JP2011520977A5 - - Google Patents
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- Publication number
- JP2011520977A5 JP2011520977A5 JP2011510691A JP2011510691A JP2011520977A5 JP 2011520977 A5 JP2011520977 A5 JP 2011520977A5 JP 2011510691 A JP2011510691 A JP 2011510691A JP 2011510691 A JP2011510691 A JP 2011510691A JP 2011520977 A5 JP2011520977 A5 JP 2011520977A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- pharmaceutically acceptable
- solvate
- compound
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5477408P | 2008-05-20 | 2008-05-20 | |
| US61/054,774 | 2008-05-20 | ||
| PCT/US2009/044743 WO2009143295A1 (en) | 2008-05-20 | 2009-05-20 | Water-soluble acetaminophen analogs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014049672A Division JP2014111658A (ja) | 2008-05-20 | 2014-03-13 | 水溶性アセトアミノフェン類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520977A JP2011520977A (ja) | 2011-07-21 |
| JP2011520977A5 true JP2011520977A5 (enExample) | 2012-07-05 |
| JP5757864B2 JP5757864B2 (ja) | 2015-08-05 |
Family
ID=41340538
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510691A Expired - Fee Related JP5757864B2 (ja) | 2008-05-20 | 2009-05-20 | 水溶性アセトアミノフェン類似体 |
| JP2014049672A Withdrawn JP2014111658A (ja) | 2008-05-20 | 2014-03-13 | 水溶性アセトアミノフェン類似体 |
| JP2016016971A Expired - Fee Related JP6063072B2 (ja) | 2008-05-20 | 2016-02-01 | 水溶性アセトアミノフェン類似体 |
| JP2016242968A Withdrawn JP2017057217A (ja) | 2008-05-20 | 2016-12-15 | 水溶性アセトアミノフェン類似体 |
| JP2018098716A Withdrawn JP2018135392A (ja) | 2008-05-20 | 2018-05-23 | 水溶性アセトアミノフェン類似体 |
| JP2020074690A Withdrawn JP2020114876A (ja) | 2008-05-20 | 2020-04-20 | 水溶性アセトアミノフェン類似体 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014049672A Withdrawn JP2014111658A (ja) | 2008-05-20 | 2014-03-13 | 水溶性アセトアミノフェン類似体 |
| JP2016016971A Expired - Fee Related JP6063072B2 (ja) | 2008-05-20 | 2016-02-01 | 水溶性アセトアミノフェン類似体 |
| JP2016242968A Withdrawn JP2017057217A (ja) | 2008-05-20 | 2016-12-15 | 水溶性アセトアミノフェン類似体 |
| JP2018098716A Withdrawn JP2018135392A (ja) | 2008-05-20 | 2018-05-23 | 水溶性アセトアミノフェン類似体 |
| JP2020074690A Withdrawn JP2020114876A (ja) | 2008-05-20 | 2020-04-20 | 水溶性アセトアミノフェン類似体 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US20110212926A1 (enExample) |
| EP (1) | EP2291348A4 (enExample) |
| JP (6) | JP5757864B2 (enExample) |
| KR (1) | KR101698028B1 (enExample) |
| CN (2) | CN102149672A (enExample) |
| AU (1) | AU2009249067A1 (enExample) |
| BR (1) | BRPI0912326A2 (enExample) |
| CA (1) | CA2724877C (enExample) |
| IL (1) | IL209382A0 (enExample) |
| MX (1) | MX2010012648A (enExample) |
| RU (1) | RU2010151952A (enExample) |
| WO (1) | WO2009143295A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2009249069A1 (en) | 2008-05-20 | 2009-11-26 | Neurogesx, Inc. | Carbonate prodrugs and methods of using the same |
| AU2009249071A1 (en) | 2008-05-20 | 2009-11-26 | Neurogesx, Inc. | Hepatoprotectant acetaminophen mutual prodrugs |
| JP5757864B2 (ja) | 2008-05-20 | 2015-08-05 | ニューロジェシックス, インコーポレイテッド | 水溶性アセトアミノフェン類似体 |
