JP2010047597A5 - - Google Patents
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- Publication number
- JP2010047597A5 JP2010047597A5 JP2009242389A JP2009242389A JP2010047597A5 JP 2010047597 A5 JP2010047597 A5 JP 2010047597A5 JP 2009242389 A JP2009242389 A JP 2009242389A JP 2009242389 A JP2009242389 A JP 2009242389A JP 2010047597 A5 JP2010047597 A5 JP 2010047597A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- tumor
- associated antigen
- antibody
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 93
- 108020004707 nucleic acids Proteins 0.000 claims 85
- 102000039446 nucleic acids Human genes 0.000 claims 85
- 206010028980 Neoplasm Diseases 0.000 claims 54
- 239000000427 antigen Substances 0.000 claims 54
- 102000036639 antigens Human genes 0.000 claims 54
- 108091007433 antigens Proteins 0.000 claims 54
- 239000008194 pharmaceutical composition Substances 0.000 claims 21
- 239000003795 chemical substances by application Substances 0.000 claims 17
- 238000000034 method Methods 0.000 claims 16
- 201000010099 disease Diseases 0.000 claims 10
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 9
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 8
- 230000000295 complement effect Effects 0.000 claims 8
- 238000001514 detection method Methods 0.000 claims 6
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 230000002159 abnormal effect Effects 0.000 claims 4
- 239000000032 diagnostic agent Substances 0.000 claims 4
- 229940039227 diagnostic agent Drugs 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 231100000433 cytotoxic Toxicity 0.000 claims 3
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 3
- 230000001472 cytotoxic effect Effects 0.000 claims 3
- 210000002443 helper t lymphocyte Anatomy 0.000 claims 3
- 238000012544 monitoring process Methods 0.000 claims 3
- 230000001613 neoplastic effect Effects 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 229920001184 polypeptide Polymers 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 239000000523 sample Substances 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- 102000004127 Cytokines Human genes 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 2
- 210000001744 T-lymphocyte Anatomy 0.000 claims 2
- 230000000692 anti-sense effect Effects 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 239000002131 composite material Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 206010027476 Metastases Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 210000000612 antigen-presenting cell Anatomy 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 201000008275 breast carcinoma Diseases 0.000 claims 1
- 230000030833 cell death Effects 0.000 claims 1
- 210000000170 cell membrane Anatomy 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 208000019065 cervical carcinoma Diseases 0.000 claims 1
- 230000001461 cytolytic effect Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000037841 lung tumor Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 230000009401 metastasis Effects 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 208000023958 prostate neoplasm Diseases 0.000 claims 1
- 230000028327 secretion Effects 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 230000001875 tumorinhibitory effect Effects 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10211088A DE10211088A1 (de) | 2002-03-13 | 2002-03-13 | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003574831A Division JP4963778B2 (ja) | 2002-03-13 | 2003-03-12 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012213517A Division JP5711711B2 (ja) | 2002-03-13 | 2012-09-27 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010047597A JP2010047597A (ja) | 2010-03-04 |
| JP2010047597A5 true JP2010047597A5 (cg-RX-API-DMAC7.html) | 2011-01-20 |
Family
ID=27771250
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003574831A Expired - Fee Related JP4963778B2 (ja) | 2002-03-13 | 2003-03-12 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
