JP2009545534A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009545534A5 JP2009545534A5 JP2009522067A JP2009522067A JP2009545534A5 JP 2009545534 A5 JP2009545534 A5 JP 2009545534A5 JP 2009522067 A JP2009522067 A JP 2009522067A JP 2009522067 A JP2009522067 A JP 2009522067A JP 2009545534 A5 JP2009545534 A5 JP 2009545534A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- aryl
- compound according
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83542806P | 2006-08-04 | 2006-08-04 | |
| US60/835,428 | 2006-08-04 | ||
| PCT/CA2007/001357 WO2008014613A1 (en) | 2006-08-04 | 2007-08-01 | Multifunctional bioactive compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009545534A JP2009545534A (ja) | 2009-12-24 |
| JP2009545534A5 true JP2009545534A5 (enExample) | 2010-02-12 |
| JP5357022B2 JP5357022B2 (ja) | 2013-12-04 |
Family
ID=38996830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009522067A Expired - Fee Related JP5357022B2 (ja) | 2006-08-04 | 2007-08-01 | 多機能生物活性化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8637521B2 (enExample) |
| EP (1) | EP2046778B1 (enExample) |
| JP (1) | JP5357022B2 (enExample) |
| CN (1) | CN101511823B (enExample) |
| AU (1) | AU2007280995C1 (enExample) |
| BR (1) | BRPI0714616A2 (enExample) |
| CA (1) | CA2659875C (enExample) |
| EA (1) | EA018548B1 (enExample) |
| MX (1) | MX2009001351A (enExample) |
| WO (1) | WO2008014613A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| ATE385193T1 (de) | 2002-03-20 | 2008-02-15 | Mannkind Corp | Inhalationsgerät |
| DK1786784T3 (da) | 2004-08-20 | 2011-02-14 | Mannkind Corp | Katalyse af diketopiperazinsyntese |
| BRPI0514293B1 (pt) | 2004-08-23 | 2022-07-19 | Mannkind Corporation | Sistema microparticulado para distribuição de droga |
| DK1928423T3 (en) | 2005-09-14 | 2016-02-29 | Mannkind Corp | A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces |
| CA2643464C (en) | 2006-02-22 | 2018-09-04 | Mannkind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| CA2571645A1 (en) * | 2006-12-19 | 2008-06-19 | Apotex Technologies Inc. | Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture |
| WO2011163272A1 (en) | 2010-06-21 | 2011-12-29 | Mannkind Corporation | Dry powder drug delivery system and methods |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CN106039494B (zh) | 2008-06-13 | 2019-12-24 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| BRPI0914308B8 (pt) | 2008-06-20 | 2021-06-22 | Mannkind Corp | sistema de inalação |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| CA2748490C (en) * | 2008-12-29 | 2016-10-04 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| CA2749163A1 (en) | 2009-01-14 | 2010-07-22 | The Salk Institute For Biological Studies | Methods for screening and compounds that protect against amyloid diseases |
| WO2010105094A1 (en) | 2009-03-11 | 2010-09-16 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
| MY186975A (en) | 2009-06-12 | 2021-08-26 | Mannkind Corp | Diketopiperazine microparticles with defined specific surface areas |
| AU2010282169A1 (en) | 2009-08-10 | 2012-03-08 | Immunotech Developments Inc. | Vaccine having a peptide adjuvant for eliciting a specific immune response to treat viral infection and other conditions |
| EP2496295A1 (en) | 2009-11-03 | 2012-09-12 | MannKind Corporation | An apparatus and method for simulating inhalation efforts |