| EP2177215A1 (en) | 2008-10-17 | 2010-04-21 | Laboratorios Del. Dr. Esteve, S.A. | Co-crystals of tramadol and NSAIDs |
| US9359376B2 (en) * | 2011-04-08 | 2016-06-07 | Sphaera Pharma Pte. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| EP2758133A4 (en) | 2011-09-22 | 2015-05-27 | Acorda Therapeutics Inc | ACETAMINOPHONE CONJUGATES, COMPOSITIONS AND METHOD OF USE THEREOF |
| CA3042642A1 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
| WO2015095391A1 (en) | 2013-12-17 | 2015-06-25 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
| DK3169315T3 (da) | 2014-07-17 | 2020-08-10 | Pharmaceutical Manufacturing Res Services In | Væskefyldt doseringsform til forhindring af misbrug med øjeblikkelig frigivelse |
| CN117164657A (zh) | 2014-08-12 | 2023-12-05 | 莫纳什大学 | 定向淋巴的前药 |
| AU2015336065A1 (en) | 2014-10-20 | 2017-05-04 | Pharmaceutical Manufacturing Research Services, Inc. | Extended release abuse deterrent liquid fill dosage form |
| ES2739536T3 (es) | 2014-10-21 | 2020-01-31 | Abbvie Inc | Profármacos de carbidopa y L-dopa y su uso para tratar la enfermedad de Parkinson |
| EP3265097A4 (en) | 2015-03-03 | 2018-11-07 | Kindred Biosciences Inc. | Compositions and methods for treatment and prevention of pyrexia in horses |
| CN118063537A (zh) | 2015-09-08 | 2024-05-24 | 莫纳什大学 | 定向淋巴的前药 |
| US20190224220A1 (en) * | 2016-04-20 | 2019-07-25 | Abbvie Inc. | Carbidopa and L-Dopa Prodrugs and Methods of Use |
| EP4306524A3 (en) | 2017-08-29 | 2024-09-11 | PureTech LYT, Inc. | Lymphatic system-directing lipid prodrugs |
| US11883497B2 (en) | 2017-08-29 | 2024-01-30 | Puretech Lyt, Inc. | Lymphatic system-directing lipid prodrugs |
| EP3727362A4 (en) | 2017-12-19 | 2021-10-06 | PureTech LYT, Inc. | MYCOPHENOLIC ACID LIPID PRODRUGS AND THEIR USES |
| US11608345B1 (en) | 2017-12-19 | 2023-03-21 | Puretech Lyt, Inc. | Lipid prodrugs of rapamycin and its analogs and uses thereof |
| US11304954B2 (en) | 2017-12-19 | 2022-04-19 | Puretech Lyt, Inc. | Lipid prodrugs of mycophenolic acid and uses thereof |
| KR102928295B1 (ko) | 2018-09-07 | 2026-02-13 | 알.피.쉐러 테크놀러지즈 엘엘씨 | 경화 및 낮은 hlb 계면 활성제(들)의 첨가를 통한 고체 또는 반고체 지질 기반 제형 안정화 |
| TW202031265A (zh) | 2018-11-15 | 2020-09-01 | 美商艾伯維有限公司 | 用於皮下投藥之醫藥調配物 |
| US11389409B2 (en) * | 2019-08-30 | 2022-07-19 | Remedy Diagnostics LLC | Transdermal device comprising acetaminophen prodrug |
| JP7810970B2 (ja) | 2020-02-05 | 2026-02-04 | シーポート・セラピューティクス・インコーポレイテッド | 神経ステロイドの脂質プロドラッグ |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2444043A1 (fr) * | 1978-12-15 | 1980-07-11 | Bottu | Nouveau derive du paracetamol, son procede de preparation et son utilisation en therapeutique |
| DK406686D0 (da) * | 1986-08-26 | 1986-08-26 | Hans Bundgaard | Carboxylsyrederivater |
| US5001115A (en) * | 1989-05-17 | 1991-03-19 | University Of Florida | Prodrugs of biologically active hydroxyaromatic compounds |
| EP0510080A4 (en) * | 1989-12-26 | 1992-12-02 | Nova Pharmaceutical Corporation | Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use |
