mass spectrometry of patient samples
|
|
CA2650776A1
(en)
|
2006-05-05 |
2007-11-15 |
Yale University |
Immunohistochemical methods for determining signal transduction activity in tumors
|
|
US12366585B2
(en)
|
2006-05-18 |
2025-07-22 |
Caris Mpi, Inc. |
Molecular profiling of tumors
|
|
EP3399450A1
(en)
*
|
2006-05-18 |
2018-11-07 |
Caris MPI, Inc. |
System and method for determining individualized medical intervention for a disease state
|
|
US8768629B2
(en)
*
|
2009-02-11 |
2014-07-01 |
Caris Mpi, Inc. |
Molecular profiling of tumors
|
|
EP2589668A1
(en)
|
2006-06-14 |
2013-05-08 |
Verinata Health, Inc |
Rare cell analysis using sample splitting and DNA tags
|
|
CN108048549B
(zh)
|
2006-06-14 |
2021-10-26 |
维里纳塔健康公司 |
使用样品拆分和dna标签进行稀有细胞分析
|
|
JP2009544007A
(ja)
*
|
2006-07-13 |
2009-12-10 |
イェール・ユニバーシティー |
バイオマーカーの細胞内局在性に基づいて癌予後を行う方法
|
|
AU2007299080B2
(en)
*
|
2006-09-18 |
2013-04-18 |
Boehringer Ingelheim International Gmbh |
Method for treating cancer harboring EGFR mutations
|
|
JPWO2008038812A1
(ja)
*
|
2006-09-28 |
2010-01-28 |
株式会社島津製作所 |
マトリックス支援レーザー脱離イオン化質量分析用サンプル調製法及びマトリックス支援レーザー脱離イオン化質量分析法
|
|
JP4795203B2
(ja)
*
|
2006-11-13 |
2011-10-19 |
シスメックス株式会社 |
アンスラサイクリン系抗癌剤の感受性判定方法及びそのシステム
|
|
MX2009007987A
(es)
|
2007-01-25 |
2010-03-01 |
Dana Farber Cancer Inst Inc |
Uso de anticuerpos anti-egfr en el tratamiento de enfermedad mediada por egfr mutante.
|
|
SI2129396T1
(sl)
*
|
2007-02-16 |
2013-12-31 |
Merrimack Pharmaceuticals, Inc. |
Protitelesa proti ErbB3 in njihove uporabe
|
|
AU2008226808B2
(en)
*
|
2007-03-13 |
2013-04-18 |
Amgen Inc. |
K-ras and B-raf mutations and anti-EGFr antibody therapy
|
|
HUE033695T2
(en)
|
2007-03-13 |
2017-12-28 |
Amgen Inc |
K-RAS mutations and anti-EGFR antibody therapy
|
|
WO2008115404A1
(en)
|
2007-03-15 |
2008-09-25 |
Ludwing Institute For Cancer Research |
Treatment method using egfr antibodies and src inhibitors and related formulations
|
|
US8642067B2
(en)
|
2007-04-02 |
2014-02-04 |
Allergen, Inc. |
Methods and compositions for intraocular administration to treat ocular conditions
|
|
US8999634B2
(en)
|
2007-04-27 |
2015-04-07 |
Quest Diagnostics Investments Incorporated |
Nucleic acid detection combining amplification with fragmentation
|
|
AU2008250033A1
(en)
|
2007-05-11 |
2008-11-20 |
Enzon Pharmaceuticals, Inc. |
RNA antagonist compounds for the modulation of HER3
|
|
WO2009005715A1
(en)
*
|
2007-06-29 |
2009-01-08 |
Yale University |
Methods for a predictive diagnostic test for tamoxifen
|
|
ES2609915T3
(es)
|
2007-08-14 |
2017-04-25 |
Ludwig Institute For Cancer Research Ltd. |
Anticuerpo monoclonal 175 direccionado al receptor de EGF y derivados y usos del mismo