| MY180552A (en) | 2011-04-01 | 2020-12-02 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
| PL2812372T3 (pl) | 2012-02-09 | 2018-12-31 | Novus International Inc. | Cykliczne dimery zawierające heteroatom |
| WO2013166110A1 (en) * | 2012-05-02 | 2013-11-07 | Yale University | Tlr-agonist-conjugated antibody recruiting molecules (tlr_arms) |
| DK2872205T3 (en) | 2012-07-12 | 2017-02-27 | Mannkind Corp | DRY POWDER FORMAL ADMINISTRATION SYSTEM |
| WO2014011857A1 (en) | 2012-07-12 | 2014-01-16 | Novus International Inc. | Matrix and layer compositions for protection of bioactives |
| WO2014016787A2 (en) | 2012-07-24 | 2014-01-30 | Pharma Bio Llc | Peptide-based compounds and uses thereof to treat beta-amyloid accumulation |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| KR102391750B1 (ko) | 2013-03-15 | 2022-04-28 | 맨카인드 코포레이션 | 미세결정성 디케토피페라진 조성물 및 방법 |
| EP3021834A1 (en) | 2013-07-18 | 2016-05-25 | MannKind Corporation | Heat-stable dry powder pharmaceutical compositions and methods |
| US11446127B2 (en) | 2013-08-05 | 2022-09-20 | Mannkind Corporation | Insufflation apparatus and methods |
| WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| CN110054619A (zh) * | 2018-01-18 | 2019-07-26 | 西北农林科技大学 | 新型二酮哌嗪类组蛋白去乙酰化酶抑制剂 |
| WO2020041965A1 (en) * | 2018-08-28 | 2020-03-05 | Lingdong Technology (Beijing) Co., Ltd | Self-driving systems with inventory holder |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4006261A (en) * | 1973-09-28 | 1977-02-01 | Firmenich S.A. | Flavoring with mixtures of theobromine and cyclic dipeptides |
| US4289759A (en) * | 1980-06-23 | 1981-09-15 | Ortho Pharmaceutical Corporation | Immunoregulatory diketopiperazine compounds |
| US4331595A (en) * | 1980-06-23 | 1982-05-25 | Ortho Pharmaceutical Corporation | Immunoregulatory diketopiperazine compounds |
| GB8427735D0 (en) * | 1984-11-02 | 1984-12-12 | Fujisawa Pharmaceutical Co | Piperazine compound |
| DE3909379A1 (de) * | 1989-03-22 | 1990-09-27 | Cassella Ag | Thienylpiperazine, verfahren zu ihrer herstellung, ihre verwendung sowie diese enthaltende arzneimittel und deren herstellung |
| US6331318B1 (en) | 1994-09-30 | 2001-12-18 | Emisphere Technologies Inc. | Carbon-substituted diketopiperazine delivery systems |
| US5693338A (en) * | 1994-09-29 | 1997-12-02 | Emisphere Technologies, Inc. | Diketopiperazine-based delivery systems |
| FR2677361A1 (fr) | 1991-06-04 | 1992-12-11 | Adir | Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| ATE188219T1 (de) * | 1991-10-28 | 2000-01-15 | Cytran Ltd | Pharmazeutische dipeptid zusammensetzungen und verwendungsmethoden. |
| US5352461A (en) * | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
| FR2722787B1 (fr) * | 1994-07-21 | 1996-10-11 | Univ Claude Bernard Lyon | Composes a activite anthelminthique: dicetopiperazines, precurseurs et analogues |
| US6103699A (en) | 1996-06-07 | 2000-08-15 | Immunotech Developments Inc. | Peptide, a method for its preparation and a pharmaceutical composition containing the peptide |
| US6060452A (en) * | 1996-03-13 | 2000-05-09 | Cytran, Inc. | Analogs of L-Glu-L-Trp having pharmacological activity |
| US5932579A (en) * | 1996-06-18 | 1999-08-03 | Affymax Technologies N.V. | Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use |
| JPH10226615A (ja) * | 1997-02-18 | 1998-08-25 | Pola Chem Ind Inc | アスパラギン酸フェニルアラニン環状ジペプタイド誘導体を含有する組成物 |