| JP2009242389A Pending JP2010047597A (ja) | 2002-03-13 | 2009-10-21 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
| JP2012213517A Expired - Lifetime JP5711711B2 (ja) | 2002-03-13 | 2012-09-27 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
| JP2012238202A Expired - Lifetime JP5756073B2 (ja) | 2002-03-13 | 2012-10-29 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
| JP2013041406A Expired - Lifetime JP5793158B2 (ja) | 2002-03-13 | 2013-03-04 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003574831A Expired - Fee Related JP4963778B2 (ja) | 2002-03-13 | 2003-03-12 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012213517A Expired - Lifetime JP5711711B2 (ja) | 2002-03-13 | 2012-09-27 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
| JP2012238202A Expired - Lifetime JP5756073B2 (ja) | 2002-03-13 | 2012-10-29 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
| JP2013041406A Expired - Lifetime JP5793158B2 (ja) | 2002-03-13 | 2013-03-04 | 腫瘍において示差的に発現される遺伝子産物およびこの使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (8) | US7429461B2 (cg-RX-API-DMAC7.html) |
| EP (18) | EP2311862A3 (cg-RX-API-DMAC7.html) |
| JP (5) | JP4963778B2 (cg-RX-API-DMAC7.html) |
| KR (4) | KR20110026529A (cg-RX-API-DMAC7.html) |
| CN (4) | CN103251952B (cg-RX-API-DMAC7.html) |
| AU (2) | AU2003219045B2 (cg-RX-API-DMAC7.html) |
| CA (3) | CA2478413C (cg-RX-API-DMAC7.html) |
| DE (1) | DE10211088A1 (cg-RX-API-DMAC7.html) |
| ES (3) | ES2559079T3 (cg-RX-API-DMAC7.html) |
| IL (4) | IL163900A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04008867A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ535146A (cg-RX-API-DMAC7.html) |
| PL (1) | PL215160B1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003076631A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10211088A1 (de) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| CA2496272A1 (en) * | 2002-08-20 | 2004-03-04 | Millennium Pharmaceuticals, Inc. | Integrin b6 markers for compositions, kits, and methods for identification, assessment, prevention and therapy of cervical cancer |
| DE10341812A1 (de) | 2003-09-10 | 2005-04-07 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| DE10344799A1 (de) | 2003-09-26 | 2005-04-14 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| AU2015201737B2 (en) * | 2003-09-26 | 2016-09-15 | Biontech Ag | Identification of tumour-associated cell surface antigens for diagnosis and therapy |
| DE102004023187A1 (de) * | 2004-05-11 | 2005-12-01 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| WO2006073183A1 (ja) * | 2005-01-07 | 2006-07-13 | Riken | 一塩基多型を用いた炎症性疾患の判定方法 |
| DE102005013846A1 (de) * | 2005-03-24 | 2006-10-05 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| EP2083852B1 (en) * | 2006-10-04 | 2014-12-10 | Dana-Farber Cancer Institute, Inc. | Tumor immunity |
| EP2108701A1 (en) * | 2008-04-10 | 2009-10-14 | Ganymed Pharmaceuticals AG | Methods involving MS4A12 and agents targeting MS4A12 for therapy, diagnosis and testing |
| WO2015075939A1 (ja) | 2013-11-21 | 2015-05-28 | Ｒｅｐｅｒｔｏｉｒｅ Ｇｅｎｅｓｉｓ株式会社 | Ｔ細胞受容体およびｂ細胞受容体レパトアの解析システムならびにその治療および診断への利用 |
| WO2015140331A2 (en) | 2014-03-21 | 2015-09-24 | Haldor Topsøe A/S | Gasket free grid modules for catalyst support and a modular system hereof |
| HUE067123T2 (hu) | 2014-12-09 | 2024-10-28 | Regeneron Pharma | Humanizált differenciációs klaszter 274 génnel rendelkezõ nem humán állatok |
| EP3389630B1 (en) | 2015-12-16 | 2023-11-08 | Gritstone bio, Inc. | Neoantigen identification, manufacture, and use |
| JP7227237B2 (ja) | 2017-10-10 | 2023-02-21 | グリットストーン バイオ インコーポレイテッド | ホットスポットを利用した新生抗原の特定 |
| CN111630602A (zh) | 2017-11-22 | 2020-09-04 | 磨石肿瘤生物技术公司 | 减少新抗原的接合表位呈递 |
| CN110734925B (zh) * | 2018-07-20 | 2023-04-07 | 上海市免疫学研究所 | 一种粒细胞或单核细胞标记系统及其标记方法和应用 |
| CN115298328A (zh) * | 2020-01-09 | 2022-11-04 | 德卡生物科学公司 | 使用遗传标记、snp和/或indel确定il-10治疗反应性的方法 |