|
|
US8022216B2
(en)
|
2007-10-17 |
2011-09-20 |
Wyeth Llc |
Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
|
|
EP2245199B1
(en)
|
2008-02-01 |
2013-11-13 |
The General Hospital Corporation |
Use of microvesicles in diagnosis, prognosis and treatment of medical diseases and conditions
|
|
WO2009124293A1
(en)
*
|
2008-04-03 |
2009-10-08 |
Hudson Alpha Institute For Biotechnology |
Amplicon rescue multiplex polymerase chain reaction for amplificaton of multiple targets
|
|
US8137919B2
(en)
*
|
2008-04-10 |
2012-03-20 |
Montefiore Medical Center |
Method of determining the sensitivity of cancer cells to EGFR inhibitors including cetuximab, panitumumab and erlotinib
|
|
CN101445829B
(zh)
*
|
2008-04-23 |
2013-06-05 |
广州益善生物技术有限公司 |
Egfr基因突变位点的检测探针、液相芯片及其检测方法
|
|
CA2725598C
(en)
|
2008-06-17 |
2013-10-08 |
Wyeth Llc |
Antineoplastic combinations containing hki-272 and vinorelbine
|
|
SMT201700084T1
(it)
|
2008-08-04 |
2017-03-08 |
Wyeth Llc |
Associazioni antineoplastiche di 4-anilino-3-cianochinoline e capecitabina
|
|
BRPI0917871A2
(pt)
*
|
2008-08-15 |
2017-06-20 |
Merrimack Pharmaceuticals Inc |
agente terapêutico anti-erbb3 para uso em terapia de um tumor, métodos para predizer responsividade de um tumor de um agente terapêutco anti-erbb3, para selecionar terapia anti-erbb3 para um paciente, para predizer a resposta de células ao tratamento com um agente terapêutico, para identificar um biomarcador, e para evitar administração de uma droga para câncer anti-erbb3, e, kit para predizer a resposta das células ao tratamento com um agente terapêutico
|
|
EP3216874A1
(en)
|
2008-09-05 |
2017-09-13 |
TOMA Biosciences, Inc. |
Methods for stratifying and annotating cancer drug treatment options
|
|
US9598725B2
(en)
|
2010-03-02 |
2017-03-21 |
Bio-Rad Laboratories, Inc. |
Emulsion chemistry for encapsulated droplets
|
|
US8633015B2
(en)
|
2008-09-23 |
2014-01-21 |
Bio-Rad Laboratories, Inc. |
Flow-based thermocycling system with thermoelectric cooler
|
|
US12162008B2
(en)
|
2008-09-23 |
2024-12-10 |
Bio-Rad Laboratories, Inc. |
Partition-based method of analysis
|
|
US8951939B2
(en)
|
2011-07-12 |
2015-02-10 |
Bio-Rad Laboratories, Inc. |
Digital assays with multiplexed detection of two or more targets in the same optical channel
|
|
US10512910B2
(en)
|
2008-09-23 |
2019-12-24 |
Bio-Rad Laboratories, Inc. |
Droplet-based analysis method
|
|
US12090480B2
(en)
|
2008-09-23 |
2024-09-17 |
Bio-Rad Laboratories, Inc. |
Partition-based method of analysis
|
|
US9417190B2
(en)
|
2008-09-23 |
2016-08-16 |
Bio-Rad Laboratories, Inc. |
Calibrations and controls for droplet-based assays
|
|
WO2011120020A1
(en)
|
2010-03-25 |
