JP2010019854A5 - - Google Patents
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- Publication number
- JP2010019854A5 JP2010019854A5 JP2009239298A JP2009239298A JP2010019854A5 JP 2010019854 A5 JP2010019854 A5 JP 2010019854A5 JP 2009239298 A JP2009239298 A JP 2009239298A JP 2009239298 A JP2009239298 A JP 2009239298A JP 2010019854 A5 JP2010019854 A5 JP 2010019854A5
- Authority
- JP
- Japan
- Prior art keywords
- following structure
- acridinium compound
- acridinium
- compound
- following
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 acridinium compound Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/898,381 US6664043B2 (en) | 2001-07-03 | 2001-07-03 | Acridinium ester labels having hydrophilic modifiers |
| US09/898381 | 2001-07-03 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002185836A Division JP4467869B2 (ja) | 2001-07-03 | 2002-06-26 | 親水性修飾剤を有するアクリジニウムエステル標識 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010019854A JP2010019854A (ja) | 2010-01-28 |
| JP2010019854A5 true JP2010019854A5 (https=) | 2010-03-11 |
| JP4913195B2 JP4913195B2 (ja) | 2012-04-11 |
Family
ID=25409366
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002185836A Expired - Lifetime JP4467869B2 (ja) | 2001-07-03 | 2002-06-26 | 親水性修飾剤を有するアクリジニウムエステル標識 |
| JP2009239298A Expired - Lifetime JP4913195B2 (ja) | 2001-07-03 | 2009-10-16 | 親水性修飾剤を有するアクリジニウムエステル標識 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002185836A Expired - Lifetime JP4467869B2 (ja) | 2001-07-03 | 2002-06-26 | 親水性修飾剤を有するアクリジニウムエステル標識 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6664043B2 (https=) |
| EP (1) | EP1273917B1 (https=) |
| JP (2) | JP4467869B2 (https=) |
| AU (1) | AU782559B2 (https=) |
| CA (1) | CA2387466A1 (https=) |
| ES (1) | ES2486815T3 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6653456B2 (en) * | 2001-07-31 | 2003-11-25 | Roche Diagnostics Corporation | Site-specific aminoglycoside derivatives and their use in immunodiagnostic assays |
| EP1539702B1 (en) * | 2002-08-20 | 2012-04-11 | Quest Diagnostics Investments Incorporated | Hydrophilic chemiluminescent acridinium labeling reagents |
| US7309615B2 (en) * | 2002-09-27 | 2007-12-18 | Siemens Medical Solutions Diagnostic | High quantum yield acridinium compounds and their uses in improving assay sensitivity |
| CN101384272B (zh) | 2005-12-20 | 2013-05-01 | 杜克大学 | 用于递送具有增强的药理性质的活性剂的方法和组合物 |
| US8106154B2 (en) * | 2007-01-31 | 2012-01-31 | Affymax, Inc. | Nitrogen-based linkers for attaching modifying groups to polypeptides and other macromolecules |
| JP4887319B2 (ja) | 2008-03-17 | 2012-02-29 | 株式会社日立ハイテクノロジーズ | 自動分析装置、及び光電子増倍管を用いた分析システム |
| JP5209705B2 (ja) | 2008-05-08 | 2013-06-12 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| JP5124498B2 (ja) | 2009-01-30 | 2013-01-23 | 株式会社日立ハイテクノロジーズ | 自動分析装置 |
| CN105153115B (zh) | 2009-11-16 | 2021-08-03 | 西门子医疗保健诊断公司 | 含两性离子的吖啶鎓化合物 |
| US9512080B2 (en) | 2012-07-10 | 2016-12-06 | Siemens Healthcare Diagnostics Inc. | Synthesis of acridinium compounds by N-alkylation of acridans |
| KR102227919B1 (ko) * | 2012-11-30 | 2021-03-15 | 가부시키가이샤 도우사 고가쿠 겐큐쇼 | 당쇄 부가 링커, 당쇄 부가 링커와 생리 활성 물질을 포함하는 화합물 또는 그 염, 및 그것들의 제조 방법 |
| FR3000551B1 (fr) * | 2012-12-27 | 2015-06-26 | Biomerieux Sa | Derives de folate, particulierement utiles dans le cadre du dosage de folate(s) |
| JP6494599B2 (ja) | 2013-05-14 | 2019-04-03 | シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドＳｉｅｍｅｎｓ Ｈｅａｌｔｈｃａｒｅ Ｄｉａｇｎｏｓｔｉｃｓ Ｉｎｃ． | 分解可能なカチオン界面活性剤および化学発光を増強するためのその利用 |