| WO2024002537A1 (en) | 2022-06-30 | 2024-01-04 | Kmc Kartoffelmelcentralen Amba | Starch based gelatine replacement products |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8192987A (en) * | 1986-12-01 | 1988-06-16 | Northwestern University | Human ldh-c4 cdna sequences encoding antigenic regions |
| US6020145A (en) * | 1989-06-30 | 2000-02-01 | Bristol-Myers Squibb Company | Methods for determining the presence of carcinoma using the antigen binding region of monoclonal antibody BR96 |
| GB9019812D0 (en) | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
| US5677139A (en) | 1995-04-21 | 1997-10-14 | President And Fellows Of Harvard College | In vitro differentiation of CD34+ progenitor cells into T lymphocytes |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| US5990299A (en) * | 1995-08-14 | 1999-11-23 | Icn Pharmaceuticals, Inc. | Control of CD44 gene expression for therapeutic use |
| WO1997026001A1 (en) * | 1996-01-16 | 1997-07-24 | Northwestern University | Proteins and peptides for contraceptive vaccines and fertility diagnosis |
| US5840839A (en) * | 1996-02-09 | 1998-11-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Alternative open reading frame DNA of a normal gene and a novel human cancer antigen encoded therein |
| CA2320427A1 (en) * | 1998-02-12 | 1999-08-19 | Incyte Pharmaceuticals, Inc. | Human receptor proteins |
| DE69929785T2 (de) * | 1998-05-21 | 2006-07-20 | Diadexus, Inc., South San Francisco | Verfahren zur Diagnose, Erkennung, und Einstufung von Dickdarmkrebs |
| US6440663B1 (en) * | 1998-10-05 | 2002-08-27 | Ludwig Institute For Cancer Research | Renal cancer associated antigens and uses therefor |
| WO2001009316A1 (en) * | 1999-07-29 | 2001-02-08 | Helix Research Institute | Novel genes encoding protein kinase/protein phosphatase |
| WO2001009315A1 (en) * | 1999-07-29 | 2001-02-08 | Helix Research Institute | Novel gene participating in the maintenance of smooth muscle cell differentiation |
| DE19936563A1 (de) * | 1999-08-04 | 2001-02-08 | Boehringer Ingelheim Int | Tumorassoziiertes Antigen |
| EP1265582A2 (en) * | 1999-09-29 | 2002-12-18 | Human Genome Sciences, Inc. | Colon and colon cancer associated polynucleotides and polypeptides |
| US7442776B2 (en) | 1999-10-08 | 2008-10-28 | Young David S F | Cancerous disease modifying antibodies |
| WO2001051628A2 (en) * | 2000-01-14 | 2001-07-19 | Millennium Pharmaceuticals, Inc. | Genes compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| AU2001236589A1 (en) * | 2000-02-04 | 2001-08-14 | Aeomica, Inc. | Methods and apparatus for high-throughput detection and characterization of alternatively spliced genes |
| WO2001060860A2 (en) * | 2000-02-17 | 2001-08-23 | Millennium Predictive Medicine, Inc. | Genes differentially expressed in human prostate cancer and their use |
| AU6802801A (en) * | 2000-03-01 | 2001-09-24 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| JP2004528805A (ja) * | 2000-07-28 | 2004-09-24 | インサイト・ゲノミックス・インコーポレイテッド | タンパク質ホスファターゼ |
| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| WO2002059271A2 (en) * | 2001-01-25 | 2002-08-01 | Gene Logic, Inc. | Gene expression profiles in breast tissue |
| AU2002303219A1 (en) | 2001-03-30 | 2002-10-15 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of cancer |
| US20040058341A1 (en) * | 2001-07-26 | 2004-03-25 | Y.Tom Tang | Protein phosphatases |
| KR101008758B1 (ko) | 2001-09-18 | 2011-01-14 | 제넨테크, 인크. | 종양의 진단 및 치료를 위한 방법 및 이를 위한 조성물 |
| DE10211088A1 (de) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| JP5565375B2 (ja) | 2011-05-12 | 2014-08-06 | 三菱電機株式会社 | 入退室管理装置 |
-
2002
- 2002-03-13 DE DE10211088A patent/DE10211088A1/de not_active Withdrawn
-
2003
- 2003-03-12 EP EP10010637A patent/EP2311862A3/de not_active Withdrawn
- 2003-03-12 EP EP10010627A patent/EP2287181A3/de not_active Ceased
- 2003-03-12 EP EP10010632A patent/EP2277907A3/de not_active Withdrawn
- 2003-03-12 CA CA2478413A patent/CA2478413C/en not_active Expired - Lifetime