2011-09-29 |
Quantalife, Inc. |
Droplet transport system for detection
|
|
US9132394B2
(en)
|
2008-09-23 |
2015-09-15 |
Bio-Rad Laboratories, Inc. |
System for detection of spaced droplets
|
|
US9492797B2
(en)
|
2008-09-23 |
2016-11-15 |
Bio-Rad Laboratories, Inc. |
System for detection of spaced droplets
|
|
US8709762B2
(en)
|
2010-03-02 |
2014-04-29 |
Bio-Rad Laboratories, Inc. |
System for hot-start amplification via a multiple emulsion
|
|
CA3149293C
(en)
|
2008-09-23 |
2023-09-12 |
Bio-Rad Laboratories, Inc. |
Droplet-based assay system
|
|
US11130128B2
(en)
|
2008-09-23 |
2021-09-28 |
Bio-Rad Laboratories, Inc. |
Detection method for a target nucleic acid
|
|
US9764322B2
(en)
|
2008-09-23 |
2017-09-19 |
Bio-Rad Laboratories, Inc. |
System for generating droplets with pressure monitoring
|
|
US9156010B2
(en)
|
2008-09-23 |
2015-10-13 |
Bio-Rad Laboratories, Inc. |
Droplet-based assay system
|
|
US8663920B2
(en)
|
2011-07-29 |
2014-03-04 |
Bio-Rad Laboratories, Inc. |
Library characterization by digital assay
|
|
EP2347009A4
(en)
*
|
2008-10-14 |
2012-05-30 |
Caris Mpi Inc |
GENE AND GENE EXPRESSED TARGET PROTEINS FOR THE PRESENTATION OF BIOMARKERS AND SIGNATURES BY TUMOR TYPE
|
|
PT3301446T
(pt)
*
|
2009-02-11 |
2020-07-14 |
Caris Mpi Inc |
Perfilagem molecular de tumores
|
|
GB2480980A
(en)
*
|
2009-03-02 |
2011-12-07 |
Trackfive Diagnostics Inc |
Methods for predicting cancer response to EGFR inhibitors
|
|
HUE061640T2
(hu)
|
2009-04-06 |
2023-07-28 |
Wyeth Llc |
Gyógykezelési rendszer mellrákhoz neratinib alkalmazásával
|
|
PL2451445T3
(pl)
|
2009-07-06 |
2019-09-30 |
Boehringer Ingelheim International Gmbh |
Sposób suszenia BIBW2992, jego soli i stałych preparatów farmaceutycznych zawierających tę substancję czynną
|
|
CA3106547C
(en)
|
2009-09-02 |
2022-07-05 |
Bio-Rad Laboratories, Inc. |
System for mixing fluids by coalescence of multiple emulsions
|
|
WO2011031892A1
(en)
|
2009-09-09 |
2011-03-17 |
The General Hospital Corporation |
Use of microvesicles in analyzing kras mutations
|
|
US20130005592A1
(en)
*
|
2009-09-10 |
2013-01-03 |
Board Of Regents Of The University Of Texas System |
Methods and compositions for predicting cancer therapy response
|
|
US7947653B1
(en)
|
2009-10-09 |
2011-05-24 |
Cold Spring Harbor Laboratory |
Methods for treating epidermal growth factor receptor tyrosine kinase inhibitor-resistant cancers
|
|
US8323883B1
(en)
|
2009-10-09 |
2012-12-04 |
Cold Spring Harbor Laboratory |
Methods of assessing therapeutic benefits of patients having cancers resistant to epidermal growth factor receptor kinase inhibitors
|
|
AU2010315362B2
(en)
|
2009-11-09 |
2015-01-22 |
Wyeth Llc |