| US7026322B2 (en) | 1998-11-12 | 2006-04-11 | Nereus Pharmaceuticals, Inc. | Phenylahistin and the phenylahistin analogs, a new class of anti-tumor compounds |
| DE19937721A1 (de) * | 1999-08-10 | 2001-02-15 | Max Planck Gesellschaft | Neue Diketopiperazine |
| US6974478B2 (en) | 1999-10-22 | 2005-12-13 | Archus Orthopedics, Inc. | Prostheses, systems and methods for replacement of natural facet joints with artificial facet joint surfaces |
| JP2001247566A (ja) * | 2000-03-03 | 2001-09-11 | Marine Biotechnol Inst Co Ltd | 新規抗カビ活性物質およびその製造法 |
| PT1311269E (pt) * | 2000-08-04 | 2012-05-10 | Dmi Biosciences Inc | Método de utilização de dicetopiperazinas e composição que contém as mesmas |
| US20030171379A1 (en) * | 2001-12-28 | 2003-09-11 | Jacobs Robert S. | Methods of treating, preventing, or inhibiting inflammation with Mactanamide compounds |
| JP3846409B2 (ja) | 2002-02-15 | 2006-11-15 | 株式会社村田製作所 | 弾性表面波装置、通信装置 |
| KR20120101164A (ko) | 2003-05-15 | 2012-09-12 | 디엠아이 바이오사이언시스, 인크 | Ｔ-세포 매개성 질환의 치료 방법 |
| BRPI0514293B1 (pt) * | 2004-08-23 | 2022-07-19 | Mannkind Corporation | Sistema microparticulado para distribuição de droga |
-
2007
- 2007-08-01 MX MX2009001351A patent/MX2009001351A/es active IP Right Grant
- 2007-08-01 BR BRPI0714616-7A2A patent/BRPI0714616A2/pt not_active Application Discontinuation
- 2007-08-01 CN CN200780033302.7A patent/CN101511823B/zh not_active Expired - Fee Related
- 2007-08-01 CA CA 2659875 patent/CA2659875C/en active Active
- 2007-08-01 JP JP2009522067A patent/JP5357022B2/ja not_active Expired - Fee Related
- 2007-08-01 EP EP07785022.0A patent/EP2046778B1/en active Active
- 2007-08-01 WO PCT/CA2007/001357 patent/WO2008014613A1/en not_active Ceased
- 2007-08-01 EA EA200970178A patent/EA018548B1/ru not_active IP Right Cessation
- 2007-08-01 AU AU2007280995A patent/AU2007280995C1/en not_active Ceased
- 2007-08-01 US US12/376,138 patent/US8637521B2/en active Active
-
2013
- 2013-12-19 US US14/134,418 patent/US9108931B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2009545534A5 (enExample) | ||
| TWI511972B (zh) | 蛋白酶體抑制劑 | |
| US10208037B2 (en) | Toll-like receptor-7 and -8 modulatory 1H imidazoquinoline derived compounds | |
| JP2020063241A5 (enExample) | ||
| JP2013523896A5 (enExample) | ||
| JP2009538348A5 (enExample) | ||
| BRPI0721905A2 (pt) | Inibidores de proteassoma | |
| JP6223995B2 (ja) | カンプトテシン類と抗癌効果増強剤の結合した高分子化合物及びその用途 | |
| JP2013500304A5 (enExample) | ||
| CN104557914A (zh) | 3-脱氮瓶菌素衍生物 | |
| JP2011523645A5 (enExample) | ||
| KR100199524B1 (ko) | 엔-헤테로아릴-푸린-6-아민 및 이의 제조방법 | |
| RU2016122731A (ru) | Функционализированные и замещенные индолы в качестве противораковых агентов | |
| JP2014532728A5 (enExample) | ||
| ES2746105T3 (es) | Profármacos de 5-aza-pirimidina sililada útiles para tratar el cáncer | |
| US20080027094A1 (en) | Tropane Compounds and Pharmaceutical Compositions Comprising the Same as an Active Ingredient | |
| CN111491937A (zh) | 作为精氨酸酶抑制剂的杂环化合物 | |
| JP2005532269A5 (enExample) | ||
| JP2024540030A (ja) | 修飾インドール化合物 | |
| CN102961387B (zh) | 蛋白酶体抑制剂 | |
| US20230382886A1 (en) | Conjugated tlr7 and nod2 agonists | |
| WO2022022360A1 (zh) | 聚乙二醇偶联药物、其制备方法及用途 | |
| KR20220119052A (ko) | 합성 공정 및 중간체 | |
| CN110049768B (zh) | 酚噻嗪衍生物及其使用方法 | |
| JP2010500971A5 (enExample) |