JP2014532728A5 - - Google Patents
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- Publication number
- JP2014532728A5 JP2014532728A5 JP2014540197A JP2014540197A JP2014532728A5 JP 2014532728 A5 JP2014532728 A5 JP 2014532728A5 JP 2014540197 A JP2014540197 A JP 2014540197A JP 2014540197 A JP2014540197 A JP 2014540197A JP 2014532728 A5 JP2014532728 A5 JP 2014532728A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- hydrogen
- group
- composition
- opioid agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556693P | 2011-11-07 | 2011-11-07 | |
| US61/556,693 | 2011-11-07 | ||
| PCT/US2012/063725 WO2013070617A1 (en) | 2011-11-07 | 2012-11-06 | Compositions, dosage forms, and coadministration of an opioid agonist compound and an analgesic compound |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018118989A Division JP2018158940A (ja) | 2011-11-07 | 2018-06-22 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014532728A JP2014532728A (ja) | 2014-12-08 |
| JP2014532728A5 true JP2014532728A5 (enExample) | 2015-12-10 |
| JP6593993B2 JP6593993B2 (ja) | 2019-10-23 |
Family
ID=47297432
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014540197A Expired - Fee Related JP6593993B2 (ja) | 2011-11-07 | 2012-11-06 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
| JP2018118989A Withdrawn JP2018158940A (ja) | 2011-11-07 | 2018-06-22 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018118989A Withdrawn JP2018158940A (ja) | 2011-11-07 | 2018-06-22 | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9457024B2 (enExample) |
| EP (1) | EP2776046A1 (enExample) |
| JP (2) | JP6593993B2 (enExample) |
| KR (1) | KR102016305B1 (enExample) |
| CN (1) | CN103906522B (enExample) |
| AU (1) | AU2012336030B2 (enExample) |
| CA (1) | CA2854512A1 (enExample) |
| MX (1) | MX348933B (enExample) |
| WO (1) | WO2013070617A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10512644B2 (en) * | 2007-03-12 | 2019-12-24 | Inheris Pharmaceuticals, Inc. | Oligomer-opioid agonist conjugates |
| AU2012336030B2 (en) | 2011-11-07 | 2017-09-14 | Nektar Therapeutics | Compositions, dosage forms, and coadministration of an opioid agonist compound and an analgesic compound |
| US10525054B2 (en) | 2011-11-07 | 2020-01-07 | Inheris Biopharma, Inc. | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| EP3074379B1 (en) * | 2013-11-27 | 2019-06-26 | Nektar Therapeutics (India) Pvt. Ltd. | Opioid agonists and uses thereof |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| EP3169315B1 (en) | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
| WO2016064873A1 (en) | 2014-10-20 | 2016-04-28 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| CN105111136B (zh) * | 2015-09-16 | 2017-07-04 | 上海皓伯化工科技有限公司 | 一种制备3‑甲基‑1‑苯乙基哌啶‑4‑酮或1‑苯乙基哌啶‑4‑酮的方法 |
| CN107033154B (zh) * | 2016-02-02 | 2020-02-04 | 上海瀚迈生物医药科技有限公司 | 阿片受体拮抗剂缀合物及其应用 |
| CN117003693A (zh) * | 2022-05-05 | 2023-11-07 | 四川大学华西医院 | 一类哌啶衍生物及其制备方法和用途 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2628962A (en) | 1949-10-20 | 1953-02-17 | Mallinckrodt Chemical Works | Method for preparing dihydrocodeinone, dihydromorphinone, and codeinone |
| US2654756A (en) | 1949-10-20 | 1953-10-06 | Mallinckrodt Chemical Works | Process of preparing codeinone, dihydrocodeinone, and dihydromorphinone |
| US2649454A (en) | 1951-08-20 | 1953-08-18 | Univ California | Method for preparing dihydromorphinone, dihydrocodeinone, and dihydropseudocodeinone |
| US2806033A (en) | 1955-08-03 | 1957-09-10 | Lewenstein | Morphine derivative |