Coated drug spheroids and uses thereof for eliminating or reducing conditions such as emesis and diarrhea
|
|
US20120316187A1
(en)
|
2009-11-13 |
2012-12-13 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
|
WO2011063416A2
(en)
|
2009-11-23 |
2011-05-26 |
The General Hospital Corporation |
Microfluidic devices for the capture of biological sample components
|
|
US10731221B2
(en)
|
2009-12-11 |
2020-08-04 |
Dignity Health |
Diagnosing IDH1 related subgroups and treatment of cancer
|
|
CA2781886A1
(en)
*
|
2009-12-11 |
2011-06-16 |
Dignity Health |
Pi3k/akt pathway subgroups in cancer: methods of using biomarkers for diagnosis and therapy
|
|
US20110224205A1
(en)
*
|
2010-02-11 |
2011-09-15 |
National Taiwan University |
Use of curcumin or its analogues in cancer therapy utilizing epidermal growth factor receptor tyrosine kinase inhibitor
|
|
DK2544680T3
(en)
|
2010-03-11 |
2015-04-27 |
Merrimack Pharmaceuticals Inc |
USE OF ErbB3 INHIBITORS IN TREATMENT OF TRIPLE-NEGATIVE BREAST CANCER
|
|
EP2548027A2
(en)
*
|
2010-03-18 |
2013-01-23 |
Institut National de la Santé et de la Recherche Médicale |
Method for predicting the responsiveness to chemotherapy
|
|
EP2550528B1
(en)
|
2010-03-25 |
2019-09-11 |
Bio-Rad Laboratories, Inc. |
Droplet generation for droplet-based assays
|
|
JP2013524169A
(ja)
|
2010-03-25 |
2013-06-17 |
クァンタライフ・インコーポレーテッド |
液滴によるアッセイ用の検出システム
|
|
CN102234683B
(zh)
*
|
2010-04-23 |
2013-07-17 |
广州益善生物技术有限公司 |
一种egfr基因突变检测液相芯片
|
|
CN101858909B
(zh)
*
|
2010-05-28 |
2013-07-03 |
广州瑞博奥生物科技有限公司 |
检测磷酸化表皮生长因子受体的试剂盒及其制备方法
|
|
US9309556B2
(en)
|
2010-09-24 |
2016-04-12 |
The Board Of Trustees Of The Leland Stanford Junior University |
Direct capture, amplification and sequencing of target DNA using immobilized primers
|
|
US9238812B2
(en)
|
2010-09-30 |
2016-01-19 |
Lsip, Llc |
Agent for suppressing expression of dominant mutant gene
|
|
AU2011320318B9
(en)
|
2010-10-29 |
2015-11-19 |
Immunogen, Inc. |
Non-antagonistic EGFR-binding molecules and immunoconjugates thereof
|
|
EA201390472A1
(ru)
|
2010-10-29 |
2014-02-28 |
Иммьюноджен, Инк. |
Новые молекулы, связывающиеся с egfr, и их иммуноконъюгаты
|
|
CA3024250C
(en)
|
2010-11-01 |
2022-01-04 |
Bio-Rad Laboratories, Inc. |
System for forming emulsions
|
|
WO2012065071A2
(en)
*
|
2010-11-12 |
2012-05-18 |
The Broad Institute Of Mit And Harvard |
Methods of predicting response to egfr antibody therapy
|
|
WO2012065705A1
(en)
|
2010-11-19 |
2012-05-24 |
Roche Diagnostics Gmbh |
Novel complex mutation in the epidermal growth factor receptor kinase domain
|
|
US20120164641A1
(en)
|
2010-12-22 |
2012-06-28 |
Roche Molecular Systems, Inc. |