| ES2716395T3 (es) | 2013-07-08 | 2019-06-12 | Siemens Healthcare Diagnostics Inc | Esteres de acridinio hidrófilos de alto rendimiento cuántico con estabilidad mejorada y emisión rápida de luz |
| ES2906117T3 (es) * | 2017-02-23 | 2022-04-13 | Siemens Healthcare Diagnostics Inc | Conjugados de androstenodiona quimioluminiscente |
| US11203573B2 (en) | 2018-06-25 | 2021-12-21 | Siemens Healthcare Diagnostics Inc. | N-alkylation of acridans |
| CN109535062B (zh) * | 2019-01-10 | 2021-03-23 | 中北大学 | 一种降冰片烯类两性离子单体及其制备方法 |
| CN110850077A (zh) * | 2019-11-06 | 2020-02-28 | 迪瑞医疗科技股份有限公司 | 妥布霉素化学发光检测试剂盒及其制备方法 |
| CN112920399A (zh) * | 2019-12-05 | 2021-06-08 | 广东菲鹏生物有限公司 | 吖啶化合物标记类固醇激素衍生物及其制备方法和应用 |
| CN112684163B (zh) * | 2021-01-29 | 2022-08-09 | 安邦（厦门）生物科技有限公司 | 一种吖啶类化合物标记原料工作液及制备方法 |
| CN117769588B (zh) | 2021-07-29 | 2025-02-21 | 欧蒙医学实验诊断股份公司 | 增强化学发光信号的方法和试剂 |
| CN116284978B (zh) * | 2022-12-16 | 2024-09-20 | 厦门为正生物科技股份有限公司 | 一种荧光微球及其制备方法与应用 |
| WO2024137034A1 (en) * | 2022-12-21 | 2024-06-27 | Siemens Healthcare Diagnostics Inc. | Cyclosporine-acridinium esters and methods of production and use thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE40572T1 (de) * | 1985-01-10 | 1989-02-15 | Molecular Diagnostics Inc | Photochemisches verfahren zum markieren von nucleinsaeuren zum nachweis in hybridisationsproben. |
| US5656426A (en) * | 1988-08-01 | 1997-08-12 | Chiron Diagnostics Corporation | Functionaized hydrophilic acridinium esters |
| JPH0286567A (ja) * | 1988-09-21 | 1990-03-27 | Ricoh Co Ltd | シート後処理制御装置 |
| CA1339491C (en) * | 1988-09-26 | 1997-10-07 | Say-Jong Law | Nucleophilic polysubstituted aryl acridinium ester and uses thereof |
| US5663074A (en) * | 1988-09-26 | 1997-09-02 | Chiron Diagnostics Corporation | Nucleophilic polysubstituted aryl acridinium ester conjugates and syntheses thereof |
| DE4004296A1 (de) * | 1990-02-13 | 1991-08-14 | Hoechst Ag | Verbesserte markierte haptene, verfahren zu deren herstellung sowie verwendung dieser markierten haptene in immunoassays |
| DE4444002A1 (de) * | 1994-12-10 | 1996-06-13 | Behringwerke Ag | Immunoassays für Haptene und hierfür verwendbare Haptentracer-Antikörper-Komplexe sowie Verfahren zur Herstellung derselben |
| US6165800A (en) * | 1997-05-30 | 2000-12-26 | Bayer Corporation | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays |
| WO2000031543A1 (en) * | 1998-11-25 | 2000-06-02 | Bayer Corporation | Measurement of hydride using chemiluminescent acridinium compounds |
| US6187566B1 (en) * | 1999-03-09 | 2001-02-13 | Applied Gene Technologies, Inc. | Method of labeling a nucleic acid amplicon with simultaneous contamination prevention |
| US6242188B1 (en) * | 1999-07-30 | 2001-06-05 | Applied Gene Technologies, Inc. | Sample processing to release nucleic acids for direct detection |
| ATE291096T1 (de) * | 1999-07-30 | 2005-04-15 | Bayer Ag | Chemilumineszenz-substrate von hydrolytischen enzymen wie phosphatasen |
-
2001
- 2001-07-03 US US09/898,381 patent/US6664043B2/en not_active Expired - Lifetime
-
2002
- 2002-05-24 CA CA002387466A patent/CA2387466A1/en not_active Abandoned
- 2002-05-31 AU AU45736/02A patent/AU782559B2/en not_active Ceased
- 2002-06-21 EP EP02013902.8A patent/EP1273917B1/en not_active Expired - Lifetime
- 2002-06-21 ES ES02013902.8T patent/ES2486815T3/es not_active Expired - Lifetime
- 2002-06-26 JP JP2002185836A patent/JP4467869B2/ja not_active Expired - Lifetime
-
2009
- 2009-10-16 JP JP2009239298A patent/JP4913195B2/ja not_active Expired - Lifetime