| US5627165A (en) * | 1990-06-13 | 1997-05-06 | Drug Innovation & Design, Inc. | Phosphorous prodrugs and therapeutic delivery systems using same |
| US5272171A (en) * | 1992-02-13 | 1993-12-21 | Bristol-Myers Squibb Company | Phosphonooxy and carbonate derivatives of taxol |
| US6750216B2 (en) * | 1996-03-08 | 2004-06-15 | Adolor Corporation | Kappa agonist compounds and pharmaceutical formulations thereof |
| IT1282736B1 (it) * | 1996-05-21 | 1998-03-31 | Angelini Ricerche Spa | Uso di derivati del p-amminofenolo per preparare composizioni farmaceutiche utili nel trattamento di malattie neurodegenerative |
| ATE222914T1 (de) * | 1997-05-15 | 2002-09-15 | Drug Innovation & Design Inc | Diester-derivate von acyclovir |
| AU754965B2 (en) * | 1997-12-31 | 2002-11-28 | University Of Kansas, The | Water soluble prodrugs of tertiary amine containing drugs and methods of making thereof |
| DK1056754T3 (da) * | 1998-01-29 | 2004-02-16 | Bristol Myers Squibb Co | Phosphatderivater af diaryl-1,3,4-oxadiazolon |
| US6204257B1 (en) | 1998-08-07 | 2001-03-20 | Universtiy Of Kansas | Water soluble prodrugs of hindered alcohols |
| US8231899B2 (en) * | 1998-09-10 | 2012-07-31 | Nycomed Danmark Aps | Quick release pharmaceutical compositions of drug substances |
| EA004032B1 (ru) * | 1998-09-10 | 2003-12-25 | Нюкомед Данмарк А/С | Фармацевтические композиции лекарственных веществ с быстрым высвобождением |
| US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
| US6362172B2 (en) * | 2000-01-20 | 2002-03-26 | Bristol-Myers Squibb Company | Water soluble prodrugs of azole compounds |
| CZ20023116A3 (cs) * | 2000-03-29 | 2003-01-15 | Altana Pharma Ag | Alkylované imidazopyridinové sloučeniny |
| NZ529661A (en) * | 2001-06-05 | 2006-03-31 | Control Delivery Systems | Sustained-release analgesic compounds |
| ATE373644T1 (de) * | 2002-02-05 | 2007-10-15 | Bristol Myers Squibb Co | N-substituierte 3-hydroxy-4-pyridinone und diese enthaltende pharmazeutika |
| US20040058946A1 (en) * | 2002-07-05 | 2004-03-25 | Buchwald Stephen L. | Abuse-resistant prodrugs of oxycodone and other pharmaceuticals |
| WO2004043493A1 (en) * | 2002-11-14 | 2004-05-27 | Syntarga B.V. | Prodrugs built as multiple self-elimination-release spacers |
| US20040186081A1 (en) * | 2003-03-03 | 2004-09-23 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating opioid tolerance |
| MXPA05009757A (es) * | 2003-03-13 | 2005-12-05 | Controlled Chemicals Inc | Conjugados de oxicodona con menor potencial de abuso y duracion de accion extendida. |
| AU2003901813A0 (en) * | 2003-04-15 | 2003-05-01 | Vital Health Sciences Pty Ltd | Pharmaceutical derivatives |
| US20050080260A1 (en) * | 2003-04-22 | 2005-04-14 | Mills Randell L. | Preparation of prodrugs for selective drug delivery |
| US6992090B2 (en) * | 2003-06-16 | 2006-01-31 | Adolor Corporation | Substituted piperidine compounds and methods of their use |