Methods and Compositions for Detecting Mutation in the Human Epidermal Growth Factor Receptor Gene
|
|
CN102140518B
(zh)
*
|
2011-01-18 |
2013-02-06 |
杭州迪安医学检验中心有限公司 |
肺癌相关表皮生长因子受体egfr外显子突变定量检测试剂盒及方法
|
|
JP2014505257A
(ja)
|
2011-01-28 |
2014-02-27 |
バイオデシックス・インコーポレイテッド |
ホルモン療法および組み合わせ療法のための転移性乳癌患者の選択の予測試験
|
|
WO2012103442A2
(en)
|
2011-01-28 |
2012-08-02 |
The Broad Institute, Inc. |
Paired end bead amplification and high throughput sequencing
|
|
BR112013020773B1
(pt)
|
2011-02-15 |
2023-01-24 |
Leica Biosystems Newcastle Limited |
Método para a detecção localizada in situ de rna, método para a determinação da presença e da localização de uma sequência genética e método para a localização e/ou detecção in situ de um rna específico
|
|
US9556473B2
(en)
|
2011-02-15 |
2017-01-31 |
Leica Biosystems Newcastle Ltd |
Methods for identifying nucleic acid sequences
|
|
US12097495B2
(en)
|
2011-02-18 |
2024-09-24 |
Bio-Rad Laboratories, Inc. |
Methods and compositions for detecting genetic material
|
|
EP2492688A1
(en)
|
2011-02-23 |
2012-08-29 |
Pangaea Biotech, S.A. |
Molecular biomarkers for predicting response to antitumor treatment in lung cancer
|
|
WO2012129145A1
(en)
|
2011-03-18 |
2012-09-27 |
OSI Pharmaceuticals, LLC |
Nscle combination therapy
|
|
JP2014509865A
(ja)
|
2011-03-18 |
2014-04-24 |
バイオ−ラッド・ラボラトリーズ・インコーポレーテッド |
シグナルの組合せ使用による多重化デジタルアッセイ
|
|
EP3789498B1
(en)
|
2011-04-25 |
2025-08-13 |
Bio-Rad Laboratories, Inc. |
Methods for nucleic acid analysis
|
|
JP5930825B2
(ja)
*
|
2011-05-06 |
2016-06-08 |
アークレイ株式会社 |
Egfrエクソン19多型検出試験用試薬キット及びその用途
|
|
US9174216B2
(en)
|
2013-03-13 |
2015-11-03 |
DeNovo Science, Inc. |
System for capturing and analyzing cells
|
|
WO2013019491A1
(en)
|
2011-08-01 |
2013-02-07 |
Denovo Sciences |
Cell capture system and method of use
|
|
US9404864B2
(en)
|
2013-03-13 |
2016-08-02 |
Denovo Sciences, Inc. |
System for imaging captured cells
|
|
US10466160B2
(en)
|
2011-08-01 |
2019-11-05 |
Celsee Diagnostics, Inc. |
System and method for retrieving and analyzing particles
|
|
WO2013022961A1
(en)
|
2011-08-08 |
2013-02-14 |
3The Broad Institute |
Compositions and methods for co-amplifying subsequences of a nucleic acid fragment sequence
|
|
US9738935B2
(en)
*
|
2011-11-10 |
2017-08-22 |
Roche Molecular Systems, Inc. |
Complex mutations in the epidermal growth factor receptor kinase domain
|
|
CN104066481A
(zh)
|
2011-11-21 |
2014-09-24 |
伊缪诺金公司 |
利用egfr抗体细胞毒性剂缀合物治疗抗egfr疗法的肿瘤的方法
|
|
US9260714B2
(en)
|
2011-12-02 |
2016-02-16 |
Roche Molecular Systems, Inc. |
Suppression of non-specific amplification with high-homology oligonucleotides
|
|
KR101963230B1
(ko)
|
2011-12-26 |
2019-03-29 |
삼성전자주식회사 |
복수개의 단일 항체를 포함하는 단백질 복합체