- 2003-03-12 EP EP10010625A patent/EP2277903A3/de not_active Withdrawn
- 2003-03-12 CN CN201310025680.8A patent/CN103251952B/zh not_active Expired - Lifetime
- 2003-03-12 KR KR1020117004206A patent/KR20110026529A/ko not_active Ceased
- 2003-03-12 KR KR1020047014321A patent/KR101261887B1/ko not_active Expired - Lifetime
- 2003-03-12 AU AU2003219045A patent/AU2003219045B2/en not_active Expired
- 2003-03-12 EP EP10010623A patent/EP2277901A3/de not_active Withdrawn
- 2003-03-12 CN CN201510846314.8A patent/CN105396144B/zh not_active Expired - Lifetime
- 2003-03-12 EP EP10010630A patent/EP2277905A3/de not_active Withdrawn
- 2003-03-12 EP EP10010635A patent/EP2314611A3/de not_active Withdrawn
- 2003-03-12 EP EP10010636A patent/EP2311861A3/de not_active Withdrawn
- 2003-03-12 EP EP10010639A patent/EP2332973A3/de not_active Withdrawn
- 2003-03-12 EP EP10010634.3A patent/EP2314610B1/de not_active Expired - Lifetime
- 2003-03-12 EP EP10010629.3A patent/EP2289910B1/de not_active Expired - Lifetime
- 2003-03-12 NZ NZ535146A patent/NZ535146A/en not_active IP Right Cessation
- 2003-03-12 US US10/506,443 patent/US7429461B2/en not_active Expired - Lifetime
- 2003-03-12 EP EP10010624A patent/EP2277902A3/de not_active Withdrawn
- 2003-03-12 PL PL373384A patent/PL215160B1/pl unknown
- 2003-03-12 EP EP10010633.5A patent/EP2311860B1/de not_active Expired - Lifetime
- 2003-03-12 KR KR1020117024468A patent/KR20110117735A/ko not_active Abandoned
- 2003-03-12 ES ES03714811.1T patent/ES2559079T3/es not_active Expired - Lifetime
- 2003-03-12 CN CNA038074931A patent/CN1646692A/zh active Granted
- 2003-03-12 JP JP2003574831A patent/JP4963778B2/ja not_active Expired - Fee Related
- 2003-03-12 EP EP10010638A patent/EP2314612A3/de not_active Withdrawn
- 2003-03-12 KR KR1020127025908A patent/KR20120127536A/ko not_active Ceased
- 2003-03-12 WO PCT/EP2003/002556 patent/WO2003076631A2/de not_active Ceased
- 2003-03-12 CA CA2813780A patent/CA2813780C/en not_active Expired - Lifetime
- 2003-03-12 IL IL16390003A patent/IL163900A0/xx unknown
- 2003-03-12 ES ES10010628.5T patent/ES2688186T3/es not_active Expired - Lifetime
- 2003-03-12 EP EP10010628.5A patent/EP2287182B1/de not_active Expired - Lifetime
- 2003-03-12 CA CA3035543A patent/CA3035543C/en not_active Expired - Lifetime
- 2003-03-12 CN CN03807493.1A patent/CN1646692B/zh not_active Expired - Lifetime
- 2003-03-12 EP EP03714811.1A patent/EP1483389B1/de not_active Expired - Lifetime
- 2003-03-12 EP EP10010626A patent/EP2277904A3/de not_active Withdrawn
- 2003-03-12 ES ES10010629.3T patent/ES2685053T3/es not_active Expired - Lifetime
- 2003-03-12 MX MXPA04008867A patent/MXPA04008867A/es active IP Right Grant
- 2003-03-12 EP EP10010631A patent/EP2277906A3/de not_active Withdrawn
-
2004
- 2004-09-02 IL IL163900A patent/IL163900A/en active IP Right Grant
-
2008
- 2008-08-25 US US12/197,960 patent/US8716455B2/en not_active Expired - Lifetime
- 2008-08-25 US US12/197,956 patent/US20090081214A1/en not_active Abandoned
- 2008-12-16 AU AU2008258158A patent/AU2008258158A1/en not_active Abandoned
-
2009
- 2009-10-21 JP JP2009242389A patent/JP2010047597A/ja active Pending
-
2011
- 2011-07-18 US US13/184,719 patent/US8551490B2/en not_active Expired - Lifetime
-
2012
- 2012-09-27 JP JP2012213517A patent/JP5711711B2/ja not_active Expired - Lifetime
- 2012-10-29 JP JP2012238202A patent/JP5756073B2/ja not_active Expired - Lifetime
-
2013
- 2013-03-04 JP JP2013041406A patent/JP5793158B2/ja not_active Expired - Lifetime
- 2013-03-12 US US13/796,094 patent/US9637794B2/en not_active Expired - Fee Related
-
2014
- 2014-05-02 US US14/268,160 patent/US9453260B2/en not_active Expired - Fee Related
- 2014-10-07 IL IL235085A patent/IL235085A/en active IP Right Grant
-
2015
- 2015-07-10 US US14/796,509 patent/US20160002738A1/en not_active Abandoned
-
2016
- 2016-03-14 IL IL244596A patent/IL244596A0/en unknown
- 2016-09-22 US US15/273,378 patent/US20170101479A1/en not_active Abandoned
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