| US20050026879A1 (en) * | 2003-07-31 | 2005-02-03 | Robinson Cynthia B. | Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a tyrosine kinase inhibitor, delta opioid receptor antagonist, neurokinin receptor antagonist, or VCAM inhibitor for treatment of asthma or chronic obstructive pulmonary disease |
| US20070093457A1 (en) * | 2004-02-11 | 2007-04-26 | Nadir Arber | Compositions for treatment of cancer and inflammation with curcumin and at least one nsaid |
| EP1773850B1 (en) | 2004-07-06 | 2013-01-30 | Abbott Laboratories | Prodrugs of hiv protease inhibitors |
| EP2121029A2 (en) * | 2006-12-05 | 2009-11-25 | Neurogesx, Inc. | Prodrugs and methods of making and using the same |
| AU2009249071A1 (en) | 2008-05-20 | 2009-11-26 | Neurogesx, Inc. | Hepatoprotectant acetaminophen mutual prodrugs |
| JP5757864B2 (ja) | 2008-05-20 | 2015-08-05 | ニューロジェシックス, インコーポレイテッド | 水溶性アセトアミノフェン類似体 |
| AU2009249069A1 (en) | 2008-05-20 | 2009-11-26 | Neurogesx, Inc. | Carbonate prodrugs and methods of using the same |
| US8569466B2 (en) | 2008-09-10 | 2013-10-29 | Nnochiri Ekwuribe | Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers |
| JP2012520342A (ja) | 2009-03-16 | 2012-09-06 | ジェンメディカ・セラピューティックス・ソシエダッド・リミターダ | 代謝障害を処置するのに有用な抗炎症剤および抗酸化剤のコンジュゲート |
| EP2758133A4 (en) | 2011-09-22 | 2015-05-27 | Acorda Therapeutics Inc | ACETAMINOPHONE CONJUGATES, COMPOSITIONS AND METHOD OF USE THEREOF |
-
2009
- 2009-05-20 JP JP2011510691A patent/JP5757864B2/ja not_active Expired - Fee Related
- 2009-05-20 KR KR1020107027998A patent/KR101698028B1/ko not_active Expired - Fee Related
- 2009-05-20 US US12/993,088 patent/US20110212926A1/en not_active Abandoned
- 2009-05-20 AU AU2009249067A patent/AU2009249067A1/en not_active Abandoned
- 2009-05-20 MX MX2010012648A patent/MX2010012648A/es active IP Right Grant
- 2009-05-20 WO PCT/US2009/044743 patent/WO2009143295A1/en not_active Ceased
- 2009-05-20 CN CN2009801282182A patent/CN102149672A/zh active Pending
- 2009-05-20 RU RU2010151952/04A patent/RU2010151952A/ru not_active Application Discontinuation
- 2009-05-20 CA CA2724877A patent/CA2724877C/en not_active Expired - Fee Related
- 2009-05-20 CN CN201510381430.7A patent/CN105254662A/zh active Pending
- 2009-05-20 EP EP09751523.3A patent/EP2291348A4/en not_active Withdrawn
- 2009-05-20 BR BRPI0912326A patent/BRPI0912326A2/pt not_active IP Right Cessation
-
2010
- 2010-11-17 IL IL209382A patent/IL209382A0/en unknown
-
2014
- 2014-03-13 JP JP2014049672A patent/JP2014111658A/ja not_active Withdrawn
-
2016
- 2016-02-01 JP JP2016016971A patent/JP6063072B2/ja not_active Expired - Fee Related
- 2016-03-22 US US15/077,802 patent/US9981998B2/en not_active Expired - Fee Related
- 2016-12-15 JP JP2016242968A patent/JP2017057217A/ja not_active Withdrawn
-
2018
- 2018-04-25 US US15/962,934 patent/US10442826B2/en not_active Expired - Fee Related
- 2018-05-23 JP JP2018098716A patent/JP2018135392A/ja not_active Withdrawn
-
2019
- 2019-09-09 US US16/565,173 patent/US11021498B2/en not_active Expired - Fee Related
-
2020
- 2020-04-20 JP JP2020074690A patent/JP2020114876A/ja not_active Withdrawn
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