|
|
WO2013155531A2
(en)
|
2012-04-13 |
2013-10-17 |
Bio-Rad Laboratories, Inc. |
Sample holder with a well having a wicking promoter
|
|
EP2653558B1
(en)
|
2012-04-18 |
2015-10-07 |
Roche Diagniostics GmbH |
A method of detecting nucleic acid targets using a statistical classifier
|
|
CN102732636B
(zh)
*
|
2012-07-17 |
2014-01-15 |
海南医学院 |
一种检测肿瘤细胞egfr基因突变的芯片
|
|
CN102851375B
(zh)
*
|
2012-09-11 |
2014-02-19 |
上海源奇生物医药科技有限公司 |
检测egfr基因突变的引物、探针及其试剂盒和使用方法
|
|
KR101911438B1
(ko)
*
|
2012-10-31 |
2018-10-24 |
삼성전자주식회사 |
이중 특이 항원 결합 단백질 복합체 및 이중 특이 항체의 제조 방법
|
|
US20140341884A1
(en)
*
|
2012-12-04 |
2014-11-20 |
Roche Molecular Systems, Inc. |
Novel Complex Mutations in the Epidermal Growth Factor Receptor Kinase Domain
|
|
US9752181B2
(en)
|
2013-01-26 |
2017-09-05 |
Denovo Sciences, Inc. |
System and method for capturing and analyzing cells
|
|
NO2964638T3
(enExample)
|
2013-03-06 |
2018-01-06 |
|
|
|
ES2662598T3
(es)
|
2013-03-08 |
2018-04-09 |
F. Hoffmann-La Roche Ag |
Análisis de sangre para la detección de mutaciones de EGFR
|
|
US20140287417A1
(en)
|
2013-03-08 |
2014-09-25 |
Roche Molecular Systems, Inc. |
EGFR Blood Monitoring
|
|
US9707562B2
(en)
|
2013-03-13 |
2017-07-18 |
Denovo Sciences, Inc. |
System for capturing and analyzing cells
|
|
US9856535B2
(en)
|
2013-05-31 |
2018-01-02 |
Denovo Sciences, Inc. |
System for isolating cells
|
|
US10391490B2
(en)
|
2013-05-31 |
2019-08-27 |
Celsee Diagnostics, Inc. |
System and method for isolating and analyzing cells
|
|
CN103333963A
(zh)
*
|
2013-06-09 |
2013-10-02 |
中国人民解放军第四军医大学 |
Egfr突变检测引物组及其用途
|
|
JP6463675B2
(ja)
*
|
2013-06-19 |
2019-02-06 |
学校法人 久留米大学 |
上皮成長因子受容体チロシンキナーゼ阻害薬の治療効果を予測する方法
|
|
AU2014287209B2
(en)
|
2013-07-09 |
2019-01-24 |
Dana-Farber Cancer Institute, Inc. |
Kinase inhibitors for the treatment of disease
|
|
WO2015100459A2
(en)
|
2013-12-27 |
2015-07-02 |
Merrimack Pharmaceuticals, Inc. |
Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies
|
|
US9242965B2
(en)
|
2013-12-31 |
2016-01-26 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
|
|
CN103923975B
(zh)
*
|
2014-01-27 |
2016-01-20 |
上海涌泰生物医药科技有限公司 |
一种检测egfr基因外显子19缺失突变的试剂盒和方法
|
|
US9211314B2
(en)
|
2014-04-04 |
2015-12-15 |
Biodesix, Inc. |
Treatment selection for lung cancer patients using mass spectrum of blood-based sample
|
|
WO2016015788A1
(en)
*
|
2014-07-28 |
2016-02-04 |
Fundació Institut Mar D'investigacions Mèdiques (Imim) |
Mutations in the extracellular domain iii of epidermal growth factor receptor gene
|
|
CA2961437C
(en)
|
2014-10-09 |
2019-01-15 |
F. Hoffmann-La Roche Ag |
Mutations in the epidermal growth factor receptor kinase domain
|
|
KR101692044B1
(ko)
*
|