| GB971700A (en) * | 1961-02-02 | 1964-09-30 | Boots Pure Drug Co Ltd | Anti-Inflammatory Agents |
| AU661723B2 (en) * | 1991-10-30 | 1995-08-03 | Mcneilab, Inc. | Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug |
| US5672662A (en) | 1995-07-07 | 1997-09-30 | Shearwater Polymers, Inc. | Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications |
| US5840731A (en) * | 1995-08-02 | 1998-11-24 | Virginia Commonwealth University | Pain-alleviating drug composition and method for alleviating pain |
| US6835802B2 (en) | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
| DK2939696T3 (en) * | 2001-10-18 | 2016-05-23 | Nektar Therapeutics | Polymer Conjugates of Opioid Antagonists |
| US7375106B2 (en) | 2002-05-16 | 2008-05-20 | N.V. Organon | Synergistic combination of an opioid analgesic and a NSAID |
| DK1694363T3 (en) | 2003-12-16 | 2014-03-24 | Nektar Therapeutics | Monodisperse PEGylated Naloxole Compositions |
| CN101410095B (zh) | 2006-03-06 | 2015-07-01 | 波曾公司 | 施用组合药物的剂型 |
| EP2019586A4 (en) | 2006-05-03 | 2009-09-02 | Proethic Pharmaceuticals Inc | MEDICATION OF ACUTE PAIN BASED ON FAST DICLOFENAC OPIOID COMBINATIONS |
| JP2010509227A (ja) * | 2006-11-07 | 2010-03-25 | ネクター セラピューティックス エイエル，コーポレイション | オピオイド作動薬およびオピオイド拮抗薬の用量形態および同時投与 |
| EP2134371B1 (en) * | 2007-03-12 | 2015-01-14 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| US8173666B2 (en) | 2007-03-12 | 2012-05-08 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| EP2022778A1 (en) * | 2007-08-07 | 2009-02-11 | Laboratorios del Dr. Esteve S.A. | A crystalline form of (R,R)-tramadol-(S)-naproxene salt |
| AU2009292631A1 (en) | 2008-09-16 | 2010-03-25 | Nektar Therapeutics | Pegylated opioids with low potential for abuse |
| AU2009332963B2 (en) * | 2008-12-31 | 2015-02-05 | Upsher-Smith Laboratories, Llc | Opioid-containing oral pharmaceutical compositions and methods |
| CA2768392C (en) * | 2009-07-21 | 2018-04-17 | Nektar Therapeutics | Oligomer-opioid agonist conjugates |
| SG10201406930UA (en) | 2009-07-27 | 2014-11-27 | Nocicepta Llc | Methods For Treatment Of Pain |
| US8202525B2 (en) * | 2009-12-22 | 2012-06-19 | Pondera Biotechnologies, LLC | Methods and compositions for treating distress dysfunction and enhancing safety and efficacy of specific medications |
| US20130023553A1 (en) | 2010-01-12 | 2013-01-24 | Nektar Therapeutics | Pegylated opioids with low potential for abuse and side effects |
| AU2012336030B2 (en) | 2011-11-07 | 2017-09-14 | Nektar Therapeutics | Compositions, dosage forms, and coadministration of an opioid agonist compound and an analgesic compound |
-
2012
- 2012-11-06 AU AU2012336030A patent/AU2012336030B2/en not_active Ceased
- 2012-11-06 CN CN201280054543.0A patent/CN103906522B/zh not_active Expired - Fee Related
- 2012-11-06 WO PCT/US2012/063725 patent/WO2013070617A1/en not_active Ceased
- 2012-11-06 MX MX2014005571A patent/MX348933B/es active IP Right Grant
- 2012-11-06 KR KR1020147015187A patent/KR102016305B1/ko not_active Expired - Fee Related
- 2012-11-06 EP EP12798075.3A patent/EP2776046A1/en not_active Withdrawn
- 2012-11-06 CA CA2854512A patent/CA2854512A1/en not_active Abandoned
- 2012-11-06 JP JP2014540197A patent/JP6593993B2/ja not_active Expired - Fee Related
- 2012-11-06 US US14/356,486 patent/US9457024B2/en active Active
-
2016
- 2016-09-01 US US15/254,830 patent/US9925182B2/en active Active
-
2018
- 2018-06-22 JP JP2018118989A patent/JP2018158940A/ja not_active Withdrawn
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