2014-12-05 |
2017-01-04 |
사회복지법인 삼성생명공익재단 |
교모세포종에서 표피 성장인자 수용체 억제제의 치료 효과를 예측하는 방법
|
|
US20160333087A1
(en)
*
|
2015-05-12 |
2016-11-17 |
Bioven 3 Limited |
Methods and compositions for inhibition of egf/egfr pathway in combination with tyrosine kinase inhibitors
|
|
US10184006B2
(en)
|
2015-06-04 |
2019-01-22 |
Merrimack Pharmaceuticals, Inc. |
Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
|
|
KR20180069903A
(ko)
|
2015-11-02 |
2018-06-25 |
파이브 프라임 테라퓨틱스, 인크. |
Cd80 세포외 도메인 폴리펩타이드 및 이들의 암 치료에서의 용도
|
|
CN108701172A
(zh)
*
|
2016-02-12 |
2018-10-23 |
南托米克斯有限责任公司 |
高通量识别患者特异性新表位作为癌症免疫疗法的治疗靶点
|
|
CN105624309B
(zh)
*
|
2016-02-23 |
2020-04-21 |
深圳华大生命科学研究院 |
检测EGFR和/或K-ras基因突变的引物、探针及试剂盒
|
|
CN105866217B
(zh)
*
|
2016-03-21 |
2018-04-10 |
杭州市红十字会医院 |
三尖杉酯碱癌症治疗效果检测装置及方法
|
|
WO2017204577A1
(ko)
*
|
2016-05-25 |
2017-11-30 |
주식회사 젠큐릭스 |
상피세포 성장인자 수용체 유전자 돌연변이 검출용 조성물 및 이를 포함하는 키트
|
|
CA3060443A1
(en)
|
2017-04-19 |
2018-10-25 |
Board Of Regents, The University Of Texas System |
Immune cells expressing engineered antigen receptors
|
|
WO2018201584A1
(zh)
*
|
2017-05-03 |
2018-11-08 |
华为技术有限公司 |
基于竞争的传输方法和设备
|
|
US10299039B2
(en)
|
2017-06-02 |
2019-05-21 |
Apple Inc. |
Audio adaptation to room
|
|
US10391493B2
(en)
|
2017-08-29 |
2019-08-27 |
Celsee Diagnostics, Inc. |
System and method for isolating and analyzing cells
|
|
WO2019074920A1
(en)
*
|
2017-10-10 |
2019-04-18 |
Oncocyte Corporation |
METHODS AND COMPOSITIONS FOR THE DETECTION AND DIAGNOSIS OF BREAST CANCER
|
|
CN109722476A
(zh)
*
|
2017-10-31 |
2019-05-07 |
北京雅康博生物科技有限公司 |
用于检测egfr基因2237-2257位突变的引物、探针及试剂盒
|
|
EP3755349A4
(en)
|
2018-02-21 |
2021-11-17 |
Board of Regents, The University of Texas System |
PROCESS FOR ACTIVATION AND EXPANSION OF NATURAL KILLER CELLS AND THEIR USES
|
|
EP3788069A1
(en)
*
|
2018-05-01 |
2021-03-10 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors which recognize mutated egfr
|
|
WO2020080871A2
(ko)
*
|
2018-10-18 |
2020-04-23 |
(주)신테카바이오 |
암 약물 반응성 판단을 위한 바이오 마커 조성물, 바이오 마커 조성물을 이용한 암 약물 반응성 판단 방법 및 암 약물 반응성 판단을 위한 바이오 마커 조성물 검출용 진단칩
|
|
BR112021016149A2
(pt)
|
2019-02-26 |
2021-10-13 |
Janssen Biotech, Inc. |
Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met
|
|
US10633693B1
(en)
|
2019-04-16 |
2020-04-28 |
Celsee Diagnostics, Inc. |
System and method for leakage control in a particle capture system
|
|
US11273439B2
(en)
|
2019-05-07 |
2022-03-15 |
Bio-Rad Laboratories, Inc. |
System and method for target material retrieval from microwells
|
|
US11578322B2
(en)
|
2019-05-07 |
2023-02-14 |
Bio-Rad Laboratories, Inc. |
System and method for automated single cell processing
|
|
WO2020230091A1
(en)
|
2019-05-14 |
2020-11-19 |
Janssen Biotech, Inc. |
Combination therapies with bispecific anti-egfr/c-met antibodies and third generation egfr tyrosine kinase inhibitors
|
|
EP3982716A4
(en)
|
2019-06-14 |
2023-09-06 |
Bio-Rad Laboratories, Inc. |
System and method for automated single cell processing and analyses
|
|
GB2623904B
(en)
|
2019-11-06 |
2024-07-24 |
Univ Leland Stanford Junior |
Methods and systems for analyzing nucleic acid molecules
|
|
JOP20220184A1
(ar)
|
2020-02-12 |
2023-01-30 |
Janssen Biotech Inc |
علاج مصابي السرطان ممن لديهم طفرات تخطي c-Met إكسون14
|
|
US11211147B2
(en)
|
2020-02-18 |
2021-12-28 |
Tempus Labs, Inc. |
Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
|
|
US11211144B2
(en)
|
2020-02-18 |
2021-12-28 |
Tempus Labs, Inc. |
Methods and systems for refining copy number variation in a liquid biopsy assay
|
|
US11475981B2
(en)
|
2020-02-18 |
2022-10-18 |
Tempus Labs, Inc. |
Methods and systems for dynamic variant thresholding in a liquid biopsy assay
|
|
CN111154881A
(zh)
*
|
2020-03-09 |
2020-05-15 |
南京实践医学检验有限公司 |
一种急性髓系白血病中基因突变的检测试剂盒及应用
|
|
US11504719B2
(en)
|
2020-03-12 |
2022-11-22 |
Bio-Rad Laboratories, Inc. |
System and method for receiving and delivering a fluid for sample processing
|
|
US20220025453A1
(en)
*
|
2020-07-23 |
2022-01-27 |
Michael Y Sha |
Xenonucleic acid-mediated multiplex qpcr clamping technology for lung cancer mutation detection
|
|
CN114107449B
(zh)
*
|
2020-08-31 |
2024-04-09 |
中山大学孙逸仙纪念医院 |
一种单细胞内原位qPCR方法
|
|
CN111996193B
(zh)
*
|
2020-09-11 |
2024-02-20 |
北京键凯科技股份有限公司 |
一种有效抑制表皮生长因子受体表达的siRNA序列
|
|
US11783912B2
(en)
|
2021-05-05 |
2023-10-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and systems for analyzing nucleic acid molecules
|
|
CN113564255A
(zh)
*
|
2021-08-13 |
2021-10-29 |
河北医科大学第四医院 |
一种lncRNA NEAT1_1的应用
|
|
DE102021126650A1
(de)
|
2021-10-14 |
2023-04-20 |
Rheinische Friedrich-Wilhelms-Universität Bonn, Körperschaft des öffentlichen Rechts |
Verfahren zur bestimmung der ansprechwahrscheinlichkeit einer malignen erkrankung auf eine behandlung mit einem pharmazeutischen hemmwirkstoff
|
|
CN118369438A
(zh)
|
2021-12-10 |
2024-07-19 |
伯乐实验室有限公司 |
用形态可调节功能化颗粒进行样品处理的组合物、方法和系统
|
|
CN114113265B
(zh)
*
|
2021-12-14 |
2023-08-08 |
郑州轻工业大学 |
一种适配体传感器及其制备方法
|
|
KR20240169002A
(ko)
*
|
2022-03-31 |
2024-12-02 |
코디아 세라퓨틱스 가부시키가이샤 |
이미다조[4,5-b]피리딘 유도체에 의한 고형암 치료를 위한 바이오마커
|
|
TW202515577A
(zh)
*
|
2023-06-27 |
2025-04-16 |
日商大鵬藥品工業股份有限公司 |
患有具有egfr畸變的非小細胞肺癌之個體的治療方法
|
|
KR20250011598A
(ko)
*
|
2023-07-14 |
2025-01-21 |
전남대학교산학협력단 |
암 진단을 위한 시료 처리 방법 및 이를 이용한 암 진단에 대한 정보 제공 방법
|
|
CN117778322B
(zh)
*
|
2023-12-17 |
2025-02-07 |
苏州拓维生物技术有限公司 |
一种对恩杂鲁胺耐药的细胞系的筛选方法及其应用
|